Search results for "Diss"
showing 10 items of 2500 documents
Solid microcrystalline dispersion films as a new strategy to improve the dissolution rate of poorly water soluble drugs: A case study using olanzapine
2016
In this study, we evaluate the dissolution rate enhancement of solid microcrystalline dispersion (SMD) films of olanzapine (OLZ) formulated with four water-soluble polymers namely poly(N-vinylpyrrolidone) (PVP), poloxamer 188 (P188), poloxamer 407 (P407) and Soluplus(®) (SLP). Prepared formulations were characterised to determine particle size, morphology, hydrogen bonding interactions, thermal characteristics as well as in vitro dissolution studies conducted under sink conditions (pH 6.8). Particle size of OLZ in all formulations ranged between 42 and 58μm. Attenuated Total Reflectance Fourier Transform Infrared spectroscopy (ATR-FTIR), Differential Scanning Calorimetry (DSC) and Hot-Stage…
Real-time simulation of tissue deformation for the nasal endoscopy simulator (NES).
1999
Endonasal sinus surgery requires a great amount of training before it can be adequately performed. The complicated anatomy involved, the proximity of relevant structures, and the variability of the anatomy due to inborn or iatrogenic variations make several complications possible. Today, cadaver dissections are the "gold standard" for surgical training. To overcome the drawbacks of traditional training methods, the Fraunhofer Institute for Computer Graphics is currently developing a highly interactive medical simulation system for nasal endoscopy and endonasal sinus surgery, in cooperation with the Mainz University Hospital. For the simulation of a rhinoscopic procedure, not only are the re…
Surface charges at the CaF2/water interface allow very fast intermolecular vibrational-energy transfer
2020
Abstract We investigate the dynamics of water in contact with solid calcium fluoride, where at low pH, localized charges can develop upon fluorite dissolution. We use 2D surface‐specific vibrational spectroscopy to quantify the heterogeneity of the interfacial water (D2O) molecules and provide information about the sub‐picosecond vibrational‐energy‐relaxation dynamics at the buried solid/liquid interface. We find that strongly H‐bonded OD groups, with a vibrational frequency below 2500 cm−1, display very rapid spectral diffusion and vibrational relaxation; for weakly H‐bonded OD groups, above 2500 cm−1, the dynamics slows down substantially. Atomistic simulations based on electronic‐structu…
Thermomineral waters of Greece: geochemical characterization
2020
Fiscality of couples in fact
2019
[ES] Las parejas de hecho son una unión alternativa al matrimonio y, como tal, el ordenamiento les dedica un régimen jurídico. El presente estudio trata sobre la fiscalidad que rodea a estas uniones partiendo siempre de su situación patrimonial y los acuerdos alcanzados entre los convivientes. Se analiza el encaje dentro del IRPF de la pareja de hecho y la aplicación de las circunstancias personales y familiares a los convivientes. Asimismo, se tratará la aportación de éstos a la comunidad de bienes formada por ambos y la adquisición de bienes una vez constituida la misma. Todo ello desde la aplicación de los impuestos que gravan la transmisión o adquisición de bienes, ya sea de forma onero…
Jurisdiction by connection and proper administration of justice under eu regulations 1103/2016 and 1104/2016
2021
The author analyses the rules of jurisdiction by connection set by Articles 4 and 5 of Regulations No. 1103 and 1104 of 2016 in matters of property regimes of transnational couples, taking into account the objective of proper administration of justice pursued within EU Civil judicial cooperation. The Twin Regulations provide for appropriate procedural tools to facilitate concentration of jurisdiction before the courts of the same Member State, establishing an important role for the choice-of-court agreement, especially where property regime issues arise in connection with a matrimonial case or a partnership dissolution case. As we wait for the implementation of these rules by national and E…
El disseny físic de les séquies valencians durant els segles XVI-XVIII
2017
Heliodor, Etiòpiques VI 14-15: un cas únic de necromància a la novel·la grega antiga
2014
La tradició literària que hi ha al darrere de la novel·la d'Heliodor Teàgenes i Cariclea és abundant en obres i en gèneres, però especialment deutora de l'Odissea d'Homer. L'únic passatge de necromància de la novel·la grega antiga també presenta, i de manera molt evident i curiosa, aquesta intertextualitat, oferint importants punts en contacte amb la nékyia del cant XI de l'obra homèrica. Així mateix, remet als ritus egipcis que descriu Heròdot al llibre II de la seua Història i al d'Els perses d'Èsquil per convocar el fantasma de Darios. Es tracta d'un passatge singular amb motius de la literatura grega precedent. The literary tradition which underlies to the Heliodorus' roman Theagenes an…
La Repubblica di Platone fra totalitarismo, dissimulazione e utopia
2014
Microbiology and atmospheric processes: research challenges concerning the impact of airborne micro-organisms on the atmosphere and climate
2011
Cet article a fait l'objet d'une discussion dans "Morris, C. E., Sands, D. C., Bardin, M., Jaenicke, R., Vogel, B., Leyronas, C., Ariya, P. A., and Psenner, R.: Microbiology and atmospheric processes: an upcoming era of research on bio-meteorology, Biogeosciences Discuss., 5, 191-212, doi:10.5194/bgd-5-191-2008, 2008."; International audience; For the past 200 years, the field of aerobiology has explored the abundance, diversity, survival and transport of micro-organisms in the atmosphere. Micro-organisms have been explored as passive and severely stressed riders of atmospheric transport systems. Recently, an interest in the active roles of these micro-organisms has emerged along with prop…