Search results for "Clinical case"

showing 10 items of 72 documents

Endocarditis due to Abiotrophia defectiva, a biofilm-related infection associated with the presence of fixed braces

2017

Abstract Rationale: Endocarditis with Abiotrophia defectiva represents 4.3% to 6% of all streptococcal endocarditis. The article presents diagnosis issues and the complexity of the treatment. Patient concerns: We present the case of a female white patient, aged 26 years, who developed infectious endocarditis caused by A defectiva, in the last trimester of pregnancy, a biofilm-related infection associated with the presence of fixed braces. Diagnoses: The diagnosis of infectious endocarditis was confirmed by the cardiac ultrasound examination that revealed a voluminous vegetation on the mitral valve, and acute mitral regurgitation caused by chordae tendinae rupture, and also by isolating Abio…

Adult0301 basic medicinemedicine.medical_specialtyProsthesis-Related Infectionsmedicine.drug_classmedicine.medical_treatment030106 microbiologyAntibioticsbiofilm03 medical and health sciences0302 clinical medicinePregnancyAbiotrophiaMitral valvemedicineHumansEndocarditisClinical Case Report030212 general & internal medicinePregnancy Complications InfectiousAbiotrophia defectivaGram-Positive Bacterial InfectionsAbiotrophia defectivaBracesinfectious endocarditisbiology4900business.industryMitral valve replacementEndocarditis BacterialGeneral MedicineAbiotrophiabiology.organism_classificationmedicine.diseaseSurgerymedicine.anatomical_structureEmbolismBiofilmsInfective endocarditisFemalebusinessResearch ArticleMedicine
researchProduct

Haemorheological profile in congenital afibrinogenemia and in congenital dysfibrinogenemia: A clinical case report

2019

Although the inherited quantitative and qualitative disorders of fibrinogen are rare, in the course of time patients may develop complications including episodes of arterial and venous thrombosis. It can be useful to complete the laboratory assessment of these clinical conditions with the evaluation of the haemorheological profile. The data obtained from this study showed that congenital afibrinogenemia was characterized by a primary plasma hypoviscosity, whereas congenital dysfibrinogenemia by a primary plasma hyperviscosity. Both these haemorheological alterations may concur, with different mechanisms, to the pathogenesis of thrombotic vascular complications.

AdultMaleHypoviscosityPediatricsmedicine.medical_specialtyPhysiologyHyperviscosity030204 cardiovascular system & hematologyFibrinogen030218 nuclear medicine & medical imagingYoung Adult03 medical and health sciences0302 clinical medicinePhysiology (medical)medicineHumansAfibrinogenemiabusiness.industryCongenital dysfibrinogenemiaFibrinogenHematologyMiddle AgedAfibrinogenemiamedicine.diseaseCongenital afibrinogenemiaVenous thrombosisFemaleClinical caseCardiology and Cardiovascular MedicinebusinessHumanmedicine.drugClinical Hemorheology and Microcirculation
researchProduct

Five years experience on 3,4-diaminopyridine phosphate in Lambert-Eaton syndrome: Case reports

2017

Abstract Rationale: To report our experience on 7 patients (4 males and 3 females), affected by nonparaneoplastic Lambert–Eaton myasthenic syndrome, treated with 3,4-diaminopyridine phosphate (3,4-DAPP) either alone or in combination with other immunosuppressants or steroids. Patient concerns: Patients have been evaluated at specific timepoints (ie, baseline and last 5 year follow-up), with neurological examination, autoantibodies against presynaptic voltage-gated Cav2.1 (P/Q type) calcium ion channel (VGCC) dosage, neurophysiological evaluation focusing on the increased amplitude of the compound muscle action potential (cMAP) after maximum voluntary effort, quantitative myasthenia gravis (…

AdultMalemedicine.medical_specialtyAzathioprineNeurological examination030204 cardiovascular system & hematologySeverity of Illness Index5300nonparaneoplastic-Lambert–Eaton myasthenic syndrome03 medical and health sciences0302 clinical medicinePrednisoneInternal medicineSeverity of illnessActivities of Daily LivingAzathioprinemedicineHumansMuscle StrengthClinical Case Report4-AminopyridineAdverse effect34-diaminopyridine phosphate; nonparaneoplastic-Lambert-Eaton myasthenic syndrome; 4-Aminopyridine; Activities of Daily Living; Adult; Azathioprine; Drug Therapy Combination; Female; Humans; Immunosuppressive Agents; Lambert-Eaton Myasthenic Syndrome; Male; Middle Aged; Muscle Strength; Prednisone; Severity of Illness Index; Treatment Outcome; Medicine (all)medicine.diagnostic_testbusiness.industry34-diaminopyridine phosphateGeneral MedicineMiddle Agedmedicine.diseaseMyasthenia gravisLambert-Eaton Myasthenic SyndromeTreatment OutcomeConcomitantPrednisoneDrug Therapy CombinationFemaleAmifampridinebusinessLambert-Eaton myasthenic syndrome030217 neurology & neurosurgeryImmunosuppressive Agentsmedicine.drugResearch Article
researchProduct

A unique fatal case of Waterhouse–Friderichsen syndrome caused by Proteus mirabilis in an immunocompetent subject

2019

Abstract Introduction: The Waterhouse–Friderichsen syndrome (WFS), also known as purpura fulminans, is a potentially lethal condition described as acute hemorrhagic necrosis of the adrenal glands. It is often caused by infection. Classically, Neisseriae meningitidis represents the main microorganism related to WFS, although, infrequently, also other infectious agents are reported as a possible etiologic agent. The authors report the first case of death due to Proteus mirabilis infection, with postmortem evidence of WFS. Patient concerns: After a facial trauma that provoked a wound on the nose, the subject, a healthy 40-years old man, was conducted to the local hospital (in Sicily, Italy) af…

AdultMalemedicine.medical_specialtySepsiforensic sciencesAutopsyGastroenterologysepsisSepsisImmunocompromised Host03 medical and health sciences0302 clinical medicineSettore MED/43 - Medicina LegaleInternal medicinemedicineWaterhouse–Friderichsen syndromeHumansClinical Case Report030212 general & internal medicineLeukocytosisProteus mirabilisWaterhouse-Friderichsen syndromeDisseminated intravascular coagulationbiology4900business.industryBilateral massive adrenal hemorrhageWaterhouse-Friderichsen syndrome: XGeneral Medicinemedicine.diseasebiology.organism_classificationProteus InfectionProteus mirabilisBilateral massive adrenal hemorrhage; Forensic sciences; Proteus mirabilis infection; Sepsis; Waterhouse-Friderichsen syndrome; Adult; Humans; Male; Proteus Infections; Waterhouse-Friderichsen Syndrome; Immunocompromised Host; Proteus mirabilisProteus mirabilis infection030220 oncology & carcinogenesisForensic sciencemedicine.symptomProteus InfectionsbusinessAdrenal HemorrhageResearch ArticleHumanPurpura fulminansMedicine
researchProduct

Burkitt lymphoma associated with human immunodeficiency virus infection and pulmonary tuberculosis: A case report.

2019

Abstract Introduction: The association of human immunodeficiency virus (HIV) infection with Burkitt lymphoma is related to the presence of Epstein Barr virus infection and the impact of the HIV antigen on the expansion of B-polyclonal cells. In Southeast Europe, the association is rare, and recognizing this is important in the therapeutic decision to increase patient survival rate. The association of HIV with Burkitt lymphoma and tuberculosis is even more rarely described in the literature. Patient concerns: We present the case of a 40-year-old patient who presented with a 3-week history of fever (max. 38.7 °C), painful axillary swelling on the right side, lumbar pain, gait disorders, heada…

AdultMalemedicine.medical_specialtyTuberculosisAntitubercular AgentsAntineoplastic AgentsHIV Infectionshuman immunodeficiency virus infectionNeurosurgical ProceduresMycobacterium tuberculosis03 medical and health sciences0302 clinical medicinePharmacotherapyFatal Outcomeimmune system diseasesInternal medicinehemic and lymphatic diseasesAntiretroviral Therapy Highly ActivemedicineHumans030212 general & internal medicineClinical Case ReportEpstein–Barr virus infectionTuberculosis PulmonaryImmunodeficiencydose-adjusted etoposide doxorubicin and cyclophosphamide with vincristine prednisone and rituximabbiologyClinical Deteriorationbusiness.industry4900BrainBurkitt lymphomaGeneral MedicineViral Loadhighly active antiretroviral therapymedicine.diseasebiology.organism_classificationDecompression SurgicalLymphomaCD4 Lymphocyte CountSpinal Cord030220 oncology & carcinogenesisSputummedicine.symptombusinessViral loadpulmonary tuberculosisResearch ArticleMedicine
researchProduct

Blood and urinary abnormalities induced during and after 24-hour continuous running: A case report

2016

In this reported clinical case, a healthy and well-trained male subject [aged 37 years, maximal oxygen uptake (V[Combining Dot Above]O2max) 64 mL·kg·min] ran for 23 hours and 35 minutes covering 160 km (6.7 km/h average running speed). The analysis of hematological and biochemical parameters 3 days before the event, just after termination of exercise, and after 24 and 48 hours of recovery revealed important changes on muscle and liver function, and hemolysis. The analysis of urine sediments showed an increment of red and white blood cells filtrations, compatible with transient nephritis. After 48 hours, most of these alterations were recovered. Physicians and health professionals who monito…

AdultMalemedicine.medical_specialtyUrinary systemPhysiologyPhysical Therapy Sports Therapy and RehabilitationUrine030204 cardiovascular system & hematologyHemolysisRunning03 medical and health sciences0302 clinical medicineAtletamedicineHumansOrthopedics and Sports MedicineMuscle SkeletalPathologicalNephritisbusiness.industryMedicina deportivaVO2 max030229 sport sciencesAtletasmedicine.diseaseHemolysisSurgeryLiverClinical caseLiver functionbusinessNephritisBiomarkers
researchProduct

Use of long acting injectable aripiprazole before and through pregnancy in bipolar disorder: a case report

2019

Abstract Background Long-acting injectable (LAI) antipsychotics for psychotic disorders provide advantages in treatment compliance, but data on their use in pregnancy are very limited. We present a clinical case of aripiprazole LAI use in pregnancy. Case presentation A 43-year-old woman diagnosed with bipolar disorder, with several relapses due to treatment interruption while trying to conceive. Finally, aripiprazole LAI treatment was planned by mutual agreement between doctor and the patient, who took aripiprazole LAI before and during pregnancy. She gave birth at 40 weeks to a 3500 g baby girl with no congenital malformations, who was healthy at 5 months after delivery. Conclusion As far …

AdultPediatricsmedicine.medical_specialtyTime FactorsBipolar disordermedicine.medical_treatmentvirusesAripiprazoleCase Report030226 pharmacology & pharmacyInjections IntramuscularAntipsychotic03 medical and health sciences0302 clinical medicineimmune system diseasesPregnancylcsh:RA1190-1270medicineHumansPharmacology (medical)Bipolar disorderAntipsychoticlcsh:Toxicology. PoisonsPharmacologyDosage FormsPregnancybusiness.industrylcsh:RM1-950Pregnancy Outcomevirus diseasesCongenital malformationsmedicine.diseasePregnancy ComplicationsLong actinglcsh:Therapeutics. PharmacologyTreatment interruptionLong-acting injectable aripiprazoleAripiprazoleFemaleClinical casebusinessmedicine.drugAntipsychotic AgentsFollow-Up StudiesBMC Pharmacology and Toxicology
researchProduct

Tuberous sclerosis complex with oral manifestations: A case report and literature review

2011

Introduction: Tuberous sclerosis complex (TSC) is a neurocutaneous syndrome produced by a number of genetic mutations. The disease is characterized by the development of benign tumors affecting different body systems. The most common oral manifestations of TSC are fibromas, gingival hyperplasia and enamel hypoplasia. Clinical Case: A 35-year-old woman diagnosed with TSC presented with a reactive fibroma of considerable size and rapid growth in the region of the right lower third molar. Discussion: In the present case the association of TSC with dental malpositioning gave rise to a rapidly evolving reactive fibroma of considerable diameter. Few similar cases can be found in the literature. P…

Adultcongenital hereditary and neonatal diseases and abnormalitiesPathologymedicine.medical_specialtyFibromaMalalties de la bocaTuberous sclerosisTuberous SclerosismedicineHumansneoplasmsGeneral DentistryTumorsGingival Neoplasmsbusiness.industryEsclerosi tuberosaEnamel hypoplasiaHyperplasia:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseFibromesnervous system diseasesstomatognathic diseasesMouth diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASTuberosis sclerosisFemaleSurgeryClinical caseFibromabusinessMedicina Oral Patología Oral y Cirugia Bucal
researchProduct

Acute liver failure and HELLP syndrome: A clinical case and literature review.

2021

Summary Background HELLP syndrome is a pregnancy-related liver disease associated with increased maternal and foetal mortality. In rare cases, it can lead to the development of a subcapsular hepatic haematoma as well as its rupture. This rupture is life-threatening if not urgently treated. Method We describe a clinical case of HELLP syndrome involving a ruptured subcapsular liver haematoma and contextualise this with a literature overview. Clinical case A 39-year-old woman of 40 weeks’ gestation presented to her local Emergency Department with symptoms and serology classically associated with HELLP syndrome. However, she clinically deteriorated and developed a ruptured subcapsular haematoma…

Adultmedicine.medical_specialtyHELLP SyndromeHELLP syndromemedicine.medical_treatmentLiver transplantation03 medical and health sciencesLiver disease0302 clinical medicinePregnancymedicineHumansHematomaHepatologybusiness.industryCesarean SectionLiver DiseasesGastroenterologyLiver failureEmergency Caesarean SectionEmergency departmentLiver Failure Acutemedicine.diseaseSurgery030220 oncology & carcinogenesisGestation030211 gastroenterology & hepatologyFemaleClinical casebusinessClinics and research in hepatology and gastroenterology
researchProduct

Compound odontoma erupting in the mouth: 4-year follow-up of a clinical case

1992

A case of a compound odontoma erupting in the oral cavity is presented: a follow-up study of 4 yr has been performed evaluating the possible relationship with a previous dental trauma. A discussion is presented concerning the etiologic aspects, clinical signs, diagnostic aids and therapeutic approaches to this type of lesion.

Cancer ResearchDentistryOral cavityDiagnostic aidPathology and Forensic MedicineLesionOdontomaOral and maxillofacial pathologyHumansMedicineTooth RootTooth UneruptedChildPalatal NeoplasmsDental traumabusiness.industryOdontomaCompound Odontomamedicine.diseaseIncisorOtorhinolaryngologyPeriodonticsFemaleClinical caseOral Surgerymedicine.symptombusinessFollow-Up StudiesJournal of Oral Pathology and Medicine
researchProduct