Search results for "Dithiocarb"

CCDC 139090: Experimental Crystal Structure Determination

2001

Related Article: G.Sanchez, F.Ruiz, J.L.Serrano, M.C.Ramirez de Arellano, G.Lopez|2000|Eur.J.Inorg.Chem.||2185|doi:10.1002/1099-0682(200010)2000:10<2185::AID-EJIC2185>3.0.CO;2-K

Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers.

2003

Strong contact sensitizers are able to induce signal transduction mechanisms such as tyrosine phosphorylation and activation of MAP kinases in antigen-presenting cells. We studied the capacity of different antioxidants (ascorbic acid, alpha-tocopherol, pyrrolidine dithiocarbamate, N-acetylcysteine, and glutathione) to block the increase in tyrosine phosphorylation in human monocytes seen after stimulation with strong contact sensitizers. Human peripheral blood mononuclear cells were stimulated with 5-chloro-2-methylisothiazolinone plus 2-methylisothiazolinone in the presence or absence of these antioxidants. The total amount of membrane-associated phosphotyrosine in CD14+ cells was quantifi…

Multi-elemental determination of heavy elements in plastics using X-ray fluorescence after destruction of the polymer by molten sodium hydroxide

1992

In this paper a method is proposed for the multielemental analysis of Sb(III), Ba, Cd, Cr(III), Hg, Pb and As(III) in plastics, using X-ray fluorescence after alkaline decomposition and preconcentration by (co)precipitation. The organic matrix is destroyed by decomposition with sodium hydroxide melted in a silver crucible by the open system technique, using sodium nitrate as auxiliary oxidant. The variables which influence preconcentration are optimized: digestion time, pH, salinity, carrier and sodium diethyldithiocarbamate (DDTC) and sodium rhodizonate (R) as precipitants. The calibration curves were linear up to 200 μg of the element present, except for lead (150 μg) antimony(III) (100 μ…

Fourier transform infrared spectrometric determination of Ziram.

2001

A procedure has been developed for vapour-phase Fourier transform infrared determination of Ziram, a dithiocarbamate pesticide. The method is based on the evolution of CS(2), after decomposition of the dithiocarbamate with diluted H(2)SO(4) at 50 degrees C. The CS(2) evolved was swept by a carrier flow of nitrogen to a laboratory-made infrared gas cell of 39 mm pathlength and 490 mul volume. The signals were registered as a function of time. The area of peaks obtained from absorbance measurement in the wavenumber range between 1600 and 1450 cm(-1) were interpolated in a calibration line established from Ziram standards treated in the same way as samples. The method provided an absolute limi…

Zum metabolismus von dialkyldithiocarbamaten

1974

Abstract Metabolism dialkyldithiocarbamates. I. Determination of amines using a reaction with isocyanates followed by gas chromatographic identification of the urea derivatives formed. N,N′-Di- and N,N′,N′-trisubstituted areas, formed by the reaction of amines with isocyanates, e.g. tert. -butyl isocyanate or 3-trifluoromethylphenyl isocyanate, are useful derivatives for the gas chromatographic analysis of primary and secondary amines. The separation is carried out at temperatures between 70 and 130° on liquid phases such as silicone OV-101 and silicone OV-17. With nitrogen and electron capture detectors the detection limit is 10 10 g. Trace analysis of simple primary and secondary amines i…

Organometallic Nickel(II) Complexes Containing Thiolate and Dithiocarbamate Ligands

2000

Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle.

2004

Two studies were performed to investigate the effects of an acute bout of physical exercise on the nuclear protein kappaB (NF-kappaB) signaling pathway in rat skeletal muscle. In Study 1, a group of rats (n=6) was run on the treadmill at 25 m/min, 5% grade, for 1 h or until exhaustion (Ex), and compared with a second group (n=6) injected with two doses of pyrrolidine dithiocarbamate (PDTC, 100 mg/kg, i.p.) 24 and 1 h prior to the acute exercise bout. Three additional groups of rats (n=6) were injected with either 8 mg/kg (i.p.) of lipopolysaccharide (LPS), 1 mmol/kg (i.p.) t-butylhydroperoxide (tBHP), or saline (C) and killed at resting condition. Ex rats showed higher levels of NF-kappaB b…

Determination of organic and inorganic mercury species in water and sediment samples by HPLC on-line coupled with ICP-MS.

2009

This paper describes a preconcentration method for Hg(2+) and MeHg(+) in water samples using sodium diethyldithiocarbamate immobilized in polyurethane foam (PU-NaDDC) and an extraction method for several mercury species in sediment samples, including MeHg(+), EtHg(+) and PhHg(+), which is simple, rapid, and uses a single organic solvent. Separation and measurement were done by high-performance liquid chromatography on-line with inductively coupled plasma mass spectrometry (HPLC/ICP-MS). Initially, the test of recovery was applied using procedures compatible with HPLC. Under the optimum extraction conditions, recoveries of 96.7, 96.3 and 97.3% were obtained for MeHg(+), EtHg(+), and PhHg(+),…

Synthesis of Both Ionic Species of Ammonium Dithiocarbamate Derived Cholic Acid Moieties

2011

The reaction of 3-aminopropylamide of cholic acid with CS2 produced a bile acid derivative of dithiocarbamic acid which further formed an ammonium salt with another molecule of 3-aminopropylamide of cholic acid. The cationic 3-ammonium propylamide of cholic acid did not react further with CS2 and the formed salt was stable in the reaction mixture, even when excess CS2 was used. When the reaction was carried out in the presence of aqueous sodium hydroxide, only the bile acid derivative of sodium dithiocarbamate was formed. The dithiocarbamate derivatives were characterized by 1H- and 13C-NMR spectroscopy and ESI-TOF mass spectrometry.

Irreversible protein binding of acrylonitrile.

1981

1. After i.p. injection of [2,3-14C]acrylonitrile to rats, a significant portion of radioactivity becomes irreversibly attached to proteins of liver, lung, spleen and other tissues. 2. When rat liver microsomes were incubated with [2,3-14C]acrylonitrile, a time-dependent irreversible binding of radioactivity occurred to microsomal proteins. This binding was not dependent on NADPH. A high extent of binding to heat-inactivated microsomes indicated that no enzymic metabolic step was involved. 3. The irreversible binding of [2,3-14C]acrylonitrile to rat liver microsomal protein in vitro was inhibited by thiols (cysteine, glutathione, mercaptoethanol). The greatest inhibitory potency was display…