Search results for "Dones"
showing 10 items of 338 documents
Folliculotropic Mycosis Fungoides With Flexural Eruptive Cysts and Comedones in a 14-Year-Old Boy
2021
Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation
2019
Background: Appropriate antithrombotic regimens for patients with atrial fibrillation who have an acute coronary syndrome or have undergone percutaneous coronary intervention (PCI) are unclear. Methods: In an international trial with a two-by-two factorial design, we randomly assigned patients with atrial fibrillation who had an acute coronary syndrome or had undergone PCI and were planning to take a P2Y12 inhibitor to receive apixaban or a vitamin K antagonist and to receive aspirin or matching placebo for 6 months. The primary outcome was major or clinically relevant nonmajor bleeding. Secondary outcomes included death or hospitalization and a composite of ischemic events. Results: Enroll…
Potential Myocardial Iron Content Evaluation by Magnetic Resonance Imaging in Thalassemia Major Patients Treated with Deferoxamine or Deferiprone Dur…
2003
The purpose of this study was to evaluate if the variations of heart magnetic resonance imaging in beta-thalassemia major patients treated with Deferoxamine B mesylate (DF) or Deferiprone (L1) chelation therapy is a useful tool of the indirect myocardial iron content determination. For this reason, a prospective study was carried out. Seventy-two consecutive patients with beta-thalassemia major (35 treated with DF and 37 with L1) were studied. The main outcome results were laboratory parameters including determination of the liver iron concentration (LIC) and magnetic resonance imaging (MRI) of the heart and liver. The heart to muscle signal intensity ratios (HSIRs) were significantly incre…
Use of direct oral anticoagulants in very elderly patients: a case report of apixaban in an ultracentenary patient.
2019
no
COVID-19 in people living with HIV: Clinical implications of dynamics of the immune response to SARS-CoV-2.
2020
ABSTRACT Background Little evidence on COVID‐19 in people living with HIV (PLWH) is currently available. Material and Methods We reported clinical and viro‐immunological data of all HIV‐positive patients admitted to our centre with COVID‐19 from March 1 to May 12,2020. Results Overall, five patients were included: all were virologically‐suppressed on antiretroviral therapy and CD4+ count was >350 cell/mm3 in all but two patients. Although all patients had evidence of pneumonia on admission, only one developed respiratory failure. SARS‐CoV‐2‐RNA was never detected from nasopharyngeal swabs in two patients, whereas, in the others, viral clearance occurred within a maximum of 43 days. IgG prod…
Dispacamide E and other bioactive bromopyrrole alkaloids from two Indonesian marine sponges of the genus Stylissa.
2014
Chemical investigation of methanolic extracts of the two Indonesian marine sponges Stylissa massa and Stylissa flabelliformis yielded 25 bromopyrrole alkaloids including 2 new metabolites. The structures of all isolated compounds were unambiguously elucidated based on extensive 1D and 2D NMR, LR-MS and HR-MS analyses. All isolated compounds were assayed for their antiproliferative and protein kinase inhibitory activities. Several of the tested compounds revealed selective activity(ies) which suggested preliminary SARs of the isolated bromopyrrole alkaloids.
Linking female entrepreneurs' motivation to business survival.
2015
Abstract Analysis of entrepreneurs' motives in the framework of organizational behavior theory is a popular research area regarding female entrepreneurship. This study analyzes women entrepreneurs' motives (propensity for risk, finding a work–life balance, desire to develop business skills, need to seek self-employment, and desire to earn more than in paid employment) to achieve survival of their businesses through crisp set qualitative comparative analysis (csQCA). Analysis yields the following results: 1) women whose motive is to pursuit a better work–life balance are less likely to success; and 2) women whose motive is risk-taking are more likely to success.
Safety analysis of the DONES primary heat removal system
2020
Abstract The development of a neutron source able to reproduce the irradiation conditions typical of a nuclear fusion reactor, in order to test candidate structural materials, is the main goal of the Work Package Early Neutron Source (WPENS) of the EUROfusion action. This source, named Demo Oriented NEutron Source (DONES), is a facility where neutrons are produced by means of D-Li interactions. More in detail, a beam of 125 mA deuterium ions at the energy of 40 MeV strikes a lithium jet flowing in a purposely shaped channel in order to obtain an intense and stable neutron flux for the irradiation of material samples. In the framework of these activities, safety analyses are a key aspect in …
Contemporary Portrayals of Women and Feminity. A Case Study of Lifestyle Blogs in the U.S.
2017
This article explores contemporary portrayals of women and femininity in lifestyle blogs written and edited by millennial women in the United States. Based on a sample of three of the most popular lifestyle blogs currently in the U.S. this article attempts to identify and describe current portrayals of women to determine if they support a progressive or a conservative approach to femininity. The study we present in this paper is based on a dual methodology: content analysis and discourse analysis. Content analysis allows us to identify topics covered by the selected life- style blogs and their categorizations (sections in which they are published) whereas the discourse analysis helps determ…