Search results for "Cod"

Dosing of caspofungin based on a pharmacokinetic/pharmacodynamic index for the treatment of invasive fungal infections in critically ill patients on …

2017

Abstract Introduction The study objective was to evaluate the efficacy of different dosages of caspofungin in the treatment of invasive candidiasis and aspergillosis, in relation to the probability of pharmacokinetic/pharmacodynamic (PK/PD) target attainment, using modelling and Monte Carlo simulations in critically ill adult patients on continuous haemodiafiltration. Methods Critically ill adult patients on continuous venovenous haemodiafiltration treated with caspofungin were analysed. A population PK model was developed. Four caspofungin dosing regimens were simulated: the licensed regimen, 70 mg/day, 100 mg/day or 200 mg/day. A PK/PD target was defined as the ratio between the area unde…

Quantum error correction against photon loss using multi-component cat states

2016

We analyse a generalised quantum error correction code against photon loss where a logical qubit is encoded into a subspace of a single oscillator mode that is spanned by distinct multi-component cat states (coherent-state superpositions). We present a systematic code construction that includes the extension of an existing one-photon-loss code to higher numbers of losses. When subject to a photon loss (amplitude damping) channel, the encoded qubits are shown to exhibit a cyclic behaviour where the code and error spaces each correspond to certain multiples of losses, half of which can be corrected. As another generalisation we also discuss how to protect logical qudits against photon losses,…

Time-resolved classification of dog brain signals reveals early processing of faces, species and emotion

2020

Dogs process faces and emotional expressions much like humans, but the time windows important for face processing in dogs are largely unknown. By combining our non-invasive electroencephalography (EEG) protocol on dogs with machine-learning algorithms, we show category-specific dog brain responses to pictures of human and dog facial expressions, objects, and phase-scrambled faces. We trained a support vector machine classifier with spatiotemporal EEG data to discriminate between responses to pairs of images. The classification accuracy was highest for humans or dogs vs. scrambled images, with most informative time intervals of 100–140 ms and 240–280 ms. We also detected a response sensitive…

Transcodage des nombres chez l'enfant : approche développementale, inter-linguistique et différentielle

2010

Number transcoding in children is a domain rarely investigated. The PhD goal is to test the main predictions allowed by the transcoding model “ADAPT” of Barrouillet et al. (2004) in particular its ADAPTBASIC version concerning transcoding at the beginning of learning. Unlike the other transcoding models (e.g., McCloskey on 1992), ADAPT is a developmental, asemantic and procedural model. In this research the concerned transcoding allows to shift the verbal form of number to Arabic form. This thesis questions the acquisition of transcoding and its development with learning, as well as the impact of the inter-linguistic and individual differences. To reach these objectives, we adopted a develo…

Visual Cortex Performs a Sort of Non-linear ICA

2010

Here, the standard V1 cortex model optimized to reproduce image distortion psychophysics is shown to have nice statistical properties, e.g. approximate factorization of the PDF of natural images. These results confirm the efficient encoding hypothesis that aims to explain the organization of biological sensors by information theory arguments.

Compact and Field Portable Biophotonic Sensors for Automated Cell Identification (Plenary Address)

2021

In this Plenary address paper, we overview recently published work for automated cell identification using 3D optical imaging in compact and field portable biophotonic sensors. Digital holographic microscopy systems and lensless pseudorandom phase encoding systems capture 3D information of biological cells and make highly accurate automated cell identification possible. Overviewed systems include sickle cell disease diagnosis based on spatio-temporal cell dynamics in a field-portable 3D-printed shearing digital holography as well as lensless cell identification of both single and multicell samples using pseudorandom phase encoding.

Robotic Pancreaticoduodenectomy: Technical Considerations

2017

Robotic surgery can help to overcome some technical limitations of laparoscopic pancreaticoduodenectomy thanks to EndoWrist instrumentations and the 3D view. Despite the potential benefits, its employment is still low and controversial. We focused on some important technical details crucial for a safe robotic pancreatectomy. After performing 52 robotic pancreatic resections that included 10 pancreatoduodenectomies, the authors describe their technique. The review of literature on robotic and laparoscopic duodenopancreatectomy is also performed in order to evaluate possible benefits of the robotic platform. We describe the step-by-step surgical procedure, analyzing all possible troubleshooti…

Influence of different approaches to the cerebellopontine angle on the function of the intermediate nerve

2007

Object Surgery in the cerebellopontine angle (CPA) is a standard procedure at many centers. Outcome is focused mainly on preservation of hearing and facial function postoperatively. The nonmotor part of the facial nerve, the intermediate nerve, is nearly neglected nowadays. Methods A retrospective study was designed, including a questionnaire that was sent to 178 patients who had undergone surgery between 2000 and 2004. Data were obtained in 156 cases. The questionnaire was divided into five parts assessing the presence of increased tearing, reduced tearing, salivation disturbances, increased nasal secretions, and abnormalities in taste. Finally, a self-assessment of patient symptoms was a…

Chloroplastic glutamine synthetase from Brassica napus.

1993

Zwitterionic codeine-derived methacrylate monoliths for enantioselective capillary electrochromatography of chiral acids and chiral bases

2018

Thiol-ene click reaction of N-acetyl-L-cysteine methyl ester to codeine, followed by reaction with allyl isocyanate and hydrolysis to the corresponding zwitterionic chiral selector and its subsequent bonding to the surface of a methacrylate monolith provided a new chiral capillary column for enantiomer separation of chiral acids and chiral bases. First, the epoxy groups of a poly(glycidyl methacrylate-co-ethylene dimethacrylate) monolith were converted into amine residues, followed by reaction with allylglycidyl ether. In this way, a spacer arm was bonded to the surface before coating and cross-linking poly(3-mercaptopropyl methylsiloxane) (PMPMS) via radical addition (thiol-ene click react…