Search results for "DM"

showing 10 items of 8932 documents

"Table 5" of "Measurement of dielectron production in central Pb-Pb collisions at $\sqrt{{\textit{s}}_{\mathrm{NN}}}$ = 2.76 TeV"

2018

Dielectron invariant-mass spectrum measured in central Pb-Pb collisions for the transverse-momentum interval 1.0 < $p_{\rm T,ee}$ < 2.0 GeV/$c. The statistical and systematic uncertainties of the data are represented by vertical bars and boxes.

2760.0DN/DMHigh Energy Physics::ExperimentPB PB --> E+ E- XNuclear ExperimentDielectron yield (dN/dm)
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"Table 6" of "Measurement of dielectron production in central Pb-Pb collisions at $\sqrt{{\textit{s}}_{\mathrm{NN}}}$ = 2.76 TeV"

2018

Dielectron invariant-mass spectrum measured in central Pb--Pb collisions for the transverse-momentum interval 2.0 < $p_{\rm T,ee}$ < 4.0 GeV/$c. The statistical and systematic uncertainties of the data are represented by vertical bars and boxes.

2760.0DN/DMHigh Energy Physics::ExperimentPB PB --> E+ E- XNuclear ExperimentDielectron yield (dN/dm)
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"Table 12: Cross-section limits lepton specific tanb 1" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in…

2018

The cross section times BR(A->ZH) times BR(H->bb) limits for an A boson in the lepton specific, tanbeta 1, 2HDM. For each signal point, characterised by the mass pair (mA, mH), two limits are provided, the observed and the expected. The correct width as predicted by this particular parameter choice of the 2HDM is used. For lepton specific only gluon-gluon fusion is used and the nb=2 category only.

2HDMHIGGS --> BQ BQBAR13000.0CLSHigh Energy Physics::Phenomenologycross section limitsZ0 --> MU+ MU-Z0 --> E+ E-P P --> HIGGSgluon-gluon fusionHigh Energy Physics::ExperimentHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 14: Cross-section limits lepton specific tanb 3" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in…

2018

The cross section times BR(A->ZH) times BR(H->bb) limits for an A boson in the lepton specific, tanbeta 3, 2HDM. For each signal point, characterised by the mass pair (mA, mH), two limits are provided, the observed and the expected. The correct width as predicted by this particular parameter choice of the 2HDM is used. For lepton specific only gluon-gluon fusion is used and the nb=2 category only.

2HDMHIGGS --> BQ BQBAR13000.0CLSHigh Energy Physics::Phenomenologycross section limitsZ0 --> MU+ MU-Z0 --> E+ E-P P --> HIGGSgluon-gluon fusionHigh Energy Physics::ExperimentHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 13: Cross-section limits lepton specific tanb 2" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in…

2018

The cross section times BR(A->ZH) times BR(H->bb) limits for an A boson in the lepton specific, tanbeta 2, 2HDM. For each signal point, characterised by the mass pair (mA, mH), two limits are provided, the observed and the expected. The correct width as predicted by this particular parameter choice of the 2HDM is used. For lepton specific only gluon-gluon fusion is used and the nb=2 category only.

2HDMHIGGS --> BQ BQBAR13000.0CLSHigh Energy Physics::Phenomenologycross section limitsZ0 --> MU+ MU-Z0 --> E+ E-P P --> HIGGSgluon-gluon fusionHigh Energy Physics::ExperimentHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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Chiral Serum Pharmacokinetics of 4-Fluoroamphetamine after Controlled Oral Administration

2021

Abstract Over the last two decades, misuse of 4-fluoroamphetamine (4-FA) became an emerging issue in many European countries. Stimulating effects last for 4–6 hours and can impact psychomotor performance. The metabolism of amphetamine-type stimulants is stereoselective and quantification of (R)- and (S)-enantiomers has been suggested for assessing time of use. To date, no data on enantioselective pharmacokinetics is available for 4-FA in serum samples. An enantioselective liquid chromatography−tandem mass spectrometry (LC–MS-MS) method was developed using a chiral Phenomenex® Lux 3 μm AMP column. Validation of the method showed satisfactory selectivity, sensitivity, linearity (0.5–250 ng/mL…

3SAMPLESHealth Toxicology and MutagenesisNETHERLANDSAdministration OralAMPHETAMINEMETABOLISMMETHAMPHETAMINEToxicology01 natural sciencesSTEREOSELECTIVE PHARMACOKINETICSAnalytical Chemistry03 medical and health sciences4-Fluoroamphetamine0302 clinical medicinePharmacokineticsTandem Mass SpectrometryOral administrationmedicineHumansEnvironmental ChemistryIngestion030216 legal & forensic medicineChemical Health and SafetyChromatography34-METHYLENEDIOXYMETHAMPHETAMINEChemistryAmphetamines010401 analytical chemistryTRANSPORTERStereoisomerism4-METHYLENEDIOXYMETHAMPHETAMINESerum samples0104 chemical sciencesStereoselectivityFLUOROAMPHETAMINEEnantiomerPSYCHOACTIVE SUBSTANCES NPSTime of useChromatography Liquidmedicine.drugJournal of Analytical Toxicology
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Co-Loading of Ascorbic Acid and Tocopherol in Eudragit-Nutriosomes to Counteract Intestinal Oxidative Stress

2019

The present study aimed at developing a new vesicular formulation capable of promoting the protective effect of ascorbic acid and tocopherol against intestinal oxidative stress damage, and their efficacy in intestinal wound healing upon oral administration. A pH-dependent copolymer (Eudragit&reg

3003AntioxidantVitamina CVitamina Emedicine.medical_treatmentNeuroimmunologyPhospholipidPharmaceutical Sciencelcsh:RS1-441CicatritzacióWound healingNutriose02 engineering and technologymedicine.disease_causeEudragitArticlelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compoundOral administrationmedicinePhospholipid vesiclesVitamin ETocopherolVitamin C030304 developmental biology0303 health sciencesIntestinsChromatographyVesiclePrebiotic021001 nanoscience & nanotechnologyAscorbic acidIntestinal wound healingNeuroimmunologiaIntestineschemistryAntioxidant; Eudragit; Intestinal wound healing; Nutriose; Phospholipid vesicles; 3003Antioxidant0210 nano-technologyOxidative stress
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Buccal drug delivery: what's new and what does the future hold?

2014

The buccal mucosa is the stratified squamous epithelial tissue inside lining of the cheeks. It is a favorable site of drug absorption since the tissue is non-keratinized, relatively immobile and strongly supplied with blood by a dense capillary-vessel network; moreover, it is highly tolerant to allergens, resistant to potentially harmful agents and has a relatively low enzymatic activity. The tissue consents quick onset of effect, offers an easily accessible and generally well-accepted site for drug delivery, is a useful route of administration in patients in an unconscious state (e.g., when swallowing is impaired), and is suitable for retentive dosage forms of administration. Buccal mucosa…

3003Drugmedia_common.quotation_subjectChemistry PharmaceuticalPharmaceutical ScienceDentistryPharmacologyDosage formRoute of administrationDrug Delivery SystemsPharmacokineticsMucositisMedicineAnimalsHumansBuccal dosage formmedia_commonDosage FormsDrug Carriersbusiness.industryLocoregional/systemic treatmentMedicine (all)Mouth MucosaAdministration BuccalTransmucosal deliveryBuccal administrationmedicine.diseaseBioavailabilityPharmaceutical PreparationsSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoDrug deliveryBuccal mucosaDiffusion of InnovationbusinessForecastingTherapeutic delivery
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COMBINATION OF ARGAN OIL AND PHOSPHOLIPIDS FOR THE DEVELOPMENT OF AN EFFECTIVE LIPOSOME-LIKE FORMULATION ABLE TO IMPROVE SKIN HYDRATION AND ALLANTOIN…

2016

Allantoin is traditionally employed in the treatment of skin ulcers and hypertrophic scars. In the present work, to improve its local deposition in the skin and deeper tissues, allantoin was incorporated in conventional liposomes and in new argan oil enriched liposomes. In both cases, obtained vesicles were unilamellar, as confirmed by cryo-TEM observation, but the addition of argan oil allowed a slight increase of the mean diameter (∼130nm versus ∼85nm). The formulations, especially those containing argan oil, favoured the allantoin accumulation in the skin, in particular in the dermis (∼8.7μg/cm(2)), and its permeation through the skin (∼33μg/cm(2)). The performances of vesicles as skin d…

3003Pig skinfood.ingredientSwineChemistry PharmaceuticalSkin AbsorptionPharmaceutical ScienceArgan oil02 engineering and technologyAdministration Cutaneous030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compoundDrug Delivery Systems0302 clinical medicineAllantoinfoodDermisElastic ModulusSkin rheologymedicineAnimalsPlant OilsAllantoinSofteningPhospholipidsSkinDrug CarriersLiposomeChromatographyintegumentary systemChemistryVesicleLiposomes; Argan oil; Phospholipids; Pig skin; Turbiscan lab; Skin rheology; Skin hydrationPermeation021001 nanoscience & nanotechnologyTurbiscan labmedicine.anatomical_structureSkin hydrationArgan oilLiposomesDermatologic Agents0210 nano-technologyDrug carrierargan oil; liposomes; phospholipids; pig skin; skin hydration; skin rheology; turbiscan lab; 3003
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Nanodesign of new self-assembling core-shell gellan-transfersomes loading baicalin and in vivo evaluation of repair response in skin

2017

Gellan nanohydrogel and phospholipid vesicles were combined to incorporate baicalin in new self-assembling core-shell gellan-transfersomes obtained by an easy, scalable method. The vesicles were small in size (~107 nm) and monodispersed (P.I. ≤ 0.24), forming a viscous system (~24 mPa/s) as compared to transfersomes (~1.6 mPa/s), as confirmed by rheological studies. Gellan was anchored to the bilayer domains through cholesterol, and the polymer chains were distributed onto the outer surface of the bilayer, thus forming a core-shell structure, as suggested by SAXS analyses. The optimal carrier ability of core-shell gellan-transfersomes was established by the high deposition of baicalin in th…

3003SwinePharmaceutical ScienceMedicine (miscellaneous)02 engineering and technology01 natural sciencesMicechemistry.chemical_compoundDrug Delivery Systemsmaterials science (all)skin deliveryGeneral Materials ScienceSkinchemistry.chemical_classificationSkin repairSmall-angle X-ray scatteringBilayerVesicleAnti-Inflammatory Agents Non-SteroidalPolysaccharides BacterialPolymer021001 nanoscience & nanotechnologymedicine.anatomical_structureMolecular MedicineFemale0210 nano-technologytransfersomesSkin AbsorptionBiomedical EngineeringgellanBioengineeringAdministration Cutaneous010402 general chemistryIn vivo studiesDermisIn vivoSAXS analysismedicineAnimalsgellan; In vivo studies; rheological studies; SAXS analysis; skin delivery; transfersomes; bioengineering; medicine (miscellaneous); molecular medicine; biomedical engineering; materials science (all); 3003rheological studiesFlavonoidsInflammationWound Healing0104 chemical sciencesAnimals NewbornchemistryLiposomesBiophysicsNanoparticlesBaicalin
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