Search results for "Density"

showing 10 items of 4402 documents

Incidence of bisphosphonate-associated osteonecrosis of the jaws in breast cancer patients.

2009

BACKGROUND: Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is a relatively new disease. The aim of this study was to evaluate the prevalence of BP-ONJ in breast cancer patients with osseous metastasis and bisphosphonate therapy. METHODS: A retrospective study was conducted in a EUSOMA accredited breast unit in Germany. All patients treated from January of 2000 to March of 2006 with metastatic breast cancer and bisphosphonate therapy were reviewed. All patients were contacted, and missing data were completed through structured interviews with their dentists and physicians (n = 75). Primary outcome was the development of BP-ONJ and the detection of possible additional trigger fa…

AdultCancer Researchmedicine.medical_specialtymedicine.medical_treatmentOral Surgical ProceduresBone NeoplasmsBreast NeoplasmsBreast cancerInternal medicineMedicineHumansAgedRetrospective StudiesAged 80 and overBone Density Conservation AgentsDiphosphonatesbusiness.industryIncidence (epidemiology)IncidenceOsteonecrosisBone metastasisCancerRetrospective cohort studyBisphosphonateMiddle Agedmedicine.diseasePrognosisMetastatic breast cancerSurgeryOncologyBreast diseasebusinessJaw DiseasesCancer
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Differences between tight and loose cultures: a 33-nation study.

2011

With data from 33 nations, we illustrate the differences between cultures that are tight (have many strong norms and a low tolerance of deviant behavior) versus loose (have weak social norms and a high tolerance of deviant behavior). Tightness-looseness is part of a complex, loosely integrated multilevel system that comprises distal ecological and historical threats (e.g., high population density, resource scarcity, a history of territorial conflict, and disease and environmental threats), broad versus narrow socialization in societal institutions (e.g., autocracy, media regulations), the strength of everyday recurring situations, and micro-level psychological affordances (e.g., prevention …

AdultCross-Cultural ComparisonMalePermissivenessSocial Valuesmedia_common.quotation_subject050109 social psychologySocial value orientationsAutocracyConformityYoung AdultSocial ConformityCultural diversity0502 economics and businessCultural diversityHumans0501 psychology and cognitive sciencesSocial Behaviormedia_commonPopulation DensityBehaviorMultidisciplinaryScience & TechnologyCultural CharacteristicsPolitical Systems05 social sciences1. No povertyCross-cultural studiesSELFSocial Control FormalSocial normsPolitical economyGovernmentCultural rightsFemale050203 business & managementDeviance (sociology)Social controlTightness-loosenessScience (New York, N.Y.)
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Effect of undersized drilling on the stability of immediate tapered implants in the anterior maxillary sector. A randomized clinical trial.

2020

Background To evaluate the effect of undersized drilling on the primary and secondary stability of immediate implants placed in the anterior maxilla. Material and Methods A comparative randomized clinical trial was carried out in 30 healthy adults. Thirty tapered implants, 16 involving conventional drilling and 14 undersized drilling, were placed immediately after anterior maxillary tooth removal. Insertion torque and implant stability assessed by resonance frequency analysis (RFA) were evaluated at three different timepoints: at implant placement and 6 and 12 weeks post-implantation. The results were compared using parametric statistical tests. Results All implants showed adequate stabilit…

AdultDentistryOsseointegrationMaxillary toothlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawBone DensityOsseointegrationosteoradionecrosisMaxillaMedicineHumansradiotherapy bone necrosisGeneral DentistryUNESCO:CIENCIAS MÉDICASteriparatideDental Implantsbusiness.industryResearchDental Implantation EndosseousResonance Frequency AnalysisDrilling030206 dentistrylow level laser therapyImplant placementResonance frequency analysispentoxifyllineOtorhinolaryngologyTorquehyperbaric oxygenMaxillaSurgeryImplantbusinessImplantologyMedicina oral, patologia oral y cirugia bucal
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Long-term leisure time physical activity and properties of bone: A twin study

2009

Effects of physical activity on bone properties, when controlled for genetic effects, are not fully understood. We aimed to study the association between long-term leisure time physical activity (LTPA) and bone properties using twin pairs known to be discordant for leisure time physical activity for at least 30 yr. Volumetric BMD and geometric properties were measured at the tibia shaft and distal end using pQCT in 16 middle-aged (50-74 yr) same-sex twin pairs (seven monozygotic [MZ] and nine dizygotic [DZ] pairs) selected from a population-based cohort. Paired differences between active and inactive co-twins were studied. Active members of MZ twin pairs had larger cortical bone cross-secti…

AdultGerontologymedicine.medical_specialtyHistologyAdolescentBone densityPhysiologyEndocrinology Diabetes and MetabolismOsteoporosisPopulationLong boneLeisure timePhysical activityPhysical exercise030209 endocrinology & metabolismMotor ActivityCohort StudiesYoung Adult03 medical and health sciences0302 clinical medicineBone DensityInternal medicinemedicineHumansOrthopedics and Sports MedicineTibia030212 general & internal medicineeducationAged030304 developmental biology0303 health scienceseducation.field_of_studyTibiabusiness.industryMiddle Agedmedicine.diseaseTwin studyTerm (time)SurgeryCross-Sectional StudiesEndocrinologymedicine.anatomical_structureCortical boneTomography X-Ray ComputedbusinessBone
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Effects of an ultra-long-distance (1000 km) race on lipid metabolism

1989

The influence was examined of ultra-long-distance running (1000 km race lasting 20 days) on changes in serum lipids. The 110 participants received two types of diet, a conventional Western diet and a wholesome vegetarian diet. Of the 55 finishers the serum concentration of total cholesterol, low density lipoprotein (LDL)-cholesterol, apolipoprotein B and triglycerides decreased significantly during the first 8 days of the run, but rose again towards the end of the race without reaching pre-race levels. The high density lipoprotein (HDL)-cholesterol increased initially but decreased in the final days of the run. The values for apolipoprotein A-I were not correlated with HDL-cholesterol. The …

AdultGlycerolMalemedicine.medical_specialtyApolipoprotein BPhysiologyBlood lipidsFatty Acids NonesterifiedRunningchemistry.chemical_compoundHigh-density lipoproteinPhysiology (medical)Internal medicinemedicineHumansOrthopedics and Sports MedicineApolipoproteins ATriglyceridesAgedApolipoproteins BbiologyTriglycerideCholesterolCholesterol HDLPublic Health Environmental and Occupational HealthLipid metabolismGeneral MedicineMiddle AgedLipid MetabolismDietCholesterolEndocrinologychemistryLow-density lipoproteinbiology.proteinFemalelipids (amino acids peptides and proteins)LipoproteinEuropean Journal of Applied Physiology and Occupational Physiology
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Loading modalities and bone structures at nonweight-bearing upper extremity and weight-bearing lower extremity: a pQCT study of adult female athletes.

2005

This cross-sectional study of adult female athletes assessed whether the apparent loading-related differences in bone structure are primarily associated with the loading type or the muscle performance-related joint moments. Several structural variables at shaft sites of the tibia, radius and humerus, and distal sites of the tibia and radius were measured with peripheral quantitative computed tomography (pQCT) among 113 female national level athletes (representing hurdling, volleyball, soccer, racket-sports and swimming) and their 30 nonathletic referents. For the weight-bearing lower extremities, the loading modalities of the above sports were classified into high-impact (hurdling, volleyba…

AdultHistologyTime FactorsAdolescentPhysiologyEndocrinology Diabetes and MetabolismOsteoporosismedicine.disease_causeBone and BonesWeight-bearingUpper ExtremityWeight-BearingAbsorptiometry PhotonBone DensitymedicineHumansHumerusTibiaQuantitative computed tomographyAnalysis of Variancemedicine.diagnostic_testbiologyTibiaAthletesbusiness.industryAnatomymedicine.diseasebiology.organism_classificationDiaphysisRadiusmedicine.anatomical_structureLower ExtremityUpper limbFemalebusinessSportsBone
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Enzymatic modification of low-density lipoprotein in the arterial wall: a new role for plasmin and matrix metalloproteinases in atherogenesis.

2004

Objective— Functionally interactive proteases of the plasminogen/plasmin and the matrix metalloproteinase (MMP) system degrade and reorganize the extracellular matrix of the vessel wall in atherosclerosis. Here we investigated whether such proteases are able to confer atherogenic properties onto low density lipoprotein by nonoxidative modification. Methods and Results— Similar to the recently described enzymatically-modified low-density lipoprotein (E-LDL), native LDL exposed to plasmin or matrix MMP-2 or MMP-9 and cholesterylester-hydrolase (CEH) showed extensive deesterification, with ratios of free cholesterol to total cholesterol rising to 0.8 compared with 0.2 in native LDL. When the …

AdultLipoprotein modificationProteasesAdolescentPlasminArteriosclerosisBlotting WesternMatrix metalloproteinaseComplement Hemolytic Activity AssayMonocyteschemistry.chemical_compoundmedicineHumansTrypsinFibrinolysinComplement ActivationCells CulturedAgedbiologyMacrophagesAntibodies MonoclonalSodium Dodecyl SulfateLipoprotein(a)Middle AgedSterol EsteraseCell biologyLipoproteins LDLC-Reactive ProteinchemistryBiochemistryMatrix Metalloproteinase 9Low-density lipoproteinbiology.proteinMatrix Metalloproteinase 2lipids (amino acids peptides and proteins)Electrophoresis Polyacrylamide GelCardiology and Cardiovascular MedicinePlasminogen activatormedicine.drugLipoproteinArteriosclerosis, thrombosis, and vascular biology
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Association between long-term exercise loading and lumbar spine trabecular bone score (TBS) in different exercise loading groups

2015

Objective: To examine whether different exercise loading is associated with lumbar vertebral texture as assessed with Trabecular Bone Score (TBS). Methods: Data from 88 Finnish female athletes and 19 habitually active women (reference group) were analyzed. Participants’mean age was 24.3 years(range 17-40 years).Athletes were divided into five specific exercise loading groups according to sport-specific training history: high-impact (triple jumpers and high jumpers), odd-impact (soccer players and squash players), high-magnitude (power lifters), repetitive impact (endurance runners), and repetitive non-impact (swimmers). TBS-values were determined from lumbar vertebral L1-L4 DXA images. Body…

AdultLumbar VertebraeTime FactorsAdolescentosteoporoosiluuntiheysBone architectureYoung AdultAbsorptiometry PhotonAthletesBone DensityOsteoporosisHumansOriginal ArticleFemalehuman activitiesExerciseurheilijatJournal of Musculoskeletal & Neuronal Interactions
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Focal airtrapping at expiratory high-resolution CT: comparison with pulmonary function tests

2000

This study was undertaken to determine prevalence, extent, and severity of focal airtrapping at expiratory high-resolution CT, and to compare focal airtrapping with age, gender, pulmonary function tests, and blood gas analysis. Two-hundred seventeen patients with and without pulmonary disease underwent paired inspiratory/expiratory high-resolution CT. Six scan pairs with corresponding scan levels were visually assessed for focal – not diffuse – airtrapping using a four-point scale. Pulmonary function tests and blood gas analysis were available for correlation in all patients (mean interval 5 days). Focal airtrapping with lower lung predominance was observed in 80 % of patients. Twenty-six o…

AdultLung DiseasesMalemedicine.medical_specialtyAdolescentHigh resolutionSeverity of Illness IndexPulmonary function testingHumansMedicineRadiology Nuclear Medicine and imagingLung volumesProspective StudiesAgedNeuroradiologyAged 80 and overLungbusiness.industryRespirationUltrasoundGeneral MedicineNormal lung functionMiddle AgedRespiratory Function TestsLung densitymedicine.anatomical_structureFemaleRadiologyBlood Gas AnalysisArtifactsTomography X-Ray ComputedbusinessEuropean Radiology
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A semi-automatic approach for epicardial adipose tissue segmentation and quantification on cardiac CT scans

2019

Abstract Many studies have shown that epicardial fat is associated with a higher risk of heart diseases. Accurate epicardial adipose tissue quantification is still an open research issue. Considering that manual approaches are generally user-dependent and time-consuming, computer-assisted tools can considerably improve the result repeatability as well as reduce the time required for performing an accurate segmentation. Unfortunately, fully automatic strategies might not always identify the Region of Interest (ROI) correctly. Moreover, they could require user interaction for handling unexpected events. This paper proposes a semi-automatic method for Epicardial Fat Volume (EFV) segmentation a…

AdultMale0301 basic medicineComputer scienceAdipose tissueHealth InformaticsCalcium score scans; Cardiac adipose tissue quantification; Coronary computed tomography angiography scans; Epicardial fat volume; Fat density quartiles; Semi-automatic segmentationFat density quartilesCorrelation03 medical and health sciencesComputer-AssistedDeep Learning0302 clinical medicineFat density quartileRegion of interestImage Interpretation Computer-AssistedCalcium score scansHumansSegmentationCalcium score scans; Cardiac adipose tissue quantification; Coronary computed tomography angiography scans; Epicardial fat volume; Fat density quartiles; Semi-automatic segmentation; Adipose Tissue; Adult; Algorithms; Deep Learning; Female; Humans; Image Interpretation Computer-Assisted; Male; Middle Aged; Pericardium; Tomography X-Ray ComputedImage InterpretationTomographyEpicardial fat volumeSemi-automatic segmentationbusiness.industryCalcium score scanPattern recognitionRepeatabilityMiddle AgedCoronary computed tomography angiography scansCoronary computed tomography angiography scanX-Ray ComputedComputer Science Applications030104 developmental biologyAdipose TissueCardiac adipose tissue quantificationQuartileEpicardial adipose tissueFemaleSemi automaticArtificial intelligenceTomography X-Ray ComputedSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessPericardiumAlgorithms030217 neurology & neurosurgeryComputers in Biology and Medicine
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