Search results for "Diol"

showing 10 items of 11756 documents

Does angiotensin-converting enzyme gene polymorphism affect blood pressure? Findings after 6 years of follow-up in healthy subjects.

2003

Background: There has been an increase in research into the association between angiotensin-converting enzyme (ACE) gene deletion polymorphism and cardiovascular disease, with conflicting results. The present prospective long-term study was conducted to evaluate whether the DD genotype could also be associated with a higher prevalence of hypertension in healthy subjects, over 6 years of follow-up. Methods: Population: 684 healthy volunteers (aged, 25–55 years): normotensive and free of cardiovascular diseases, with acceptable echocardiographic window. All subjects had to have a normal electrocardiogram (ECG) and echocardiogram (ECHO) at entry. Study protocol: All subjects underwent a comple…

AdultMaleACE-I/D gene polymorphismmedicine.medical_specialtyTime FactorsGenotypePopulationBlood PressurePeptidyl-Dipeptidase AReference ValuesInternal medicineMedicineHumansProspective StudiesFamily historyeducationeducation.field_of_studyPolymorphism Geneticbiologybusiness.industryIncidence (epidemiology)IncidenceAngiotensin-converting enzymeVenous bloodMiddle Agedmedicine.diseaseMutagenesis InsertionalEndocrinologyBlood pressureHeart failureHypertensionbiology.proteinFemaleGene polymorphismCardiology and Cardiovascular MedicinebusinessHealthy subjectGene DeletionFollow-Up StudiesEuropean journal of heart failure
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Assessment of EVAR Complications using CIRSE Complication Classification System in the UK Tertiary Referral Centre: A ∼6-Year Retrospective Analysis …

2021

Purpose: To retrospectively analyse complications in endovascular aortic repair (EVAR) interventions and evaluate if the CIRSE (Cardiovascular and Interventional Radiological Society of Europe) complication classification system is appropriate as a standardized classification tool for EVAR patients. Materials and Methods: Demographic, procedural and complication data in 719 consecutive patients undergoing EVAR at one institution from January 2014 to October 2019 were retrospectively reviewed. Data (imaging reports, procedural reports, nurse notes, discharge summary reports) were collected consulting the electronic patient record system (EPR) of the hospital and cleaned and stored in a Micro…

AdultMaleAccess-site complicationmedicine.medical_specialtyTime FactorsAdditional treatmentEndoleakEndovascular aortic repair (EVAR)Tertiary referral centreComplication grading scalePopulationVascular accessRadiology InterventionalSeverity of Illness Index030218 nuclear medicine & medical imagingTertiary Care Centers03 medical and health sciencesYoung Adult0302 clinical medicinePostoperative ComplicationsmedicineRetrospective analysisHumansRadiology Nuclear Medicine and imagingIn patienteducationReferral and ConsultationSocieties MedicalAgedRetrospective StudiesAged 80 and overeducation.field_of_studyCIRSE complication classification systemmedicine.diagnostic_testbusiness.industryGeneral surgeryEndovascular ProceduresInterventional radiologyMiddle AgedUnited KingdomAortic AneurysmEuropeReporting systemTreatment OutcomeRadiological weaponFemaleCardiology and Cardiovascular MedicineComplicationbusinessCardiovascular and interventional radiology
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Dynamic accommodation without feedback does not respond to isolated blur cues

2016

Highlights • A new methodology is used to study a potential cue for dynamic accommodation. • We show that human accommodation is not driven correctly by defocus alone. • Accommodation is most efficient using changes in stimulus vergence with feedback.

AdultMaleAccommodationmedicine.medical_specialtygenetic structuresComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONAudiologyStimulus (physiology)Article050105 experimental psychologyPupilDynamic accommodationYoung Adult03 medical and health sciences0302 clinical medicineOpticsVergencemedicineHumans0501 psychology and cognitive sciencesMaltese crossbusiness.industry05 social sciencesHealthy subjectsAccommodation OcularBiofeedback PsychologyRefractive ErrorsSensory SystemsOphthalmologyAberrations of the eyeSpherical aberration030221 ophthalmology & optometryFemalesense organsCuesbusinessPsychologyHigher-order aberrationsAccommodationVision Research
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Association between antithrombotic treatment and outcomes at 1-year follow-up in patients with atrial fibrillation: the EORP-AF General Long-Term Reg…

2019

Aims In recent years, stroke prevention in patients with atrial fibrillation (AF) has radically changed, with increasing use of non-vitamin K antagonist oral anticoagulants (NOACs). Contemporary European data on AF thromboprophylaxis are needed. Methods and results We report 1-year follow-up data from the EURObservational Research Programme in Atrial Fibrillation (EORP-AF) General Long-Term Registry. Outcomes were assessed according to antithrombotic therapy. At 1-year follow-up, 9663 (88.0%) patients had available data for analysis: 586 (6.1%) were not treated with any antithrombotic; 681 (7.0%) with antiplatelets only; 4066 (42.1%) with vitamin K antagonist (VKA) only; 3167 (32.8%) with …

AdultMaleAcute coronary syndromemedicine.medical_specialtymedicine.drug_classHemorrhageOutcomes030204 cardiovascular system & hematologyLower riskRisk Assessment[SHS]Humanities and Social Sciences03 medical and health sciences0302 clinical medicineFibrinolytic AgentsRisk FactorsPhysiology (medical)Internal medicineCause of DeathAntithromboticMedicineHumans030212 general & internal medicineProspective StudiesRegistriesPractice Patterns Physicians'StrokeAgedEORP-AF registryAged 80 and overAntithrombotic therapybusiness.industryProportional hazards modelAtrial fibrillationVitamin K antagonistMiddle Agedmedicine.diseaseAtrial fibrillationObservational registriesEuropeStrokeFemaleCardiology and Cardiovascular MedicinebusinessAntithrombotic therapy; Atrial fibrillation; EORP-AF registry; Observational registries; Outcomes; StrokeFibrinolytic agentFollow-Up Studies
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Virtual endoscopy of the inner ear and the auditory canal.

2000

To assess the role of virtual endoscopy (VE) in the examination of intracisternal structures and of the inner ear, we studied the anatomy of the labyrinth and internal auditory canal using the original CT slices and VE on the unaffected side in three female and three male patients, age range 3–46 years, with contralateral retrocochlear hearing loss. We also examined seven patients with different pathological findings. VE was performed using an advanced postprocessing program with high- resolution 3D data sets of CT (1–1.5 mm thickness, pitch 1.25) and MRI-CISS-3D (constructive interference in steady state) images of the basal cisterns (1.5 T, slice thickness 0.7–1 mm). VE provides an endosc…

AdultMaleAdolescentAuditory canalUser-Computer InterfaceImaging Three-DimensionalInternal auditory meatusReference ValuesmedicineHumansRadiology Nuclear Medicine and imagingInner earVirtual endoscopyChildNeuroradiologymedicine.diagnostic_testbusiness.industryCisternMagnetic resonance imagingEndoscopyAnatomyNeuroma AcousticMiddle AgedCochlear ImplantationEndoscopymedicine.anatomical_structureChild PreschoolEar InnerFemalesense organsNeurology (clinical)Cardiology and Cardiovascular MedicinebusinessNeuroradiology
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Observations of time-based measures of flow-mediated dilation of forearm conduit arteries: implications for the accurate assessment of endothelial fu…

2010

Endothelium-dependent flow-mediated dilation (FMD) is measured as the increase in diameter of a conduit artery in response to reactive hyperemia, assessed either at a fixed time point [usually 60-s post-cuff deflation (FMD60)] or as the maximal dilation during a 5-min continuous, ECG-gated, measurement (FMDmax-cont). Preliminary evidence suggests that the time between reactive hyperemia and peak dilation (time to FMDmax) may provide an additional index of endothelial health. We measured FMDmax-cont, FMD60, and time to FMDmax in 30 young healthy volunteers, 22 healthy middle-aged adults, 16 smokers, 23 patients with hypertension, 40 patients with coronary artery disease, and 22 patients wit…

AdultMaleAdolescentBrachial ArteryEndotheliumPhysiologyCoronary Artery DiseaseElectrical conduitForearmPhysiology (medical)medicineHumanscardiovascular diseasesEnzyme InhibitorsReactive hyperemiaHeart FailureAnalysis of Variancebusiness.industrySmokingMiddle AgedVasodilationNG-Nitroarginine Methyl Estermedicine.anatomical_structureRegional Blood FlowAnesthesiaHypertensionCirculatory systemcardiovascular systemDilation (morphology)FemaleEndothelium VascularCardiology and Cardiovascular MedicinebusinessBlood vesselArteryAmerican Journal of Physiology-Heart and Circulatory Physiology
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Erratum to typical asymmetry in the hemispheric activation during an fMRI verbal comprehension paradigm is related to better performance in verbal an…

2019

Chronic exposure to seizures in patients with left hemisphere (LH) epileptic focus could favor higher activation in the contralateral hemisphere during language processing, but the cognitive effects of this remain unclear. This study assesses the relationship between asymmetry in hemispheric activation during language fMRI and performance in verbal and non-verbal tasks. Whereas prior studies primarily used fMRI paradigms that favor frontal lobe activation and less prominent activation of the medial or superior temporal lobes, we used a verbal comprehension paradigm previously demonstrated to activate reliably receptive language areas. Forty-seven patients with drug-resistant epilepsy candid…

AdultMaleAdolescentCognitive NeuroscienceArticleFunctional LateralityNonverbal communicationEpilepsyYoung AdultText miningCognitionmedicineHumansRadiology Nuclear Medicine and imagingVerbal comprehensionIn patientLanguageBrain MappingEpilepsybusiness.industrymedicine.diseaseMagnetic Resonance ImagingNeurologyFemaleNeurology (clinical)businessPsychologyComprehensionCognitive psychologyNeuroImage : Clinical
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Retrospective study of a series of 850 patients with temporomandibular dysfunction (TMD). Clinical and radiological findings

2009

Objective: To define the clinical and radiological characteristics of the four most common presentations of temporomandibular dysfunction-myofascial pain (MFP), disc displacement with reduction (DDWR), disc displacement without reduction (DDWoR), and osteoarthrosis (OR)-and to identify the differences among them. Material and methods: The study comprised a series of 850 patients (121 males and 729 females) seen between May 2003 and December 2006 in Valencia University General Hospital (Spain) for temporomandibular joint disease (TMJD). An analysis was made of the possible etiological factors (stress, traumatisms, sleep disturbances, parafunctional habits, reason for consultation), possible …

AdultMaleAdolescentDentistryPalpationYoung AdultPost-hoc analysismedicineHumansGeneral DentistryAgedRetrospective StudiesAged 80 and overmedicine.diagnostic_testbusiness.industryRetrospective cohort studyMiddle AgedTemporomandibular Joint Disorders:CIENCIAS MÉDICAS [UNESCO]Temporomandibular jointMasticatory forceRadiographymedicine.anatomical_structureOtorhinolaryngologyRadiological weaponUNESCO::CIENCIAS MÉDICASLigamentEtiologySurgeryFemalebusiness
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Retrospective clinicopathological study of 418 odontogenic cysts

2010

Objectives: To determine the relative incidence of odontogenic cysts and to identify the main clinicopathological features among patients treated in the Oral Surgery Department of the Dental Clinic of the University of Barcelona (Spain). Study design: A retrospective observational study was made of 418 odontogenic cysts diagnosed in 380 patients included in the database of 1235 histopathological diagnoses. The subjects were treated in the Master degree program of Oral Surgery and Implantology of the University of Barcelona in the period 1997-2006. The following variables were recorded: gender, age, clinical characteristics of the lesions (size and location), radiological features, duration,…

AdultMaleAdolescentEarly detectionDentistryOdontologiaQuistosLesionYoung AdultOral surgeryPrevalencemedicineHumansChildGeneral DentistryAgedRetrospective StudiesAged 80 and overRadicular CystCirurgia oralbusiness.industryIncidence (epidemiology)Retrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]OdontogenicCysts (Pathology)OtorhinolaryngologyDental clinicDentistryRadiological weaponOdontogenic CystsUNESCO::CIENCIAS MÉDICASFemaleSurgerymedicine.symptombusinessMedicina Oral Patología Oral y Cirugia Bucal
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Influential Periods in Longitudinal Clinical Cardiovascular Health Scores

2021

Abstract The prevalence of ideal cardiovascular health (CVH) among adults in the United States is low and decreases with age. Our objective was to identify specific age windows when the loss of CVH accelerates, to ascertain preventive opportunities for intervention. Data were pooled from 5 longitudinal cohorts (Project Heartbeat!, Cardiovascular Risk in Young Finns Study, The Bogalusa Heart Study, Coronary Artery Risk Development in Young Adults, Special Turku Coronary Risk Factor Intervention Project) from the United States and Finland from 1973 to 2012. Individuals with clinical CVH factors (i.e., body mass index, blood pressure, cholesterol, blood glucose) measured from ages 8 to 55 year…

AdultMaleAdolescentEpidemiologyCardiovascular healthHealth Behavior3121 Internal medicineYoung AdultSex Factorscohort studiespreventionHumanslongitudinal studiesrisk factorsMedicineAcademicSubjects/MED00860Young adultChildAgedbusiness.industryAge Factorscardiovascular healthOriginal ContributionMiddle AgedLate adolescence3126 Surgery anesthesiology intensive care radiologyMiddle ageConfidence interval3142 Public health care science environmental and occupational healthBlood pressureHeart Disease Risk FactorsFemaleadolescencebusinessBody mass indexcardiovascular epidemiologyDemographyCohort study
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