Search results for "Dual"

Estar al otro lado de la mesa. Profesionales de los servicios públicos de empleo ante los dilemas de la activación laboral

2019

Under the paradigm of activation, the Public Employment Services has been reshaped by two levels of contractualization. On one hand, the collaboration of the administration with a network of agents on the programme scheme that make up the active policies of employment. On the other hand, the unemployed person?s access to a compartmentalized offer of services and individually taking responsibility for finding work. This double contractualization reveals redefinition of lowering public responsibility faced with the problem of unemployment that this activation supposes. This paper analyses how this redesign has an impact on how professionals serve the unemployed population. This lays bare, in …

Combined Spectroscopic and TD-DFT Analysis to Elucidate Substituent and Acidochromic Effects in Organic Dyes: A Case Study on Amino- versus Nitro-Sub…

2020

Made available in DSpace on 2020-12-12T01:33:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 A combined spectroscopic and TD-DFT case study was performed, to identify a robust method to calculate the complex near UV/Vis absorption spectra of various amino- vs. nitro-substituted 2,4-diphenylquinolines, which vary strongly under neutral and successively acidic conditions. For this, different DFT functionals were tested for geometry optimization and the TD part to calculate the neutral and different protonated species in a fast screening approach, i. e. using single point calculations in an implicit solvent. Offset-corrected M06HF, hitherto only applied to polymers, was identif…

Aplidin® induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 ph…

2006

Aplidin® is an antitumor agent in phase II clinical trials that induces apoptosis through the sustained activation of Jun N-terminal kinase (JNK). We report that Aplidin® alters glutathione homeostasis increasing the ratio of oxidized to reduced forms (GSSG/GSH). Aplidin® generates reactive oxygen species and disrupts the mitochondrial membrane potential. Exogenous GSH inhibits these effects and also JNK activation and cell death. We found two mechanisms by which Aplidin® activates JNK: rapid activation of Rac1 small GTPase and downregulation of MKP-1 phosphatase. Rac1 activation was diminished by GSH and enhanced by L-buthionine (SR)-sulfoximine, which inhibits GSH synthesis. Downregulatio…

Heart Rate Variability Monitoring During Strength and High-Intensity Interval Training Overload Microcycles

2019

Objective: In two independent study arms, we determine the effects of strength training (ST) and high-intensity interval training (HIIT) overload on cardiac autonomic modulation by measuring heart rate (HR) and vagal heart rate variability (HRV).Methods: In the study, 37 well-trained athletes (ST: 7 female, 12 male; HIIT: 9 female, 9 male) were subjected to orthostatic tests (HR and HRV recordings) each day during a 4-day baseline period, a 6-day overload microcycle, and a 4-day recovery period. Discipline-specific performance was assessed before and 1 and 4 days after training.Results: Following ST overload, supine HR, and vagal HRV (Ln RMSSD) were clearly increased and decreased (small ef…

Filtración directa por membranas para potenciar la recuperación de recursos de las aguas residuales

2023

La filtración directa mediante membranas (FDM) es una atractiva alternativa para potenciar la recuperación de recursos en el ámbito del tratamiento de aguas residuales municipales (ARM). El objetivo de esta tecnología es mejorar la recuperación del material particulado afluente de las ARM mediante la implementación de una unidad de filtración por membrana como paso previo al tratamiento biológico secundario, reduciendo así las necesidades energéticas asociadas a la oxidación aeróbica de la materia orgánica en los sistemas de fangos activos. Asimismo, el fango concentrado en el tanque de membranas puede emplearse para incrementar la producción de metano durante el proceso de digestión anaero…

Comment positionner l'offre culturelle ? De la compréhension de la relation personne – objet à l'intégration du lieu de consommation

2005

This article seeks to answer the strategic question of the cultural institutions positioning by insisting on the need, on the one hand, for analyzing the total relation between the consumer and the cultural object (central road of positioning definition) and, on the other hand, for considering the role of the cultural place (peripheral road). We will be able to consider that the ways of differentiation are multiple and correspond to a conceptualization of the ambivalent cultural experience.

Selecting the special or choosing the common? A high-powered conceptual replication of Kim and Markus’ (1999) pen study

2022

Kim and Markus (1999) found that 74% of Americans selected a pen with an uncommon (vs. common) color, whereas only 24% of Asians made such a choice, highlighting a pronounced crosscultural difference in the extent to which people opt for originality or make majority-based choices. The present high-powered study (N = 729) conceptually replicates the results from Kim and Markus (1999; Study 3). However, our obtained effect size (r = .12) is significantly weaker than that of the original study (r = .52). Interestingly, given the globalization of mass media and the rapid economic progress of many Asian cultures during the last decades, a larger proportion of Chinese, but not American, participa…

Residual a posteriori error estimation for frictional contact with Nitsche method

2023

We consider frictional contact problems in small strain elasticity discretized with finite elements and Nitsche method. Both bilateral and unilateral contact problems are taken into account, as well as both Tresca and Coulomb models for the friction. We derive residual a posteriori error estimates for each friction model, following [Chouly et al, IMA J. Numer. Anal. (38) 2018, pp. 921-954]. For the incomplete variant of Nitsche, we prove an upper bound for the dual norm of the residual, for Tresca and Coulomb friction, without any extra regularity and without a saturation assumption. Numerical experiments allow to assess the accuracy of the estimates and their interest for adaptive meshing …

Il saggio di capitalizzazione della terra e dei miglioramenti fondiari

2008

Mapping of Biomass Residues for Potential Energy Generation from the Wine-Growing Sector in the Provinces of Palermo and Trapani

2019

This paper is based on results obtained during the project Vienergy (Interreg Italia-Malta programme 2007-2013) and contains data on the potential energy generation of biomass residues following pruning from vineyards located within the provinces of Trapani and Palermo. Analysis of the energy potential, following microgasification tests and heat production related to the biomass, included a preliminary mapping of vineyards in the area and an assessment of the total biomass available. Vineyard mapping was carried out using remote-sensing technologies: images were acquired and analysed using Landsat satellite; spectroradiometric calibration then took place using various targets obtained from …