Search results for "Computer program"

Solvent-induced free energy landscape and solute-solvent dynamic coupling in a multielement solute

1999

AbstractMolecular dynamics simulations using a simple multielement model solute with internal degrees of freedom and accounting for solvent-induced interactions to all orders in explicit water are reported. The potential energy landscape of the solute is flat in vacuo. However, the sole untruncated solvent-induced interactions between apolar (hydrophobic) and charged elements generate a rich landscape of potential of mean force exhibiting typical features of protein landscapes. Despite the simplicity of our solute, the depth of minima in this landscape is not far in size from free energies that stabilize protein conformations. Dynamical coupling between configurational switching of the syst…

Neutrinoless double beta decay and QCD running at low energy scales

2018

There is a common belief that the main uncertainties in the theoretical analysis of neutrinoless double beta ($0\nu\beta\beta$) decay originate from the nuclear matrix elements. Here, we uncover another previously overlooked source of potentially large uncertainties stemming from non-perturbative QCD effects. Recently perturbative QCD corrections have been calculated for all dimension 6 and 9 effective operators describing $0\nu\beta\beta$-decay and their importance for a reliable treatment of $0\nu\beta\beta$-decay has been demonstrated. However, these perturbative results are valid at energy scales above $\sim 1$ GeV, while the typical $0\nu\beta\beta$-scale is about $\sim 100$ MeV. In vi…

Non-perturbative renormalisation of left left four-fermion operators with Neuberger fermions

2006

We outline a general strategy for the non-perturbative renormalisation of composite operators in discretisations based on Neuberger fermions, via a matching to results obtained with Wilson-type fermions. As an application, we consider the renormalisation of the four-quark operators entering the Delta S=1 and Delta S=2 effective Hamiltonians. Our results are an essential ingredient for the determination of the low-energy constants governing non-leptonic kaon decays.

Semileptonic decays of light quarks beyond the Standard Model

2009

We describe non-standard contributions to semileptonic processes in a model independent way in terms of in SU(2)(L) x U(1)(Y) invariant effective lagrangian at the weak scale, front which we derive the low-energy effective lagrangian governing muon and beta decays. We find that the deviation from Cabibbo universality, Delta(CKM) equivalent to vertical bar V-ud vertical bar(2) + vertical bar V-us vertical bar(2) + vertical bar V-ub vertical bar(2) - 1, receives contributions from four effective operators. The phenomenological bound Delta(CKM) = (-1 +/- 6) x 10(-4) provides strong constraints on all four operators, corresponding to art effective scale Lambda > 11 TeV (90% CL). Depending on th…

Quantitative online isolation of 68Ge from 68Ge/68Ga generator eluates for purification and immediate quality control of breakthrough

2013

The breakthrough of ⁶⁸Ge from a ⁶⁸Ge/⁶⁸Ga-generator is one of the most sensitive parameters in the context of the clinical application of ⁶⁸Ga-radiopharmaceuticals. The difficulty in its determination lies in the "spectroscopic invisibility" of ⁶⁸Ge within an excess of ⁶⁸Ga. The introduced method for determining the ⁶⁸Ge content of the ⁶⁸Ge/⁶⁸Ga-generator eluate involves the quantitative separation of ⁶⁸Ga from ⁶⁸Ge, using a cation-exchanger. The eluate contains ⁶⁸Ga free of ⁶⁸Ge, which can be determined immediately, i.e. prior to the application of the ⁶⁸Ga-radiopharmaceutical.

Numerical expressions for the computation of coincidence-summing correction factors in γ-ray spectrometry with HPGe detectors

2009

Numerical expressions to compute gamma-gamma and gamma-X(K) coincidence summing corrections were deduced by using a suitable computer program and a matrix representation of a decay scheme. For point sources only full-energy peak and total efficiencies are needed. Alternatively, values of peak-to-total ratio can be introduced. For extended sources, the same expressions can be considered with the introduction of "effective efficiencies". Examples of the use of the expressions for point sources and a particulate filter sample measured with a 60% relative efficiency HPGe detector are reported.

68Ge content quality control of 68Ge/68Ga-generator eluates and 68Ga radiopharmaceuticals – A protocol for determining the 68Ge content using thin-la…

2014

(68)Ge breakthrough from a (68)Ge/(68)Ga-generator appears to be one of the most critical parameters for the routine clinical application of this generator and (68)Ga-radiopharmaceuticals. We report a TLC-based (thin-layer chromatography) protocol which allows the (68)Ge breakthrough of a generator to be determined within 1 h post-initial elution. The protocol can also be adapted to allow the (68)Ge content of a (68)Ga-radiopharmaceutical preparation to be determined prior to in vivo application.

Resolvent Estimates Near the Boundary of the Range of the Symbol

2019

The purpose of this chapter is to give quite explicit bounds on the resolvent near the boundary of Σ(p) (or more generally, near certain “generic boundary-like” points.) The result is due (up to a small generalization) to Montrieux (Estimation de resolvante et construction de quasimode pres du bord du pseudospectre, 2013) and improves earlier results by Martinet (Sur les proprietes spectrales d’operateurs nonautoadjoints provenant de la mecanique des fluides, 2009) about upper and lower bounds for the norm of the resolvent of the complex Airy operator, which has empty spectrum (Almog, SIAM J Math Anal 40:824–850, 2008). There are more results about upper bounds, and some of them will be rec…

Identification of Precious Artefacts: The Sonic Imprint for Small Artefacts

2010

Identification of artworks is mainly based on a few characteristics which can be observed using non-invasive tools (sight, touch, simple instruments), the investigated properties being geometry, weight, colours, texture, etc. Nowadays, technology allows reproducing all these characteristics to such an extent that even expert conservators can be deceived: in particular at the present time even the geometry of an artwork can be easily reproduced with the help of laser scanner analysis and with a rapid prototyping machine or a computer numerical control (CNC) milling machine. We propose a new tool, the Sonic Imprint, producing a code capable of identifying a rigid artefact from its vibrational…

2019

Abstract This article considers the implementation of a new learning subject ”Technology Comprehension” into lower secondary schools in Denmark, as part of an initiative by the Danish Ministry of Education. The subject consists of learning objectives related to computing, design, and societal reflection and was first introduced as an elective course in 13 schools to investigate how it could be integrated into the Danish education system. We present four key findings based on school visits, interviews, an electronical survey, two questionnaires, and workshops including theme discussions: (1) teachers did not perceive Technology Comprehension as a distinct subject, but rather as a set of skil…