Search results for "Drug Prescription"

showing 10 items of 32 documents

Under-prescription of statins in patients with non-alcoholic fatty liver disease

2017

Abstract Background and Aim Non-alcoholic fatty liver disease (NAFLD) is a common disease associated with high cardiovascular risk. Management of dyslipidaemia plays a pivotal role in the prevention of CV events and statins have proved to be safe in these patients. However, in everyday clinical practice statin prescription is sometimes limited because of the concern of physicians about side-effects. The aim of the study was to investigate if the presence of NAFLD affects the prescription of lipid-lowering treatment in a large series of patients with cardio-metabolic disorders. Methods and Results Cardiovascular risk and LDL-C targets were defined according to ESC/EAS Guidelines in 605 conse…

MaleSettore MED/09 - Medicina InternaEndocrinology Diabetes and MetabolismMedicine (miscellaneous)Disease030204 cardiovascular system & hematologyEndocrinology0302 clinical medicineDrug PrescriptionNon-alcoholic Fatty Liver DiseaseRisk FactorsCardiovascular DiseaseNutrition and DieteticPractice Patterns Physicians'Nutrition and Dieteticsmedicine.diagnostic_testFatty liverMiddle AgedDiabetes and MetabolismCardiovascular DiseasesPractice Guidelines as TopicCohortUnder-prescriptionFemalelipids (amino acids peptides and proteins)030211 gastroenterology & hepatologyGuideline AdherenceCardiology and Cardiovascular MedicineHumanAdultCardiovascular risk; Non-alcoholic fatty liver disease; Statins; Under-prescription; Medicine (miscellaneous); Endocrinology Diabetes and Metabolism; Nutrition and Dietetics; Cardiology and Cardiovascular Medicinemedicine.medical_specialtyStatinmedicine.drug_classContext (language use)Health Services MisuseDrug Prescriptions03 medical and health sciencesInternal medicinemedicineHumansMedical prescriptionAgedDyslipidemiasCross-Sectional Studiebusiness.industryRisk FactorStatinsStatinnutritional and metabolic diseasesNon alcoholicBiomarkerCholesterol LDLCardiovascular riskmedicine.diseaseCross-Sectional StudiesDyslipidemiaPhysical therapyHydroxymethylglutaryl-CoA Reductase InhibitorHydroxymethylglutaryl-CoA Reductase InhibitorsLipid profilebusinessBiomarkersNutrition, Metabolism and Cardiovascular Diseases
researchProduct

Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study

2011

PURPOSES: We evaluated the prevalence and factors associated with polypharmacy and investigated the role of polypharmacy as a predictor of length of hospital stay and in-hospital mortality. METHODS: Thirty-eight internal medicine wards in Italy participated in the Registro Politerapie SIMI (REPOSI) study during 2008. One thousand three hundred and thirty-two in-patients aged ≥65 years were enrolled. Polypharmacy was defined as the concomitant use of five or more medications. Linear regression analyses were used to evaluate predictors of length of hospital stay and logistic regression models for predictors of in-hospital mortality. Age, sex, Charlson comorbidity index, polypharmacy, and numb…

MaleSettore MED/09 - Medicina InternaMultivariate analysis030204 cardiovascular system & hematologyLogistic regressionCohort Studies0302 clinical medicineElderlyPrevalenceMedicinePharmacology (medical)Hospital MortalityProspective Studies030212 general & internal medicinePractice Patterns Physicians'Prospective cohort studyComputingMilieux_MISCELLANEOUSAged 80 and overHospital stayGeneral MedicineSettore MED/45 - Scienze Infermieristiche Generali Cliniche E Pediatriche3. Good healthHospitalizationIn-hospital mortalityItalyFemalelength of hospital stayCohort studymedicine.medical_specialtyDrug PrescriptionsElderly Hospital stay In-hospital mortality PolypharmacyElderly Polypharmacy Hospital stay In-hospital mortality03 medical and health sciencesInternal medicineInternal MedicineHumansAdverse effectAgedPharmacologyPolypharmacybusiness.industryOdds ratioConfidence intervalLogistic ModelsLinear ModelsSettore BIO/14 - FarmacologiaPolypharmacybusinesselderly; hospital stay; in-hospital mortality; length of hospital stay; polypharmacy
researchProduct

Drug Prescription and Delirium in Older Inpatients: Results From the Nationwide Multicenter Italian Delirium Day 2015-2016

2019

Objective This study aimed to evaluate the association between polypharmacy and delirium, the association of specific drug categories with delirium, and the differences in drug-delirium association between medical and surgical units and according to dementia diagnosis. Methods Data were collected during 2 waves of Delirium Day, a multicenter delirium prevalence study including patients (aged 65 years or older) admitted to acute and long-term care wards in Italy (2015-2016); in this study, only patients enrolled in acute hospital wards were selected (n = 4,133). Delirium was assessed according to score on the 4 "A's" Test. Prescriptions were classified by main drug categories; polypharmacy w…

Malediagnosismedications0302 clinical medicinepreventionAged 80 and over; Delirium; Drug Prescriptions; Female; Hospital Departments; Humans; Male; Prevalence; Polypharmacy; Prescription Drugs80 and overPrevalenceMedicineLS4_4030212 general & internal medicineAcute hospitalmedia_commonAged 80 and overConfoundingelderly patients hip fracture hospitalized patients prediction rule risk factor dementia events medications prevention diagnosisrisk-factorrisk factorhip fracturePsychiatry and Mental HealthFemalemedicine.symptomeventsDrugmedicine.medical_specialtyPrescription Drugshospitalized-patientsmedia_common.quotation_subjectMEDLINEHospital DepartmentsSocio-culturaleelderly-patientselderly patientsbehavioral disciplines and activitiesDrug Prescriptions03 medical and health sciencesInternal medicinemental disordersDementiaHumansMedical prescriptionprediction ruleAgedPolypharmacybusiness.industryhospitalized patientsDeliriummedicine.diseasenervous system diseasesPolypharmacyDeliriumelderly-patients; hip fracture; hospitalized-patients; prediction rule; risk-factor; dementia; events; medications; prevention; diagnosisbusiness030217 neurology & neurosurgerydementia
researchProduct

Évaluation de la prescription des antalgiques de palier II chez la personne âgée de 75 ans en médecine générale

2017

Although step-2 analgesics (S2A) are recommended when step-1 analgesics (S1A) are ineffective or in cases of moderate to severe pain, their efficacy varies. This study evaluated the place attributed by general practitioners (GPs) to S2A in the treatment of nociceptive pain in elderly persons (EP). Descriptive, transversal and declarative study conducted among GPs in Burgundy. In total, 115 GPs took part in the survey. Among these, 60.8% had at least one consultation/day for pain. After paracetamol, which was systematically preferred, 56.4% prescribed S2A for EP. The reasons for prescribing S2A included pain not relieved by S1A in 93% of cases, another medical treatment or not (42.6%), or th…

Malemedicine.medical_specialtyConstipationNauseaAnalgesic[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyDrug Prescriptionspersonne âgéeAmbulatory careGeneral PractitionersmedicineHumansPain ManagementMedical prescriptionAdverse effectBiological PsychiatryAgedAged 80 and overAnalgesics[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologybusiness.industryChronic painmedicine.diseaseDrug Utilizationmédecine généraleNeuropsychology and Physiological PsychologyHealth Care Surveysantalgiques de palier IIVomitingPhysical therapyFemaleFranceNeurology (clinical)Chronic PainGeriatrics and Gerontologymedicine.symptombusinessGériatrie et Psychologie Neuropsychiatrie du Viellissement
researchProduct

The Prescription of Vitamin K Antagonists in a Very Old Population: A Cross-Sectional Study of 8696 Ambulatory Subjects Aged Over 85 Years

2020

We compared very elderly people taking vitamin K antagonists (VKA) and those not taking VKA (noVKA). Individuals were included in the noVKA group if there was no VKA on their reimbursed prescriptions during the study period. We also compared three subgroups, constituted by VKA type (fluindione, warfarin, or acenocoumarol). We included individuals aged over 85 years, affiliated to Mutualit&eacute

Malemedicine.medical_specialtyanticoagulantsVitamin KCross-sectional studyHealth Toxicology and MutagenesisPopulationlcsh:Medicine030204 cardiovascular system & hematologyArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinemedicineHumans030212 general & internal medicinePractice Patterns Physicians'Medical prescriptioneducationAgedAged 80 and overeducation.field_of_studyAcenocoumaroldrug prescriptionFluindionebusiness.industrylcsh:RPublic Health Environmental and Occupational HealthWarfarinaged 80 and overoutpatientsCross-Sectional StudiesPrescriptionschemistryAmbulatoryPlatelet aggregation inhibitorFemaleWarfarinbusinessmedicine.drugInternational Journal of Environmental Research and Public Health
researchProduct

Problematic discharge from hospital for patients prescribed opioids for cancer pain.

2005

Narcoticscancer patientmedicine.medical_specialtybusiness.industryPainDrug PrescriptionsPatient DischargePain ladderAnesthesiology and Pain MedicineText miningopioids for cancer paindischarge from hospitalNeoplasmsPhysical therapyMedicineHumansNeurology (clinical)businessCancer painGeneral NursingJournal of pain and symptom management
researchProduct

Antibiotic use and associated factors in a large sample of hospitalised older people

2019

Objectives: The aims of this study were to assess (i) the prevalence of antibiotic use, (ii) factors associated with their use and (iii) the association with in-hospital mortality in a large sample of hospitalised older people in Italy.Methods: Data were obtained from the 2010-2017 REPOSI register held in more than 100 internal medicine and geriatric wards in Italy. Patients aged >= 65 years with at least one antibiotic prescription during their hospitalisation were selected. Multivariable logistic regression models were used to determine factors associated with antibiotic use.Results: A total of 5442 older patients were included in the analysis, of whom 2786 (51.2%) were prescribed anti…

RegistrieMale0301 basic medicineAntibioticsLogistic regression0302 clinical medicineDrug Prescription80 and overPrevalenceImmunology and AllergyLS4_4Hospital MortalityRegistries030212 general & internal medicineMultivariate AnalysiRespiratory Tract InfectionsAged 80 and overAnti-Bacterial AgentsHospitalizationItalyAntibiotic useFemaleHumanMicrobiology (medical)medicine.medical_specialtyLogistic ModelInternal medicine wardmedicine.drug_class030106 microbiologyImmunologySocio-culturaleDrug PrescriptionsMicrobiologyOdds03 medical and health sciencesAntibiotic resistanceAnti-Bacterial AgentmedicineAntibiotic use; Internal medicine ward; Older people; Aged; Aged 80 and over; Anti-Bacterial Agents; Drug Prescriptions; Female; Geriatric Assessment; Hospital Mortality; Hospitalization; Humans; Italy; Logistic Models; Male; Multivariate Analysis; Prevalence; Registries; Respiratory Tract InfectionsHumansMedical prescriptionAntibiotic useGeriatric AssessmentAgedbusiness.industryConfidence intervalLogistic ModelsAntibiotic use Internal medicine ward Older peopleMultivariate AnalysisEmergency medicineOlder peopleOlder peoplebusinessAntibiotic use; Internal medicine ward; Older peopleJournal of Global Antimicrobial Resistance
researchProduct

The stigma of low opioid prescription in the hospitalized multimorbid elderly in Italy.

2015

The primary aim of this study was to evaluate the prevalence of opioid prescriptions in hospitalized geriatric patients. Other aims were to evaluate factors associated with opioid prescription, and whether or not there was consistency between the presence of pain and prescription. Opioid prescriptions were gathered from the REgistro POliterapie Societa` Italiana di Medicina Interna (REPOSI) data for the years 2008, 2010 and 2012. 1,380 in-patients, 65+ years old, were enrolled in the first registry run, 1,332 in the second and 1,340 in the third. The prevalence of opioid prescription was calculated at hospital admission and discharge. In the third run of the registry, the degree of pain was…

RegistrieMalePoison controlOlder personComorbidityPractice PatternsDrug PrescriptionOlder persons Pain Analgesic opioids80 and overRegistriesPractice Patterns Physicians'Pain MeasurementAged 80 and overAnalgesicsAnalgesic opioids; Older persons; Pain; Emergency Medicine; Internal MedicineAnalgesics OpioidHospitalizationItalyEmergency MedicineFemaleTramadolHumanmedicine.drugmedicine.medical_specialtyAttitude of Health PersonnelAnalgesicPainOpioidelderlyDrug PrescriptionsInjury preventionmedicineInternal MedicineHumansAnalgesic opioidsMedical prescriptionAgedPhysicians'business.industryCodeineSettore MED/09 - MEDICINA INTERNAAnalgesic opioidmedicine.diseaseComorbidityOlder persons Pain Analgesic opioidsOpioidOlder personsEmergency medicinebusinessAnalgesic opioids; Older persons; Pain; Aged; Aged 80 and over; Analgesics Opioid; Comorbidity; Drug Prescriptions; Female; Humans; Italy; Male; Pain; Pain Measurement; Practice Patterns Physicians'; Registries; Attitude of Health Personnel; Hospitalization; Internal Medicine; Emergency MedicineAnalgesic opioids; Older persons; Pain; Aged; Aged 80 and over; Analgesics Opioid; Comorbidity; Drug Prescriptions; Female; Humans; Italy; Male; Pain; Pain Measurement; Practice Patterns Physicians'; Registries; Attitude of Health Personnel; Hospitalization; Emergency Medicine; Internal Medicine
researchProduct

Pattern of in-hospital changes in drug use in the older people from 2010 to 2016

2017

Purpose: To assess the pattern of in-hospital changes in drug use in older patients from 2010 to 2016. Methods: People aged 65 years or more acutely hospitalized in those internal medicine and geriatric wards that did continuously participate to the REgistro POliterapie Società Italiana di Medicina Interna register from 2010 to 2016 were selected. Drugs use were categorized as 0 to 1 drug (very low drug use), 2 to 4 drugs (low drug use), 5 to 9 drugs (polypharmacy), and 10 or more drugs (excessive polypharmacy). To assess whether or not prevalence of patients in relation to drug use distribution changed overtime, adjusted prevalence ratios (PRs) was estimated with log-binomial regression mo…

RegistrieMalepharmacoepidemiologyEpidemiologyDischarged alive030204 cardiovascular system & hematologyinternal medicine and geriatric warddrug use; excessive polypharmacy; internal medicine and geriatric wards; older people; pharmacoepidemiology; polypharmacyexcessive polypharmacyolder people0302 clinical medicineDrug PrescriptionRisk Factors80 and overPharmacology (medical)030212 general & internal medicineRegistriesAt-Risk Populationmedia_commonAged 80 and overOvertimedrug use excessive polypharmacy internal medicine and geriatric wards older people pharmacoepidemiology polypharmacyinternal medicine and geriatric wardsPharmacoepidemiologyHospitalizationItalyFemaleMedical emergencyHumanDrugmedicine.medical_specialtymedia_common.quotation_subjectSocio-culturaleDrug Prescriptions03 medical and health sciencesHospital dischargemedicineInternal MedicineHumanspolypharmacyAgeddrug usePolypharmacyInpatientsbusiness.industryRisk Factormedicine.diseasedrug use; excessive polypharmacy; internal medicine and geriatric wards; older people; pharmacoepidemiology; polypharmacy; Aged; Aged 80 and over; Drug Prescriptions; Female; Hospitalization; Humans; Internal Medicine; Italy; Male; Polypharmacy; Registries; Risk Factors; InpatientsEmergency medicinePolypharmacyOlder peoplebusiness
researchProduct

Monitoring the quality of the hospital pharmacoterapeutic process by sentinel patient program

2018

To analyze the results of sentinel patient program to monitoring the  quality pharmacoterapeutic process in the hospitalized patient through  medication errors.Design: Observational, prospective and transversal study. Ambit: General hospital of 1,000 beds.From May 2011 to June 2016.  Sample: Patients with treatment prescribe within 24 hours of being admitted  with 4 or more medications.Medication error, drugs prescribed,  medications and doses dispensing, drugs administered. Safety indicators were  defined based on medication errors at each stage of the pharmacotherapeutic  process.Of the 746 patients studied, 334 had at least 1 medication error  (44.8%; IC95%: 41.7-47.8). In the 746 treatm…

lcsh:Rlcsh:Medicinelcsh:RS1-441Safety;Drug PrescriptionsQuality ImprovementDrug Hypersensitivitylcsh:Pharmacy and materia medicaMedication errorsQuality monitoringHumansPatient SafetyProspective StudiesSafetyPharmacy Service HospitalQuality of Health CareFarmacia Hospitalaria
researchProduct