Search results for "Cyst"

showing 10 items of 1960 documents

Usefulness of Clinical Data and Biomarkers for the Identification of Frailty After Acute Coronary Syndromes

2015

Abstract Background Frailty predicts mortality after acute coronary syndrome (ACS). The standard frailty scales, such as the Fried score, consist of a variety of questionnaires and physical tests. Our aim was to investigate easily available clinical data and blood markers to predict frailty at discharge, in elderly patients after ACS. Methods A total of 342 patients older than 65 years, survivors after ACS, were included. A high number of clinical variables were collected. In addition, blood markers potentially linked to frailty and related to the processes of inflammation, coagulation, hormonal dysregulation, nutrition, renal dysfunction, and heart dysfunction were determined. Frailty was …

Malemedicine.medical_specialtyAcute coronary syndromeFrail ElderlyMyocardial InfarctionComorbidityDiseaseCohort StudiesRisk FactorsInternal medicineVitamin D and neurologyHumansMedicineMyocardial infarctionAcute Coronary SyndromeCystatin CVitamin DGeriatric AssessmentAgedAged 80 and overbusiness.industryPrognosismedicine.diseaseComorbidityPatient DischargeSurgeryPatient Outcome AssessmentHeart failureHemoglobinometryBiomarker (medicine)FemaleCardiology and Cardiovascular MedicinebusinessBiomarkersFollow-Up StudiesCohort studyCanadian Journal of Cardiology
researchProduct

Early determination of homocysteine levels in acute coronary syndromes, is it an independent prognostic factor?

2004

Abstract Introduction Increased concentrations of homocysteine (tHcy) are considered a potentially modifiable risk factor for coronary heart disease. The relationship between plasma homocysteine and prognosis has been less well studied. The aim of this study was to examine a possible relationship between the homocysteine levels in admission and all cause mortality in subjects presenting with non-ST segment elevation (NSTE) acute coronary syndrome. Methods We studied 854 patients with suspected NSTE acute coronary syndrome admitted consecutively to our institution, tHcy was determined at a median of 3 days from enrolment and was analyzed in tertiles together with classical risk factors and o…

Malemedicine.medical_specialtyAcute coronary syndromeHomocysteineMyocardial InfarctionCoronary Diseasechemistry.chemical_compoundInternal medicinemedicineClinical endpointHumansRisk factorHomocysteineAgedCreatinineAnalysis of Variancebiologybusiness.industryAcute-phase proteinmedicine.diseasePrognosisTroponinSurvival AnalysisSurgerychemistrySpainHeart failureCardiologybiology.proteinLinear ModelsFemaleCardiology and Cardiovascular MedicinebusinessBiomarkersInternational journal of cardiology
researchProduct

Homocysteine and long-term recurrent infarction following an acute coronary syndrome.

2021

En Cardiology Journal. Gdańsk (Polonia) : Via Medica. Vol. 28, n. 4 (01 jul. 2021), pp. 598-606. ISSN 1897-5593. e-ISSN 1898-018X. Este artículo se encuentra disponible en la siguiente URL: https://journals.viamedica.pl/cardiology_journal/article/view/CJ.a2020.0170/52602 En este artículo de investigación también participan: Maria Marco, Teresa García-Ballester, Begoña Zorio, Eduardo Núñez, Francisco J. Chorro, Juan Sanchis y Julio Núñez. Background: There are no well-established predictors of recurrent ischemic coronary events after an acute coronary syndrome (ACS). Higher levels of homocysteine have been reported to be associated with an increased atherosclerotic burden. The primary endpoi…

Malemedicine.medical_specialtyAcute coronary syndromeHomocysteinemedicine.medical_treatmentCoronary heart disease - Risk factors.Infarto de miocardio - Factores de riesgo.Enfermedad coronaria - Factores de riesgo.InfarctionClinical CardiologyRevascularizationCoronary artery diseasechemistry.chemical_compoundInterquartile rangeRisk FactorsInternal medicineMyocardial infarction - Risk factors.medicineHumansMyocardial infarctionAcute Coronary SyndromeHomocysteineAgedacute coronary syndrome coronary artery disease homocysteine recurrent myocardial infarction risk factorsCardiovascular system - Diseases - Risk factors.Framingham Risk Scorebusiness.industryEnfermedades cardiovasculares - Factores de riesgo.General Medicinemedicine.diseaseHospitalizationchemistryCardiologyST Elevation Myocardial InfarctionCardiology and Cardiovascular MedicinebusinessCardiology journal
researchProduct

Familial insulin resistant diabetes associated with acanthosis nigricans, polycystic ovaries, hypogonadism, pigmentary retinopathy, labyrinthine deaf…

1993

Two sibs, whose parents are first cousins, had diabetes mellitus with hyperinsulinism, insensitive insulin receptors, and acanthosis nigricans. Both patients had pigmentary retinopathy, secondary cataracts, labyrinthine deafness, mental retardation, and cerebral atrophy. They were disproportionately short with relatively broad hands and feet and slightly coarse face. The young woman had secondary amenorrhea and polycystic ovaries and the boy gynecomastia and hypergonadotrophic hypogonadism. This appears to be the second family with a new autosomal recessive disorder differing from Alstrom syndrome by the presence of mental retardation and absence of renal insufficiency. Impaired insulin rec…

Malemedicine.medical_specialtyAdolescentHearing Loss SensorineuralGenes RecessiveConsanguinityInternal medicineDiabetes mellitusIntellectual DisabilityMedicineHumansAcanthosis NigricansAcanthosis nigricansGenetics (clinical)business.industryHypogonadismSyndromemedicine.diseasePolycystic ovaryEndocrinologyGynecomastiaDiabetes Mellitus Type 2Insulin receptor bindingFemaleInsulin ResistancebusinessHyperinsulinismRetinitis PigmentosaAlström syndromeRetinopathyPolycystic Ovary SyndromeAmerican journal of medical genetics
researchProduct

Homocysteine and MTHFR C677T polymorphism in children and adolescents with psychotic and mood disorders

2013

High level of homocysteine (Hcy) is risk factor of schizophrenia and mood disorders.The aim was to detect a serum level of Hcy, examine the associations between the level of Hcy, methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism and clinical properties for patients with schizophrenia, mood disorders and in a control group.There were 88 patients with schizophrenia, 28 with affective disorders and 94 from the control group. The Hamilton Anxiety Scale (HAM-A) was performed to study anxiety, the Hamilton Depression Scale (HAM-D) to study depression and the Brief Psychiatric Rating Scale (BPRS) to study severity of schizophrenia. The level of Hcy was stated by isocratic high-pe…

Malemedicine.medical_specialtyAdolescentHomocysteinePolymerase Chain Reactionbehavioral disciplines and activitieschemistry.chemical_compoundmental disordersBrief Psychiatric Rating ScalemedicineHumansRisk factorChildPsychiatryHomocysteineMethylenetetrahydrofolate Reductase (NADPH2)DNA PrimersPolymorphism GeneticBase SequencebiologyMood DisordersCase-control studymedicine.diseaseVitamin B 12Psychiatry and Mental healthchemistryMood disordersSchizophreniaCase-Control StudiesMethylenetetrahydrofolate reductaseSchizophreniabiology.proteinAnxietyFemalemedicine.symptomPsychologyNordic Journal of Psychiatry
researchProduct

Jaw cysts at children and adolescence : a single-center retrospective study of 152 cases in southern Bulgaria

2010

One hundred fifty two cysts of the upper and lower jaw were examined at patients up to 18 years old treated in the Clinics of Maxillo-Facial Surgery, University Hospital, Plovdiv, Bulgaria for the period 1998 - 2007. Patients were distributed in four age groups (up to 4 years old, from 5 to 9 years old, from 10 to 14 years old, from 15 to 18 years old). Both sexes were constantly affected (52% male, 48% female). The biggest number cystic lesions were found in the third age group (48.7%). The mandible was preferable localization of the lesions (69.7%). Dentigerous cysts predominated (61.8%) - more affected was third age group (31.6%). Radicular cysts were observed two times less (31.6%) - mo…

Malemedicine.medical_specialtyAdolescentJaw CystsOne Hundred FiftySingle CenterCystic lesionAge groupsmedicineHumansBulgariaChildGeneral DentistryRetrospective StudiesSurgical approachbusiness.industryIntraoral approachInfantRetrospective cohort studyUniversity hospital:CIENCIAS MÉDICAS [UNESCO]SurgeryOtorhinolaryngologyChild PreschoolUNESCO::CIENCIAS MÉDICASSurgeryFemalebusiness
researchProduct

Laparoscopic removal of mullerian duct remnants in boys

2003

Abstract: Purpose: Mullerian duct remnants (MDRs) are present in a male pseudohermaphroditic form characterized by failure of the mullerian duct to regress due to insufficient production or peripheral action of mullerian inhibiting substance. The MDR can be asymptomatic but it often results in infections, stones and voiding troubles. Furthermore, it may develop into a neoplasm. Therefore, surgery is mandatory for large MDRs and symptomatic patients. Laparoscopic removal is described. Materials and Methods: Six males were treated from February 1998 to February 2003. Age at surgery was between 3 and 18 years (mean 8.6). All patients showed severe hypospadias and 2 had mixed gonadal dysgenesis…

Malemedicine.medical_specialtyAdolescentMullerian DuctsUrologyurogenital abnormalitiesIliac fossaAsymptomaticmedicineHumansLaparoscopyChildMullerian Ductsmedicine.diagnostic_testbusiness.industrymullerian ductCystoscopymedicine.diseaseurethra testis mullerian ducts laparoscopy urogenital abnormalitiesEndoscopySurgerymedicine.anatomical_structureUrethraHypospadiasChild PreschoolUrologic Surgical ProceduresLaparoscopymedicine.symptomurethrabusiness
researchProduct

Retinol-Binding Protein 4 Levels Are Associated with Measures of Liver and Renal Function and Oxidant/Antioxidant Status in Obese Children

2013

Serum retinol-binding protein 4 (RBP4) has been proposed as a metabolic risk factor in obesity. We found that RBP4 levels also were associated with liver enzymes and cystatin C. Oxidant stress is a significant feature in obese children with greater values of RBP4 that can mediate the development of comorbidities.

Malemedicine.medical_specialtyAdolescentRenal functionKidneyKidney Function TestsAntioxidantschemistry.chemical_compoundLiver Function TestsInternal medicinemedicineHumansObesityChildRetinol binding protein 4biologybusiness.industryMetabolic riskOxidant antioxidantGlutathioneOxidantsmedicine.diseaseObesityOxidative StressEndocrinologyLiverchemistryCystatin CPediatrics Perinatology and Child Healthbiology.proteinFemaleCystatinbusinessRetinol-Binding Proteins PlasmaThe Journal of Pediatrics
researchProduct

The recurrence of odontogenic keratocysts in pediatric patients is associated with clinical findings of Gorlin-Goltz Syndrome

2019

Background Odontogenic keratocyst (OKC) is an odontogenic developmental cyst that presents distinct clinical behavior. This lesion has been described as dental cysts with keratinization since the 1930s, however the term "OKC" was established in 1956. This study aims to determine the frequency and features of OKC in children aged 0 to 14 years in an oral pathology service in Brazil. Material and Methods A retrospective study was performed to review cases of OKC in children diagnosed between 1986 and 2017. Clinical data were evaluated from medical records (gender, race, age, anatomical location, treatment, radiographic findings and follow-up). Results Ninety-seven cases of OKC were diagnosed …

Malemedicine.medical_specialtyAdolescentmedicine.medical_treatmentBasal Cell Nevus SyndromeAsymptomaticRecurrenceOral and maxillofacial pathologyHumansMedicineKeratocystChildGeneral DentistryRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchInfant NewbornInfantBasal Cell Nevus SyndromeRetrospective cohort study:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDermatologyCurettagestomatognathic diseasesOtorhinolaryngologyEl NiñoChild PreschoolUNESCO::CIENCIAS MÉDICASOdontogenic CystsFemaleSurgeryNeoplasm Recurrence Localmedicine.symptomDifferential diagnosisbusinessBrazilMedicina Oral Patología Oral y Cirugia Bucal
researchProduct

Alpha-adrenergic modulation of glutathione metabolism in isolated rat hepatocytes.

1988

Glutathione metabolism was studied in isolated hepatocytes from 48-h starved rats. Phenylephrine (10 microM, final concentration) was incubated in the presence of a mixture of L-glutamine, glycine, L-serine, and L-methionine (at 10 times their normal plasma concentration). Alpha-adrenergic stimulation provoked a decrease in glutathione (GSH) synthesis. This effect was accompanied by an enhanced efflux of glutathione from the cells. Phenylephrine stimulated the rate of glutathione disulfide (GSSG) formation; however, this effect was clearly insufficient to explain the disappearance of GSH. Our results suggest that the decrease in cellular GSH levels observed under conditions of shock, stress…

Malemedicine.medical_specialtyAdrenergic receptorPhysiologyEndocrinology Diabetes and MetabolismStimulationIn Vitro Techniqueschemistry.chemical_compoundPhenylephrineReference ValuesPhysiology (medical)Internal medicinemedicineAnimalsCysteineAmino AcidsPhenylephrineGlutathione DisulfideRats Inbred StrainsGlutathioneMetabolismGlutathioneRatsKineticsEndocrinologymedicine.anatomical_structurechemistryLiverHepatocyteGlutathione disulfideEffluxmedicine.drugThe American journal of physiology
researchProduct