Search results for "Cross infection"

showing 10 items of 103 documents

Performance of PSI, CURB-65, and SCAP scores in predicting the outcome of patients with community-acquired and healthcare-associated pneumonia

2011

The objective was to compare three score systems, pneumonia severity index (PSI), the Confusion-Urea-Respiratory Rate-Blood pressure-65 (CURB-65), and severe community-acquired pneumonia (SCAP), for prediction of the outcomes in a cohort of patients with community-acquired (CAP) and healthcare-associated pneumonia (HCAP). Large multi-center, prospective, observational study was conducted in 55 hospitals. HCAP patients were included in the high classes of CURB-65, PSI and SCAP scores have a mortality rate higher than that of CAP patients. HCAP patients included in the low class of the three severity rules have a significantly higher incidence of adverse events, including development of septi…

---medicine.medical_specialtySettore MED/09 - Medicina Internacommunity-acquired pneumoniaPneumonia severity indexBlood PressureSettore MED/10 - Malattie Dell'Apparato RespiratorioCommunity-acquired pneumonia Healthcare-associated pneumonia PSI CURB 65Severity of Illness IndexCommunity-acquired pneumoniaRespiratory RatePredictive Value of TestsInternal medicineCURB 65Severity of illnessInternal MedicinePneumonia BacterialMedicineHumansUreaPSIProspective StudiesIntensive care medicineProspective cohort studyConfusion---; community-acquired pneumonia; Healthcare-associated pneumonia; PSI; CURB 65Cross Infectioncommunity-acquired pneumonia; psi; healthcare-associated pneumonia; curb 65business.industryMortality ratemedicine.diseasePrognosisCURB-65Settore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheHealthcare-associated pneumoniaCommunity-Acquired InfectionsPneumoniaCohortEmergency Medicinebusiness
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Antibiotic treatment of infections caused by carbapenem-resistant Gram-negative bacilli: an international ESCMID cross-sectional survey among infecti…

2018

ESGAP, ESGBIS, ESGIE and the CRGNB treatment survey study group.

0301 basic medicineAcinetobacter baumanniiCarbapenemAntibioticsDrug ResistanceDrug resistanceTigecyclineAcinetobacter baumannii; Carbapenem; Carbapenem-resistant Gram-negative bacilli; Combination therapy; Enterobacteriaceae; Polymyxin; Pseudomonas aeruginosa; SurveyPolymyxin0302 clinical medicineSurveys and Questionnairespolycyclic compounds030212 general & internal medicineAcinetobacter baumannii; Carbapenem; Carbapenem-resistant Gram-negative bacilli; Combination therapy; Enterobacteriaceae; Polymyxin; Pseudomonas aeruginosa; Survey; Anti-Bacterial Agents; Carbapenems; Cross Infection; Cross-Sectional Studies; Drug Resistance Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals; Humans; Microbial Sensitivity Tests; Surveys and QuestionnairesSurveyCarbapenemAcinetobacter baumannii; Carbapenem; Carbapenem-resistant Gram-negative bacilli; Combination therapy; Enterobacteriaceae; Polymyxin; Pseudomonas aeruginosa; Survey; Anti-Bacterial Agents; Carbapenems; Cross Infection; Cross-Sectional Studies; Drug Resistance Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals; Humans; Microbial Sensitivity Tests; Surveys and Questionnaires; Microbiology (medical); Infectious DiseasesCross InfectionbiologyMicrobial Sensitivity TestCarbapenem-resistant Gram-negative bacilliBacterialantibiotic management carbapenem-resistant Gram-negative bacteriaGeneral MedicineHospitals3. Good healthAcinetobacter baumanniiAnti-Bacterial AgentsInfectious DiseasesPseudomonas aeruginosamedicine.drugHumanMicrobiology (medical)medicine.medical_specialtymedicine.drug_class030106 microbiologyMicrobial Sensitivity TestsFosfomycincarbapenem-resistant Gram-negative bacteria03 medical and health sciencesHospitalEnterobacteriaceaeInternal medicineAnti-Bacterial AgentDrug Resistance BacterialGram-Negative BacteriamedicineGram-Negative Bacterial InfectionHumansCombination therapyCross-Sectional Studiebusiness.industrybiochemical phenomena metabolism and nutritionbiology.organism_classificationbacterial infections and mycosesCross-Sectional StudiesCarbapenemsInfectious disease (medical specialty)Carbapenem-resistant gram-negative bacilli[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieantibiotic managementbusinessGram-Negative Bacterial InfectionsRifampicin
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Candida thrombophlebitis in children: a systematic review of the literature

2020

Abstract Objective To describe a case of thrombophlebitis associated with Candida infection and to analyze other published reports to define clinical characteristics, prognostic data, diagnostic and therapeutic strategies. Study design A computerized search was performed without language restriction using PubMed and Scopus databases. An article was considered eligible for inclusion if it reported cases with Candida thrombophlebitis. Our case was also included in the analysis. Results A total of 16 articles reporting 27 cases of Candida thrombophlebitis were included in our review. The median age of patients was 4 years. In 10 cases there was a thrombophlebitis of peripheral veins; in the re…

0301 basic medicineAntifungal Agentsmedicine.medical_treatmentReviewThrombophlebitislaw.invention0302 clinical medicineRisk FactorslawAmphotericin BThrombosis.030212 general & internal medicineChildPersistent feverAntifungal therapyChildrenCandidaHospital-acquired infectionsCross InfectionAnticoagulantCandidiasislcsh:RJ1-570PrognosisIntensive care unitThrombosisChild PreschoolCentral venous cathetermedicine.drugmedicine.medical_specialtySepsimedicine.drug_class030106 microbiologySepsis03 medical and health sciencesAmphotericin BSepsisInternal medicinemedicineHumansEnoxaparinbusiness.industryAnticoagulantsThrombosislcsh:PediatricsThrombophlebitisNewbornmedicine.diseaseHospital-acquired infectionParenteral nutritionPhlebitisbusinessItalian Journal of Pediatrics
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Genotyping and Antifungal Susceptibility of Dipodascus capitatus Isolated in a Neonatal Intensive Care Unit of a Sicilian Hospital

2017

In August 2015, Dipodascus capitatus was isolated from two patients admitted to the neonatal intensive care unit. Nosocomial acquisition of the fungus was suspected and epidemiological studies were undertaken. The patients were simultaneously hospitalized, and the comparison of the two isolates by two independent molecular typing methods have confirmed clonal dissemination of a single strain of D. capitatus. Antimicrobial susceptibility testing was useful for identifying the appropriated antifungal therapy in micafungin. To our knowledge these are the first described cases of neonatal D. capitatus infection and also the first report of successful treatment by micafungin.

0301 basic medicineAntifungalGenotypingPediatricsmedicine.medical_specialtyClonal disseminationNeonatal intensive care unitmedicine.drug_class030106 microbiologyDipodascus03 medical and health sciencesEpidemiologymedicineDipodascus capitatuAntifungal SusceptibilityDipodascus capitatusGenotypingBiochemistry Genetics and Molecular Biology (all)biologyMedicine (all)MicafunginAntifungal Susceptibility; Dipodascus capitatus; Genotyping; Nosocomial Acquisition; Cross Infection; Dipodascus; Female; Genotype; Hospitals; Humans; Infant; Infant Newborn; Intensive Care Units Neonatal; Male; Mycoses; Sicily; Medicine (all); Biochemistry Genetics and Molecular Biology (all)biology.organism_classificationNosocomial AcquisitionAntifungal Susceptibility; Dipodascus capitatus; Genotyping; Nosocomial Acquisition; Medicine (all); Biochemistry Genetics and Molecular Biology (all)medicine.drug
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Trends of extended-spectrum β-lactamase-producing Escherichia coli sequence type 131 and its H30 subclone in a French hospital over a 15-year period.

2016

International audience; Sequence type 131 (ST131) is a predominant lineage among extraintestinal pathogenic Escherichia coli. It plays a major role in the worldwide dissemination of E. coli producing extended-spectrum β-lactamases (ESBLs). Here we describe the long-term epidemiology of this clonal group in a French university hospital, where the incidence of ESBL-producing E. coli has increased from 0.018 case per 1000 patient-days in the year 2000 to 0.50 case per 1000 patient-days in 2014. The first of the 141 ST131 isolates was recovered in 2006, and the ST131 clonal group accounted for 18.1% of total ESBL-producing E. coli over the whole period (2000-2014). Subclonal typing showed that …

0301 basic medicineMESH : Escherichia coliMESH : Retrospective StudiesMESH : Multilocus Sequence TypingMESH: beta-LactamasesMESH : GenotypeMultidrug resistancemedicine.disease_causeHospitals UniversityMESH: Genotype[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyPharmacology (medical)MESH: IncidenceMESH: Genetic VariationEscherichia coli InfectionsComputingMilieux_MISCELLANEOUSCross InfectionMolecular EpidemiologyExtraintestinal Pathogenic Escherichia coliMESH: Escherichia coliIncidenceIncidence (epidemiology)MESH : beta-LactamasesGeneral MedicinePFGEMESH : IncidenceElectrophoresis Gel Pulsed-Field3. Good healthInfectious DiseasesMESH: Electrophoresis Gel Pulsed-FieldMESH: Multilocus Sequence Typing[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyMESH : Escherichia coli Infections[SDE]Environmental SciencesFranceMESH : Cross InfectionMicrobiology (medical)clone (Java method)Lineage (genetic)GenotypeMESH : Molecular Epidemiology030106 microbiologyBiologybeta-LactamasesMicrobiology03 medical and health sciencesExtended-spectrum β-lactamaseMESH : Genetic VariationEscherichia coliPulsed-field gel electrophoresismedicineHumansMESH: Molecular EpidemiologyTypingMESH : FranceEscherichia coliMESH : Hospitals UniversityRetrospective StudiesMESH : Electrophoresis Gel Pulsed-FieldMESH: Escherichia coli InfectionsMESH: Hospitals UniversityMESH: HumansMESH : HumansGenetic VariationMESH: Cross InfectionMESH: Retrospective Studiesbacterial infections and mycosesMultiple drug resistanceMESH: FranceESBLMultilocus Sequence Typing
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Efficacy of a coordinated strategy for containment of multidrug-resistant Gram-negative bacteria carriage in a Neonatal Intensive Care Unit in the co…

2021

AbstractBackgroundAntimicrobial resistance in neonatal intensive care unit (NICU) patients is a threat, due to the frequent use of antimicrobial treatment and invasive devices in fragile babies. Since 2014 an active surveillance program of multidrug-resistant Gram-negative bacteria (MDR-GNB) carriage has been in place in the five NICUs of Palermo, Italy. In 2017 an increase in the prevalence of MDR-GNB, and in particular of extended-spectrum β-lactamases-producingKlebsiella pneumoniae(ESBL-KP), was observed in “Civico” hospital NICU.AimTo assess the impact of a coordinated intervention strategy in achieving long-lasting reduction of MDR-GNB prevalence in the NICU.MethodsRectal swabs were ob…

0301 basic medicineMicrobiology (medical)Malemedicine.medical_specialtyNeonatal intensive care unit030106 microbiologyExtended spectrum β lactamases producing klebsiella pneumoniaeContext (language use)Drug resistanceMicrobial Sensitivity TestsAntimicrobial resistancelcsh:Infectious and parasitic diseases03 medical and health sciences0302 clinical medicineAntibiotic resistanceMedical microbiologyNeonatal intensive care unitInternal medicineDrug Resistance Multiple BacterialIntensive Care Units NeonatalGram-Negative BacteriamedicineHumansPharmacology (medical)lcsh:RC109-216030212 general & internal medicineNeonatal intensive care unit.Cross InfectionInfection ControlActive surveillance programbusiness.industryResearchPublic Health Environmental and Occupational HealthInfant NewbornAntimicrobialMulti-drug resistant gram-negative bacteriaElectrophoresis Gel Pulsed-FieldInfectious DiseasesCarriageItalyIntervention strategyCarrier StateFemaleSample collectionbusinessGram-Negative Bacterial Infections
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Factors associated with 12 week case-fatality in Staphylococcus aureus bacteraemia: a prospective cohort study

2016

International audience; Staphylococcus aureus bacteraemia (SAB) is a frequent and deadly disease. Given the lack of a randomized trial, optimal first-line antibiotic treatment is still debated. Our aim was to identify prognostic factors in SAB patients and to analyse the impact of first-line antibiotics. The VIRSTA prospective cohort study was conducted in eight tertiary care centres in France. Consecutive incident adults in whom a blood culture drawn in participating centres grew S. aureus between April 2009 and October 2011 were prospectively followed for 12 weeks. Factors associated with 12-week case-fatality were identified by multivariate logistic regression. We enrolled 2091 patients …

0301 basic medicineMicrobiology (medical)Malemedicine.medical_specialtyStaphylococcus aureusmedicine.drug_class030106 microbiologyAntibioticsBacteremiaPenicillinsPrognostic factorsTertiary Care Centers03 medical and health sciencesInterquartile range[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyVancomycinInternal medicineCase fatality ratemedicineHumansBlood cultureProspective StudiesProspective cohort study[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyAgedAntistaphylococcal penicillinsCross Infectionmedicine.diagnostic_testbusiness.industrySeptic shockGeneral MedicineMiddle AgedStaphylococcal Infectionsmedicine.diseasePrognosisSurvival Analysis3. Good healthSurgeryInfectious Diseases[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyVancomycinBacteraemiaAntistaphylococcal penicillinFemaleFrancebusinessmedicine.drug
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Ruling out nosocomial transmission of Cryptosporidium in a renal transplantation unit: case report

2016

Background Cryptosporidium spp. is a ubiquitous parasite affecting humans as well as domestic and wild vertebrates, causing diarrhea in both immunocompetent and immunocompromised hosts worldwide. Its transmission occurs primarily by the fecal-oral route. In humans, C. parvum and C. hominis are the most prevalent species, whereas immunocompetent and immunocompromised individuals can also be infected by other zoonotic species. Renal transplant patients are prone to develop cryptosporidiosis, which can induce severe and life-threatening diarrhea. Case presentation We report here a series of nearly concomitant cases of acute symptomatic cryptosporidiosis in three renal transplant patients atten…

0301 basic medicineNephrologyAdultDiarrheaMalemedicine.medical_specialty[SDV]Life Sciences [q-bio]030106 microbiologyCryptosporidiosisCryptosporidiumContext (language use)Case Report03 medical and health sciencesFecesImmunocompromised HostInternal medicinemedicineAnimalsHumans[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyGenotypingCross InfectionbiologyTransmission (medicine)NitazoxanideCryptosporidiumAcute Kidney InjuryMiddle Agedbiology.organism_classificationNitro CompoundsKidney Transplantation3. Good healthTransplantationDiarrheaThiazoles030104 developmental biologyInfectious DiseasesRenal transplant[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyImmunologyCoccidiostatsFemalemedicine.symptomZoonotic speciesmedicine.drugGenotypic species identification
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What is the risk of acquiring bacteria from prior intensive care unit bed occupants?

2017

0301 basic medicineRiskmedicine.medical_specialtyLetterMulti drug resistant bacteriaSepsi030106 microbiologyIntensive Care UnitBacterial contamination; Infection; Multi-drug resistant bacteria; SepsisBacterial contamination; Infection; Multi-drug resistant bacteria; Sepsis; Critical Care and Intensive Care MedicineMulti-drug resistant bacteriaCritical Care and Intensive Care Medicinelaw.inventionSepsis03 medical and health sciences0302 clinical medicinelawPatients' RoomSepsisPatients' RoomsAnti-Bacterial AgentHumansMedicineMultidrug-resistant gram-negative bacteriaMED/41 - ANESTESIOLOGIAIntensive care medicineCross InfectionInfection Controlbiologybusiness.industry030208 emergency & critical care medicinemedicine.diseasebiology.organism_classificationIntensive care unitAnti-Bacterial AgentsIntensive Care UnitsEquipment ContaminationbusinessInfectionBacteriaBacterial contaminationHuman
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Validation and implementation of a commercial real-time PCR assay for direct detection of Candida auris from surveillance samples.

2021

Background Rapid and reliable laboratory methods are required for detecting the nosocomial yeast Candida auris. AurisID® (Olm Diagnostics, England) is a real-time PCR assay approved for detecting C. auris in fungal cultures as well as directly from blood samples, involving a nucleic acid extraction as a prior step. Objectives The purpose of this study is to validate the AurisID® kit for direct detection of C. auris from surveillance samples without prior DNA extraction and to analyze the results of implementing this methodology to our daily laboratory routine protocol for C. auris surveillance studies. Methods Our PCR method using the AurisID® kit was compared with our routine protocol, con…

0301 basic medicineSerial dilution030106 microbiologyPcr assayDermatologyReal-Time Polymerase Chain ReactionSensitivity and Specificity030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineLimit of DetectionTransport mediumMedicineHumansDNA FungalCandidaDetection limitCross InfectionChromatographybusiness.industryDiagnostic Tests RoutineCandidiasisGeneral MedicineDNA extractionInfectious DiseasesReal-time polymerase chain reactionCandida aurisMolecular Diagnostic TechniquesEpidemiological MonitoringPcr methodbusinessMycosesREFERENCES
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