Search results for "Compromis"
showing 10 items of 397 documents
Antifungal agents for preventing fungal infections in non-neutropenic critically ill patients
2016
Background Invasive fungal infections are important causes of morbidity and mortality among critically ill patients. Early institution of antifungal therapy is pivotal for mortality reduction. Starting a targeted antifungal therapy after culture positivity and fungi identification requires a long time. Therefore, alternative strategies (globally defined as 'untargeted antifungal treatments') for antifungal therapy institution in patients without proven microbiological evidence of fungal infections have been discussed by international guidelines. This review was originally published in 2006 and updated in 2016. This updated review provides additional evidence for the clinician dealing with s…
Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease
2014
The treatment of inflammatory bowel disease (IBD) has been revolutionised over the past decade by the increasing use of immunomodulators, mainly azathioprine (AZA)/6-mercaptopurine (6-MP) and methotrexate (MTX), together with the advent of biological therapy. Immunomodulators are being used more often and earlier in the course of the disease.1 The introduction of biologic agents, especially inhibitors of the key proinflammatory cytokine, tumor necrosis factor alpha (TNF-α) initiated a new therapeutic era, whose use has grown continuously since their introduction in 1998.2 With such immunomodulation, the potential for opportunistic infection is a key safety concern for patients with IBD. Opp…
COVID-19 Vaccination in Pregnancy, Paediatrics, Immunocompromised Patients, and Persons with History of Allergy or Prior SARS-CoV-2 Infection: Overvi…
2021
To date, four vaccines have been authorised for emergency use and under conditional approval by the European Medicines Agency to prevent COVID-19: Comirnaty, COVID-19 Vaccine Janssen, Spikevax (previously COVID-19 Vaccine Moderna) and Vaxzevria (previously COVID-19 Vaccine AstraZeneca). Although the benefit–risk profile of these vaccines was proven to be largely favourable in the general population, evidence in special cohorts initially excluded from the pivotal trials, such as pregnant and breastfeeding women, children/adolescents, immunocompromised people and persons with a history of allergy or previous SARS-CoV-2 infection, is still limited. In this narrative review, we critically overv…
Nephrotoxicity in the setting of invasive fungal diseases
2008
Amphotericin B, a broad spectrum antifungal agent, is widely used despite significant adverse events including nephrotoxicity. Nephrotoxicity occurs frequently in patients receiving amphotericin B. Different definitions for nephrotoxicity are reviewed in the context of outcome in patients with invasive fungal diseases. In most publications, mortality was higher in patients experiencing nephrotoxicity and mean hospital length of stay was prolonged. As a consequence, the use of less nephrotoxic antifungal agents could improve treatment outcomes.
Presence of potentially pathogenic free-living amoebae strains from well water samples in Guinea-Bissau
2014
Free-living amoebae (FLA) include opportunistic pathogens such as Naegleria fowleri, Balamuthia mandrillaris, and the genera Sappinia and Acanthamoeba. In this study, a survey was conducted in order to evaluate the presence of potentially pathogenic amoebic strains in water samples collected from wells located in the western part of Guinea-Bissau. The samples were left to precipitate for 48 hours and then the sediments were seeded on non-nutrient agar plates containing Escherichia coli spread and cultures were checked daily for the presence of FLA. Identification of FLA strains was based on the morphological and polymerase chain reaction (PCR) using the 18S rDNA or 16S mitochondrial rDNA ge…
La medición de la felicidad en el trabajo y sus antecedentes : un estudio empírico en el area de alergología de los hospitales públicos españoles
2014
La búsqueda de la felicidad en el trabajo es un objetivo de enorme importancia para muchas personas y organizaciones. Sin embargo, existe una carencia importante la investigación acerca de cómo aumentarla (Chivato Pérez et al., 2011), así como una amplia dispersión de medidas relacionadas (Hackman, 2009). No se conoce ninguna medida que recoja con la suficiente amplitud la medición de la felicidad en el trabajo (Fisher, 2010), por lo que en este estudio proponemos un modelo integrativo que nos aporte la medida de este nuevo constructo. Proponemos que la felicidad en el trabajo se compone de tres constructos ya consolidados en la literatura. La primera hipótesis de esta investigación es que …
La surprenante disqualification de la clause compromissoire optionnelle bilatérale
2022
(Paris 1er juill. 2021, no 21/01799, RDC 2021. 51, note M. Laazouzi)
L'assureur peut-il opposer à la victime, qui exerce l'action directe contre l'assureur de l'auteur du dommage, la clause compromissoire contenue dans…
2022
(Versailles 21 janv. 2021, no 19/02675, SAS Rohlig France c/ Sté Vincy Construction Grands Projet, Rev. arb. 2021. 844, note J. Billemont)
L'article 48 du code de procédure civile est inapplicable aux clauses d'arbitrage et la clause d'arbitrage, stipulée dans un contrat d'assurance, n'e…
2019
International audience; (Cass. 5 sept. 2018, n° S 17-13.837, F-D, Soc. RSUI Indemnity Company c/ Soc. Tenergie Developpement et autres, inédit)
La création d'un droit spécifique de l'arbitrage international des litiges de la consommation
2021
International audience; (Civ. 1re, 30 sept. 2020, n° M 18-19.241 (FS-P+B), Sté PWC Landwell / MA. Lefebvre et autres, D. actu. 19 oct. 2020, note J. Jourdan-Marqués, 1949 ; D. 2020. 2501, note D. Mouralis ; ibid. 2484, obs. T. Clay ; ibid. 2021. 594, obs. H. Aubry, E. Poillot et N. Sauphanor-Brouillaud ; ibid. 923, obs. S. Clavel et F. Jault-Seseke ; AJ contrat 2020. 485, obs. D. Mainguy ; Rev. prat. rec. 2021. 39, chron. R. Bouniol ; Rev. crit. DIP 2021. 202, note E. Loquin ; RTD civ. 2020. 845, obs. L. Usunier ; JCP 2020. 311, note M. de Fontmichel ; JDI 2020. 1307, note E. Gaillard)