6533b86dfe1ef96bd12cac05
RESEARCH PRODUCT
Steroidal saponins from Dracaena marginata
David PertuitTomofumi MiyamotoPatrick DutartreAnne Claire Mitaine-offerMarie Aleth Lacaille-duboisChiaki TanakaStéphanie DelemasureAbdelmalek Rezguisubject
PharmacologyMagnetic Resonance SpectroscopyTraditional medicinebiologyChemistryDracaena marginataPlant ScienceGeneral MedicineNuclear magnetic resonance spectroscopySaponinsMass spectrometrybiology.organism_classificationMiceAsparagaceaeComplementary and alternative medicinevisual_artCell Line TumorDrug Discoveryvisual_art.visual_art_mediumAnimalsHumansBarkTwo-dimensional nuclear magnetic resonance spectroscopyDracaenaDracaenadescription
Three new steroidal saponins and ten known ones were isolated from the bark of Dracaena marginata, along with two known steroidal saponins from the roots. Their structures were elucidated on the basis of extensive 1D and 2D NMR experiments and mass spectrometry as (25R)-26-(beta-D-glucopyranosyloxy)3beta,22alpha-dihydroxyfurost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-[alpha-L-rhamnopyranosyl-(1 --> 4)]-beta-D-glucopyranoside (1), (25R)-26-(beta-D-glucopyranosyloxy)-3beta,22alpha-dihydroxyfurost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-sulfo-alpha-L-arabinopyranoside (2), and (25S)-3beta-hydroxyspirost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-sulfo-alpha-L-arabinopyranoside (3).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-02-01 |