Search results for "Coma"

showing 10 items of 1084 documents

Knowledge about glaucoma in the unselected population: a German survey.

2002

Purpose To determine the general population's knowledge about glaucoma. Materials and methods A representative survey of the German population was conducted in which 2,742 men and women were interviewed face to face. The sample was matched with the German population for age, sex, education, income, and other factors. Questions were asked concerning the nature, occurrence, possible risk factors, and course of glaucoma. Results Fifty-one percent of the population had an active knowledge of the term "glaucoma" and 75% had a passive knowledge of the term. Of those interviewees with a passive knowledge, glaucoma was thought to be associated with raised intraocular pressure (IOP) by 28% and loss …

AdultMaleIntraocular pressurePediatricsmedicine.medical_specialtyHealth Knowledge Attitudes Practicegenetic structuresAdolescentPopulationMEDLINEGlaucomaDiseaseGermanBlurred visionRisk FactorsSurveys and QuestionnairesmedicineHumanseducationIntraocular PressureAgedAged 80 and overeducation.field_of_studybusiness.industryMiddle Agedmedicine.diseaseeye diseaseslanguage.human_languageOphthalmologylanguageUnselected populationFemalesense organsmedicine.symptombusinessGlaucoma Open-AngleJournal of glaucoma
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Analysis of Autoantibodies Against Human Retinal Antigens in Sera of Patients with Glaucoma and Ocular Hypertension

2008

The aim of this study was to show that complex antibody patterns against retinal antigens in sera of patients with glaucoma, found in previous studies, are autoantibodies against human antigens.Sera of 179 patients were collected at the Department of Ophthalmology (University of Mainz, Germany): non-glaucomatous control patients (n=45), primary open-angle glaucoma (n=45), ocular hypertension (n=44), and normal tension glaucoma patients (n=45). The sera were tested against Western blots of human retinal antigens. IgG antibody patterns were analyzed by multivariate statistical techniques, and some significant antigens were identified by mass spectrometry.All subjects, even healthy ones, showe…

AdultMaleIntraocular pressuregenetic structuresBlotting WesternGlaucomaOcular hypertensionAutoantigensMass SpectrometryRetinaImmunoglobulin GHistonesTonometry OcularCellular and Molecular NeuroscienceAntigenNormal tension glaucomamedicineHumansIntraocular PressureAgedAutoantibodiesAged 80 and overArrestinbiologybusiness.industryAutoantibodyMiddle Agedmedicine.diseaseeye diseasesSensory SystemsOphthalmologyImmunoglobulin GImmunologybiology.proteinFemaleOcular HypertensionAntibodyCarrier ProteinsbusinessGlaucoma Open-AngleCurrent Eye Research
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Combined procedure for glaucoma and cataract: A retrospective study

1994

Abstract To ascertain the long-term effects of a triple procedure in the case of coexisting cataract and glaucoma, we did a retrospective study of 93 eyes that had cataract extraction, IOL implantation, and trabeculectomy within a ten-year period. Mean follow-up was 32.4 ± 21.9 months. Mean postoperative intraocular pressure (IOP) was significantly lower than preoperatively, even though fewer medications were being used. One year after surgery, 60% of eyes had a best corrected visual acuity of 20/40 or better with an average improvement of 3.8 Snellen lines. Patients who had had surgery four or more years before the study had the highest percentage of eyes with an IOP exceeding 22 mm Hg. Th…

AdultMaleIntraocular pressuremedicine.medical_specialtyAdolescentgenetic structuresmedicine.medical_treatmentEye diseaseVisual AcuityGlaucomaTrabeculectomyIntraocular lensCataract ExtractionOphthalmologymedicineHumansTrabeculectomyLongitudinal StudiesIntraocular PressureAgedRetrospective StudiesAged 80 and overLenses IntraocularBest corrected visual acuitybusiness.industryGlaucomaRetrospective cohort studyCombined procedureMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryOphthalmologyTreatment OutcomeFemaleSurgerysense organsbusinessFollow-Up StudiesJournal of Cataract and Refractive Surgery
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Prevalence of glaucoma and distribution of intraocular pressure in a population. The Casteldaccia Eye Study.

2009

IOP was measured in 1062 middle-aged and elderly subjects of a small Sicilian town, enrolled in a population based survey. The mean IOP was 15.1 +/- 3.7 mmHg without interocular or sex differences. A small but significant age-dependent increase of IOP was found. Circadian and seasonal influences were recorded: IOP was higher in the morning and in winter. The prevalence of chronic open-angle glaucoma was 1.2%, but it grew to 3.6 if only subjects aged 70 years or more were considered. IOP of 24 mmHg or more was found in 2.7%, while 4.3% of subjects showed IOP of 21 mmHg or more. This survey shows that mean IOP of the Mediterranean population studied is similar to the IOP found in other epidem…

AdultMaleIntraocular pressuremedicine.medical_specialtyAginggenetic structuresPopulationOcular hypertensionGlaucomaAge DistributionOphthalmologymedicinePrevalenceHumansCircadian rhythmSex DistributioneducationPopulation based surveySicilyIntraocular PressureMorningAgedAged 80 and overeducation.field_of_studybusiness.industryGlaucomaMiddle Agedmedicine.diseaseeye diseasesCircadian RhythmOphthalmologyAge distributionFemaleOcular Hypertensionsense organsSeasonsbusinessActa ophthalmologica Scandinavica
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Ocular pulse amplitude in patients with open angle glaucoma, normal tension glaucoma, and ocular hypertension.

2002

Intraocular pressure (IOP) is not a fixed constant value but rather has pulsatile components associated with cardiac action. The SmartLens dynamic observing tonometer (odc, Ophthalmic Development Company AG, Zurich, Switzerland) can measure and record simultaneously IOP and ocular pulse amplitude (OPA). It was the aim of this study to evaluate OPA in patients with primary open angle glaucoma (POAG) and high IOP, normal tension glaucoma (NTG), and ocular hypertension (OHT). Furthermore, the authors examined whether there were any correlations with blood pressure.80 subjects were divided into four groups (n=20): 20 patients each with POAG, NTG, and OHT and 20 volunteers without any ocular pat…

AdultMaleIntraocular pressuremedicine.medical_specialtyOpen angle glaucomagenetic structuresOcular PathologyOcular hypertensionGlaucomaBlood PressureCellular and Molecular NeuroscienceTonometry OcularOphthalmologyNormal tension glaucomaMedicineHumansIntraocular PressureAgedAged 80 and overbusiness.industryAge FactorsGlaucomaMiddle Agedmedicine.diseaseSensory Systemseye diseasesLow Tension GlaucomaOphthalmologyBlood pressureFemaleOcular Hypertensionsense organsbusinessGlaucoma Open-AngleScientific CorrespondenceThe British journal of ophthalmology
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Tolerability of 24-hour intraocular pressure monitoring of a pressure-sensitive contact lens.

2013

Purpose To investigate tolerability and safety of a new diagnostic device for 24-hour intraocular pressure monitoring in healthy subjects and age-matched glaucoma patients. Patients and methods Twenty healthy subjects (group 1) and 20 age-matched glaucoma patients (group 2) were included in this prospective, single-center, open, observational parallel group study. The SENSIMED Triggerfish Sensor is a soft disposable contact lens embedding a telemetry chip and strain gauge sensor for continuous intraocular pressure monitoring. The Sensor was placed in 1 eye for 24 hours. Tolerability was evaluated using a visual analog scale (range, 0 to 100; 0=no discomfort; 100=very severe discomfort). Saf…

AdultMaleIntraocular pressuremedicine.medical_specialtygenetic structuresCorneal PachymetryVisual analogue scaleVisual AcuityGlaucomaMonitoring AmbulatoryTonometry OcularOphthalmologyMedicineHumansTelemetryProspective StudiesCorneal pachymetryProspective cohort studyIntraocular PressureAgedmedicine.diagnostic_testEquipment Safetybusiness.industryCorneal TopographyGlaucomaMiddle Agedmedicine.diseaseCorneal topographyContact Lenses Hydrophiliceye diseasesCircadian RhythmContact lensOphthalmologyTolerabilityPatient SatisfactionFemalebusinessJournal of glaucoma
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Risk factors of ocular hypertension and glaucoma. The Casteldaccia Eye Study.

1994

A case-control study was planned as a part of the Casteldaccia Eye Study in order to investigate about risk factors of ocular hypertension and glaucoma. Cases were 44 subjects with glaucoma or intraocular pressure of 24 mm Hg or more. Controls were 220 subjects with intraocular pressure of 20 mm Hg or less and no signs of glaucoma. A number of environmental, behavioral, systemic and ocular variables were studied. Among the others we investigated the following: sunlight exposure, smoking, alcohol intake, pregnancies, systemic hypertension, diabetes, use of corticosteroids, refractive status, anterior chamber depth, lens nuclear sclerosis, iris color and texture. After univariate analysis the…

AdultMaleIntraocular pressuremedicine.medical_specialtygenetic structuresEye diseaseOcular hypertensionGlaucomaRisk FactorsPhysiology (medical)OphthalmologymedicineHumansRisk factorIntraocular PressureAgedAged 80 and overNuclear sclerosisbusiness.industryCase-control studyOdds ratioMiddle Agedmedicine.diseaseeye diseasesSensory SystemsOphthalmologyItalyCase-Control StudiesChronic DiseaseFemaleOcular Hypertensionsense organsbusinessGlaucoma Open-AngleDocumenta ophthalmologica. Advances in ophthalmology
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Falsely elevated intraocular pressure due to increased central corneal thickness

1999

PURPOSE: To evaluate whether ocular hypertensive subjects have a higher central corneal thickness than other individuals. METHODS: In this prospective study, 48 subjects with ocular hypertension, 63 patients with open-angle glaucoma, 56 nonglaucomatous patients with diabetes mellitus, and 106 control subjects were evaluated. Corneal thickness was measured by ultrasound pachymetry, and intraocular pressure was determined by Goldmann applanation tonometry. RESULTS: Central corneal thickness was significantly higher in the ocular hypertensive subjects, mean +/- S.D., 592+/-39 microm, than in the patients with glaucoma (536+/-34 microm), the nonglaucomatous patients with diabetes mellitus (550+…

AdultMaleIntraocular pressuremedicine.medical_specialtyprimary open-angle glaucomaAdolescentgenetic structuresEye diseaseOcular hypertensionGlaucomaCorneaCellular and Molecular NeurosciencePredictive Value of TestsCorneaOphthalmologyDiabetes mellitusHumansMedicineFalse Positive ReactionsProspective StudiesCorneal pachymetry[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory OrgansProspective cohort studyAgedUltrasonographyAged 80 and overmedicine.diagnostic_testdiabetesbusiness.industryMiddle Agedmedicine.diseaseSensory Systemseye diseasesSurgeryOphthalmologymedicine.anatomical_structureocular hypertensionFemalecentral corneal thicknesssense organsbusinessGlaucoma Open-Angle[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyintraocular pressure
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Intrastromal corneal ring segment implantation in paracentral keratoconus with coincident topographic and coma axis.

2012

To evaluate the efficacy, predictability, and safety of implantation of Ferrara-type intrastromal corneal ring segments (ICRS) for refractive correction of paracentral keratoconus.Fernández-Vega Ophthalmological Institute, Oviedo, Spain.Cohort study.Snellen uncorrected (UDVA) and corrected (CDVA) distance visual acuities and residual refractive errors were recorded before and 6 months after ICRS implantation for keratoconus. The tunnels for ICRS implantation were created with a femtosecond laser. The power vector and the Alpins method were used to analyze postoperative refractive outcomes.The study evaluated 56 eyes of 49 patients. The mean UDVA was 0.17 ± 0.14 (SD) preoperatively and 0.41 …

AdultMaleKeratoconusmedicine.medical_specialtygenetic structuresmedicine.medical_treatmentCorneal StromaVision DisordersVisual AcuityComa (optics)Power vectorKeratoconusRefraction OcularCohort StudiesProsthesis ImplantationYoung AdultOphthalmologymedicineHumansPolymethyl MethacrylateProspective StudiesAlpins methodAgedIntrastromal corneal ring segmentbusiness.industryCorneal TopographyProstheses and ImplantsMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryOphthalmologySurgeryFemalesense organsLaser TherapyCorneal ringbusinessJournal of cataract and refractive surgery
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Translocation (X;18) in a Biphasic Synovial Sarcoma with Morphologic Features of Neural Differentiation

1998

The authors report a recurred neoplasm showing distinctive histologic, immunophenotypic, and ultrastructural features characteristic of biphasic synovial sarcoma with neural differentiation. The features include areas with a growth pattern of densely packed spindle cells in irregularly intersecting, broad fascicles, diffuse vimentin and HBA 71 immunoreactivity, expression of S-100 protein, and other neural markers. Moreover, areas with glandular structures and cellular expression of cytokeratin and epithelial membrane antigen were noted. Additionally, areas of neural-like growth pattern were positive for neuron-specific enolase, HNK-1, and protein gene product 9.5. Furthermore, cytogenetic …

AdultMaleLung NeoplasmsX ChromosomeBiphasic Synovial SarcomaEnolaseSoft Tissue NeoplasmsChromosomal translocationVimentinPolymerase Chain ReactionTranslocation GeneticImmunophenotypingPathology and Forensic MedicineGene productSarcoma SynovialCytokeratinTumor Cells CulturedmedicineHumansMolecular BiologyIn Situ Hybridization FluorescenceNeuronsmedicine.diagnostic_testbiologyChemistryCell DifferentiationPatellaCell BiologyMolecular biologyReverse transcription polymerase chain reactionKaryotypingbiology.proteinChromosomes Human Pair 18Fluorescence in situ hybridizationDiagnostic Molecular Pathology
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