Search results for "Drosophilia"
showing 5 items of 5 documents
Sex-specific responses to cold in a very cold-tolerant, northern Drosophila species
2021
Funding: This work was supported by Academy of Finland projects 268214 and 322980 to MK and a NERC (UK) grant NE/P000592/1 to MGR. Organisms can plastically alter resource allocation in response to changing environmental factors. For example, in harsh conditions, organisms are expected to shift investment from reproduction toward survival; however, the factors and mechanisms that govern the magnitude of such shifts are relatively poorly studied. Here we compared the impact of cold on males and females of the highly cold-tolerant species Drosophila montana at the phenotypic and transcriptomic levels. Although both sexes showed similar changes in cold tolerance and gene expression in response…
Neiromediatora serotonīna ietekme uz augļu mušu (Drosophila melanogaster) kustību lateralitāti
2022
Augļu mušu (Drosophila melanogaster) depresīvā uzvedības modeļa izpēte ar y-tipa labirinta metodi, var palīdzēt saprast depresīvās uzvedības pamatelementus. Augļu mušas ir labi pazīstams un plaši pielietojams modeļobjekts bioloģijas nozares pētījumos, ir zināms, ka serotonīna sintēzes cikls ir evolucionāri konservatīvs, līdzīgs visiem dzīvniekiem, tāpēc ir svarīgi apzināties kādus ķīmiskos līdzekļus vislabāk pielietot tālakos uzvedības pētījumos. Darba mērķis ir izpētīt vai selektīvie serotonīna inhibitori ietekmē augļu mušu Oregon R kustību lateritāti. Kopā pētījumā analizēti, selektīvā serototonīna atpakaļpiesaistes inhibitora escitaloprāma un, vielas ar antidepresīvām īpašībām, triptofān…
Inter- and intra-specific genomic divergence in Drosophila montana shows evidence for cold adaptation
2018
This work was supported by the Academy of Finland to AH (projects 132619 and 267244) and to MK (projects 268214 and 272927) and NERC (UK) funding to MGR (grants NE/E015255/1 and NE/J020818/1) and PhD studentship to DJP (NE/I528634/1). The genomes of species that are ecological specialists will likely contain signatures of genomic adaptation to their niche. However, distinguishing genes related to ecological specialism from other sources of selection and more random changes is a challenge. Here we describe the genome of Drosophila montana, which is the most extremely cold-adapted Drosophila species. We use branch tests to identify genes showing accelerated divergence in contrasts between col…
Drosophila Evolution over Space and Time (DEST) : A New Population Genomics Resource
2021
Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome datasets from natural populations of this species have been published over the last years. A major challenge is the integration of disparate datasets, often generated using different sequencing technologies and bioinformatic pipelines, which hampers our ability to address questions about the evolution of this species. Here we address these issues by developing a bioinformatics pipeline that maps pooled sequencing (Pool-Seq) reads from D. melanogaster to a hologenome consisting of fly and symbiont genomes and estimates allele frequencies using either a heuristic (PoolSNP) or a…
Inducing Cold-Sensitivity in the Frigophilic Fly Drosophila montana by RNAi
2016
The work was supported by CNPq (Fellowship to FMV) and a NERC Studentship to DJP. Cold acclimation is a critical physiological adaptation for coping with seasonal cold. By increasing their cold tolerance individuals can remain active for longer at the onset of winter and can recover more quickly from a cold shock. In insects, despite many physiological studies, little is known about the genetic basis of cold acclimation. Recently, transcriptomic analyses in Drosophila virilis and D.montana revealed candidate genes for cold acclimation by identifying genes upregulated during exposure to cold. Here, we test the role of myo-inositol-1-phosphate synthase (Inos), in cold tolerance in D. montana …