Search results for "Derivative"

showing 10 items of 1074 documents

Oligomere aus gleichsinnig angeordneten Chalkon-Bausteinen

1999

The cross-conjugated oligomers 1a–d, which contain up to eight alternately arranged chalcone building blocks, were prepared by stereoselective condensation reactions of formyl and acetyl components. The synthetic sequence started with 1,4-dibromo-2,5-dipropoxybenzene (2). Bouveault reactions with DMF and DMA yielded the aldehydes 3 and 6 and the ketones 7 and 10. After the protection of the carbonyl group (3 4 and 7 8), a further Bouveault reaction led to monoprotected dialdehyd 5 and diketone 9, respectively. Repetitive condensation reactions starting with the acetophenone derivative 11 and 5 furnished the aldehyde 12, the ketone 13 and the aldehyde 14. In the final step the target compoun…

Diketonechemistry.chemical_classificationChalconechemistry.chemical_compoundKetonechemistryStereochemistryStereoselectivityCondensation reactionMedicinal chemistryAldehydeDerivative (chemistry)AcetophenoneJournal für praktische Chemie
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Enzymatic esterification of bicyclic meso-diols derived from 1,4-bis(hydroxymethyl)furan. An enantioselective Diels–Alder reaction equivalent

1998

Abstract meso -Diols derived from the Diels–Alder adduct 1,4-bis(hydroxymethyl)furan/dimethyl acetylenedicarboxylate can be enantioselectively monoacetylated under CRL or PSL catalysis with very good yields and moderate to excellent ees. (+)-Monoacetates are always preferentially formed in the reactions catalyzed by CRL, and their (−)-enantiomers are the main products in the acetylations under PSL catalysis. Absolute configurations have been determined by X-ray analysis of a single crystal of an ( R )-α-methoxyphenylacetyl derivative.

Dimethyl acetylenedicarboxylateBicyclic moleculeChemistryOrganic ChemistryEnantioselective synthesisMedicinal chemistryCatalysisAdductInorganic Chemistrychemistry.chemical_compoundFuranHydroxymethylPhysical and Theoretical ChemistryDerivative (chemistry)Diels–Alder reactionTetrahedron: Asymmetry
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ChemInform Abstract: Synthesis and Chemical Reactivity of 5-Methoxy-2-vinyl-4-azaindoles.

2010

Abstract 2-Vinyl-4-azaindoles are less reactive with dienophiles than 2-vinylindoles. 5-Methoxy-2-vinyl-4-azaindole 2a and its 1-methyl derivative 2a reacts with N-phenylmaleimide to yield cycloadducts only under vigorous conditions. 2b produces a cycloadduct with dimethyl acetylenedicarboxylate, while 2a yields a Michael-type adduct. Reactions with more reactive dienophiles gave only polymeric products.

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundAddition reactionchemistryYield (chemistry)technology industry and agricultureGeneral MedicineMedicinal chemistryDerivative (chemistry)AdductChemInform
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ChemInform Abstract: Reaction of 2,2′-Bis(N-methylindolyl) with Dimethyl Acetylenedicarboxylate and Thermally and Photochemically Induced Cyclization…

2010

2,2′-Bis(N-methylindolyl) 1 reacts with dimethyl acetylenedicarboxylate to furnish the 3-dimethyl maleoyl-substituted 2,2′-bisindolyl 2. Compound 2 cyclizes under aluminum trichloride catalysis according to a polar process to give a cyclopenta[2,1-b:3,4-b′]diindole derivative 4. Reaction of compound 4 with benzyl-amine yields the spiro derivative 5. Photochemically-induced 1,6-electrocyclization of compound 2 gives rise to the indolo[2,3-a]carbazole 6 directly, which is readily transformed to the pyrrolo-annelated carbazole 7 by treatment with benzylamine.

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundBenzylaminechemistryCarbazoleAluminum trichlorideGeneral MedicineMedicinal chemistryDerivative (chemistry)CatalysisChemInform
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Reaction of 2,2′-bis(N-methylindolyl) with dimethyl acetylenedicarboxylate and thermally- and photochemically-induced cyclizations of the product

1995

2,2′-Bis(N-methylindolyl) 1 reacts with dimethyl acetylenedicarboxylate to furnish the 3-dimethyl maleoyl-substituted 2,2′-bisindolyl 2. Compound 2 cyclizes under aluminum trichloride catalysis according to a polar process to give a cyclopenta[2,1-b:3,4-b′]diindole derivative 4. Reaction of compound 4 with benzyl-amine yields the spiro derivative 5. Photochemically-induced 1,6-electrocyclization of compound 2 gives rise to the indolo[2,3-a]carbazole 6 directly, which is readily transformed to the pyrrolo-annelated carbazole 7 by treatment with benzylamine.

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundBenzylaminechemistryCarbazoleAluminum trichlorideOrganic ChemistryOrganic chemistryMedicinal chemistryDerivative (chemistry)CatalysisJournal of Heterocyclic Chemistry
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Synthesis and Chemical Reactivity of 5-Methoxy-2-vinyl-4-azaindoles

1997

Abstract 2-Vinyl-4-azaindoles are less reactive with dienophiles than 2-vinylindoles. 5-Methoxy-2-vinyl-4-azaindole 2a and its 1-methyl derivative 2a reacts with N-phenylmaleimide to yield cycloadducts only under vigorous conditions. 2b produces a cycloadduct with dimethyl acetylenedicarboxylate, while 2a yields a Michael-type adduct. Reactions with more reactive dienophiles gave only polymeric products.

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundchemistryYield (chemistry)Organic Chemistrytechnology industry and agricultureOrganic chemistryDerivative (chemistry)AdductSynthetic Communications
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Shape optimization for monge-ampére equations via domain derivative

2011

In this note we prove that, if $\Omega$ is a smooth, strictly convex, open set in $R^n$ $(n \ge 2)$ with given measure, the $L^1$ norm of the convex solution to the Dirichlet problem $\det D^2 u=1$ in $\Omega$, $u=0$ on $\partial\Omega$, is minimum whenever $\Omega$ is an ellipsoid.

Dirichlet problemMathematical optimizationPure mathematicsFictitious domain methodDomain derivativeApplied MathematicsOpen setRegular polygonMonge–Ampère equationMonge-Ampère equationSettore MAT/05 - Analisi MatematicaGeneralizations of the derivativeNorm (mathematics)Discrete Mathematics and CombinatoricsAffine isoperimetric inequalitiesConvex functionAnalysisMathematics
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Metric regularity and subdifferential calculus in Banach spaces

1995

In this paper we give verifiable conditions in terms of limiting Frechet subdifferentials ensuring the metric regularity of a multivalued functionF(x)=−g(x)+D. We apply our results to the study of the limiting Frechet subdifferential of a composite function defined on a Banach space.

Discrete mathematicsComposite functionPure mathematicsApplied MathematicsBanach spaceLimitingSubderivativemedicine.diseaseMetric (mathematics)medicineVerifiable secret sharingAnalysisCalculus (medicine)MathematicsSet-Valued Analysis
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Weak regularity of functions and sets in Asplund spaces

2006

Abstract In this paper, we study a new concept of weak regularity of functions and sets in Asplund spaces. We show that this notion includes prox-regular functions, functions whose subdifferential is weakly submonotone and amenable functions in infinite dimension. We establish also that weak regularity is equivalent to Mordukhovich regularity in finite dimension. Finally, we give characterizations of the weak regularity of epi-Lipschitzian sets in terms of their local representations.

Discrete mathematicsDimension (vector space)Applied MathematicsPartition regularityMathematics::Optimization and ControlSubderivativeAnalysisMathematicsNonlinear Analysis: Theory, Methods & Applications
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BLD -mappings in $W^{2,2}$ are locally invertible

2000

We prove that mappings of bounded length distortion are local homeomorphisms if they have L 2 -integrable weak second derivatives.

Discrete mathematicsDistortion (mathematics)Invertible matrixIntegrable systemlawGeneral MathematicsBounded functionMathematics::General TopologySecond derivativeMathematicslaw.inventionMathematische Annalen
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