Search results for "DPM."
showing 8 items of 8 documents
Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling
2021
The tuberal hypothalamic ventral premamillary nucleus (VPM) described in mammals links olfactory and metabolic cues with mating behavior and is involved in the onset of puberty. We offer here descriptive and experimental evidence on a migratory phase in the development of this structure in mice at E12.5–E13.5. Its cells originate at the retromamillary area (RM) and then migrate tangentially rostralward, eschewing the mamillary body, and crossing the molecularly distinct perimamillary band, until they reach a definitive relatively superficial ventral tuberal location. Corroborating recent transcriptomic studies reporting a variety of adult glutamatergic cell types in the VPM, and different p…
Systemic acidemia impairs cardiac function in critically Ill patients.
2021
Background: Acidemia, is associated with reduced cardiac function in animals, but no studies showing an effect of acidemia on cardiac function in humans are reported. In the present study, we examined the effect of acidemia on cardiac function assessed with transpulmonary thermodilution technique with integrated pulse contour analysis (Pulse Contour Cardiac Output, PiCCO™) in a large cohort of critically ill patients. Methods: This was a prospective multicenter observational cross-sectional study of 297 patients from 6 intensive care units in London, England selected from all patients admitted consecutively between May 2018 and March 2019. Measurements of lowest plasma pH and concurrent ass…
Overcoming traditional Performance Management in Public Healthcare Institutions: The need for a DPM Approach
Donabedian (1988) was the scientific father of the notion that Performance Measurement (PM) of hospital outputs leads to improved quality of healthcare services, setting the foundations of how hospital quality is still today defined, considered and measured using three different kinds of measures: structure, process and outcome measures. Nonetheless, a growing part of literature during the last two decades has started doubting those favourable outcomes of PM on hospital quality (De Vos, et al., 2009; Nolan & Berwick, 2006; Werner et al., 2008a, 2008b; Werner & Bradlow, 2006; Wright & Hershman, 2014) while other research shows that ineffective PM systems are not just useless but …
A dynamic performance management approach to frame corruption in public procurement: a case study
2021
Purpose The purpose of this paper is to frame the causal relationships between corruption in public procurement and performance of local governments. Design/methodology/approach An outcome-based dynamic performance management approach is adopted to explore a representative case study of a small Italian municipality. The model is based on three sources: qualitative primary data generated by face-to-face convergent interviews; secondary data retrieved from documents describing legal cases linked to procurement and open-access repositories; and an extensive literature review. Findings Emphasizing the role of community civic morality systemically may help to understand some counterintuitive re…
DYNAMIC PERFORMANCE MANAGEMENT IN THE UPSTREAM OIL INDUSTRY
This is a study about investments in the upstream oil industry. The goal is to describe how investments that lead to oil and gas production, are made. The study of oil supply is central, because it represents 60% of the world’s primary energy supply. It is vital for energy renewables policy makers, in order to assess oil supply scenarios and adjust incentives for lower fossils consumption. It is also important for consuming countries. Previous studies have stressed the importance of market volatility for investment appraisal in the UK; irreversibility of investments; and remaining reserves as main drivers of investment and production in the UK. My study differs, since my results can be comp…
Governing Local Area Development through Dynamic Performance Management
2017
Several attempts of local areas development fail due to a predominant attention to the internal performance of public organizations. The perspective of local area development may enhance performance management in public entities by considering: a) their outcomes in the local area; b) the inter-institutional relationships actable with other local areas’ organizations to achieve such outcome; c) the improvement of the activity of other social institutions, enterprises and families, through networking and trust. This paper proposes a dynamic performance management (DPM) conceptual model to govern local area development and includes a case study of the Integrated Water System of Agrigento, Ital…
Why do Traditional Performance Management Systems in Healthcare not always lead to Improved Performance? Outlining the Unintended Consequences of the…
2021
Researchers all around the globe have not yet come to an end as regards the supposed positive impact of traditional performance management systems in healthcare, and some research has shown that, paradoxically, performance management policies do not always lead to improved hospital performance. Despite the extensive research identifying the “pitfalls” of the NPM reforms around Europe and the unintended consequences for hospital staff and patients, little is known about the mechanisms that caused those negative effects, which essentially creates a research gap worth investigating. This PhD study tries to address this gap and show why do traditional PM Systems in healthcare not always lead to…