Search results for "Dpp"

showing 10 items of 168 documents

Almond (Prunus dulcis cv. Casteltermini) Skin Confectionery By-Products: New Opportunity for the Development of a Functional Blackberry (Rubus ulmifo…

2021

This work proposes for the first time a model for reusing almond (Prunus dulcis cv. Casteltermini from Sicily, Southern Italy) skin to formulate a new functional blackberry (Rubus ulmifolius Schott) jam. For this purpose, blackberries were analysed fresh and as jam, traditionally prepared with a minimum fruit amount of 80%. Different percentages of almond skin (20, 15, and 10% w/w) were added to jam. The phytochemical profile of enriched jam was investigated by LC-ESI/LTQOrbitrap/MS analyses. Anthocyanins, hydrolysable tannins, and triterpenoids were identified in a blackberry extract, while proanthocyanidins, flavonoids, and oxylipins were identified in an almond extract. The n-hexane extr…

AntioxidantPhysiologyDPPHmedicine.medical_treatmentClinical BiochemistryRM1-950carbohydrate hydrolysing enzymesPrunus dulcis cv. Casteltermini skin01 natural sciencesBiochemistrySensory analysisArticlechemistry.chemical_compound0404 agricultural biotechnologylipasemedicineGC–MS<i>Prunus dulcis</i> cv. Casteltermini skinFood scienceBy-products; Carbohydrate hydrolysing enzymes; GC–MS; LC-ESI/LTQOrbitrap/ MS; Lipase; Prunus dulcis cv. Casteltermini skin; Rubus ulmifolius<i>Rubus ulmifolius</i>by-productsMolecular BiologyLC-ESI/LTQOrbitrap/MSABTSRubus ulmifoliusbiologyChemistryBy-products Carbohydrate hydrolysing enzymes GC–MS LC-ESI/LTQOrbitrap/ MS Lipase Prunus dulcis cv. Casteltermini skin Rubus ulmifoliusfungi010401 analytical chemistryfood and beveragesSettore CHIM/06 - Chimica Organica04 agricultural and veterinary sciencesCell Biologybiology.organism_classification040401 food sciencehumanities0104 chemical sciencesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreePrunus dulcisProanthocyanidinPhytochemicalLC-ESI/LTQOrbitrap/ MSTherapeutics. PharmacologyRubus ulmifoliusAntioxidants
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Delivery of liquorice extract by liposomes and hyalurosomes to protect the skin against oxidative stress injuries.

2015

Liquorice extract, obtained by percolation in ethanol of Glycyrrhiza glabra L. roots, was incorporated in liposomes and hyalurosomes, new phospholipid-sodium hyaluronate vesicles, and their protective effect against oxidative stress skin damages was probed. As a comparison, raw glycyrrhizin was also tested. All the vesicles were small in size (≤ 100 nm), with a highly negative zeta potential ensuring long-term stability, and able to incorporate a high amount of the extract. In vitro tests showed that the liquorice extract loaded in vesicles was able to scavenge DPPH free radical (80% inhibition) and to protect 3T3 fibroblasts against H2O2-induced oxidative stress, restoring the normal condi…

AntioxidantPolymers and PlasticsDPPHmedicine.medical_treatmentAdministration TopicalChemistry PharmaceuticalPharmacologymedicine.disease_causePlant Rootschemistry.chemical_compoundMiceDrug StabilityIn vivoCell MovementMaterials TestingMaterials ChemistrymedicineGlycyrrhizaAnimalsEdemaHyaluronic AcidGlycyrrhizinCell ProliferationSkinLiposomeDrug CarriersbiologyPlant ExtractsOrganic Chemistry3T3 CellsFree Radical Scavengersbiology.organism_classificationOxidative StresschemistryBiochemistryLiposomesGlycyrrhizaFemaleDrug carrierOxidative stressCarbohydrate polymers
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Polyphenols pattern and correlation with antioxidant activities of berries extracts from four different populations of SicilianSambucus nigraL.

2014

Sambucus nigra L. (Caprifoliaceae) is wide spread in temperate and sub-tropical zones. The consumption of its berries has been associated with health benefits especially for its high content of natural antioxidants such as polyphenols, in particular anthocyanins. In this work we investigated the polyphenolic composition and the in vitro antioxidant activities (ABTS, DPPH, BCB and FRAP-ferrozine (FRAP-FZ) assays) of S. nigra berries, collected in four different Sicilian areas (Italy). Elderberries are considered one of the fruits with highest anthocyanins content, the amount of phenolic compounds, other than anthocyanins, is approximately 1.5 times greater than the latter. The LC–MS analyses…

AntioxidantSettore AGR/05 - Assestamento Forestale E SelvicolturaDPPHmedicine.medical_treatmentantioxidant activityPlant ScienceSambucus nigraBiochemistryAntioxidantsAnalytical ChemistryAnthocyaninschemistry.chemical_compoundSambucus nigrapolyphenolic compositionBotanymedicineSambucus nigra berries polyphenolic composition antioxidant activitySettore BIO/15 - Biologia FarmaceuticaFood scienceCaprifoliaceaeChromatography High Pressure LiquidABTSMolecular StructurebiologyChemistryOrganic ChemistryPolyphenolsSettore CHIM/06 - Chimica Organicabiology.organism_classificationlanguage.human_languageItalySambucusPolyphenolFruitlanguageComposition (visual arts)Oxidation-ReductionSicilianberrieNatural Product Research
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Chemical Profiling of Polyfloral Belgian Honey: Ellagic Acid and Pinocembrin as Antioxidants and Chemical Markers

2017

Chemical profiling of northern Belgian polyfloral honeys was performed to analyse their phenolic compound content (flavonoids and phenolic acids). First, samples were subjected to a standard analysis of their physicochemical properties, and then, the phenolic fraction was isolated and analysed using a HPLC/PAD method. All of the tested honeys showed a common and specific phenolic profile that could be the basis for the differentiation of polyfloral honeys of the Antwerp region from other polyfloral honeys. Chromatographic data indicated a high content of ellagic acid (9.13–13.66 mg/100 g honey), as well as the flavonoid pinocembrin (1.60–1.85 mg/100 g honey) in these honeys. Ellagic acid, a…

Antioxidantanimal structuresArticle SubjectDPPHmedicine.medical_treatmentFlavonoid01 natural sciencesHigh-performance liquid chromatographylcsh:Chemistrychemistry.chemical_compound0404 agricultural biotechnologyChemical markermedicineFood scienceChemical compositionchemistry.chemical_classificationPinocembrinChemistry010401 analytical chemistrydigestive oral and skin physiologyfungifood and beverages04 agricultural and veterinary sciencesGeneral Chemistry040401 food science0104 chemical scienceslcsh:QD1-999behavior and behavior mechanismsEllagic acidJournal of Chemistry
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Kundmannia sicula (L.) DC: a rich source of germacrene D

2017

AbstractObjective: Kundmannia sicula is an herbaceous plant belonging to the family Apiaceae and is distributed in the Mediterranean coastal areas where it occurs in arid places. In this work, we have analysed the essential oil distilled from the aerial parts of K. sicula from Sicily (Italy) and its biological activity. Methods: GC-MS was used to analyze the chemical composition, whereas its antioxidant capacity and cytotoxicity on three human tumour cells (A375, MDA MB-231 and HCT 116) were evaluated by DPPH, ABTS, FRAP and MTT methods, respectively. Result: The essential oil resulted very rich of the sesquiterpene hydrocarbon germacrene D (81.2%). Moreover, the K. sicula oil displayed rel…

AntioxidantantioxidantDPPHmedicine.medical_treatmentBiologySesquiterpene01 natural sciencesessential oillaw.inventionchemistry.chemical_compoundlawKundmannia siculaBotanygermacrene DmedicineKundmannia siculaEssential oilABTS010405 organic chemistryChemistry (all)Biological activityGeneral ChemistryHerbaceous plant0104 chemical sciences010404 medicinal & biomolecular chemistrychemistrycytotoxicity
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Antioxidant Properties of a Supercritical Fluid Extract of the Halophyte Mesembryanthemum nodiflorum L. from Sicilian Coasts: Nutraceutical and Cosme…

2020

The aim of this paper was to obtain different extracts from the aerial parts of Mesembryanthemum nodiflorum, comparing traditional extraction (using solvents with increasing polarity such as hexane, ethanol 80%, acetone 70% and water) with an eco-friendly technique (supercritical fluid extraction (SFE))

AntioxidantantioxidantDPPHmedicine.medical_treatmentice plant01 natural sciencesSFEIntegrin 1lcsh:Technologylcsh:Chemistry03 medical and health scienceschemistry.chemical_compoundNutraceuticalSettore AGR/20 - Zoocolturemedicineoxidative stressGeneral Materials ScienceMesembryanthemum nodiflorumFood scienceInstrumentationlcsh:QH301-705.5030304 developmental biologyFluid Flow and Transfer Processes0303 health sciencescell cultureSirt1biologyChemistrylcsh:TProcess Chemistry and TechnologyExtraction (chemistry)General EngineeringSupercritical fluid extractionIntegrin α1biology.organism_classificationlcsh:QC1-9990104 chemical sciencesComputer Science Applications010404 medicinal & biomolecular chemistrylcsh:Biology (General)lcsh:QD1-999Polyphenollcsh:TA1-2040Oxidative strelcsh:Engineering (General). Civil engineering (General)Cosmeceuticallcsh:PhysicsApplied Sciences
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Comparative chemical composition, free radical-scavenging and cytotoxic properties of essential oils of six Stachys species from different regions of…

2009

Abstract The chemical composition of essential oils of six Stachys species, S. cretica L. ssp. vacillans Rech. fil., S. germanica L., S. hydrophila Boiss., S. nivea Labill., S. palustris L. and S. spinosa L., obtained by hydrodistillation, was studied by GC and GC–MS. All the oils have in common a great percentage of fatty acids and esters (24.2–58.5%) and a high amount of sesquiterpenes (16–35.9%), with the exception of the oil from S. palustris , which consisted mainly of carbonylic compounds (25.4%). The antioxidant activity by DPPH test and the antiproliferative activity on a series of human cancer cell lines (C32, amelanotic melanoma and ACHN, renal cell adenocarcinoma) were investigat…

AntioxidantbiologyDPPHmedicine.medical_treatmentGeneral MedicineStachys cretica ssp vacillans S. germanica S. hydrophila S. nivea S. palustris S. spinosa Essential oil Antioxidant activity Cytotoxic activityStachysbiology.organism_classificationAnalytical Chemistrylaw.inventionchemistry.chemical_compoundchemistrylawBotanymedicineMediterranean areaCytotoxic T cellFood scienceChemical compositionScavengingEssential oilFood Science
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Protective Effects of the Hydroethanolic Extract of Fridericia chica on Undifferentiated Human Neuroblastoma Cells Exposed to α-Zearalenol (α-ZEL) an…

2021

Fridericia chica (Bignoniaceae) is a traditional medicinal plant. The aim of this research was to determine the protective effects of the hydroethanolic extract from the F. chica leaves (HEFc) against the cytotoxicity of zearalenone (α-ZEL) and β-ZEL on SH-SY5Y cells. Free radical scavenging activity of HEFc was evaluated using the DPPH method. The cytotoxicity of both zearalenone metabolites and HEFc was examined using MTT test, as was the cytoprotective effects of the HEFc on cells treated with these mycotoxins. The chemical composition of HEFc was determined using UPLC-QTOF-MS/MS. HEFc elicited good DPPH radical scavenging activity following a concentration-dependent relationship. Cells …

AntioxidantextractsbiologyTraditional medicineFridericia chicaDPPHHealth Toxicology and Mutagenesismedicine.medical_treatmentRBignoniaceaeToxicologybiology.organism_classification<i>Fridericia chica</i>protectionchemistry.chemical_compoundchemistryPhytochemicalmycotoxinsmedicinecytotoxicityMedicineMycotoxinCytotoxicityZearalenoneToxins
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High Throughput Screening for Bioactive Volatile Compounds and Polyphenols from Almond (Prunus amygdalus) Gum: Assessment of Their Antioxidant and An…

2016

This work was devoted to recover and identify bioactive polyphenols and volatile compounds from almond gum, which can be used as food additives and/or nutraceuticals. For this purpose, solvent extract was obtained after hydrodistillation of almond gum and the extracted volatiles were identified using gas chromatography-mass spectrometry (GC-MS). The major compounds were 9-octadecenoic acid (18.47%), 3-eicosene (17.04%), hexadecanoic acid (13.82%), benzyl salycilate (9.54%), 1-octadecene (7.28%), cetene (4.38%) and turmerone (3.2%). Subsequently, the antioxidant and antibacterial activities of the obtained extracts rich in polyphenols and volatile compounds were evaluated. Antioxidant activi…

Antioxidantfood.ingredientDPPHGeneral Chemical Engineeringmedicine.medical_treatmentOrganoleptic01 natural scienceschemistry.chemical_compound0404 agricultural biotechnologyfoodNutraceuticalmedicineOrganic chemistryFood sciencebiologyChemistryFood additive010401 analytical chemistry04 agricultural and veterinary sciencesGeneral Chemistrybiology.organism_classificationAscorbic acid040401 food science0104 chemical sciencesPolyphenolMicrococcus luteusFood ScienceJournal of Food Processing and Preservation
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Anti-inflammatory activity of erycristagallin, a pterocarpene from Erythrina mildbraedii.

2003

Erycristagallin, a pterocarpene isolated from Erythrina mildbraedii, was tested in vitro for its antioxidant properties on the stable 2,2-diphenyl-1-pycryl-hydrazyl (DPPH) free radical and on the arachidonic acid metabolism. In addition, erycristagallin was tested on different experimental models of inflammation, such as the acute and chronic inflammation induced by the application of 12-O-tetradecanoylphorbol 13-acetate (TPA) on mice and the phospholipase A(2)-induced mouse paw oedema test. In the carrageenan-induced mouse paw oedema test, the ethyl acetate extract obtained from E. mildbraedii showed anti-inflammatory activity, and erycristagallin was isolated as the active principle. In v…

Antioxidantmedicine.drug_classDPPHmedicine.medical_treatmentAnti-Inflammatory AgentsInflammationPharmacologyCarrageenanHeterocyclic Compounds 4 or More RingsLeukotriene B4Anti-inflammatoryAntioxidantsPhospholipases Achemistry.chemical_compoundMicePicratesIn vivomedicineAnimalsEdemaRats WistarErythrinaPharmacologyPhospholipase AArachidonic AcidPlant ExtractsBiphenyl CompoundsEarFree Radical ScavengersIsoflavonesIn vitroHindlimbRatsBiphenyl compoundchemistryBiochemistryFemalemedicine.symptomEuropean journal of pharmacology
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