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RESEARCH PRODUCT
Acute liver failure and HELLP syndrome: A clinical case and literature review.
Fabiano PerdigaoAlessandra MazzolaFilomena ContiClaire GoumardFrédéric CharlotteOlivier ScattonMuhammad AtifBianca Magrosubject
Adultmedicine.medical_specialtyHELLP SyndromeHELLP syndromemedicine.medical_treatmentLiver transplantation03 medical and health sciencesLiver disease0302 clinical medicinePregnancymedicineHumansHematomaHepatologybusiness.industryCesarean SectionLiver DiseasesGastroenterologyLiver failureEmergency Caesarean SectionEmergency departmentLiver Failure Acutemedicine.diseaseSurgery030220 oncology & carcinogenesisGestation030211 gastroenterology & hepatologyFemaleClinical casebusinessdescription
Summary Background HELLP syndrome is a pregnancy-related liver disease associated with increased maternal and foetal mortality. In rare cases, it can lead to the development of a subcapsular hepatic haematoma as well as its rupture. This rupture is life-threatening if not urgently treated. Method We describe a clinical case of HELLP syndrome involving a ruptured subcapsular liver haematoma and contextualise this with a literature overview. Clinical case A 39-year-old woman of 40 weeks’ gestation presented to her local Emergency Department with symptoms and serology classically associated with HELLP syndrome. However, she clinically deteriorated and developed a ruptured subcapsular haematoma. She underwent an emergency Caesarean section at her initial hospital. Upon clinical stabilisation, she was transferred to our transplant unit for an urgent liver transplant. Conclusion LT is a life-saving procedure for patients with acute liver failure secondary to HELLP syndrome. These patients should be immediately referred to a high-volume transplant centre.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-03-01 | Clinics and research in hepatology and gastroenterology |