Search results for "DOMAIN"

showing 10 items of 2485 documents

Dire institutionnel et espaces de langage - le cas de l'Algérie - Essai d'une sémio-didactique

1992

This thesis is 1) an discourse analysis of the institution' texts (Algeria, in the eighties) + analysis of the young people in secondary school (part I) ; 2) a semiotic analysis of spaces in Algeria (country, village, secondary school). The results : we showed many contraints in a collective speech, through 2 dominant themas : time, action ; and 2 recessive themas : subject (speaker), mirror. So, education and didactic perspective are useful.

peoplespaceéducation[ OTHER ] domain_other[OTHER]domain_otherspeakingpeuple[SHS]Humanities and Social Sciencesfrançais langue non premièreinstitutionAlgérieparolesemioticsespaceAlgeriasémiotique[ SHS ] Humanities and Social Sciences[OTHER] domain_otherdiscourse[SHS] Humanities and Social Sciencesfrench for non nativesdiscours
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Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors

2012

Herein we report the synthesis of a set of constrained peptidomimetics endowed with an electrophilic vinyl ester warhead and structurally related to a previously identified lead compound, a potent and irreversible inhibitor of falcipain-2 (FP-2). FP-2 is the main hemoglobinase of the malaria parasite P. falciparum. The new compounds were evaluated for their inhibition against FP-2, and the results were rationalized on the basis of docking experiments. These studies underscore the pivotal role of both the ester function at the P1' site and the trifluoromethyl group of the P3 side chain in determining the correct orientation of the Michael acceptor warhead in the catalytic site, and as a cons…

peptidomimeticdMolecular modelPeptidomimeticStereochemistryPlasmodium falciparumVinyl esterBiochemistrycysteine proteasesfalcipain-2 inhibitorsAntimalarialschemistry.chemical_compoundCatalytic DomainDrug DiscoverySide chainHumansEnzyme InhibitorsMalaria FalciparumGeneral Pharmacology Toxicology and PharmaceuticsPharmacologyTrifluoromethylOrganic Chemistrydocking studiescysteine proteases; peptidomimeticd; docking studies; falcipain-2 inhibitorsMolecular Docking SimulationCysteine EndopeptidaseschemistryDocking (molecular)Michael reactionMolecular MedicinePeptidomimeticsLead compoundChemMedChem
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<p>Barriers and enablers to the implementation of perioperative hypothermia prevention practices from the perspectives of the multidisciplinary…

2019

Judy Munday,1,2 Alana Delaforce,1,3 Gillian Forbes,4 Samantha Keogh11School of Nursing and Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, QLD 4059, Australia; 2Department of Health and Nursing Science, University of Agder, Grimstad, Norway; 3Clinical Governance Unit, Mater Health, South Brisbane, QLD 4101, Australia; 4Department of Clinical, Educational and Health Psychology, UCL Centre for Behaviour Change, London WC1E 6BT, UKPurpose: Inadvertent perioperative hypothermia is a significant problem for surgical patients globally, and is associated with many detrimental side-effects. Despite the availability of rigorously developed internatio…

perioperative hypothermiaPerioperative nursingJournal of Multidisciplinary Healthcare030503 health policy & servicesBehavior changePsychological interventionContext (language use)General MedicinePerioperativeAuditCOM-Btemperature management03 medical and health sciences0302 clinical medicineNursingbehaviour change wheel030212 general & internal medicineTheoretical Domains Framework0305 other medical sciencePsychologymultidisciplinaryGeneral NursingOriginal ResearchSocial influenceQualitative researchJournal of Multidisciplinary Healthcare
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Dependence of effective properties upon regular perturbations

2022

In this survey, we present some results on the behavior of effective properties in presence of perturbations of the geometric and physical parameters. We first consider the case of a Newtonian fluid flowing at low Reynolds numbers around a periodic array of cylinders. We show the results of [43], where it is proven that the average longitudinal flow depends real analytically upon perturbations of the periodicity structure and the cross section of the cylinders. Next, we turn to the effective conductivity of a periodic two-phase composite with ideal contact at the interface. The composite is obtained by introducing a periodic set of inclusions into an infinite homogeneous matrix made of a di…

perturbed domainintegral equationsSettore MAT/05 - Analisi Matematicatransmission problemEffective conductivity; Integral equations; Longitudinal flow; Periodic composite; Perturbed domain; Transmission problemperiodic compositeeffective conductivityLongitudinal flow
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Isolation of Four Lytic Phages Infecting Klebsiella pneumoniae K22 Clinical Isolates from Spain

2020

This article belongs to the Special Issue Bacteriophage—Molecular Studies.

phage therapyPhage therapyPhage therapyKlebsiella pneumoniae<i>Klebsiella pneumoniae</i>medicine.medical_treatmentGenome ViralArticleHost SpecificityCatalysisMicrobiologylcsh:ChemistryInorganic ChemistryBacteriophageViral Proteins03 medical and health sciencesPodoviridaeProtein DomainsbacteriophagemedicineHumansBacteriophagesTypingPhysical and Theoretical ChemistryBacteriophagelcsh:QH301-705.5Molecular BiologyPhylogenySpectroscopy030304 developmental biologyWhole genome sequencingInfectivityLikelihood Functions0303 health sciencesbiology030306 microbiologyOrganic ChemistryGeneral Medicinebiology.organism_classification3. Good healthComputer Science ApplicationsKlebsiella pneumoniaelcsh:Biology (General)lcsh:QD1-999Lytic cycleSpainInternational Journal of Molecular Sciences
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Platformed Interactions: How Social Media Platforms Relate to Candidate–Constituent Interaction During Finnish 2015 Election Campaigning

2020

Interaction between candidates and constituents via social media is a well-studied domain. The article takes this research further through a synthesis with platform studies, emerging scholarship that applies a critical perspective to the role of digital platforms in society. Examination of candidate–constituent interaction via Twitter and Facebook during the 2015 Finnish parliamentary elections revealed that the types of interaction differ between the two platforms: Facebook was used for formal campaigning and for praising and expressing support, while Twitter was utilized for information and for seeking and sharing opinions. An additional finding is that interaction approaches may be plat…

poliitikotCultural Studiessocial mediapoliittinen viestintä518 Media and communicationssosiaalinen media050801 communication & media studiessosiaalinen vuorovaikutuslcsh:Communication. Mass mediaDomain (software engineering)0508 media and communications050602 political science & public administrationSocial mediaSociologyviestintäCommunication05 social sciencesMedia studieselectoral campaigningsocial interaction16. Peace & justicelcsh:P87-96Social relation0506 political scienceComputer Science ApplicationsScholarshipvaalikampanjatpoliticianscommunicative functionsSocial Media + Society
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Petro-archaeology of Gallo-Roman lime mortar. Attempt to reconstruction and interpretation of the “chaînes opératoires”: from material to ancient cra…

2003

Petro-archaeological research on Gallo-Roman lime mortars is based on a simple analytical methodology: observations with optical microscopy in transmission, which brings us a maximum of data about the material and the various stages of the “chaîne opératoire”. This work enabled us to draw the general features of the craftmanship (common practices of the ancient structores and tectores), to establish the relations between mortar composition and its “primary” and “secondary” architectural function, then to perceive what are the markers and motivations of the formula adaptations. The importance of the geological environment is shown, because it induces economic and technical choices, requiring…

pozzolanic reactions[ SHS.HIST ] Humanities and Social Sciences/Historychantier de constructionchauxpeinture muralemortierbuilding siteréactions pouzzolaniques[ OTHER ] domain_other[OTHER]domain_otherArchaeologyArchéologie[SHS.HIST] Humanities and Social Sciences/History[OTHER] domain_othermortargallo-romainlime[SHS.HIST]Humanities and Social Sciences/Historywall painting
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Lenses on very curved zones of a singular line field of ${\mathbb C}^2$ or of a singular plane field of ${\mathbb C}^3$

2020

We renormalize, using suitable lenses, small domains of a singular holomorphic line field of ${\mathbb C}^2$ or plane field of ${\mathbb C}^3$ where the curvature of a plane-field is concentrated. At a proper scale the field is almost invariant by translations. When the field is integrable, the leaves are locally almost translates of a surface that we will call {\it profile}. When the singular rays of the tangent cone (a generalization to a plane-field of the tangent cone of a singular surface is defined) are isolated, we obtain more precise results. We also generalize a result of Merle (\cite{Me}) concerning the contact order of generic polar curves with the singular level $f=0$ when $\ome…

profile[mathIT][MATH.MATH-AG] Mathematics [math]/Algebraic Geometry [math.AG]profile domains [mathAG][MATH] Mathematics [math]complex polynomialisolated singularity[mathGT][MATH.MATH-DG]Mathematics [math]/Differential Geometry [math.DG]complex one-form[MATH.MATH-AG]Mathematics [math]/Algebraic Geometry [math.AG][MATH]Mathematics [math][MATH.MATH-DG] Mathematics [math]/Differential Geometry [math.DG]polar curve[mathDG]
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Elaboración de la prueba de orientación y medición académica (POMA) previa al ingreso a los estudios superiores en la República Dominicana

2004

espanolAnte el imperativo legal de desarrollar una "prueba inicial de medicion y orientacion previa al ingreso a los Estudios Superiores" (Ley 139-0 l ), el autor propone a la SEESCYT, dadas las condiciones educativas de la Republica .Dominicana, evaluar el constructo Inteligencia Academica. Para probar lo adecuacion de este tipo de evaluacion el autor construye un instrumento de medida, el IAUD que es aplicado a un muestra de 402 alumnos de primer ano de ingreso a las u niversidades dominicanas. Este trabajo viene a ser la presentacion de las fases metodologicas utilizadas en el proceso de construccion de esla prueba , tales como: la definicion del atributo, el desarrollo del modelo de pro…

psicometríaDomain (biology)pruebas de aptitudPOMA.Pharmacology (medical)lcsh:H1-99Sociologypruebas psicológicaslcsh:Social sciences (General)Humanitieslcsh:P87-96lcsh:Communication. Mass mediaCiencia y Sociedad
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Brevi note a margine di Cassazione 23 marzo 2017 n. 7551 in tema di sdemanializzazione tacita

2017

La sentenza della Cassazione 23 marzo 2017 n. 7551 ribadisce il principio che la natura demaniale marittima di un terreno non può essere esclusa se non in forza di un provvedimento amministrativo. Non può pertanto il giudice sostituirsi all’amministrazione in tale valutazione discrezionale. The judgment of the Supreme Court (n° 7551/2017) reiterates the principle according to which the public maritime nature of an area can not be excluded except by virtue of an administrative decision. Therefore, the judge can not substitute the administration for this discretionary assessment.

public maritime domainSettore IUS/06 - Diritto Della Navigazionedemanio marittimosdemanializzazione
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