Search results for "DM"

Treadmill and Running Speed Effects on Acceleration Impacts: Curved Non-Motorized Treadmill vs. Conventional Motorized Treadmill

2021

An increase in the popularity of running can be seen over the last decades, with a large number of injuries on it. Most of the running injuries are related to impact accelerations and are due to overuse. In order to reduce the risk of injury or to improve performance and health new treadmill designs have been created, as it can be the curved non-motorized treadmill. The aim of this study was to analyse impact accelerations, spatio-temporal parameters and perceptual differences while running on curved non-motorized treadmill (cNMT) compared to motorized treadmill (MT) at different speeds. Therefore, 27 recreational runners completed two tests consisting of 10 min warm-up and three bouts of 8…

General therapeutic guidelines

2017

There are currently no methods available that have been proven to promote or accelerate regenerative processes in nerves. This lack often leads to disappointment for both patient and physician.

Therapeutic dosages of oral or transdermal estradiol did not modify sCD40L levels in postmenopausal women.

2008

The CD40/CD40L system is considered a crucial modulator of the inflammatory process underlying the progression and complication of atheroma plaques. The soluble fraction of CD40L (sCD40L) is a reliable indicator of the CD40/CD40L system. Our purpose was to investigate whether a therapeutic dose of estradiol, by either the oral or the transdermal route, was associated with changes in circulating levels of sCD40L. Forty-seven women completed a 4-week course of treatment with either oral estradiol valerate (2 mg/day, 20 women) or transdermal estradiol (50 microg/day, 27 women). Serum levels of sCD40L were measured by conventional enzyme-linked immunosorbent assay. Oral, but not transdermal est…

Cocaine and MDMA Induce Cellular and Molecular Changes in Adult Neurogenic Systems: Functional Implications

2011

The capacity of the brain to generate new adult neurons is a recent discovery that challenges the old theory of an immutable adult brain. A new and fascinating field of research now focuses on this regenerative process. The two brain systems that constantly produce new adult neurons, known as the adult neurogenic systems, are the dentate gyrus (DG) of the hippocampus and the lateral ventricules/olfactory bulb system. Both systems are involved in memory and learning processes. Different drugs of abuse, such as cocaine and MDMA, have been shown to produce cellular and molecular changes that affect adult neurogenesis. This review summarizes the effects that these drugs have on the adult neurog…

Chronic oral haloperidol and clozapine in rats: A behavioral evaluation.

1999

The present study evaluated chronic oral treatment of rats with haloperidol or clozapine. Drugs were given in the drinking water for a 23-day period . Rat behavior was analyzed once a week in an open field. Rats ingested either 1.7 mg/kg haloperidol or 40 mg/kg clozapine daily. Blood serum analysis revealed concentrations of 6 ng/ml for haloperidol and 22 ng/ml for clozapine at the end of the treatment. Haloperidol decreased overall activity from the onset of treatment. Clozapine showed similar effects only on the last test day. Control animals showed a slight habituation in exploration-related parameters. In conclusion, these results indicate that oral drug administration through the drink…

Quo vadis SANEPID? A cross-country analysis of public health reforms in 10 post-Soviet states

2010

Abstract Background The public health systems of the post-Soviet states have evolved from the san-epid system, which dominated public health practice throughout the former Soviet Union. Since independence, reforms have taken different directions. This article provides a cross-country comparison of public health reform processes and contents in 10 post-Soviet states. Methods The study is descriptive and comparative, based on a literature review of the major health databases, the Health Systems in Transition (HiT) volumes and grey literature. Search terms included terms on public health, the san-epid services and organizational reforms in one or several post-Soviet states. Results Public heal…

Association between silent atrial fibrillation and heart failure after acute myocardial infarction

2013

Right heart dysfunction and readmission risk across left ventricular ejection fraction status in patients with acute heart failure

2021

Abstract Background Right heart dysfunction (RHD) parameters, such as right ventricular to pulmonary artery uncoupling or significant tricuspid regurgitation (TR) are increasingly important in heart failure (HF), especially in patients with preserved ejection fraction. In this study, we aimed to evaluate the association of advanced RHD with the risk of recurrent admissions across the spectrum of left ventricular ejection fraction (LVEF). Methods We included 3,383 consecutive patients discharged for acute HF (AHF). Of them, in 1,435 (42.4%) pulmonary artery systolic pressure (PASP) could not be accurately measured, leaving a final sample size of 1,948 patients. Advanced RHD was defined as th…

Effect of β-cryptoxanthin plus phytosterols on cardiovascular risk and bone turnover markers in post-menopausal women: a randomized crossover trial.

2014

Abstract Background and aim Post-menopausal women are at higher risk of cardiovascular disease and bone demineralization. Phytosterols (PS) may be used for hypercholesterolemia in some groups and β-cryptoxanthin (β-Cx) displays a unique anabolic effect on bone. Our aim was to assess the changes in cardiovascular and bone turnover markers from the oral intake of β-Cx and PS in post-menopausal women. Methods and results A randomized, double-blind, crossover study with β-Cx (0.75 mg/day) and PS (1.5 g/day), single and combined, was performed in 38 postmenopausal women. Diet was supplemented with 1 × 250 mL milk-based fruit drink/day for 4 weeks with a wash-out period of 4-weeks in between. Ser…

Cultural approach to the perception of risk: analysing concern about the siting of a high-level nuclear waste facility in Finland

1999

A study of local residents' attitudes toward the siting of a high-level nuclear waste facility in Finland was undertaken in three municipalities (Eurajoki, Kuhmo and Aänekoski) that are being considered possible host communities for the facility. The results of the survey show that opposition to the facility is quite strong in two of the three municipalities, while in the third a polarization of opinions into two opposing camps is evident. The size, social structure and substance of the local opposition and support are analysed. The thesis of the paper is that in order to understand different opinions about the facility, one must understand the cultural logic of risk perception. People eva…