Search results for "Computer Science Applications"
showing 10 items of 3993 documents
Molecular dynamics, dynamic site mapping, and highthroughput virtual screening on leptin and the Ob receptor as anti-obesity target.
2014
Body weight control is a mechanism finely regulated by several hormonal, metabolic, and nervous pathways. The leptin receptor (Ob-R) is crucial for energy homeostasis and regulation of food uptake. Leptin is a 16 kDa hormone that is mainly secreted by fat cells into the bloodstream, and under normal circumstances, circulating levels are proportionate to the fat body mass. Sensing of elevated leptin levels by the hypothalamic neurocircutry activates a negative feedback loop resulting in reduced food intake and increased energy expenditure. Decreased concentrations lead to opposite effects. Therefore rational design of leptin agonists constitute an appealing challenge in the battle against ob…
Architecture-Driven Level Set Optimization: From Clustering to Sub-pixel Image Segmentation
2016
Thanks to their effectiveness, active contour models (ACMs) are of great interest for computer vision scientists. The level set methods (LSMs) refer to the class of geometric active contours. Comparing with the other ACMs, in addition to subpixel accuracy, it has the intrinsic ability to automatically handle topological changes. Nevertheless, the LSMs are computationally expensive. A solution for their time consumption problem can be hardware acceleration using some massively parallel devices such as graphics processing units (GPUs). But the question is: which accuracy can we reach while still maintaining an adequate algorithm to massively parallel architecture? In this paper, we attempt to…
A LiDAR Prototype with Silicon Photomultiplier and MEMS Mirrors
2018
In this paper, we present a low cost prototype of a Time-Of-Flight (TOF) LiDAR system, employing a SiPM as photo detector and MEMS mirrors in order to steer the nanosecond pulsed optical beam with a scanning angle of +/-6°. Preliminary TOF measurements have been performed both indoor and outdoor to test the limits of the system.
Quantifying water stress effect on daily light use efficiency in Mediterranean ecosystems using satellite data
2016
16 pages, 2 figures, 6 tables, supplemental material https://dx.doi.org/10.1080/17538947.2016.1247301
Guanosine-Mediated Anxiolytic-Like Effect: Interplay with Adenosine A1 and A2A Receptors
2020
Acute or chronic administration of guanosine (GUO) induces anxiolytic-like effects, for which the adenosine (ADO) system involvement has been postulated yet without a direct experimental evidence. Thus, we aimed to investigate whether adenosine receptors (ARs) are involved in the GUO-mediated anxiolytic-like effect, evaluated by three anxiety-related paradigms in rats. First, we confirmed that acute treatment with GUO exerts an anxiolytic-like effect. Subsequently, we investigated the effects of pretreatment with ADO or A1R (CPA, CCPA) or A2AR (CGS21680) agonists 10 min prior to GUO on a GUO-induced anxiolytic-like effect. All the combined treatments blocked the GUO anxiolytic-like effect, …
Effects of Candelilla and Carnauba Wax Incorporation on the Functional Properties of Edible Sodium Caseinate Films
2020
International audience; The aim of this study was to evaluate the effects of candelilla (CAN) or carnauba wax (CAR) incorporation on functional properties of edible sodium caseinate (CAS) films. Glycerol and Tween-80 were used as the plasticizer and the emulsifier, respectively. The results showed that the incorporation of waxes increased film opacity, total color differences (∆E), and mechanical resistance and reduced film lightness, water vapor permeability (WVP), and elongation at break. Scanning electron microscopy showed heterogeneous structure of emulsion films with regular distribution of lipid particles. A different internal arrangement was observed as a function of the film composi…
Early assessment of crop yield from remotely sensed water stress and solar radiation data
2018
Soil moisture (SM) available for evapotranspiration is crucial for food security, given the significant interannual yield variability of rainfed crops in large agricultural regions. Also, incoming solar radiation (Rs) influences the photosynthetic rate of vegetated surfaces and can affect productivity. The aim of this work is to evaluate the ability of crop water stress and Rs remotely sensed data to forecast yield at regional scale. Temperature Vegetation Dryness Index (TVDI) was computed as an indicator of crop water stress and soil moisture availability. TVDI during critical growth stage of crops was calculated from MODIS products: MODIS/AQUA 8-day composite LST at 1 km and 16-day compos…
Innovative straight formulation for plate in bending
2017
In this paper it has been introduced an innovative formulation for evaluating the deflection function of a simply supported plate loaded by uniformly distributed edge moments. Framed into Line Element-less Method, this formulation allows the evaluation of solution in terms of deflection, through few lines of algorithm implemented by Mathematica software without resorting to any discretization neither in the domain nor in the boundary. Interesting savings in terms of time and computational costs are achieved. Results obtained by the proposed method are well contrasted by ones obtained by classical methods and Finite Element Method.
Steiner systems and configurations of points
2020
AbstractThe aim of this paper is to make a connection between design theory and algebraic geometry/commutative algebra. In particular, given any Steiner SystemS(t, n, v) we associate two ideals, in a suitable polynomial ring, defining a Steiner configuration of points and its Complement. We focus on the latter, studying its homological invariants, such as Hilbert Function and Betti numbers. We also study symbolic and regular powers associated to the ideal defining a Complement of a Steiner configuration of points, finding its Waldschmidt constant, regularity, bounds on its resurgence and asymptotic resurgence. We also compute the parameters of linear codes associated to any Steiner configur…
Fault detection for discrete-time Markov jump linear systems with partially known transition probabilities
2010
In this article, the fault detection (FD) problem for a class of discrete-time Markov jump linear system (MJLS) with partially known transition probabilities is investigated. The proposed systems are more general, which relax the traditional assumption in Markov jump systems that all the transition probabilities must be completely known. A residual generator is constructed and the corresponding FD is formulated as an H ∞ filtering problem by which the error between residual and fault are minimised in the H ∞ sense. The linear matrix inequality-based sufficient conditions for the existence of FD filter are derived. A numerical example on a multiplier–accelerator model economic system is give…