Search results for "ECoG"

showing 10 items of 3774 documents

Changes in power curve shapes as an indicator of fatigue during dynamic contractions.

2010

The purpose of this study was to analyze exercise-induced leg fatigue during a dynamic fatiguing task by examining the shapes of power vs. time curves through the combined use of several statistical methods: B-spline smoothing, functional principal components and (supervised and unsupervised) classification. In addition, granulometric size distributions were also computed to allow for comparison of curves coming from different subjects. Twelve physically active men participated in one acute heavy-resistance exercise protocol which consisted of five sets of 10 repetition maximum leg press with 120 s of rest between sets. To obtain a smooth and accurate representation of the data, a basis of …

AdultMaleMultivariate statisticsBiomedical EngineeringBiophysicsKinematicsPower lawModels BiologicalStatisticsHumansOrthopedics and Sports MedicineComputer SimulationMuscle SkeletalMathematicsLegbusiness.industryRehabilitationFunctional data analysisContrast (statistics)Pattern recognitionPrincipal component analysisMuscle FatiguePhysical EnduranceArtificial intelligencebusinessSmoothingCurse of dimensionalityMuscle ContractionJournal of biomechanics
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Olfactory categorization: a developmental study.

2012

International audience; This study examined the ability of children to classify fruit and flower odors. We asked four groups of children (4-11 years of age) and a group of adults to identify, categorize, and evaluate the edibility, liking, and typicality of 12 fruit and flower odors. Results showed an increase in interindividual agreement with age for the taxonomic (fruit/flower) and function-based (edible/nonedible) categories but not for the hedonic component. So, it seems that this hedonic component is not the explicit basis for this increase in interindividual agreement when categorizing an odor as a fruit/flower odor or as being edible or nonedible. An age-related trend was also observ…

AdultMaleOlfactory perceptionOlfactory categorizationEstheticsLavenderConcept FormationHuman Development[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionExperimental and Cognitive PsychologyFlowers050105 experimental psychologyDevelopmental psychologyToxicologyDevelopmental and Educational PsychologyHumans0501 psychology and cognitive sciencesChildAgedAge differences05 social sciencesfood and beveragesRecognition PsychologyMiddle AgedClassificationOlfactory PerceptionCategorizationOdorChild PreschoolFruitLinear ModelsFemaleFrancePlants EdiblePsychology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition050104 developmental & child psychology
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Avelumab versus standard second line treatment chemotherapy in metastatic colorectal cancer patients with microsatellite instability: The SAMCO-PRODI…

2021

Abstract Immune checkpoint inhibitors have failed in treating metastatic colorectal cancer (mCRC) patients except those with dMMR/MSI tumors. However, until very recently we had only non-comparative promising data in this population with anti-programmed cell death 1/ programmed cell death ligand 1 (PD1/PD-L1) antibodies alone or combined with anti- cytotoxic T-lymphocyte-associated protein 4 (CTLA4) antibodies. This comparative phase II trial (NCT 03186326), conducted in more than 100 centers in France, will include dMMR/MSI mCRC patients with progression after a first-line treatment with chemotherapy ± targeted therapies, to evaluate efficacy and safety of the anti-PDL1 Avelumab versus a s…

AdultMaleOncologymedicine.medical_specialtyColorectal cancermedicine.medical_treatmentPopulationECOG Performance StatusAntibodies Monoclonal HumanizedAvelumab03 medical and health sciencesAntineoplastic Agents ImmunologicalClinical Trials Phase II as Topic0302 clinical medicineInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansMulticenter Studies as TopiceducationRandomized Controlled Trials as TopicChemotherapyeducation.field_of_studyHepatologybusiness.industryGastroenterologyMicrosatellite instabilityImmunotherapymedicine.diseaseProgression-Free SurvivalRegimen030220 oncology & carcinogenesisFemaleMicrosatellite Instability030211 gastroenterology & hepatologyFranceColorectal Neoplasmsbusinessmedicine.drugDigestive and Liver Disease
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MRI pattern recognition in multiple sclerosis normal-appearing brain areas

2011

ObjectiveHere, we use pattern-classification to investigate diagnostic information for multiple sclerosis (MS; relapsing-remitting type) in lesioned areas, areas of normal-appearing grey matter (NAGM), and normal-appearing white matter (NAWM) as measured by standard MR techniques.MethodsA lesion mapping was carried out by an experienced neurologist for Turbo Inversion Recovery Magnitude (TIRM) images of individual subjects. Combining this mapping with templates from a neuroanatomic atlas, the TIRM images were segmented into three areas of homogenous tissue types (Lesions, NAGM, and NAWM) after spatial standardization. For each area, a linear Support Vector Machine algorithm was used in mult…

AdultMalePathologymedicine.medical_specialtyMultiple SclerosisScienceNeuroimagingBiostatisticsGrey matterBiologycomputer.software_genreBrain mappingPattern Recognition Automated030218 nuclear medicine & medical imagingWhite matter03 medical and health sciences0302 clinical medicineText miningNeuroimagingVoxelImage Interpretation Computer-AssistedmedicineHumansMultidisciplinarymedicine.diagnostic_testbusiness.industryMultiple sclerosisStatisticsQRBrainMagnetic resonance imagingmedicine.diseaseDemyelinating DisordersMagnetic Resonance Imagingmedicine.anatomical_structureNeurologyCase-Control StudiesMedicineFemalebusinesscomputerCartographyMathematics030217 neurology & neurosurgeryResearch Article
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A validation study of an Italian version of the ID Migraine: preliminary results

2005

Migraine is a highly prevalent and disabling disease that is substantially undiagnosed in primary care. Recently, the ID Migraine, a self–administered questionnaire, was shown to be a valid and reliable screener for migraine in primary care in the USA. To validate an Italian version of the ID Migraine, we planned a multicentric study, evaluating at least 220 patients affected by various form of headache. The responses to the questionnaire were compared with the diagnosis of headache made by a headache specialist blind to the result of the questionnaire. Sensitivity, specificity, and positive and negative predictive values for migraine were calculated. The statistical analysis on 140 patient…

AdultMalePediatricsmedicine.medical_specialtyNeurologyMigraine DisordersMEDLINEClinical NeurologyDiseaseSensitivity and SpecificityHeadache centersIchd—II: Evaluation and ProposalsPredictive Value of TestsSurveys and QuestionnairesPositive predicative valuemedicineHumansMass ScreeningMigraineMigraine recognitionMass screeningLanguageID migraineId migrainePrimary Health Carebusiness.industryReproducibility of ResultsGeneral MedicineMiddle AgedPrimary caremedicine.diseaseItalian ID migraineAnesthesiology and Pain MedicineItalyMigrainePredictive value of testsFemaleNeurology (clinical)businessThe Journal of Headache and Pain
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Brain response to masked and unmasked facial emotions as a function of implicit and explicit personality self-concept of extraversion.

2016

Extraversion-introversion is a personality dimension referring to individual differences in social behavior. In the past, neurobiological research on extraversion was almost entirely based upon questionnaires which inform about the explicit self-concept. Today, indirect measures are available that tap into the implicit self-concept of extraversion which is assumed to result from automatic processing functions. In our study, brain activation while viewing facial expression of affiliation relevant (i.e., happiness, and disgust) and irrelevant (i.e., fear) emotions was examined as a function of the implicit and explicit self-concept of extraversion and processing mode (automatic vs. controlled…

AdultMalePersonality TestsPsychometricsmedia_common.quotation_subjectEmotionsNeuropsychological TestsBrain mapping050105 experimental psychologyDevelopmental psychologyExtraversion Psychological03 medical and health sciences0302 clinical medicinemedicinePersonalityHumans0501 psychology and cognitive sciencesmedia_commonFacial expressionBrain MappingExtraversion and introversionmedicine.diagnostic_testGeneral Neuroscience05 social sciencesImplicit-association testBrainMagnetic Resonance ImagingDisgustSelf ConceptExtraversion (Psychology)FemalePsychologyFunctional magnetic resonance imagingFacial Recognition030217 neurology & neurosurgeryCognitive psychologyNeuroscience
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Measuring Task-Switching Ability in the Implicit Association Test

2005

Abstract. Recently, the role of method-specific variance in the Implicit Association Test (IAT) was examined ( McFarland & Crouch, 2002 ; Mierke & Klauer, 2003 ). This article presents a new content-unspecific control task for the assessment of task-switching ability within the IAT methodology. Study 1 showed that this task exhibited good internal consistency and stability. Studies 2-4 examined method-specific variance in the IAT and showed that the control task is significantly associated with conventionally scored IAT effects of the IAT-Anxiety. Using the D measures proposed by Greenwald, Nosek, and Banaji (2003 ), the amount of method-specific variance in the IAT-Anxiety could b…

AdultMalePersonality TestsTask switchingAdolescentPsychometricsPsychometricsConcept FormationExperimental and Cognitive PsychologyTask (project management)Discrimination LearningArts and Humanities (miscellaneous)Internal consistencyReaction TimeHumansAttentionDiscrimination learningSet (psychology)General PsychologyAssociation LearningReproducibility of ResultsImplicit-association testGeneral MedicineVariance (accounting)Pattern Recognition VisualSet PsychologyFemalePsychologySocial psychologyAlgorithmsExperimental Psychology
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Quantifying changes in EEG complexity induced by photic stimulation.

2009

Summary Objectives: This study aims to characterize EEG complexity, measured as the prediction error resulting from nonlinear prediction, in healthy humans during photic stimulation. Methods: EEGs were recorded from 15 subjects with eyes closed (EC) and eyes open (EO), during the baseline condition and during stroboscopic photic stimulation (PS) at 5, 10, and 15 Hz. The mean squared prediction error (MSPE) resulting from nearest neighbor local linear prediction was taken as complexity index. Complexity maps were generated interpolating the MSPE index over a schematic scalp representation. Results: Statistical analysis revealed that: i) EEG shows good predictability in all conditions and see…

AdultMalePhotic StimulationComputer scienceHealth InformaticsElectroencephalographyMachine learningcomputer.software_genreBrain mappingComplexity indexHealth Information ManagementReference ValuesmedicineHumansEEGPredictabilityPredictability mapVisual stimulationHealth InformaticAdvanced and Specialized NursingBrain Mappingmedicine.diagnostic_testbusiness.industryStochastic processLocal linear predictionPattern recognitionElectroencephalographySignal Processing Computer-AssistedNeurophysiologymedicine.anatomical_structureNonlinear DynamicsScalpSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaFemaleArtificial intelligencebusinesscomputerAlgorithmsPhotic StimulationMethods of information in medicine
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Selection of odorants for memory tests on the basis of familiarity, perceived complexity, pleasantness, similarity and identification

2002

In a procedure for the selection of two equivalent sets of familiar and two equivalent sets of unfamiliar odours for use in odour memory studies, 24 naive subjects were first asked to rate the familiarity, perceived complexity and pleasantness of 54 a priori unfamiliar odours and 57 a priori familiar odours and to identify the latter. After selection of the 40 most familiar and the 40 least familiar odours, the subjects sorted each of these two sets into groups of similar odours. Their results were analysed by multidimensional scaling and cluster analysis and each set was divided into two recognition sets that had the same degree of similarity between target and distractor odours and that h…

AdultMalePhysiologymedia_common.quotation_subject050105 experimental psychology03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineCognitionMemoryPhysiology (medical)PerceptionSimilarity (psychology)Selection (linguistics)Humans0501 psychology and cognitive sciencesMultidimensional scalingSet (psychology)Equivalence (measure theory)ComputingMilieux_MISCELLANEOUSmedia_commonRecognition memoryAgedCommunicationbusiness.industryMemoria05 social sciencesMiddle AgedSensory SystemsSmell[CHIM.OTHE] Chemical Sciences/OtherMental RecallOdorantsFemalebusinessPsychology[CHIM.OTHE]Chemical Sciences/Other030217 neurology & neurosurgeryCognitive psychology
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Facial emotion space in schizophrenia

2007

Introduction. Previous studies show that patients with schizophrenia have a deficit in facial emotion recognition. In the framework of emotion categorisation theories, the purpose of the present study was to test if this impairment could result from abnormal boundaries between emotions (whether these boundaries are shifted along continuums or are less sharpened). Method. Twenty-six schizophrenic patients and the same number of healthy participants were required to perform a facial emotion recognition task and an emotion categorisation task with different emotion intensities obtained using morphing techniques. Results. The main results indicate that schizophrenic patients exhibited an emotio…

AdultMalePsychosisCognitive NeuroscienceSchizophrenia (object-oriented programming)media_common.quotation_subjectSpace (commercial competition)Severity of Illness IndexDelusionsDevelopmental psychologySocial cognitionPerceptionmedicineHumansCategorical variablemedia_commonFacial expressionRecognition Psychologymedicine.diseaseFacial ExpressionAffectPsychiatry and Mental healthCategorizationSchizophreniaFemalePsychologyCognitive psychologyCognitive Neuropsychiatry
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