Search results for "Data Science"

Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.

2012

AbstractOmic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of omic techniques is crucial for understanding and interpretation of TCM development, especially in view of its expansion in Western countries. In this short review, omic applications in TCM research are reviewed which has allowed some speculation regarding future perspectives for these approaches in TCM modernisation and standardisation. Guidelines for good practice for …

Comparison of classification methods that combine clinical data and high-dimensional mass spectrometry data

2013

Background The identification of new diagnostic or prognostic biomarkers is one of the main aims of clinical cancer research. Technologies like mass spectrometry are commonly being used in proteomic research. Mass spectrometry signals show the proteomic profiles of the individuals under study at a given time. These profiles correspond to the recording of a large number of proteins, much larger than the number of individuals. These variables come in addition to or to complete classical clinical variables. The objective of this study is to evaluate and compare the predictive ability of new and existing models combining mass spectrometry data and classical clinical variables. This study was co…

The use of research assistants in polydiagnostic research.

1988

La bioinformática en la práctica médica: Integración de datos biológicos y clínicos

2008

The aim of our work is to describe essential aspects of Medical Informatics, Bioinformatics and Biomedical Informatics, that are used in biomedical research and clinical practice. These disciplines have emerged from the need to find new scientific and technical approaches to manage, store, analyze and report data generated in clinical practice and molecular biology and other medical specialties. It can be also useful to integrate research information generated in different areas of health care. Moreover, these disciplines are interdisciplinary and integrative, two key features not shared by other areas of medical knowledge. Finally, when Bioinformatics and Biomedical Informatics approach to…

[Impact factor: what having one means to a scientific journal].

2005

Formations of Monoids, Congruences, and Formal Languages

2015

The main goal in this paper is to use a dual equivalence in automata theory started in [25] and developed in [3] to prove a general version of the Eilenberg-type theorem presented in [4]. Our principal results confirm the existence of a bijective correspondence between three concepts; formations of monoids, formations of languages and formations of congruences. The result does not require finiteness on monoids, nor regularity on languages nor finite index conditions on congruences. We relate our work to other results in the field and we include applications to non-r-disjunctive languages, Reiterman s equational description of pseudovarieties and varieties of monoids.

Statistical guidelines for quality control of next-generation sequencing techniques.

2021

Condition-specific statistical guidelines and accurate classification trees for quality control of functional genomics NGS files (RNA-seq, ChIP-seq and DNase-seq) have been generated using thousands of reference files from the ENCODE project and made available to the community.

An AMI System for User Daily Routine Recognition and Prediction

2014

Ambient Intelligence (AmI) defines a scenario involving people living in a smart environment enriched by pervasive sensory devices with the goal of assisting them in a proactive way to satisfy their needs. In a home scenario, an AmI system controls the environment according to a user’s lifestyle and daily routine. To achieve this goal, one fundamental task is to recognize the user’s activities in order to generate his daily activities profile. In this chapter, we present a simple AMI system for a home scenario to recognize and predict users’ activities. With this predictive capability, it is possible to anticipate their actions and improve their quality of life. Our approach uses a Hidden M…

Mechanism change in a simulation of peer review: from junk support to elitism

2014

Abstract Peer review works as the hinge of the scientific process, mediating between research and the awareness/acceptance of its results. While it might seem obvious that science would regulate itself scientifically, the consensus on peer review is eroding; a deeper understanding of its workings and potential alternatives is sorely needed. Employing a theoretical approach supported by agent-based simulation, we examined computational models of peer review, performing what we propose to call redesign, that is, the replication of simulations using different mechanisms. Here, we show that we are able to obtain the high sensitivity to rational cheating that is present in literature. In additio…

Mapping recent information behavior research: an analysis of co-authorship and cocitation networks

2015

There has been an increase in research published on information behavior in recent years, and this has been accompanied by an increase in its diversity and interaction with other fields, particularly information retrieval (HR). The aims of this study are to determine which researchers have contributed to producing the current body of knowledge on this subject, and to describe its intellectual basis. A bibliometric and network analysis was applied to authorship and co-authorship as well as citation and co-citation. According to these analyses, there is a small number of authors who can be considered to be the most productive and who publish regularly, and a large number of transient ones. Ot…