Search results for "Coma"
showing 10 items of 1084 documents
Glaucomatous Maculopathy: Thickness Differences on Inner and Outer Macular Layers between Ocular Hypertension and Early Primary Open-Angle Glaucoma U…
2020
The purpose of this study was to compare the thickness of all inner and outer macular layers between ocular hypertension (OHT) and early primary open-angle glaucoma (POAG) using spectral domain optical coherence tomography (SD-OCT) 8 × 8 posterior pole algorithm (8 × 8 PPA). Fifty-seven eyes of 57 OHT individuals and fifty-seven eyes of 57 early POAG patients were included. The thickness of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform and nuclear layer, photoreceptor layer (PRL) and retinal pigment epithelium were obtained in 64 cells for each macular layer and mean thickness of superior and inf…
From the forest to the plate – Hemicelluloses, galactoglucomannan, glucuronoxylan, and phenolic-rich extracts from unconventional sources as function…
2021
This study aimed to characterise pressurised hot water (PHW) extracts from nonconventional sources of functional carbohydrates and phenolic compounds in terms of antioxidant capacity, antiviral activity, toxicity, and human erythrocytes’ protection antidiabetic potential. PHW extracts of Norway spruce bark (E1 + E2) and Birch sawdust (E3 + E4) contained mostly galactoglucomannan and glucuronoxylan. In contrast, samples E5 to E9 PHW extracted from Norway spruce, and Scots pine bark are rich sources of phenolic compounds. Overall, phenolic-rich extracts presented the highest inhibition of α-amylase and α-glucosidase and protection against stable non-enveloped enteroviruses. Additionally, all …
Modificación de la histéresis corneal y su influencia en la cirugía de glaucoma y en la biomecánica del nervio óptico
2013
El principal factor de riesgo para el desarrollo de la neuropatía óptica glaucomatosa y el único en el que podemos actuar hoy en día es la elevación de la presión intraocular, por lo que cobra extrema importancia la exquisitez en la determinación del parámetro en el que va a girar nuestra actitud. Sin embargo, existen múltiples situaciones donde los pacientes, a pesar de tener la PIO en límites normales, continúan progresando. Se han apuntado múltiples causas para este fenómeno como la fluctuación de la PIO o el aumento nocturno de la PIO por el decúbito supino; pero la aparición del concepto de histéresis ocular planteó nuevos interrogantes desde 2 puntos de vista principalmente. El primer…
The Neoplastic Side of the Abdominal Wall: A Comprehensive Pictorial Essay of Benign and Malignant Neoplasms
2023
Abdominal wall neoplasms are usually benign and, in the majority of these cases, no further work-up or treatment is indicated. The percentage of malignant abdominal neoplasms, however, is not negligible. Radiologists play a pivotal role in identifying imaging features that should favor malignancy, including larger lesion size, edema, neurovascular involvement, and peripheral or inhomogeneous dynamic enhancement, thus indicating to the clinician the need for further work-up. Histopathology is the reference standard for the characterization of abdominal wall neoplasms. In patients undergoing surgery, radiological assessment is needed to guide the surgeon by providing a comprehensive anatomic …
Tumour oxygenation during fractionated radiotherapy--comparison with size-matched controls.
1999
The effect of fractionated irradiation on the oxygenation status of experimental tumours was investigated using polarographic assessment of the pO2 distribution. Since an improvement in tumour oxygenation could simply be the result of tumour shrinkage, a comparison of pO2 readings of untreated size-matched control tumours was performed. Irradiation was carried out using 6 fractions of 6 Gy applied within 11 days. A comparison of polarographic pO2 data with size-matched untreated tumours revealed a significant improvement in oxygenation after the irradiation. The median pO2 was 0.9+/-0.1 mm Hg for unirradiated tumours at a volume of 180 mm3, while the corresponding data for irradiated tumour…
Prognostic Relevance of CCN3 in Bone Sarcomas
2010
Osteosarcomas and Ewing’s sarcoma (EWS) are aggressive malignant bone tumors. In both cases, prognostic markers are lacking. Presently, only clinical features are widely accepted as prognostic indicators. In this study we assessed the prognostic value of CCN3 (Nov), a matricellular protein that belong to the CCN family of regulatory proteins, whose members were shown to play crucial roles in bone formation. In osteosarcomas, CCN3 expression levels represent a useful tool to early identification of patients with different prognosis. In both osteosarcomas and Ewing’s sarcomas, the expression of a full length CCN3 protein was associated to a worse prognostic and a higher risk to developing met…
Karaistumisen ja lisääntymisdiapaussin vaikutukset Drosophila montana -mahlakärpästen kylmänkestävyyteen
2011
Kylmyys on yksi tärkeimmistä lajien levinneisyyteen ja runsauteen vaikuttavista stressitekijöistä. Karaistuminen ja lisääntymisdiapaussi ovat esimerkkejä hyönteisten fysiologisesta ja biokemiallisesta sopeutumista mataliin lämpötiloihin. Karaistumisella tarkoitetaan lyhyen ajan sisällä tapahtuvaa kylmänkestävyyden kasvamista, ja sillä voi olla huomattava vaikutus kylmistä olosuhteista selviytymiseen. Lisääntymisdiapaussin laukaisee ympäristöstä tulevat ärsykkeet, kuten muutokset päivän pituudessa ja lämpötilassa. Se parantaa naaraiden mahdollisuuksia selvitä epäedullisista vuodenajoista ja siirtää jälkeläisten tuoton ajankohtaan jolloin munien ja jälkeläisten selviytyminen on parhaimmillaan…
Serological Levels of Anti-clathrin Antibodies Are Decreased in Patients With Pseudoexfoliation Glaucoma
2021
Evidence for immunologic contribution to glaucoma pathophysiology is steadily increasing in ophthalmic research. Particularly, an altered abundance of circulating autoantibodies to ocular antigens is frequently observed. Here, we report an analysis of autoantibody abundancies to selected antigens in sera of open-angle glaucoma patients, subdivided into normal-tension glaucoma (N = 31), primary open-angle glaucoma (N = 43) and pseudoexfoliation glaucoma (N = 45), vs. a non-glaucomatous control group (N = 46). Serum samples were analyzed by protein microarray, including 38 antigens. Differences in antibody levels were assessed by ANOVA. Five serological antibodies showed significantly altered…
Autoantigens in the trabecular meshwork and glaucoma‐specific alterations in the natural autoantibody repertoire
2019
Abstract Objectives Primary open‐angle glaucoma (POAG) is a neurodegenerative disorder leading to a gradual vision loss caused by progressive damage to the optic nerve. Immunological processes are proposed to be involved in POAG pathogenesis. Altered serological autoantibody levels have been frequently reported, but complete analyses of the natural autoantibodies with respect to disease‐related alterations are scarce. Here, we provide an explorative analysis of pathways and biological processes that may involve naturally immunogenic proteins and highlight POAG‐specific alterations. Methods Mass spectrometry‐based antibody‐mediated identification of autoantigens (MS‐AMIDA) was carried out in…
La poesia catalana i el boom de l'any 1972
2021
The year of 1972 is a very important date in the understanding of the evolution of Catalan poetry, during the decade of the 70's. The changes in this year make up the basic framework for the future characterization of the genre. The article aims to establish a syncronized break away from the year previously mentioned to choose the objective facts that this break demonstrates and interpret them in order to show the repercussion of all. There are four basic elements: the death of Gabriel Ferrater; the publication of three fundamental poetry books by significant poets (Pere Gimferrer, Narcís Comadira and Francesc Parcerisas); the appearance of new names like Xavier Bru de Sala or Ramon Pinyol,…