Search results for "EFE"
showing 10 items of 5785 documents
Neuroinflammatory and behavioral susceptibility profile of mice exposed to social stress towards cocaine effects.
2021
Using the social defeat (SD) model, numerous studies have shown that stressed mice display an enhanced response to the motivational effects of cocaine in the self-administration (SA) and conditioned-place preference (CPP) paradigms. However, not all subjects exposed to stress express its harmful effects. Some are particularly susceptible to the deleterious effects of repeated SD, while resilient mice successfully cope with stressful experiences and display adjusted psychological functioning after stress. Vulnerability to develop stress-related disorders, such as depression, has been linked to coping strategies and more recently to individual differences in the immune system. However, no stu…
Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms
2019
Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors describe the scarce preclinical and human research about the actions of CBD on the effects of stimulant drugs, mainly cocaine and methamphetamine (METH). Additionally, the possible mechanisms underlying the therapeutic potential of CBD on stimulant use disorders are reviewed. CBD has reversed toxicity and seizures induced by cocaine, behavioural sensitization induced by amphetamines, motivation to self-administer cocaine and METH, context- …
Menopauzes simptomu mazināšanas iespējas un tās efektivitāte
2019
Ievads: sasniedzot jaunus medicīnas attīstības lēcienus, cilvēka vidējais dzīves ilgums ir pagarinājies kā vēl nekad. Mūsdienās sievietes pat neapsver iespēju, ka 50 gadu vecums būtu “dzīves beigas”, pēc literatūras datiem – katra otrā sieviete dzīvos vēl vismaz 30 gadus pēc pusmūža vecuma sasniegšanas. Menopauze ir pašlimitējošs fizioloģiskas novecošanas stāvoklis, bet tās radītie simptomi var ļoti ietekmēt sievietes dzīves kvalitāti. Informētība un piemērotas terapijas izvēle var ne tikai uzlabot sievietes pašsajūtu, bet arī atgriest iepriekšējo dzīves kvalitāti. Mērķis: analizēt menopauzes simptomu mazināšanas terapijas iespējas un to efektivitāti. Materiāli un metodes: tika veikts retro…
Toppdommerrollen i fotball : sammenhengen mellom angst og mental tøffhet og toppdommeres subjektive opplevelse av press i norsk fotball
2016
Masteroppgave i idrettsvitenskap - Universitetet i Agder 2016 Mental toughness, anxiety and pressure are well-used terms within sports, even though it can be difficult to understand the meaning of them. The purpose of this study was to examine the relationship between anxiety (cognitive- and somatic anxiety and self-confidence) and mental toughness, and top-class referees’ subjective experience on pressure as a soccer official. 183 top-class referees answered an online questionnaire. Mental toughness was measured by using the SMTQ and anxiety by using the CSAI-2. Of all the referees included in this study, 97.2% had been active footballers themselves, 44.3% had played on a high level. There…
Scholarly publishing depends on peer reviewers
2018
The peer-review crisis is posing a risk to the scholarly peer-reviewed journal system. Journals have to ask many potential peer reviewers to obtain a minimum acceptable number of peers accepting reviewing a manuscript. Several solutions have been suggested to overcome this shortage. From reimbursing for the job, to eliminating pre-publication reviews, one cannot predict which is more dangerous for the future of scholarly publishing. And, why not acknowledging their contribution to the final version of the article published? PubMed created two categories of contributors: authors [AU] and collaborators [IR]. Why not a third category for the peer-reviewer? published
Sorption of V and VI group metalloids (As, Sb, Te) on modified peat sorbents
2016
AbstractThe present work investigates arsenic, antimony and tellurium sorption using iron modified peat. The results were obtained using batch tests and the sorption was studied as a function of initial metalloid concentration, pH and sorption time, as well as the presence of competing substances. The obtained results indicate that modification of peat with Fe compounds significantly enhances the sorption capacity of the sorbents used for sorption of arsenic, antimony and tellurium. The optimal pH interval for the sorption of Sb(III) is 6.5–9 and for As(V) and Sb(V) – 3–6, while As(III) and tellurium sorption using Fe-modified peat is favourable in a wider interval of 3–9. The presence of c…
A Multiple Surrogate Assisted Decomposition Based Evolutionary Algorithm for Expensive Multi/Many-Objective Optimization
2019
Many-objective optimization problems (MaOPs) contain four or more conflicting objectives to be optimized. A number of efficient decomposition-based evolutionary algorithms have been developed in the recent years to solve them. However, computationally expensive MaOPs have been scarcely investigated. Typically, surrogate-assisted methods have been used in the literature to tackle computationally expensive problems, but such studies have largely focused on problems with 1–3 objectives. In this paper, we present an approach called hybrid surrogate-assisted many-objective evolutionary algorithm to solve computationally expensive MaOPs. The key features of the approach include: 1) the use of mul…
"Pian Kirjoitukset pyhiä, esineet taikakaluja" : matkamyytin ja metatasojen yhteenliittymät A. W. Yrjänän Somniassa ja CMX:n Cloaca Maxima II:ssa
2016
Analysoin pro gradu -tutkielmassani A. W. Yrjänän Somnia -runokokoelman ja hänen CMX-yhtyeensä Cloaca Maxima II -kokoelmalevyn myyttisen maailman, matkakuvaston ja metatasolla operoivien taiteiden suhteita. Tutkimukseni pohjana on hypoteesi, jonka mukaan tutkimusaineistoni matkakuvastolla, myyttisellä maailmankuvalla ja metareferentiaalisuudella on yhteys. Tutkimukseni keskeisimmät viitekehykset ovat runouden ja rocklyriikan tutkimus, myyttitutkimus ja kirjallisuuden metatasojen tutkimus. Käsittelen aineistoni runoja ja laulujen sanoituksia eri ilmaisuvälineiden teksteinä, mutta runoudentutkimuksen keinoin. Myyttitutkimuksen keskeisin teoria työssäni on Joseph Campbellin kehittelemä sankari…
Zastosowanie metody BIPOLAR na przykładzie problemu wyboru dostawcy usług logistycznych
2018
Idea metody BIPOLAR polega na tym, że warianty decyzyjne nie są porównywane bezpośrednio ze sobą a z zestawami rozwiązań wskazanych jako referencyjne. Takie porównanie umożliwia sprawdzenie czy istnieją przesłanki do uznania danego wariantu za mający przewagę nad każdym z pozostałych. Zbiór rozwiązań nazywa się zbiorem punktów referencyjnych, który zawiera rozwiązania dobre i złe. Metoda BIPOLAR uwzględnia wszystkie etapy procesu decyzyjnego: wybór kryteriów oraz określenie ich wag, modelowanie preferencji decydentów, wybór właściwego wariantu decyzyjnego na podstawie rankingu.
Caractérisation moléculaire de l’évolution des communautés microbiennes de sols du dispositif EFELE sur la période 2012-2021 : impact de l'apport de …
2022
It is becoming increasingly difficult to feed the growing population and it is therefore important to doeverything possible to improve our agriculture. To do this, a device called "EFELE" was created in 2012 toobserve how the soil reacts over a period of 20 years. This is essential for cultivation and allows us to obtainvarious information, including bio-indicators. The years 2012 and 2021 will be treated in order to define theamount of DNA in the soil, the microbial balance, the richness and diversity of the soil. In order to study howagriculture could be improved, different trials have been established. One of them studies the effects of theinput of organic waste products (OWPs) from live…