Search results for "Clos"

One-dimensional Mixed MHD Convection

2006

The parallel, fully developed flow of an electrically conducting fluid between plane parallel walls under the simultaneous influence of a driving pressure head, buoyancy, and magnetohydrodynamic (MHD) forces is studied. The fluid is assumed to be internally heated and the flow is modeled as one-dimensional and incompressible, while the Boussinesq approximation is adopted for the buoyancy terms. Analytical solutions are obtained for temperature, velocity and electrical potential under different electrical boundary conditions, forced to natural convection intensity ratios and values of the magnetic induction. Generalized working charts are presented which synthetically describe the system''s …

Independent friction-restitution modeling of two-disk collisions

2021

[EN] The oblique collisions between two axisymmetric disks moving on a flat horizontal surface are described in terms of impact modeling based on the assumption that normal and tangential restitution mechanisms operate independently of friction. Describing these mechanisms in terms of the usual Coulomb formulation, the model allows for an interpretation of some ¿anomalous¿ experimental data reported in the literature. These experimental data, corresponding to the variation of the coefficients of friction and tangential restitution with the impact angle, remained unexplained in classic formulations, are understood within the framework of the independent friction-restitution closure. Experime…

Closure to “Experimental Study of Central Baffle Flume” by F. Lotfi Kolavani, M. Bijankhan, C. Di Stefano, V. Ferro, and A. Mahdavi Mazdeh

2020

This is a Closure of the discussions on the paper “Experimental Study of Central Baffle Flume” by F. Lotfi Kolavani, M. Bijankhan, C. Di Stefano, V. Ferro, and A. Mahdavi Mazdeh

Closure to “New Stage-Discharge Equation for the SMBF Flume” by Francesco Giuseppe Carollo, Costanza Di Stefano, Vito Ferro, and Vincenzo Pampalone

2017

Clostridium perfringens identificēšana un uzskaitīšana dzeramajā ūdenī ar fluorescentās in situ hibridizācijas metodi

2017

Sporu-veidojošā C. perfringens ir nozīmīgs organisms ūdens vidē, ko izmanto kā indikatororganismu dzeramā ūdens kvalitātes noteikšanai. Turklāt šī baktērija un tās sporas ir noderīgas, lai brīdinātu par citu stresa rezistento patogēnu iespējamo klātbūtni dzeramajā ūdenī. Atbilstoši Ministru kabineta noteikumiem Nr. 235, Clostridium perfringens noteikšanai un uzskaitei jāizmanto membrānfiltrācija un tālāka mikroorganismu kultivēšana. Tomēr izpētīts, ka kultivēšanas metodes nespēj identificēt ūdenī esošus nekultivējamus bet dzīvotspējīgus mikroorganismus (VBNC). Fluorescentā in situ hibridizācija (FISH), nodrošina baktēriju identificēšanu to dabiskā vidē, un var būt izmantojama, ka alternatīv…

Evaluation of P-glycoprotein (abcb1a/b) modulation of [18F]fallypride in MicroPET imaging studies

2012

[(18)F]Fallypride ([(18)F]FP) is an important and routinely used D2/D3 antagonist for quantitative imaging of dopaminergic neurotransmission in vivo. Recently it was shown that the brain uptake of the structurally related [(11)C]raclopride is modulated by P-glycoprotein (P-gp), an important efflux transporter at the blood-brain barrier. The purpose of this study was to determine whether the brain uptake of [(18)F]FP is influenced by P-gp. For examination of this possible modulation microPET studies were performed in a rat and a mouse model. Hence, [(18)F]FP was applied to Sprague Dawley rats, half of them being treated with the P-gp inhibitor cyclosporine A (CsA). In a second experimental s…

Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds--implications for pharmacokinetics of selected substrates.

2004

Abstract The pharmacokinetics of antipsychotic drugs has become an integral part in understanding their pharmacodynamic activity and clinical effects. In addition to metabolism aspects, carrier-mediated transport, particularly secretion by ABC transporters, has been discussed as potentially relevant for this group of therapeutics. In this study, the psychoactive compounds perphenazine, flupentixol, domperidone, desmethyl clozapine, haloperidol, fluphenazine, fluvoxamine, olanzapine, levome-promazine, perazine, desmethyl perazine, clozapine, quetiapine and amisulpride were characterized in terms of P-glycoprotein (P-gp) affinity and transport. Experimental methods involved a radioligand disp…

Effects of extra-fine inhaled beclomethasone/formoterol on both large and small airways in asthma

2010

Background: Airway inflammation in asthma involves both large and small airways, and the combination of inhaled corticosteroids (ICS) and long acting beta-2 agonists (LABA) is the mainstay of therapy. Available inhaled combinations differ in terms of drug delivery to the lung and the ability to reach small airways. Aim: To evaluate whether treatment with an extra-fine inhaled combination provides additional effects vs a nonextra-fine combination on airway function. Methods: After a 1- to 4-week run-in period, patients with asthma were randomized to a double blind, double dummy, 12-week treatment with either extra-fine beclomethasone/formoterol (BDP/F) 400/24 lg daily or fluticasone propiona…

Nonthermally driven volatilome evolution of food matrices: The case of high pressure processing

2020

Abstract Background The adoption of innovative nonthermal processing as alternatives to conventional heating techniques in the food industry is mainly relied on their tremendous potential to simultaneously achieve preservation purposes and the maintenance of fresh-like characteristics and health benefits of final products. With increasing evaluation for the applicability of nonthermal processing, there remains, however, a great challenge for keeping the balance between the efficiency of microbial/enzymatic inactivation and the maintenance of sensory and nutritional characteristics. Accordingly, a timely summarization and elucidation of the response pattern and mechanism of related quality p…

Corporate governance and its implications for sustainability reporting quality in Latin American business groups

2020

Abstract This paper aims to study the factors determining the quality of sustainability reporting in Latin American business groups. Applying a logistic regression model, this study is pioneer in establishing how some distinct corporate variables of business groups influence disclosure quality of Corporate Social Responsibility practices in these groups in emerging economies. The results show that control concentration in the groups negatively affects the quality of sustainability reporting. Variables such as foreign ownership, the age of the business group and board size help business groups to improve the quality of their sustainability and voluntary disclosure practices. These results fo…