Search results for "Control"
showing 10 items of 13168 documents
Meta-analysis
2012
Treatment of the pain caused by chronic pancreatitis (CP) is not standardized. Knowledge of the response to placebo in this setting may aid the design of future trials. We aimed at investigating the placebo effect on abdominal pain remission rates in patients with CP.MEDLINE, EMBASE, and Scopus were searched, and randomized placebo-controlled trials in CP providing data on abdominal pain remission rates in placebo arms were included. Pooled estimates of the placebo rate were calculated using random-effects logistic regression analysis. Stratum-specific rates for different patients and study-level covariates were calculated to account for heterogeneity.Seven randomized controlled trials (202…
Effects of controlled-release on the pharmacokinetics and absorption characteristics of a compound undergoing intestinal efflux in humans
2006
Abstract Objective The number of active pharmaceutical ingredients (API) undergoing inhibitable and saturable intestinal efflux is considerable. As a consequence, absorption and bioavailability may depend on the intestinal concentration profile of the drug and may vary as a function of dose and release rate of the drug from the dosage form. The impact of controlled versus immediate-release on the absorption of P-glycoprotein substrates is currently unknown. Thus, the main focus of the present study was a comparison of the pharmacokinetics of the P-gp model substrate talinolol following administration of immediate-release (IR) and controlled-release (CR) tablets to healthy human volunteers w…
Acute effects of exercise and active video games on adults’ reaction time and perceived exertion
2016
The purpose of the present study was to examine the acute effects of resting, aerobic exercise practised alone, and aerobic exercise with active video games (AVG), on complex reaction time (CRT) and the post-exercise acute rate of perceived exertion (RPE) in young healthy adults. The experimental group was composed of 92 healthy young adults, 78 males and 13 females (age M = 21.9 ± 2.7 years) who completed two sessions, A and B. In session A, participants rode 30 min on an ergometer, while in session B they exercised for 30 min on an ergometer while playing an AVG on a Wii. The control group was composed of 30 young adults, 26 males and 4 females (age M = 21.4 ± 2.9 years) who rested for 30…
Behavioral Precursors to Accidents and Resulting Physical Impairment
1995
The main goal of the study was to determine, within a model of emotional and behavioral regulation, if there are developmental precursors to accidents and resulting physical impairment. Data collected at ages 8 and 14 with 147 males and 142 females using peer nomination and teacher rating were related to the number of types of accidents the subjects had been in and impairment as a result of an accident by the age of 27 when the subjects were interviewed on their health. The results showed that 44% of the men and 14% of the women had been in an accident. Severe effects on health were obtained for 19% of the men and 5% of the women. Accidents and impairment were most frequent among individual…
Devil in disguise : does drinking lead to a disability pension?
2016
Abstract Objectives To examine whether alcohol consumption in adulthood is related to the incidence of receiving a disability pension later in life. Methods Twin data for Finnish men and women born before 1958 were matched to register-based individual information on disability pensions. Twin differences were used to eliminate both shared environmental and genetic factors. The quantity of alcohol consumption was measured as the weekly average consumption using self-reported data from three surveys (1975, 1981 and 1990). The disability pension data were evaluated from 1990–2004. Results The models that account for shared environmental and genetic factors reveal that heavy drinkers are signifi…
Fear, danger and aggression in a Norwegian locked psychiatric ward
2014
Background: Fear and aggression are often reported among professionals working in locked psychiatric wards and also among the patients in the same wards. Such situations often lead to coercive intervention. In order to prevent coercion, we need to understand what happens in dangerous situations and how patients and professionals interpret them. Research questions: What happens when dangerous situations occur in a ward? How do professionals and patients interpret these situations and what is ethically at stake? Research design: Participant observation and interviews. Participants: A total of 12 patients and 22 professionals participated. Ethical considerations: This study has been accepted b…
The time course of orthography and phonology: ERP correlates of masked priming effects in Spanish
2009
Abstract One key issue for computational models of visual-word recognition is the time course of orthographic and phonological information during reading. Previous research, using both behavioral and event related brain potential (ERP) measures, has shown that orthographic codes are activated very early but that phonological activation starts to occur immediately afterward. Here we report an ERP masked priming experiment in Spanish that investigates this issue further by using very strict control conditions. The critical phonological comparison was between two pairs of primes having the same orthographic similarity to the target words but differing in phonological similarity (e.g., conal-CA…
Prismatic lenses shift time perception
2009
Previous studies have demonstrated the involvement of spatial codes in the representation of time and numbers. We took advantage of a well-known spatial modulation (prismatic adaptation) to test the hypothesis that the representation of time is spatially oriented from left to right, with smaller time intervals being represented to the left of larger time intervals. Healthy subjects performed a time-reproduction task and a time-bisection task, before and after leftward and rightward prismatic adaptation. Results showed that prismatic adaptation inducing a rightward orientation of spatial attention produced an overestimation of time intervals, whereas prismatic adaptation inducing a leftward…
Nurse-patient power relationship: preliminary evidence of patients' power messages.
2002
The interactive relationship that is based on sharing power and control is the goal of health counseling practice. This research examined the nurse-patient power relationship and emphasized the patient's perspective. Health counseling sessions, 38 in number, were videotaped, transcribed verbatim, and analyzed by using an adaptation of conversation analysis (CA). The purpose of this research was to describe in detail how patients' minimized power asymmetry during hospital counseling. The results indicate that power is a complex and polysemic phenomenon that can be created jointly. Nurses' power is associated with their medical knowledge, which also patients construct. However, patients have …
Social factors related to the clinical severity of influenza cases in Spain during the A (H1N1) 2009 virus pandemic
2013
Abstract Background During the 2009 influenza pandemic, a change in the type of patients most often affected by influenza was observed. The objective of this study was to assess the role of individual and social determinants in hospitalizations due to influenza A (H1N1) 2009 infection. Methods We studied hospitalized patients (cases) and outpatients (controls) with confirmed influenza A (H1N1) 2009 infection. A standardized questionnaire was used to collect data. Variables that might be related to the hospitalization of influenza cases were compared by estimation of the odds ratio (OR) and 95% confidence intervals (CI) and the variables entered into binomial logistic regression models. Resu…