Search results for "Dog"
showing 10 items of 1087 documents
Polygenic association between attention-deficit/hyperactivity disorder liability and cognitive impairments.
2022
AbstractBackgroundA recent genome-wide association study (GWAS) identified 12 independent loci significantly associated with attention-deficit/hyperactivity disorder (ADHD). Polygenic risk scores (PRS), derived from the GWAS, can be used to assess genetic overlap between ADHD and other traits. Using ADHD samples from several international sites, we derived PRS for ADHD from the recent GWAS to test whether genetic variants that contribute to ADHD also influence two cognitive functions that show strong association with ADHD: attention regulation and response inhibition, captured by reaction time variability (RTV) and commission errors (CE).MethodsThe discovery GWAS included 19 099 ADHD cases …
A ceRNA analysis on LMNA gene focusing on the Hutchinson-Gilford progeria syndrome
2013
Background: Hutchinson-Gilford progeria syndrome is a rare dominant human disease of genetic origin. The average life expectancy is about 20 years, patients’ life quality is still very poor and no efficient therapy has yet been developed. It is caused by mutation of the LMNA gene, which results in accumulation in the nuclear membrane of a particular splicing form of Lamin-A called progerin. The mechanism by which progerin perturbs cellular homeostasis and leads to the symptoms is still under debate. Micro-RNAs are able to negatively regulate transcription by coupling with the 3’ UnTranslated Region of messenger RNAs. Several Micro-RNAs recognize the same 3’ UnTranslated Region and each Micr…
Croissance endogène et économie géographique
1998
International audience
Il diritto delle obbligazioni nel pensiero di Adolfo di Majo. A margine di Obbligazioni e tutele.
2020
Il saggio ripercorre il fondamentale contributo degli studi del prof. Adolfo di Majo al diritto delle obbligazioni. L'attenzione del prof. di Majo si è soffermata su tutti i principali aspetti del diritto delle obbligazioni, con speciale riferimento al versante dei rimedi: adempimento in natura, risarcimento del danno, risoluzione. Il prof. di Majo può essere considerato il principale esponente della corrente di pensiero volta a valorizzare la fase delle tutele, intesa come fase autonoma del fenomeno giuridico. Il metodo adottato dal prof. di Majo è senza dubbio dogmatico, ma si tratta di una dogmatica temperata dall'attenzione alla dimensione materiale degli interessi. E ciò ha indotto l'a…
Biblijne i dogmatyczne podstawy nauki o szatanie oraz współczesne kryteria jej oceny
2018
Starożytny Wschód przypisywał personalny charakter tysiącom tajemniczych sił, których obecność wiązano z wszelkim złem, jakie nawiedza człowieka. Także w Biblii mówi się nie tylko o dobrych istotach duchowych – aniołach, ale i o takich, które szkodzą ludziom, przynoszą choroby i kuszą do złego. Duchy te nazywano demonami, a ich przywódcę szatanem lub diabłem. Artykuł w czterech punktach ukazuje biblijną naukę o demonach i szatanie, główne trendy rozwoju tej nauki w historii myśli chrześcijańskiej oraz kryteria stosowane we współczesnej hermeneutyce związanej z biblijnymi tekstami o demonach i szatanie.
Tarantino's Round Flat Characters: A (Mainly) Verbal Study of Reservoir Dogs (1992).
2012
International audience; This article revisits E.M. Forster's distinction between round and flat characters in order to study the balancing between genre characters and realistic characters Tarantino's first film effects. It starts by examining the relationship between the fictional director of the heist (Joe Cabot), the other characters and the real director in a scene where Tarantino's cameo as a minor character endows the fictional director with authority and consequently emphasizes the shared dimension of filmmaking. The author then argues that the characters' capacity to identify and articulate flatness and rotundity in themselves and each other makes them appear round as it implies tha…
The endogeneous nature of the dynamic analysis among classical economist's writings
1998
« Endogenous growth theories » exhibit different models in which growth is assumed to come from the accumulation of a particular factor (human capital, technology, public infrastructures, etc.). However, due to its newness, the real term of « endogenous growth » seems to playdown old theories.This paper intends to put right this position and demonstrate that relations displayed by current models are only formalizations stemming from the developments of classical economists. In the end, we demonstrate that their analysis yields new viewpoints for analysts. Overall, we wish to reinforce theendogenous nature of the dynamic analysis among classical economist's writings.
Epistemologia metodologica e prassi operativa. Benefici e applicazioni nei contesti comunitari residenziali
2019
Alcune ricerche sostengono che l’animale, nella sua diversità sia morfologica che comportamentale, solleciti nel bambino la formazione e lo sviluppo dell’immaginario, attraverso l’offerta di più modelli per i suoi processi elaborativi e il rafforzamento della sua fantasia ( Piccino, 2014). L’animale svolge un ruolo formativo importante nello sviluppo mentale dei bambini, inoltre interagire con la diversità di cui l’animale è costituito o il semplice riferirsi alla diversità dell’animale, aiuterebbe il bambino a trasformare la differenza in curiosità e tolleranza. Attraverso specifiche attività che implicano una relazione positiva, gli interventi assistiti con gli animali possono veicolare l…
Ratures fécondes
2012
Commenting on daily life of the scientific community, newspapers highlight some characteristics of the way sciences are evolving, thanks to a kind of epistemological flash-back : the way they lean on working hypothesis, these working hypothesis leaning themselves on on-going dogma. These comments on scientific current affairs call for a new understanding of gradual corrections of hypothesis.
CoproID predicts the source of coprolites and paleofeces using microbiome composition and host DNA content
2020
Shotgun metagenomics applied to archaeological feces (paleofeces) can bring new insights into the composition and functions of human and animal gut microbiota from the past. However, paleofeces often undergo physical distortions in archaeological sediments, making their source species difficult to identify on the basis of fecal morphology or microscopic features alone. Here we present a reproducible and scalable pipeline using both host and microbial DNA to infer the host source of fecal material. We apply this pipeline to newly sequenced archaeological specimens and show that we are able to distinguish morphologically similar human and canine paleofeces, as well as non-fecal sediments, fro…