Search results for "Dracaena"

showing 9 items of 9 documents

Two new flavonoids from Dracaena usambarensis Engl.

2020

Abstract Investigations of the root extract of Dracaena usambarensis Engl. for anticancer principles led to the characterization of one new homoisoflavonoid, (3S)-3,4ʹ,5,6-tetrahydroxy-7-methoxyhomoisoflavanone (1) and a new retrodihydrochalcone, 4ʹ,4-dihydroxy-2,3-dimethoxydihydrochalcone (2) along with six previously reported compounds, including two homoisoflavonoids, 7-O-methyl-8-demethoxy-3-hydroxy-3,9-dihydropunctatin (3) and loureiriol (4); a phenolic amide, 3-(4ʹʹʹ-hydroxyphenyl)-N-[2ʹ-(4ʹʹ-hydroxyphenyl)-2ʹ-methoxyethyl]acrylamide (5); a spirostane, 25S-spirosta-1,4-dien-3-one (6) and two steroids, stigmasterol (7) and stigmasterol 3-O-β-D-glucopyranoside (8). The structures of 1-8…

Circular dichroismStigmasterolbiology010405 organic chemistryStereochemistryResazurinPlant ScienceDrug resistancebiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciences010404 medicinal & biomolecular chemistrychemistry.chemical_compoundchemistryAmideAcrylamideCytotoxicityAgronomy and Crop ScienceDracaenaBiotechnologyPhytochemistry Letters
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Homoisoflavonoids analysis in Dracaena draco fruits by HPLC-DAD-ESI-MS.

2008

Dracaena draco
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Steroidal saponins from Dracaena marginata

2013

Three new steroidal saponins and ten known ones were isolated from the bark of Dracaena marginata, along with two known steroidal saponins from the roots. Their structures were elucidated on the basis of extensive 1D and 2D NMR experiments and mass spectrometry as (25R)-26-(beta-D-glucopyranosyloxy)3beta,22alpha-dihydroxyfurost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-[alpha-L-rhamnopyranosyl-(1 --> 4)]-beta-D-glucopyranoside (1), (25R)-26-(beta-D-glucopyranosyloxy)-3beta,22alpha-dihydroxyfurost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-sulfo-alpha-L-arabinopyranoside (2), and (25S)-3beta-hydroxyspirost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-sulfo-alpha-L…

PharmacologyMagnetic Resonance SpectroscopyTraditional medicinebiologyChemistryDracaena marginataPlant ScienceGeneral MedicineNuclear magnetic resonance spectroscopySaponinsMass spectrometrybiology.organism_classificationMiceAsparagaceaeComplementary and alternative medicinevisual_artCell Line TumorDrug Discoveryvisual_art.visual_art_mediumAnimalsHumansBarkTwo-dimensional nuclear magnetic resonance spectroscopyDracaenaDracaena
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Spirostane-Type Saponins from Dracaena fragrans Yellow Coast

2015

Three steroidal glycosides were isolated from the bark of Dracaena fragrans (L.) Ker Gawl. « Yellow Coast », and a fourth from the roots and the leaves. Their structures were characterized on the basis of extensive 1D and 2D NMR experiments and mass spectrometry, and by comparison with NMR data of the literature. These saponins have the spirostane-type skeleton and are reported in this species for the first time.

PharmacologyTraditional medicineSteroidal glycosidesDracaena fragransPhytosterolsPlant ScienceGeneral MedicineSaponinsBiologybiology.organism_classificationComplementary and alternative medicinevisual_artDrug Discoveryvisual_art.visual_art_mediumBarkDracaena
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Cytotoxicity of Secondary Metabolites from Dracaena viridiflora Engl & Krause and their Semisynthetic Analogues

2017

The MeOH extract of Dracaena viridiflora was found to display significant cytotoxicity against some cancer cell lines. Systematic phytochemical investigation of this extract led to the isolation and structure elucidation of ten secondary metabolites including five spirostane (1-5) and one furostane (6) steroidal saponins. Furthermore, some acetylated spirostane analogues and three previously unreported derivatives with the 22,26-epoxycholesta-5,22-diene skeleton (15-17) were prepared from trillin (1), prosapogenin A of dioscin (2) and dioscin (4) by reaction with ZnCl 2/Ac 2O. Among the isolated and semisynthetic compounds, dioscin showed the most potent cytotoxicity against A549, Jurkat an…

Pharmacologysteroidal saponinsbiologyTraditional medicine010405 organic chemistryChemistryOrganic ChemistryPlant Sciencebiology.organism_classification01 natural sciencesDracaena viridifloralcsh:QK1-9890104 chemical scienceslcsh:Chemistrylcsh:QD241-441010404 medicinal & biomolecular chemistrylcsh:QD1-999lcsh:Organic chemistryepoxycholesta-5.22-dieneslcsh:BotanyDrug DiscoverycytotoxicityCytotoxicityDracaenaRecords of Natural Products
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Dracaena draco (Dracaenaceae) spontaneizzata a Palermo (Nord Sicilia)

2013

Dracaena draco (Dracaenaceae), naturalized in Palermo (N Sicily). – Dracaena draco L., an evergreen tree from the Atlantic islands (Canary, Cape verde and Madera Islands) introduced in Sicily in the second half of the XIX Century as an ornamental plant, was found naturalized on the Mount Pellegrino slopes (Palermo). This new Sicilian finding, confirms, more than 20 years after the first record in the East Cost of Sicily, the naturalization of the species in Italy.

Settore BIO/03 - Botanica Ambientale E Applicataornamental plants naturalization Dracaena
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Steroidal saponins from two species of Dracaena.

2010

Four new steroidal saponins (1-4) were isolated from the stem and bark of two species of Dracaena: deistelianosides A and B (1 and 2) from D. deisteliana and arboreasaponins A and B (3 and 4) from D. arborea. Six known saponins and one known sapogenin were also isolated. The structures of 1-4 were established as diosgenin 3-O-[3-O-sulfate-alpha-l-rhamnopyranosyl-(1-->4)]-beta-d-glucopyranoside (1), 1-O-beta-d-xylopyranosyl-(1-->2)-[alpha-l-rhamnopyranosyl-(1-->3)]-beta-d-fucopyranosyl(23S,24S)-spirosta-5,25(27)-diene-1beta,3beta,23alpha,24alpha-tetrol 24-O-alpha-l-arabinopyranoside (2), pennogenin-3-O-alpha-l-rhamnopyranosyl-(1-->2)-[alpha-l-rhamnopyranosyl-(1-->3)]-[6-O-acetyl]-beta-d-gluc…

StereochemistryChemical structureSaponinPharmaceutical ScienceSapogeninPharmacognosyAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryHumansCameroonNuclear Magnetic Resonance BiomolecularDracaenaPharmacologychemistry.chemical_classificationPlants MedicinalbiologyMolecular StructurePlant StemsChemistryOrganic ChemistryGlycosideStereoisomerismDiosgeninSaponinsbiology.organism_classificationHCT116 CellsComplementary and alternative medicinevisual_artvisual_art.visual_art_mediumPlant BarkMolecular MedicineBarkSteroidsDracaenaHT29 CellsJournal of natural products
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Phytochemical and anti-staphylococcal biofilm assessment of Dracaena draco L. Spp. draco resin

2013

Background: Dracaena draco L. ssp. draco is known as the “dragon's blood tree” and it is endemic from the Canary Islands and Morocco. Objective: Carry out phytochemical investigation of acetonic extracts of red resin obtained from the trunk of D. draco, to obtain to the isolation of the most abundant resin constituents, belonging to the class of flavonoids: flavans, along with homoisoflavans and homoisoflavanones. Materials and Methods: The structures of the isolated compounds were established by Nuclear Magnetic Resonance (NMR) and mass spectrometry data and comparison with literature data. The acetonic extract was evaluated for its anti-staphylococcal properties against two reference stra…

Traditional medicineDracaena draco L.Antibiofilm activity Dracaena draco L. dragon blood resin flavan homoisoflavanBiofilmPharmaceutical SciencehomoisoflavanBiologySettore BIO/19 - Microbiologia Generalebiology.organism_classificationSettore CHIM/08 - Chimica FarmaceuticaDraco (constellation)dragon blood resinchemistry.chemical_compoundPhytochemicalchemistryflavanFlavanAntibiofilm activityDrug DiscoveryBotanyDracaena dracoOriginal ArticlePharmacognosy Magazine
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Isolation and caracterisation of saponins from three plants of Araliaceae and Dracaenaceae families and evaluation of their cytotoxic activities on t…

2010

The interest of the substances from natural origin, potentially antitumor led us to interest in triterpenoid and steroidal saponins of plants from the African biodiversity belonging to the Araliaceae and Dracaenaceae families of plants. Indeed, of the former studies undertaken on some plants of these two families led to obtaining complex and original molecules having excellent cytotoxic, immuno-modulating, anti-inflammatory properties. Within sight of these results we undertook pharmaco-chemical investigations on Cussonia arborea (Araliaceae), Dracaena deisteliana, and Dracaena arborea (Dracaenaceae), medicinal plants usually used in african traditional pharmacopeia to treat various disease…

[SDV.SA] Life Sciences [q-bio]/Agricultural sciences[ SDV.BV ] Life Sciences [q-bio]/Vegetal Biology[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyCytotoxicityCussonia arboreaDracaena arboreaDracaena deistelianaTriterpenoid saponinsDracaenaceaeSaponines triterpéniquesSaponines stéroïdiquesCytotoxicité[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology[SDV.BV] Life Sciences [q-bio]/Vegetal BiologyAraliaceae[ SDV.SA ] Life Sciences [q-bio]/Agricultural sciencesSteroidal saponins
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