Search results for "Chronic pain"
showing 10 items of 257 documents
User-Centred Design with a Remote Approach: Experiences from the Chronic Pain Project
2020
User-centred design involves end-users or user groups during all the parts of the development process. The research project Chronic Pain aims to develop a shared decision making application for patients and physicians, addressing individually adapted pain treatment. The project employs a user-centred design process, and in middle of it, Covid-19 pandemic social distancing restrictions were imposed. This paper presents how the user-centred design process together with a patient organisation was transformed to a digital approach and the experiences from performing a remote co-creation user workshop. The digital approximation had a satisfactory result and the main contribution lies in the shar…
Human brain mechanisms of pain perception and regulation in health and disease
2005
Context: The perception of pain due to an acute injury or in clinical pain states undergoes substantial processing at supraspinal levels. Supraspinal, brain mechanisms are increasingly recognized as playing a major role in the representation and modulation of pain experience. These neural mechanisms may then contribute to interindividual variations and disabilities associated with chronic pain conditions. Objective: To systematically review the literature regarding how activity in diverse brain regions creates and modulates the experience of acute and chronic pain states, emphasizing the contribution of various imaging techniques to emerging concepts. Data Sources: MEDLINE and PRE-MEDLINE s…
Role of Levo-tetrahydropalmatine and its metabolites for management of chronic pain and opioid use disorders.
2021
Abstract Background Opioids have been prescribed to reduce suffering from pain and to enhance quality of life. Due to the addictive potential and the lack of other effective alternatives to treat severe acute and chronic pains, opioids remain a serious public health issue. While, opioids directly influence the drug-seeking behavior, tolerance and withdrawal processes, through neuroadaptation, the brain's endogenous opioid system also adapts in the presence of chronic pain and could contribute to the difficulty of treatment. Despite the seemingly obvious interaction between the presence of pain and opioid-abuse, little is known about the underlying mechanisms in the brain. Purpose To review …
Effects of Antidepressants on Inhibitory Avoidance in Mice: A Review
2012
Neither the biological basis of depression (Nemeroff & Vale, 2005; Kasper & McEwen, 2008) nor the precise mechanism of antidepressant efficacy are completely understood (Dudra-Jastrzebska et al., 2007). Indeed, antidepressants are widely prescribed for anxiety and disorders other than depression. For example, they are the drug therapy of choice for severe anxiety disorders such as agoraphobia, generalized anxiety disorder, social phobia, obsessive-compulsive disorder and post-traumatic stress disorder (Baldessarini, 2001). Antidepressants are also employed as a therapeutic tool in disorders such as drug addition (e.g. Schatzberg, 2000), enuresis (e.g. Humphreys & Reinberg, 2005) and chronic…
Ecological momentary assessment for chronic pain in fibromyalgia using a smartphone: A randomized crossover study
2013
Background Daily diaries are a useful way of measuring fluctuations in pain-related symptoms. However, traditional diaries do not assure the gathering of data in real time, not solving the problem of retrospective assessment. Ecological momentary assessment (EMA) by means of electronic diaries helps to improve repeated assessment. However, it is important to test its feasibility in specific populations in order to reach a wider number of people who could benefit from these procedures. Methods The present study compares the compliance and acceptability of an electronic diary running on a smartphone using a crossover design for a sample with a specific pain condition, fibromyalgia and low fam…
Low back pain, work absenteeism, chronic back disorders, and clinical findings in the low back as predictors of hospitalization due to low back disor…
2005
Study Design. Prospective cohort study. Objective. To study symptoms, chronic disorders, and clinical findings in the low back, and work absenteeism, as predictors of hospitalization. Summary of Background Data. Socioeconomic and lifestyle factors are associated with back-related hospitalization, but the significance in the working normal population of low back symptoms and clinical findings are not known. Methods. The cohort (n = 902) was drawn in 1973 from among employees in the metal industry (n = 2,653). The data were collected by questionnaire and a structured clinical assessment by a physiotherapist. Weight was measured. A sum score of local and radiating low back symptoms (frequency …
La Prevalenza del Dolore Cronico Non Oncologico nell’Adulto e Patologie Associate: Una revisione narrativa
2013
Introduzione: Il dolore cronico non oncologico rappresenta un problema sanitario sottostimato dal punto di vista epidemiologico ed in termini di salute pubblica. Esso è una malattia in senso stretto, e rappresenta una delle maggiori motivazioni per cui i soggetti si rivolgono ai servizi sanitari. La grandezza del fenomeno si esprime in termini di sofferenza umana e di costi sociali. L’obiettivo di questa revisione è quello di identificare le cause e la prevalenza del dolore cronico non oncologico nei soggetti adulti. Metodi: E’ stata realizzata una revisione della letteratura dal 1998 al 2012 utilizzando le emeroteche virtuali partendo dalle banche dati (Pub-Med, CINHAL). È stata effettuata…
Music reduces pain and increases functional mobility in fibromyalgia
2014
The pain in Fibromyalgia (FM) is difficult to treat and functional mobility seems to be an important comorbidity in these patients that could evolve into a disability. In this study we wanted to investigate the analgesic effects of music in FM pain. Twenty-two FM patients were passively exposed to (1) self-chosen, relaxing, pleasant music, and to (2) a control auditory condition (pink noise). They rated pain and performed the "timed-up & go task (TUG)" to measure functional mobility after each auditory condition. Listening to relaxing, pleasant, self-chosen music reduced pain and increased functional mobility significantly in our FM patients. The music-induced analgesia was significantly co…
Chronischer Schmerz: Epidemiologie und Inanspruchnahme
2001
Die “Pravalenz” chronischer Schmerzen in der Allgemeinbevolkerung reicht je nach Untersuchung und Definition von 10% bis uber 40%. Chronische Schmerzen sind mit hohen direkten und indirekten Kosten fur das Gesundheitswesen auf der einen Seite und einer erheblichen personlichen Beeintrachtigungen der Lebensqualitat des Einzelnen auf der anderen Seite verbunden. Die vorliegende Arbeit gibt eine Ubersicht uber Haufigkeit und Verteilung chronischer Schmerzen in der Allgemeinbevolkerung und bei Inanspruchnahmepopulationen. Die Grenzen epidemiologischer Untersuchungen liegen in der Schwierigkeit eine subjektive innere Erfahrung moglichst valide zu erfassen, zudem ist das Stellen von Diagnosen im …
The effectiveness of hypnosis for pain relief: A systematic review and meta-analysis of 85 controlled experimental trials.
2019
The current meta-analysis aimed to quantify the effectiveness of hypnosis for reducing pain and identify factors that influence efficacy. Six major databases were systematically searched for trials comparing hypnotic inductions with no-intervention control conditions on pain ratings, threshold and tolerance using experimentally-evoked pain models in healthy participants. Eighty-five eligible studies (primarily crossover trials) were identified, consisting of 3632 participants (hypnosis n = 2892, control n = 2646). Random effects meta-analysis found analgesic effects of hypnosis for all pain outcomes (g = 0.54-0.76, p’s<.001). Efficacy was strongly influenced by hypnotic suggestibility and u…