Search results for "Computer Science Applications"
showing 10 items of 3993 documents
Progress of Phototherapy Applications in the Treatment of Bone Cancer
2021
Bone cancer including primary bone cancer and metastatic bone cancer, remains a challenge claiming millions of lives and affecting the life quality of survivors. Conventional treatments of bone cancer include wide surgical resection, radiotherapy, and chemotherapy. However, some bone cancer cells may remain or recur in the local area after resection, some are highly resistant to chemotherapy, and some are insensitive to radiotherapy. Phototherapy (PT) including photodynamic therapy (PDT) and photothermal therapy (PTT), is a clinically approved, minimally invasive, and highly selective treatment, and has been widely reported for cancer therapy. Under the irradiation of light of a specific wa…
Fertility sparing treatments in endometrial cancer patients: the potential role of the new molecular classification
2021
Endometrial cancer is the most frequent gynecological malignancy, and, although epidemiologically it mainly affects advanced age women, it can also affect young patients who want children and who have not yet completed their procreative project. Fertility sparing treatments are the subject of many studies and research in continuous evolution, and represent a light of hope for young cancer patients who find themselves having to face an oncological path before fulfilling their desire for motherhood. The advances in molecular biology and the more precise clinical and prognostic classification of endometrial cancer based on the 2013 The Cancer Genome Atlas classification allow for the selection…
MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients
2020
Single nucleotide polymorphisms (SNPs) in Pharmacogenetics can play an important role in the outcomes of the chemotherapy treatment in Neuroblastoma, helping doctors maximize efficacy and minimize toxicity. Employing AgenaBioscience MassArray, 96 SNPs were genotyped in 95 patients looking for associations of SNP with response to induction therapy (RIT) and grade 3&ndash
Circulating miR-99a-5p Expression in Plasma: A Potential Biomarker for Early Diagnosis of Breast Cancer
2020
MicroRNAs have emerged as new diagnostic and therapeutic biomarkers for breast cancer. Herein, we analysed miR-99a-5p expression levels in primary tumours and plasma of breast cancer patients to evaluate its usefulness as a minimally invasive diagnostic biomarker. MiR-99a-5p expression levels were determined by quantitative real-time PCR in three independent cohorts of patients: (I) Discovery cohort: breast cancer tissues (n = 103) and healthy breast tissues (n = 26)
When Methodology Interferes With Substance
2005
For campaigners, and also attendant researchers, the advent of the Internet has challenged established ways of doing their respective campaign business. Practitioners, used to running local and media campaigns, can nowadays also resort to elements of web campaigning, while electoral researchers, used to running election studies based on personal or telephone interviews, can now employ online surveys to do their business. However, e-campaigning and online polling suffer from severe deficiencies. Based on online and offline surveys conducted in the run-up to the 2002 German election, we show two things. First, online surveys yield biased results; second, e-campaigning reaches only a tiny fra…
More restrictive Gray codes for necklaces and Lyndon words
2008
In the last years, the order induced by the Binary Reflected Gray Code or its generalizations shown an increasing interest. In this note we show that the BRGC order induces a cyclic 2-Gray code on the set of binary necklaces and Lyndon words and a cyclic 3-Gray code on the unordered counterparts. This is an improvement and a generalization to unlabeled words of the result in [V. Vajnovszki, Gray code order for Lyndon words, Discrete Math. Theoret. Comput. Sci. 9 (2) (2007) 145-152; M. Weston, V. Vajnovszki, Gray codes for necklaces and Lyndon words of arbitrary base, Pure Mathematics and Applications/Algebra and Theoretical Computer Science, in press]; however an algorithmic implementation …
Title: The Emergency Medicine Facing the Challenge of Open Science
2020
This article belongs to the Special Issue Data Reuse for Sustainable Development Goals.
Toward Unified Control of Networks of Switches and Sensors Through a Network Operating System
2018
Wireless sensor networks (WSNs) are an integral part of an Internet of Things (IoT) ecosystem. In fact, a typical IoT service deployment considers an integrated network of switches and sensors (as well as actuators). In order to manage this heterogeneous network infrastructure, the use of software defined networking (SDN) technologies is anticipated. However, existing SDN-enabling technologies consider only isolated networks and there has been no concrete solution that treats the whole network in a unified way. In this paper, a network operating system is proposed as a way to address the above issue. Starting from the open network operating system, which currently supports only OpenFlow net…
Analysis of the road traffic management system in the neural network development perspective
2019
The research goal of the paper is to present the issues connected with road traffic management systems and to illustrate a management system that uses Intelligent Transportation Systems and neural networks. The use of Intelligent Transportation Systems (ITS) is a method of improving the conditions of communications, making it independent from the development of communications infrastructure. The attributes of neural networks are focused on solving the problems of optimisation, which involve the development of optimal strategies for traffic management. The proposed road traffic management system that uses ITS and neural networks can be applied in prediction of the conditions of communication…
Forecasting Adverse Weather Situations in the Road Network
2016
Weather is an important factor that affects traffic flow and road safety. Adverse weather situations affect the driving conditions directly; hence, drivers must be informed about the weather conditions downstream to adapt their driving. In the framework of intelligent transport systems, several systems have been developed to know the weather situations and inform drivers. However, these systems do not forecast weather in advance, and they need the support of road operators to inform drivers. This paper presents a new autonomous system to forecast weather conditions in a short time and to give users the information obtained. The system uses a set of algorithms and rules to determine the weat…