Search results for "Coma"

showing 10 items of 1084 documents

Congenital dermatofibrosarcoma protuberans: 30 years of follow-up

2007

Summary Dermatofibrosarcoma protuberans (DFSP) is a rare fibrohistiocytic tumor that commonly appears in adult patients. Few cases of DFSP in childhood have been reported. We describe a case of congenital DFSP that had been incompletely excised in childhood, and again at 28 years of age. The 33-year-old woman presented with a recurrence. When comparing the histologic features of the previous specimens excised in 1970 and 30 years later, the similar typical storiform pattern of fibromatous cells was found. The small number of proliferation-marker-positive cells was not altered over the course of 30 years. In line with a few additional reports, we suggest that congenital dermatofibrosarcoma p…

Adultmedicine.medical_specialtySkin NeoplasmsAdult patientsbusiness.industryDermatofibrosarcomaDermatologyFibrohistiocytic tumormedicine.diseaseDermatologyChild PreschoolDermatofibrosarcoma protuberansmedicineHumansFemaleNeoplasm Recurrence LocalbusinessFollow-Up StudiesJDDG
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Dermoscopic characteristics of a cutaneous histiocytic sarcoma in a young patient

2017

Adultmedicine.medical_specialtySkin Neoplasmsbusiness.industryJuvenile xanthogranulomaBreast NeoplasmsDermoscopyDermatologyHistiocytic sarcomamedicine.diseaseDermatology030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisHumansMedicineFemaleHistiocytic SarcomabusinessHistiocyteJournal of the American Academy of Dermatology
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Ballon occlusion of the renal artery in tumor nephrectomy.

1975

AbstractA method of preoperative intraluminal occlusion of the renal artery in cases of kidney tumors using a 5F Swan-Ganz balloon catheter is presented. The procedure was used in 26 tumor nephrectomies without complications and resulted in marked facilitation of the operation in 70 per cent of the cases.

Adultmedicine.medical_specialtyTime FactorsUrologymedicine.medical_treatmentHemorrhageAdenocarcinomaNephrectomyCatheterizationNeoplasm SeedingRenal Arterymedicine.arteryOcclusionmedicineHumansRenal arteryAgedKidneybusiness.industryCarcinomaBalloon catheterSarcomaMiddle AgedNephrectomyKidney NeoplasmsSurgerymedicine.anatomical_structureBalloon occlusionRadiologybusinessThe Journal of urology
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Learning Curve and Fatigue Effect of Flicker Defined Form Perimetry

2011

To evaluate the learning curve and fatigue effect of flicker defined form (FDF) perimetry.Prospective cross-sectional study.One hundred forty-one eyes of 75 healthy subjects were included in the study. Every subject was measured 3 times on 3 different days within 3 months. Differences among the tests were analyzed for mean sensitivity (MS), mean deviation (MD), pattern standard deviation (PSD), reliability indices, test duration, and test points5% and0.5% in 75 right eyes on the basis of linear mixed models for repeated measurements. To assess the effect of fatigue, differences of MS, MD, and PSD values between 66 left and right eyes were evaluated regarding alterations between these 3 exam…

Adultmedicine.medical_specialtyVisual AcuitySignificant learningSensitivity and SpecificityPattern standard deviationOphthalmologymedicineHumansProspective StudiesIntraocular PressureAgedbusiness.industryFlickerHealthy subjectsGlaucomaMiddle AgedTest durationAbsolute deviationOphthalmologyCross-Sectional StudiesVisual Field TestsAsthenopiaVisual FieldsbusinessLearning CurveAmerican Journal of Ophthalmology
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Peritoneal sarcomatosis 5 years after laparoscopic morcellation of uterine leiomyoma.

2017

In 2011, a 40-year-old woman underwent laparoscopic myomectomy with intraabdominal morcellation. Histology report showed leiomyoma without atypia, necrosis, or mitosis. In 2016, she complained of left lower quadrant pain; ultrasound examination revealed a left hypogastric mass in the site of trocar placement. Percutaneous biopsy results showed a low-grade endometrial stromal sarcoma (LGESS). At laparoscopy, we observed: multiple nodules on uterine serosa, left annex, vesical peritoneum (Figure 1), Douglas pouch (Supplementary Video1), previous left pelvic trocar site (Figure 2), greater omentum (Figure 3), and right/left diaphragm.

Adultmedicine.medical_specialtymedicine.medical_treatmentSarcoma Endometrial StromalMorcellationAnastomosisHysterectomyDouglas' Pouch03 medical and health sciences0302 clinical medicineUterine MyomectomyUterine NeoplasmmedicineHumansEndometrial Neoplasm030212 general & internal medicinePeritoneal Neoplasms030219 obstetrics & reproductive medicineUterine leiomyomaHysterectomyLeiomyomabusiness.industryAnastomosis SurgicalRectumObstetrics and GynecologySarcomatosismedicine.diseaseUterine myomectomySurgeryEndometrial NeoplasmsCell Transformation NeoplasticUterine NeoplasmsFemaleSarcomabusinessPeritoneal NeoplasmOmentumHumanAmerican journal of obstetrics and gynecology
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Combined therapy with acyclovir and adenosine arabinoside in herpes simplex encephalitis.

1987

We report a case of herpes simplex encephalitis (HSE) with initial coma and severe left-sided hemiparesis in which combined treatment with adenine arabinoside and acyclovir was followed by complete recovery. This favorable result is discussed in view of the literature of HSE treatment including experimental studies on antiviral activity of both drugs. Combined treatment may be useful in severe cases of HSE.

Adultmedicine.medical_treatmentAcyclovirmedicineHumansAciclovirVidarabineComaChemotherapybusiness.industryHerpes Simplexmedicine.diseaseVirologyAdenosineHemiparesisNeurologyEncephalitisDrug Therapy CombinationFemaleNeurology (clinical)Viral diseasemedicine.symptombusinessTomography X-Ray ComputedEncephalitisVidarabinemedicine.drugEuropean neurology
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Mitochondrial Markers in Aging and Primary Open-Angle Glaucoma

2020

This review focuses on recent progress in understanding the role of mitochondrial markers in the context of mitochondrial dysfunction in glaucoma and discussing new therapeutic approaches to modulate mitochondrial function and potentially lead to improved outcomes in glaucoma.

AgingMitochondrial Diseasesgenetic structuresOpen angle glaucomabusiness.industryGlaucomaContext (language use)medicine.diseaseBioinformaticseye diseasesOphthalmologyRetinal DiseasesmedicineHumanssense organsbusinessBiomarkersGlaucoma Open-AngleJournal of Glaucoma
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Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

2015

Primary open-angle glaucoma is the most common optic neuropathy and an important cause of irreversible blindness worldwide. The optic nerve head or optic disc is divided in two parts: a central cup (without nerve fibers) surrounded by the neuroretinal rim (containing axons of the retinal ganglion cells). The International Glaucoma Genetics Consortium conducted a meta-analysis of genome-wide association studies consisting of 17,248 individuals of European ancestry and 6,841 individuals of Asian ancestry. The outcomes of the genome-wide association studies were disc area and cup area. These specific measurements describe optic nerve morphology in another way than the vertical cup-disc ratio, …

Aginggenetic structuresEpidemiologyOptic diskGlaucomaGenome-wide association studyNeurodegenerativeEyeOptic neuropathyOptic Nerve DiseasesNERVEGWASGenetics (clinical)GeneticsNEIGHBORHOOD ConsortiumATOH7Asiansmedicine.anatomical_structurecup areaOptic nervePublic Health and Health ServicesOPEN-ANGLE GLAUCOMATRAITSOptic discAsian Continental Ancestry Groupmedicine.medical_specialtyOpen angle glaucomaEuropean Continental Ancestry GroupOptic DiskQuantitative Trait LociBiologyOCULAR-TISSUESRetinal ganglionArticleWhite PeopleAsian PeopleOphthalmologymedicineGeneticsHumansdisc areaEye Disease and Disorders of VisionWhitesHuman GenomeNeurosciencesGlaucomaGENOTYPESmedicine.diseaseGENEeye diseasesSIZEglaucomasense organsGenome-Wide Association Study
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Receptor Activator of NF-kB (RANK) Expression in Primary Tumors Associates with Bone Metastasis Occurrence in Breast Cancer Patients

2011

Background\ud Receptor activator of NFkB (RANK), its ligand (RANKL) and the decoy receptor of RANKL (osteoprotegerin, OPG) play a pivotal role in bone remodeling by regulating osteoclasts formation and activity. RANKL stimulates migration of RANK-expressing tumor cells in vitro, conversely inhibited by OPG.\ud \ud Materials and Methods\ud We examined mRNA expression levels of RANKL/RANK/OPG in a publicly available microarray dataset of 295 primary breast cancer patients. We next analyzed RANK expression by immunohistochemistry in an independent series of 93 primary breast cancer specimens and investigated a possible association with clinicopathological parameters, bone recurrence and surviv…

Anatomy and PhysiologyMicroarraysSettore MED/06 - Oncologia MedicaCancer TreatmentLigandsMetastasisBone remodelingMetastasisBasic Cancer ResearchBreast TumorsBone and Soft Tissue SarcomasNeoplasm MetastasisMusculoskeletal SystemOligonucleotide Array Sequence AnalysisMultidisciplinaryPredictive markerReceptor Activator of Nuclear Factor-kappa BQRBone metastasisMiddle AgedImmunohistochemistryGene Expression Regulation NeoplasticOncologyRANKLMedicineFemaleResearch Articlemusculoskeletal diseasesmedicine.medical_specialtyHistologyScienceBone NeoplasmsBreast NeoplasmsBiologyBreast cancerAntibody TherapySDG 3 - Good Health and Well-beingOsteoprotegerinInternal medicinemedicineHumansRNA MessengerBoneBiologyAgedBreast cancer bone metastasis RANK-RANKLRANK LigandOsteoprotegerinComputational BiologyCancers and NeoplasmsRANK Ligandmedicine.diseaseEndocrinologyCancer researchbiology.protein
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E' lo stress fattore di rischio per il glaucoma primario ad angolo aperto?

2011

Ansia Campo visivo Glaucoma cronico ad angolo apertoGDx VVC Stress
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