Search results for "D2"

showing 10 items of 2418 documents

Treatment of Combined Dairy and Domestic Wastewater with Constructed Wetland System in Sicily (Italy). Pollutant Removal Efficiency and Effect of Veg…

2021

Dairy wastewater (DWW) contains large amounts of mineral and organic compounds, which can accumulate in soil and water causing serious environmental pollution. A constructed wetland (CW) is a sustainable technology for the treatment of DWW in small-medium sized farms. This paper reports a two-year study on the performance of a pilot-scale horizontal subsurface flow system for DWW treatment in Sicily (Italy). The CW system covered a total surface area of 100 m2 and treated approximately 6 m3 per day of wastewater produced by a small dairy farm, subsequent to biological treatment. Removal efficiency (RE) of the system was calculated. The biomass production of two emergent macrophytes was dete…

dairy wastewaterlcsh:Hydraulic engineeringhorizontal sub-surface flow system0208 environmental biotechnologyGeography Planning and DevelopmentBiomassEnvironmental pollution02 engineering and technology010501 environmental sciencesAquatic Science01 natural sciencesBiochemistryremoval efficiencylcsh:Water supply for domestic and industrial purposeslcsh:TC1-978medicineSubsurface flow0105 earth and related environmental sciencesWater Science and TechnologyPollutantlcsh:TD201-500Environmental engineeringplant growthSeasonalitymedicine.diseaseSettore AGR/02 - Agronomia E Coltivazioni Erbacee020801 environmental engineeringMacrophyteWastewaterConstructed wetlandEnvironmental scienceWater
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Unusual Regioselectivity in the Opening of Epoxides by Carboxylic Acid Enediolates

2008

Addition of carboxylic acid dianions appears to be a potential alternative to the use of aluminium enolates for nucleophilic ring opening of epoxides. These conditions require the use of a sub-stoichiometric amount of amine (10% mol) for dianion generation and the previous activation of the epoxide with LiCl. Yields are good, with high regioselectivity, but the use of styrene oxide led, unexpectedly, to a mixture resulting from the attack on both the primary and secondary carbon atoms. Generally, a low diastereoselectivity is seen on attack at the primary center, however only one diastereoisomer was obtained from attack to the secondary carbon of the styrene oxide.

diastereoselectivity.Carboxylic acidCarboxylic AcidsPharmaceutical ScienceEpoxideMedicinal chemistryAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundLactoneslcsh:Organic chemistryNucleophileStyrene oxideDrug DiscoveryOrganic chemistryPhysical and Theoretical Chemistrylithium chloridechemistry.chemical_classificationNucleophilic additionCommunicationOrganic ChemistryDiastereomerRegioselectivitydiastereoselectivitynucleophilic additionchemistryChemistry (miscellaneous)regioselectivityMolecular MedicineEpoxy CompoundsAmine gas treatingMolecules
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Polytetrafluoroethylene Films in Rigid Polyurethane Foams' Dielectric Permittivity Measurements with a One-Side Access Capacitive Sensor.

2021

As a non-metallic composite material, widely applied in industry, rigid polyurethane (PUR) foams require knowledge of their dielectric properties. In experimental determination of PUR foams’ dielectric properties protection of one-side capacitive sensor’s active area from adverse effects caused by the PUR foams’ test objects has to be ensured. In the given study, the impact of polytetrafluoroethylene (PTFE) films, thickness 0.20 mm and 0.04 mm, in covering or simulated coating the active area of one-side access capacitive sensor’ electrodes on the experimentally determined true dielectric permittivity spectra of rigid PUR foams is estimated. Penetration depth of the low frequency excitation…

dielectric permittivityMaterials sciencePolymers and PlasticsCapacitive sensing02 engineering and technologyDielectricengineering.materialLow frequency01 natural sciencesArticlelcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistryCoatingone-side access0103 physical sciencesComposite materialPenetration depthPolyurethane010302 applied physicsPolytetrafluoroethylenepolyurethane foamscapacitive sensorGeneral Chemistryprotectionpolyurethane foams; dielectric permittivity; capacitive sensor; one-side access; adverse effects; protection; PTFE films021001 nanoscience & nanotechnologychemistryPTFE filmsElectrodeadverse effectsengineering0210 nano-technologyPolymers
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Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes

2021

Incorporation of fluorine into organic molecules is a well-established strategy in the design of advanced materials, agrochemicals, and pharmaceuticals. Among numerous modern synthetic approaches, functionalization of unsaturated bonds with simultaneous addition of trifluoromethyl group along with other substituents is currently one of the most attractive methods undergoing wide-ranging development. In this review article, we discuss the most significant contributions made in this area during the last decade (2012−2021). The reactions reviewed in this work include chloro-, bromo-, iodo-, fluoro- and cyano-trifluoromethylation of alkenes and alkynes.

difunctionalizationPharmaceutical Sciencechemistry.chemical_elementReviewAdvanced materialsalkynesAnalytical ChemistryOrganic moleculeschemistry.chemical_compoundQD241-441Unsaturated bondsDrug DiscoveryPhysical and Theoretical ChemistryTrifluoromethylalkenesTrifluoromethylationcyanotrifluoromethylationOrganic ChemistryCombinatorial chemistryhalotrifluoromethylationchemistryAlquensChemistry (miscellaneous)Fluorinesynthetic methodsMolecular MedicineQuímica orgànica
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Protocol: A literature review about the use of crowdsourcing in educational environments

2016

<p>The objective with the protocol described in this paper is to review the existing literature in relation to the implementation of crowdsourcing in educational environments. It seeks to give answer to 4 questions. First, it seeks to answer the question of which kind of crowdsourcing initiatives are more appropriate to be used for educational activities. In second place it’s important to find out whether there is any particular discipline in which crowdsourcing, by its nature, can be applied more naturally. Third, it seeks to identify which factors influence both positively and negatively in the teaching/learning experience using crowdsourcing. Finally, the last question to answer, t…

educationKnowledge managementlcsh:Management. Industrial managementlcsh:Personnel management. Employment managementRelation (database)business.industrylcsh:HF5549-5549.5collective intelligencePublic relationsCrowdsourcinginnovationLearning experiencelcsh:HD28-70crowdsourcingPsychologybusinessProtocol (object-oriented programming)WPOM : Working Papers on Operations Management
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Special Issue: Improvements for Resveratrol Efficacy

2017

International audience; Resveratrol is a well-known phenolic stilbene because of its presence in several edible plants and its proposed properties that are beneficial to human health [...].

educationPharmaceutical Sciencemacromolecular substancesResveratrol010402 general chemistry01 natural sciences[ CHIM ] Chemical SciencesAnalytical Chemistrylcsh:QD241-441Human healthchemistry.chemical_compoundlcsh:Organic chemistryStilbenesDrug DiscoveryHumansMedicine[CHIM]Chemical SciencesPhysical and Theoretical ChemistryCyclodextrins010405 organic chemistrybusiness.industryOrganic Chemistryfood and beverages3. Good health0104 chemical sciencesBiotechnologyEditorialn/achemistryResveratrolChemistry (miscellaneous)LiposomesEdible plantsMolecular MedicinebusinessMolecules
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Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Pol…

2020

The brain, which is a cholesterol-rich organ, can be subject to oxidative stress in a variety of pathophysiological conditions, age-related diseases and some rare pathologies. This can lead to the formation of 7-ketocholesterol (7KC), a toxic derivative of cholesterol mainly produced by auto-oxidation. So, preventing the neuronal toxicity of 7KC is an important issue to avoid brain damage. As there are numerous data in favor of the prevention of neurodegeneration by the Mediterranean diet, this study aimed to evaluate the potential of a series of polyphenols (resveratrol, RSV

eicosapentaenoic acidPharmaceutical ScienceResveratrolDiet Mediterraneanmedicine.disease_causequercetinAnalytical ChemistryMicechemistry.chemical_compound0302 clinical medicineDrug Discoveryoxidative stressKetocholesterolsNeuronschemistry.chemical_classification0303 health sciencesCell Deathfood and beveragesdocosahexaenoic acidEicosapentaenoic acidMitochondriaBiochemistryChemistry (miscellaneous)Docosahexaenoic acid030220 oncology & carcinogenesisMolecular Medicineα-linolenic acidN2a cellsArticlelcsh:QD241-44103 medical and health sciencesresveratrol.lcsh:Organic chemistryCell Line TumorMediterranean dietFatty Acids Omega-3medicineAnimalsPropidium iodidePhysical and Theoretical Chemistry7-ketocholesterol030304 developmental biologyapigeninReactive oxygen speciesOrganic ChemistryNeurotoxicityPolyphenolsmedicine.diseaseOleic acidoleic acidchemistryReactive Oxygen SpeciesOxidative stressMolecules
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Automātiska teksta konspektēšana izmantojot jēdzientelpu

2016

Šobrīd pasaulē ir vērojams milzīgs informācijas daudzuma pieaugums un ir arvien grūtāk iepazīties ar šo informāciju. Automātiskas teksta konspektēšanas mērķis ir spēt pārveidot lielu tekstuālas informācijas daudzumu īsākā formātā, kurš spēj saglabāt oriģinālā teksta svarīgāko informāciju. Viena no metodēm kā automātiski konspektēt tekstu ir izvēlēties svarīgākos teikumus no teksta. Mērķis ir izvēlēties teikumus tā, lai tajos esošā informācija savstarpēji nepārklājas, kā arī nosedz pietiekamu daļu no konspektējamā teksta. Lai to izdarītu ir jāsalīdzina teikumu ietvertās informācijas līdzīgums. Jēdzientelpa ir moderns rīks, ar kura palīdzību var noteikt vārdu nozīmi un līdzību ar citiem vārdi…

ekstraktīva konspektēšanajēdzientelpaDatorzinātneword2vecTF-IDF
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De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome

2014

Activating mutations in genes encoding phosphatidylinositol 3-kinase (PI3K)-AKT pathway components cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH, OMIM 603387)(1-3). Here we report that individuals with MPPH lacking upstream PI3K-AKT pathway mutations carry de novo mutations in CCND2 (encoding cyclin D2) that are clustered around a residue that can be phosphorylated by glycogen synthase kinase 313 (GSK-3 beta)(4). Mutant CCND2 was resistant to proteasomal degradation in vitro compared to wild-type CCND2. The PI3K-AKT pathway modulates GSK-3 beta activity(4), and cells from individuals with PIK3CA, PIK3R2 or AKT3 mutations showed similar CCND2 accumulation. CCND…

endocrine systemBlotting WesternMolecular Sequence DataMutantMedizinBiologymedicine.disease_causeArticleAKT3Mice03 medical and health sciences0302 clinical medicineCyclin D2GSK-3GeneticsmedicineAnimalsCyclin D2HumansAbnormalities MultipleExomeMegalencephalyPI3K/AKT/mTOR pathway030304 developmental biology0303 health sciencesMutationBase SequenceSequence Analysis DNASyndromeCell cyclemedicine.diseaseImmunohistochemistryMolecular biologyMegalencephalyMalformations of Cortical DevelopmentPolydactylyElectroporationHEK293 CellsBromodeoxyuridineMicroscopy FluorescenceMutagenesis Site-DirectedFemale030217 neurology & neurosurgeryHydrocephalusNature Genetics
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Unexplored nucleophilic ring opening of aziridines.

2010

The reactivity of dianions of carboxylic acids towards aziridines has been studied. Although, a similar reactivity to that of enolates from ketones, esters or amides has been observed, the method directly yields g-aminoacids in one step. The method is complementary of previous results of enenediolate reactivity with other electrophiles. A comparative study with the reactivity of this enediolates with epoxides is included.

enediolatePharmaceutical ScienceRing (chemistry)ArticleAnalytical Chemistrylcsh:QD241-441lcsh:Organic chemistryNucleophileDrug DiscoveryOrganic chemistryReactivity (chemistry)Physical and Theoretical ChemistryAmino AcidsChemistryOrganic Chemistryγ-aminoacidsRegioselectivityg-aminoacidsKetonesdiastereoselectivityChemistry (miscellaneous)aziridinesregioselectivityElectrophileMolecular MedicineEpoxy CompoundsMolecules (Basel, Switzerland)
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