Search results for "E isomer"
showing 10 items of 41 documents
Identification of metabolic enzymes in renal cell carcinoma utilizing PROTEOMEX analyses
2003
Abstract PROTEOMEX, an approach which combines conventional proteome analysis with serological screening, is a powerful tool to separate proteins and identify immunogenic components in malignant diseases. By applying this approach, we characterized nine metabolic enzymes which were differentially expressed in renal cell carcinoma (RCC) cell lines and compared their expression profiles to that of normal kidney epithelium cells. Four of these proteins, superoxide dismutase (SODC), triosephosphatase isomerase (TPIS), thioredoxin (THIO) and ubiquitin carboxyl-terminal hydrolase (UBL1) were further analysed for both their constitutive and interferon (IFN)-γ inducible protein expression pattern i…
Pressure-tuning of magnetism and linkage isomerism in iron(II) hexacyanochromate.
2005
A pressure-induced linkage isomerization of the cyanide anion has been observed in single crystals of a chromium(III)-iron(II) Prussian blue analogue of formula K0.4Fe4[Cr(CN)6]2.8 square1.2.16H2O (1). Upon application of pressure in the 0-1200 MPa range, the cyanide ligand rotates and becomes C-bonded to the iron(II) cations, leading to a stabilization of their diamagnetic low-spin states. The result is a decrease of magnetization and magnetic ordering temperatures from TC = 19 K at ambient pressure to 13 K at 1200 MPa. The initial magnetic properties can be restored on pressure release. The reversible movement of cyanide in the solid state can be exploited as a switch of the magnetic inte…
Studio teorico della reazione di idroisomerizzazione del cis-butene su cluster di palladio supportato
2008
Linkage isomerism in the metal complex hexa(thiocyanato)rhenate(IV): Synthesis and crystal structure of (NBu4)2[Re(NCS)6] and [Zn(NO3)(Me2phen)2]2[Re…
2008
Abstract The linkage isomers [Re(NCS)6]2− and [Re(NCS)5(SCN)]2− are obtained by the reaction of [ReBr6]2− with NCS− in dimethylformamide. Some differences in the chemical behavior allowed their separation and structural characterization in the form of (NBu4)2[Re(NCS)6] (1) and [Zn(NO3)(Me2phen)2]2[Re(NCS)5(SCN)] (2), respectively (Bu = n-C4H9 and Me2phen = 2,9-dimethyl-1,10-phenanthroline).
Thermodynamic and Kinetic Modeling of Co-utilization of Glucose and Xylose for 2,3-BDO Production by Zymomonas mobilis
2021
Prior engineering of the ethanologen Zymomonas mobilis has enabled it to metabolize xylose and to produce 2,3-butanediol (2,3-BDO) as a dominant fermentation product. When co-fermenting with xylose, glucose is preferentially utilized, even though xylose metabolism generates ATP more efficiently during 2,3-BDO production on a BDO-mol basis. To gain a deeper understanding of Z. mobilis metabolism, we first estimated the kinetic parameters of the glucose facilitator protein of Z. mobilis by fitting a kinetic uptake model, which shows that the maximum transport capacity of glucose is seven times higher than that of xylose, and glucose is six times more affinitive to the transporter than xylose.…
High resolution crystal structures of triosephosphate isomerase complexed with its suicide inhibitors: The conformational flexibility of the catalyti…
2011
The key residue of the active site of triosephosphate isomerase (TIM) is the catalytic glutamate, which is proposed to be important (i) as a catalytic base, for initiating the reaction, as well as (ii) for the subsequent proton shuttling steps. The structural properties of this glutamate in the liganded complex have been investigated by studying the high resolution crystal structures of typanosomal TIM, complexed with three suicide inhibitors: (S)-glycidol phosphate ((S)-GOP, at 0.99 A resolution), (R)-glycidol phosphate, ((R)-GOP, at 1.08 A resolution), and bromohydroxyacetone phosphate (BHAP, at 1.97 A resolution). The structures show that in the (S)-GOP active site this catalytic glutama…
Selective isomerization of a trans -butanediacetal derivative of tartaric acid with differentiating substituents at C-2 and C-3
2017
Abstract A trans-disubstituted butanediacetal derivative with two different substituents (ester and thioester) – methyl (2R,3R,5R,6R)-3-ethylsulfanylcarbonyl-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2-carboxylate, was selectively converted to the cis derivative – methyl (2S,3R,5R,6R)-3-ethylsulfanylcarbonyl-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2-carboxylate in high yield on a multigram scale. The product of this reaction offers the possibility for selective modification of one of the substituents, which was demonstrated by Fukuyama reduction of the thioester group.
Properties and interactions – melting point of tribromobenzene isomers
2021
The melting points of tribromobenzene isomers are correlated with the number, nature and distribution of intermolecular interactions in their structures.
Gold(iii) tetraarylporphyrin amino acid derivatives: ligand or metal centred redox chemistry?
2015
EPR spectroscopy and DFT calculations show that the site of reduction of porphyrinato gold(iii) complexes depends on the counterions X, the meso substituents R and the solvent.
The chemical composition of essential oil from Seseli tortuosum subsp. tortuosum and S. tortuosum subsp. maritimum (Apiaceae) aerial parts growing in…
2022
Seseli L. genus, belonging to the Apiaceae family, includes more than eighty taxa, mainly growing in Europe and Asia. Due to the several biological properties, species of this genus have been largely investigated, showing to be a rich source of coumarins, as well as, of essential oils with anti-inflammatory, antiviral, antifungal, cytotoxic, etc. properties. In the present study, the chemical composition of the essential oils from aerial parts of Sicilian accessions of Seseli tortuosum subsp. tortuosum and S. tortuosum subsp. maritimum were analysed by GC-MS. No one report has been previously published on the subsp. maritimum. The results showed the presence, in both oils, of large quantity…