Search results for "Chloride"

showing 10 items of 1691 documents

Anthocyanins of Coloured Wheat Genotypes in Specific Response to SalStress

2018

The present study investigated the effect of salt stress on the development of adaptive responses and growth parameters of different coloured wheat genotypes. The different coloured wheat genotypes have revealed variation in the anthocyanin content, which may affect the development of adaptive responses under increasing salinity stress. In the early stage of treatment with salt at a lower NaCl concentration (100 mM), anthocyanins and proline accumulate, which shows rapid development of the stress reaction. A dose-dependent increase in flavonol content was observed for wheat genotypes with more intense purple-blue pigmentation after treatment with 150 mM and 200 mM NaCl. The content of Na⁺ a…

0106 biological sciences0301 basic medicineflavonolMDAColorPharmaceutical ScienceSodium Chloride01 natural sciencesArticleSalinity stressAnalytical Chemistrysalinitylcsh:QD241-44103 medical and health scienceschemistry.chemical_compoundlcsh:Organic chemistryDry weightStress PhysiologicalwheatDrug DiscoveryGenotypeDry matterProlinePhysical and Theoretical ChemistryprolineTriticumPigmentationChemistryOrganic Chemistryfood and beveragesSalt ToleranceanthocyaninsSalinityHorticulture030104 developmental biologyChemistry (miscellaneous)AnthocyaninMolecular MedicineAfter treatment010606 plant biology & botanyMolecules
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Effect of NaCl road salt on the ionic composition of soils and Aesculus hippocastanum L. foliage and leaf damage intensity.

2021

AbstractWe investigated the accumulation of sodium chloride in roadside soils and common horse chestnut Aesculus hippocastanum L. under urban conditions to evaluate changes in soil and leaf ionic content and their relationship with foliar damage, considering the visual assessment of trees of the same health status. A total of 15 field sites were assessed in late June 2016. The analysis included soil granulometric composition, pH, electrical conductivity, and the content of Cl−, Na+, K+, Ca2+, and Mg2+ ions in soil and foliage samples. The results showed increased salinity and alkalization of roadside soils together with the decreased magnesium content. Foliage samples manifested significant…

0106 biological sciencesAesculus hippocastanumSodiumSciencechemistry.chemical_element010501 environmental sciences01 natural sciencesChlorideArticleNutrientmedicine0105 earth and related environmental sciencesMultidisciplinaryChemistryMagnesiumQRSalinityEnvironmental sciencesHorticultureSoil waterMedicineComposition (visual arts)Plant sciences010606 plant biology & botanymedicine.drugScientific reports
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Carbamazepine, cadmium chloride and polybrominated diphenyl ether-47, synergistically modulate the expression of antioxidants and cell cycle biomarke…

2019

Abstract A wide range of contaminants, industrial by-products, plastics, and pharmaceutics belonging to various categories, have been found in sea water. Although these compounds are detected at concentrations that might be considered as sub-lethal, under certain conditions they could act synergistically producing unexpected effects in term of toxicity or perturbation of biochemical markers leading to standard pathway. In this study, the Sparus aurata fibroblast cell line SAF-1, was exposed to increasing concentrations of carbamazepine (CBZ), polybrominated diphenyl ether 47 (BDE-47) and cadmium chloride (CdCl2) until 72 h, to evaluate the cytotoxicity and the expression of genes related to…

0106 biological sciencesAntioxidantmedicine.medical_treatmentAquatic ScienceCadmium chlorideOceanographymedicine.disease_cause010603 evolutionary biology01 natural sciencesCell LinePolybrominated diphenyl-etherchemistry.chemical_compoundCadmium ChlorideSettore AGR/20 - ZoocoltureSettore BIO/10 - BiochimicaHalogenated Diphenyl EthersmedicineAnimalsoxidative stressSparus aurata fibroblastSettore BIO/06 - Anatomia Comparata E CitologiaCytotoxicity010604 marine biology & hydrobiologyCell CycleDiphenyl etherbiomarkersBiomarkerGeneral MedicineCell cycleCadmium chloridePollutionEnzyme ActivationOxidative StressCarbamazepineGene Expression RegulationchemistryBiochemistry:5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citología [CDU]Cell culturecarbamazepineToxicityOxidative streEnergy MetabolismOxidoreductasespolybrominated diphenyl-etherBiomarkersWater Pollutants ChemicalOxidative stressMarine Environmental Research
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Effect of gender on physiological and behavioural responses of Gammarus roeseli (Crustacea Amphipoda) to salinity and temperature.

2010

8 pages; International audience; The importance of potentially interacting factors in organisms responses to a stress are often ignored or underestimated in ecotoxicology. In laboratory experiments we investigated how gender, temperature and age influence the behaviour and the physiology of the freshwater amphipod Gammarus roeseli under salinity stress. Our results revealed a significant higher sensitivity of females in survival, ventilation and ionoregulation whereas no inter-age differences were reported. Water temperature also exerted a significant effect in survival and ventilation of G. roeseli. Some of those factors appeared to interact significantly. This study provides evidence that…

0106 biological sciencesMaleSalinityAmphipodaPhysiologyHealth Toxicology and Mutagenesis010501 environmental sciencesSodium ChlorideToxicologymedicine.disease_cause01 natural sciences[ SDV.EE ] Life Sciences [q-bio]/Ecology environment[SDV.EE.ECO]Life Sciences [q-bio]/Ecology environment/EcosystemsSalinity stressSpecies SpecificityGender effectGammarus roeselimedicineEcotoxicologyAnimalsAmphipodaBehaviourComputingMilieux_MISCELLANEOUSGammarus roeseli0105 earth and related environmental sciences[SDV.EE]Life Sciences [q-bio]/Ecology environment[ SDE.BE ] Environmental Sciences/Biodiversity and EcologybiologyBehavior AnimalEcology010604 marine biology & hydrobiologyStressorEnvironmental factorTemperatureGeneral Medicinebiology.organism_classificationPollutionCrustacean6. Clean waterSalinityBreathingFemale[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Application of a compositional rotatable plan in modeling the propylene content in a vinyl chloride/propylene copolymer

2019

Abstract Using a fractional rotatable plan, the effect of five input parameters of the conduct of the copolymerization process on the amount of propylene built into the copolymer, obtained as a result of free radical suspension copolymerization of vinyl chloride with propylene in a batch suspension polymerization reactor, was analyzed. Using the results obtained, the analysis of variance was carried out and the influence of particular factors and their interactions on the product properties was determined. Thus, it was determined that the greatest influence on the amount of the incorporated propylene in the copolymer is exerted by the amount of propylene introduced into the system, while th…

0209 industrial biotechnologyMaterials sciencePolymers and Plastics02 engineering and technologyGeneral Chemistry021001 nanoscience & nanotechnologyCondensed Matter PhysicsVinyl chloridechemistry.chemical_compound020901 industrial engineering & automationchemistryChemical engineeringContent (measure theory)Materials ChemistryCopolymerSuspension polymerization0210 nano-technologySuspension (vehicle)Polymer Bulletin
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Sodium functions as a negative allosteric modulator of the oxytocin receptor

2017

Abstract The oxytocin receptor, a class A G protein coupled receptor (GPCR), is essentially involved in the physiology of reproduction. Two parameters are crucially important to support high-affinity agonist binding of the receptor: Mg2+ and cholesterol, both acting as positive modulators. Using displacement assays with a high-affinity fluorescent antagonist (OTAN-A647), we now show that sodium functions as a negative allosteric modulator of the oxytocin receptor. In membranes from HEK293 cells stably expressing the oxytocin receptor, oxytocin binding occurred with about 15-fold lower affinity when sodium chloride was increased from 0 to 300 mM, whereas antagonist binding remained largely u…

0301 basic medicineAgonistAllosteric modulatormedicine.drug_classSodiumBiophysicschemistry.chemical_elementBreast NeoplasmsSodium ChlorideOxytocinBiochemistryPotassium Chloride03 medical and health sciencesAllosteric RegulationCell Line TumormedicineHumansAmino Acid SequenceReceptorFluorescent DyesG protein-coupled receptorDose-Response Relationship DrugSequence Homology Amino AcidChemistryCell MembraneCell BiologyOxytocin receptorRecombinant ProteinsCell biologyCholesterolHEK293 Cells030104 developmental biologyOxytocinReceptors OxytocinMutagenesis Site-DirectedCalciumFemaleSequence Alignmenthormones hormone substitutes and hormone antagonistsIntracellularProtein Bindingmedicine.drugBiochimica et Biophysica Acta (BBA) - Biomembranes
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27Al NMR Study of the pH Dependent Hydrolysis Products of Al2(SO4)3 in Different Physiological Media

2018

Soluble inorganic aluminium compounds like aluminium sulfate or aluminium chloride have been challenged by the European Chemical Agency to induce germ cell mutagenicity. Before conducting mutagenicity tests, the hydrolysis products in water and in physiological solutions should be determined as a function of the concentration and pH. We used different 27Al NMR spectroscopic techniques (heteronuclear Overhauser effect spectroscopy (HOESY), exchange spectroscopy (EXSY), diffusion ordered (DOSY)) in this work to gain the information to study the aluminium species in solutions with Al2(SO4)3 concentrations of 50.0, 5.0, and 0.5 g/L and their pH and time dependent transformation. At low pH, thre…

0301 basic medicineAluminium chlorideInorganic chemistryPharmaceutical Sciencechemistry.chemical_elementNuclear Overhauser effectAluminium sulfate010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-44103 medical and health scienceschemistry.chemical_compoundHydrolysislcsh:Organic chemistryAluminiumDrug DiscoverymedicinePhysical and Theoretical Chemistrychemistry.chemical_classificationOrganic ChemistryNMR0104 chemical sciences030104 developmental biologyhydrolysischemistryHeteronuclear moleculeChemistry (miscellaneous)REACHMolecular MedicineCounterionaluminium sulfate; hydrolysis; NMR; REACHaluminium sulfateTwo-dimensional nuclear magnetic resonance spectroscopymedicine.drugMolecules; Volume 23; Issue 4; Pages: 808
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The application protocol impacts the effectiveness of biocides against lichens

2020

Abstract This work analyzed the influence of different application protocols on the efficacy of two biocides against the foliose lichen Xanthoparmelia tinctina on the sandstones of the Roman Archaeological site of Luni (Italy). The hypotheses that (a) biocide application tools (brush vs. poultice), (b) pre-treatment hydration, and (c) post-treatment washing may affect devitalization success were verified by monitoring chlorophyll a fluorescence of thalli, both in situ and in laboratory conditions. The hypothesis that (d) stone substrate may act as reservoir for later biocide release under repeated cycles of wetting and drying was also assayed. Analyses confirmed the importance of the applic…

0301 basic medicineBiocide030106 microbiologyFoliose lichenLichenBenzalkonium chloride010501 environmental sciences01 natural sciencesMicrobiologyBiomaterials03 medical and health sciencesBenzalkonium chloridechemistry.chemical_compoundAdsorptionChlorophyll a fluorescencemedicineCelluloseThallus hydrationLichenWaste Management and DisposalBenzalkonium chloride Chlorophyll a fluorescence Lichen Thallus hydration Stone conservation0105 earth and related environmental sciencesChemistryBenzalkonium chloride; Chlorophyll a fluorescence; Lichen; Stone conservation; Thallus hydrationPoulticeThallusEnvironmental chemistryStone conservationmedicine.drugInternational Biodeterioration & Biodegradation
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NaCl-saturated brines are thermodynamically moderate, rather than extreme, microbial habitats

2018

NaCl-saturated brines such as saltern crystalliser ponds, inland salt lakes, deep-sea brines and liquids-of-deliquescence on halite are commonly regarded as a paradigm for the limit of life on Earth. There are, however, other habitats that are thermodynamically more extreme. Typically, NaCl-saturated environments contain all domains of life and perform complete biogeochemical cycling. Despite their reduced water activity, ∼0.755 at 5 M NaCl, some halophiles belonging to the Archaea and Bacteria exhibit optimum growth/metabolism in these brines. Furthermore, the recognised water-activity limit for microbial function, ∼0.585 for some strains of fungi, lies far below 0.755. Other biophysical c…

0301 basic medicineBiogeochemical cycleWater activity030106 microbiologySodium Chlorideengineering.materialBacterial Physiological PhenomenaMicrobiology03 medical and health sciencesEcosystemEcosystemBacteriabiologyBiospherebiology.organism_classificationArchaeaHalophile030104 developmental biologyInfectious DiseasesEnvironmental chemistryengineeringDunaliella salinaThermodynamicsHaliteSaltsWater MicrobiologyArchaeaFEMS Microbiology Reviews
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PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFα.

2018

Abstract Lung cancer is the leading cause of cancer-related death worldwide, in large part due to its high propensity to metastasize and to develop therapy resistance. Adaptive responses to hypoxia and epithelial–mesenchymal transition (EMT) are linked to tumor metastasis and drug resistance, but little is known about how oxygen sensing and EMT intersect to control these hallmarks of cancer. Here, we show that the oxygen sensor PHD3 links hypoxic signaling and EMT regulation in the lung tumor microenvironment. PHD3 was repressed by signals that induce EMT and acted as a negative regulator of EMT, metastasis, and therapeutic resistance. PHD3 depletion in tumors, which can be caused by the EM…

0301 basic medicineCancer ResearchEpithelial-Mesenchymal TransitionLung NeoplasmsMice NudeAntineoplastic AgentsSMADDrug resistanceMetastasisHypoxia-Inducible Factor-Proline DioxygenasesMitochondrial Proteins03 medical and health sciencesErlotinib HydrochlorideMice0302 clinical medicineDownregulation and upregulationCell Line TumorTumor MicroenvironmentMedicineAnimalsHumansNeoplasm MetastasisLung cancerProtein Kinase InhibitorsEGFR inhibitorsbusiness.industryIntracellular Signaling Peptides and ProteinsCancerTransforming Growth Factor alphamedicine.diseaseHCT116 CellsXenograft Model Antitumor AssaysCell HypoxiaErbB Receptors030104 developmental biologyOncologyA549 CellsDrug Resistance Neoplasm030220 oncology & carcinogenesisembryonic structuresCancer researchFemaleErlotinibbusinessApoptosis Regulatory Proteinsmedicine.drugCancer research
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