Search results for "Different"

Low levels of both xanthine dehydrogenase and of cellular retinol binding protein are responsible for retinoic acid deficiency in malignant human mam…

2009

The seeming impairment of retinoid metabolism in human breast tumor cells has been attributed to the lower expression of cellular retinol binding proteins (CRBPs), of alcohol/retinol dehydrogenases, or aldehyde/retinaldehyde dehydrogenases. In a previous study we indicated that xanthine dehydrogenase (XDH) is able to oxidize actively both all-trans-retinol (t-ROL) bound to the CRBP (holo-CRBP) and all-trans-retinaldehyde (t-RAL) to all-trans-retinoic acid (t-RA) in human mammary epithelial cells (HMEC). Since both XDH and CRBP are required for the biosynthesis of t-RA, we have inspected their bioavailability in both estrogen-responsive and nonresponsive human mammary epithelial cancer cells…

Retrotranspozonu struktūra parastās priedes (Pinus sylvestris L.) genomā un to ekspresija

2014

ANOTĀCIJA Promocijas darbs izstrādāts Latvijas Valsts mežzinātnes institūtā „Silava”. Pētījuma mērķis bija identificēt aktīvos retrotranspozonus parastās priedes (Pinus sylvestris L.) genomā un raksturot to transkripcijas līmeni dažādu stresa veidu ietekmē kontrolētos apstākļos. Pētījumā izmantoti nespecifiskie retrotranspozonu marķieri balstīti uz augsti konservatīvām tRNS piesaistes vietām. Viena klona priežu rametus pakļāva dabā izplatītam karstuma stresam, kukaiņu invāzijai (priežu hermess (Pineus pini L.), kā arī mākslīgi izraisītai augu hormonu (abscīzskābes un salicilskābes) ietekmei. Darba rezultātā identificēti pārsvarā I klases mobīlo elementu pārstāvji, kā arī tos saturošie himēr…

Photoluminescent Detection of Human T-Lymphoblastic Cells by ZnO Nanorods.

2020

The precise detection of cancer cells currently remains a global challenge. One-dimensional (1D) semiconductor nanostructures (e.g., ZnO nanorods) have attracted attention due to their potential use in cancer biosensors. In the current study, it was demonstrated that the possibility of a photoluminescent detection of human leukemic T-cells by using a zinc oxide nanorods (ZnO NRs) platform. Monoclonal antibodies (MABs) anti-CD5 against a cluster of differentiation (CD) proteins on the pathologic cell surface have been used as a bioselective layer on the ZnO surface. The optimal concentration of the protein anti-CD5 to form an effective bioselective layer on the ZnO NRs surface was selected. …

Size Matters… And Age Too - Differentiated Integration Approach to the Functions of the EU Council Rotating Presidency

2022

The objective of this paper is to present how the roles attributed to the institution of the EU Council Rotating Presidency changed after the reform of the Lisbon Treaty. It argues that the legal modifications introduced by the treaty brought about some further going changes of the roles performed by the EU member state presiding the EU Council. The analysis goes beyond simple reading the Reform Treaty and focuses on the perceptions and expectations towards the Rotating Presidency (as understood by the logic of appropriateness). The change of perceptions regarding the roles of the Rotating Presidency is seen in relation to the level of the council system and its field of competence. As a re…

Safety of Tyrosine Kinase Inhibitors in Patients With Differentiated Thyroid Cancer: Real-World Use of Lenvatinib and Sorafenib in Korea

2019

Background: Thyroid cancer has become the most common cancer in Korea. Generally, thyroid cancer patients have a good prognosis; however, 15–20% of patients experience recurrence or distant metastasis or are refractory to standard treatment. We assessed the safety of sorafenib and lenvatinib in patients with advanced or metastatic radioactive iodine-refractory differentiated thyroid cancers (DTC) consecutively treated at a tertiary center in South Korea.Methods: We retrospectively reviewed the charts of all consecutive patients with DTC treated during ≥6 months with lenvatinib (February 2016–April 2018) and sorafenib (January 2014–April 2018) at Gangnam Severance Hospital. Patients were tre…

Schooling effects and earnings of French University graduates: school quality matters, but choice of discipline matters more

2010

Our aim in this article is to study the relation between earnings of French universities graduates and some characteristics of their universities. We exploit data from the Céreq's "Génération 98" survey, enriched with information on university characteristics primarily from the ANETES (yearbook of French institutions of higher education). We employ multilevel modeling, enabling us to take advantage of the natural hierarchy in our separate datasets, and thus to identify, and even to measure potential effects of institutional quality. Since we take into account many individual students characteristics, we are able to obtain an income hierarchy among the different disciplines : students who gr…

The Assessment of Self-Other Differentiation: A Contribution to the Italian Validation of the “Self-Other Differentiation Scale”.

2018

Emotional Profile and Intellectual Functioning

2015

Insufficient literature has been produced addressing children with borderline intellectual functioning (BIF) and gifted intellectual functioning (GIF). The goal of this work is to compare levels of self-esteem, depression, anxiety at school, and insecurity among children with BIF and GIF, and a control group of average intellectual functioning (AIF). There were participants of 104 children (fourth grade of primary school). Analyses revealed that children with BIF showed a lower level of self-esteem and higher levels of depression and school anxiety. Moreover, our findings highlight the co-occurrence of school anxiety, depressed mood, and insecurity among the BIF and AIF groups. One of the …

Recalled parental rearing style, self-esteem, and psychopathological symptoms in the general population

2020

The enduring impact of perceived parental behavior on self-esteem as well as anxiety and depression in adults is still unknown. In a large random route sample (age range 18?92), 4,747 subjects were asked to complete questionnaires about recalled parental rearing, selfesteem, anxiety, and depression. Structural equation modeling was used, and the data from the mother and the father version of the FEE (a questionnaire for recalled parental rearing) were analyzed separately. A model proposing that self-esteem mediates the relationship between parental behavior and psychopathological symptoms fits the data rather well (CFI = .95, RMSEA = .05, TLI = .94). Hence, the recalled authoritative parent…

Inny/obcy: doświadczenie języka i rzeczywistości (literacko-kulturowa ponowoczesność)

2017

The subject matter is developed around the Other, their presence and their personalising in the literary-cultural space. The reality becomes the source of observation (fiction and non-fiction) and reveals not only a variety of human experience in the world of multiculturalism, but also forms of “branding” the Other (rhetoric of the dominant communities towards cultural minorities) which correspond to them. The analysis of the rhetoric of speech and image permits to reveal the good and the bad side of language-cultural stereotypes, including also attitudes and behaviours affected by ideology.