Search results for "Coma"

showing 10 items of 1084 documents

Biological tolerance of different materials in bulk and nanoparticulate form in a rat model: sarcoma development by nanoparticles

2006

In order to study the pathobiological impact of the nanometre-scale of materials, we evaluated the effects of five different materials as nanoparticulate biomaterials in comparison with bulk samples in contact with living tissues. Five groups out of 10 rats were implanted bilaterally for up to 12 months with materials of the same type, namely TiO 2 , SiO 2 , Ni, Co and polyvinyl chloride (PVC), subcutaneously with bulk material on one side of the vertebral column and intramuscularly with nanoparticulate material on the contralateral side. At the end of each implantation time, the site was macroscopically examined, followed by histological processing according to standard techniques. Malign…

Skin NeoplasmsSilicon dioxideBiological; tolerance; different; materials; bulk; nanoparticulate; rat model; sarcoma; development; nanoparticlesRat modelBiomedical EngineeringBiophysicsNanoparticleMetal NanoparticlesBioengineeringBiocompatible MaterialsBiochemistryPreneoplastic lesionBiomaterialschemistry.chemical_compoundNickelBulk samplesMaterials TestingmedicineAnimalsPolyvinyl ChlorideTitaniumSarcomaCobaltmedicine.diseaseSilicon DioxideRatsPolyvinyl chloridechemistrySarcomaImplantation timeBiotechnologyBiomedical engineeringResearch Article
researchProduct

Gynecomastia

2020

Gynecomastia is a swelling of the male breast as a result of the growth of two components: The adipose and the glandular tissue, sometimes unilateral, but more often occurring in bilateral form. Several classification systems were proposed, based on the hypertrophy of the tissue and the position of the nipple-areola complex. The clinical examination and blood analysis play an important role in excluding endocrine tumors or hormone balance modification and in choosing the treatment. The management of gynecomastia considers the drug therapy in case of hormones disorder. But surgical procedures, such as the combined adenectomy/liposuction, represent the gold standard of treatment. Skin redunda…

Skin redundancyPectoralis major muscleSettore MED/19 - Chirurgia PlasticaGynecomastiaMammoplasties
researchProduct

Porous titania surfaces on titanium with hierarchical macro- and mesoporosities for enhancing cell adhesion, proliferation and mineralization

2014

Titanium received a macroporous titania surface layer by anodization, which contains open pores with average pore diameter around 5 μm. An additional mesoporous titania top layer following the contour of the macropores, of 100-200 nm thickness and with a pore diameter of 10nm, was formed by using the evaporation-induced self-assembly (EISA) method with titanium (IV) tetraethoxide as the precursor. A coherent laminar titania surface layer was thus obtained, creating a hierarchical macro- and mesoporous surface that was characterized by high-resolution electron microscopy. The interfacial bonding between the surface layers and the titanium matrix was characterized by the scratch test that con…

Solid-state chemistryMaterials scienceSurface Propertieschemistry.chemical_elementBone NeoplasmsBioengineeringNanotechnologyMineralization (biology)BiomaterialsCalcification PhysiologicCell Line TumorCell AdhesionHumansSurface layerPorosityCell ProliferationTitaniumOsteosarcomaAnodizingTitanium oxideChemical engineeringchemistryMechanics of MaterialsMicroscopy Electron ScanningPorosityLayer (electronics)TitaniumMaterials Science and Engineering: C
researchProduct

Note brevi a margine della proposta di riforma dei reati ambientali del gruppo di studio dell'associazione dei professori di diritto penale

2022

A partire dall’analisi della proposta di riforma dei reati contro l’ambiente elaborata dal Gruppo di studio dell’Associazione italiana dei Professori di Diritto Penale, il contributo riflette sui principali problemi teorici del diritto penale ambientale (tipizzazione dell’evento lesivo nelle fattispecie di inquinamento e di disastro ambientale, imputazione soggettiva dei delitti aggravati dall’evento, contrasto penale alle c.d. “ecomafie” nel settore dei rifiuti ecc.), mettendo a confronto le soluzioni suggerite nel testo con le prospettive di riforma contenute nella recente Proposta di Direttiva del Parlamento europeo e del Consiglio sulla Protezione dell’ambiente at- traverso il diritto p…

Starting from the analysis of the proposal for the reform of crimes against the environment drawn up by the Study Group of the Italian Association of Professors of Criminal Law the paper reflects on the main theoretical problems of environmental criminal law (typification of the event in pollution crime and environmental disaster crime mental element of crimes aggravated by the event fight to the so-called “ecomafie” in the waste sector etc.) comparing the solutions suggested in the text with the recent Proposal for a Directive of the European Parliament and of the Council on the Protection of the Environment through Criminal Law that replaces Directive 2008/99.Settore IUS/17 - Diritto Penale
researchProduct

Pyrrolo[2,3-h]quinolinones: synthesis and photochemotherapic activity.

2003

A series of derivatives of the new ring system pyrrolo[2,3-h]quinoline-2-one was synthesized and evaluated as photoreagents toward cultured human tumor cells. Remarkable phototoxycity resulted for some derivatives, especially those bearing the phenyl group at the 7-position.

StereochemistryFibrosarcomaClinical BiochemistryPharmaceutical ScienceAntineoplastic AgentsQuinolonesRing (chemistry)BiochemistryChemical synthesischemistry.chemical_compoundStructure-Activity RelationshipDrug DiscoveryTumor Cells CulturedPhenyl groupHumansPhotosensitizerPyrrolesMolecular BiologyPhotosensitizing AgentsChemistryOrganic ChemistryGeneral MedicineIn vitroHuman tumorPhotochemotherapyCell cultureLactamMolecular MedicineDrug Screening Assays AntitumorBioorganicmedicinal chemistry letters
researchProduct

Isolated osteoblastoma of the cuboid bone: A case report and review of the literature

2020

Osteoblastoma is a relatively rare, benign, bone-forming tumor, commonly observed in the second and third decades of life. Spine and the long tubular bones are the most common sites of involvement. Osteoblastoma is infrequently seen in other sites, including the bones of hand and foot. A rare case of a 35-year-old man that presented an osteoblastoma of the cuboid bone is reported. The patient was treated with surgical resection and grafting. After the intervention, the patient recovered with no clinical and radiological evidence of recurrence after one year of follow-up. Several cases of osteoblastoma-like variant of osteosarcoma of the cuboid have been previously reported, but, to our know…

Surgical resectionAdultMalemedicine.medical_specialtyPainBone Neoplasms03 medical and health sciencesBone-formin0302 clinical medicineOsteoblastomaCuboid boneRare caseBone tumorsPathologyMedicineHumansOrthopedics and Sports MedicineOsteoblastomaPodiatryMidfootBone tumor030203 arthritis & rheumatologyCuboidBone tumors; Bone-forming; Midfoot; Pain; Pathology; Rare disease.business.industry030229 sport sciencesTarsal Bonesmedicine.diseaseMidfoot PathologyBone-formingOsteosarcomaBone formingRadiologybusinessRare diseaseRare disease
researchProduct

Cataratta e glaucoma: cosa cambia nella chirurgia della cataratta ? E in quella del glaucoma ?

2008

TIMING CHIRURGICOTIMINGSettore MED/30 - Malattie Apparato VisivoCHIRURGIA CATARATTACHIRURGIA DEL GLAUCOMACHIRURGIA DELLA CATARATTACHIRURGIA GLAUCOMA
researchProduct

Effect of an oral supplementation with a formula containing R-lipoic acid in glaucoma patients

2020

Abstract Objective To analyse the safety and effectiveness of the oral administration of a commercialised supplement containing R-alpha lipoic acid (ALA), taurine, vitamins C and E, lutein, zeaxanthin, zinc, copper and docosahexaenoic acid (DHA), in patients with primary open angle glaucoma (POAG), and in control subjects. Material and methods A prospective study of cases and controls was carried out, including 30 participants of both genders that were divided into: POAG Group (n = 15) and a control group (CG; n = 15), assigned to the oral intake of NuaDHA preparations Vision® (1 pill/day) + NuaDHA 1000 (2 pills/day) for 6 months. Participants were interviewed, ophthalmologically examined, …

Taurinemedicine.medical_specialtygenetic structuresbusiness.industryGlaucomaGeneral MedicineMalondialdehydemedicine.diseaseGastroenterologyeye diseaseschemistry.chemical_compoundLipoic acidchemistryIntolerancesOral administrationDocosahexaenoic acidInternal medicinemedicinebusinessProspective cohort studyArchivos de la Sociedad Española de Oftalmología (English Edition)
researchProduct

Effect of the applied organic load rate on biodegradable polymer production by mixed microbial cultures in a Sequencing Batch Reactor

2006

This article studies the operation of a new process for the production of biopolymers (polyhydroxyalkanoates, PHAs) at different applied organic load rates (OLRs). The process is based on the aerobic enrichment of activated sludge to obtain mixed cultures able to store PHAs at high rates and yields. A mixture of acetic, lactic, and propionic acids at different concentrations (in the range 8.5-31.25 gCOD/L) was fed every 2 h in a sequencing batch reactor (SBR). The resulting applied OLR was in the range 8.5-31.25 gCOD/L/day. Even though, as expected, the increase in the OLR caused an increase in biomass concentration (up to about 8.7 g COD/L), it also caused a relevant decrease of maximal po…

ThaueraPolyestersSEQUENCING BATCH REACTORPROCESS CONTROLPOLYHYDROXYALKANOATESBioengineeringSequencing batch reactorMICROBIAL STORAGE POLYMERSSEQUENCING BATCH REACTOR; POLYHYDROXYALKANOATES; MICROBIAL STORAGE POLYMERS; MICROBIAL CENOSIS CHARACTERISATION; FAMINE CONDITIONS; PROCESS CONTROLApplied Microbiology and BiotechnologyWaste Disposal FluidPolyhydroxyalkanoatesWater PurificationBiopolymersBioreactorsBioreactorFood scienceBiomassFAMINE CONDITIONSComamonasbiologyBacteriaMICROBIAL CENOSIS CHARACTERISATIONbusiness.industryChemistryBiodegradationbiology.organism_classificationBiotechnologyActivated sludgeAcids AcyclicAlcaligenesbusinessBiotechnology
researchProduct

Pulmonary artery sarcoma mimicking chronic thromboembolic disease: computed tomography and magnetic resonance imaging findings.

1994

The diagnosis of the rare primary malignant tumors of the pulmonary arteries is often delayed as symptoms are nonspecific.Computed tomography (CT) and magnetic resonance imaging (MRI) of three patients with occlusion of the right pulmonary artery, two with sarcoma and one with chronic thromboembolic disease were analyzed for discriminating diagnostic criteria.Criteria suggesting pulmonary artery sarcoma are inhomogeneous high or low attenuation (hemorrhage, necrosis), soft-tissue density in pulmonary arteries, vascular distension, enhancement after administration of gadopentetate dimeglumine. Criteria for chronic thromboembolic disease are homogeneous soft-tissue lesions, abrupt vascular na…

ThoraxAdultMalemedicine.medical_specialtyPathologyPulmonary ArteryDiagnosis Differentialmedicine.arteryMedicineHumansRadiology Nuclear Medicine and imagingVascular Diseasesmedicine.diagnostic_testbusiness.industryUltrasoundRespiratory diseaseMagnetic resonance imagingSarcomaMiddle Agedmedicine.diseaseMagnetic Resonance ImagingPulmonary embolismPulmonary arteryFemaleRadiologySarcomaDifferential diagnosisCardiology and Cardiovascular MedicinebusinessPulmonary EmbolismTomography X-Ray ComputedCardiovascular and interventional radiology
researchProduct