Search results for "EFT"

showing 10 items of 904 documents

Familial Left Ventricular Noncompaction Associated With a Novel Mutation in the Alpha-cardiac Actin Gene

2014

Pathologymedicine.medical_specialtybusiness.industrymedicineLeft ventricular noncompactionGeneral MedicinebusinessGeneNovel mutationAlpha-Cardiac ActinRevista Española de Cardiología (English Edition)
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Ceftazidime Determination in Serum by High-pressure Liquid Chromatography

2004

A rapid and sensitive high-pressure liquid chromatographic method with simple sample preparation was developed for the quantitative analysis of the beta-lactam antibiotic ceftazidime (CAS 78439-06-2, Fortum). A good linear relationship was established between the peak area and the amount of ceftazidime injected over a concentration range of 1 to 200 microg/ml. The detection limit of the method was calculated to be 0.9 microg/ml. Stability was shown at 4 degrees C and at -196 degrees C for time periods of 2 h and 84 days, respectively.

Peak areaDetection limitChromatographyChemistryReproducibility of ResultsCeftazidimeReference StandardsCeftazidimeHigh-performance liquid chromatographyCephalosporinsLinear relationshipSimple sampleDrug DiscoverymedicineHumansQuantitative analysis (chemistry)Chromatography High Pressure Liquidmedicine.drugAntibacterial agentArzneimittelforschung
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Half-width plots, a simple tool to predict peak shape, reveal column kinetics and characterise chromatographic columns in liquid chromatography: Stat…

2013

Peak profiles in chromatography are characterised by their height, position, width and asymmetry; the two latter depend on the values of the left and right peak half-widths. Simple correlations have been found between the peak half-widths and the retention times. The representation of such correlations has been called half-width plots. For isocratic elution, the plots are parabolic, although often, the parabolas can be approximated to straight-lines. The plots can be obtained with the half-widths/retention time data for a set of solutes experiencing the same kinetics, eluted with a mobile phase at fixed or varying composition. When the analysed solutes experience different resistance to mas…

Peak profiles in chromatography are characterised by their height position width and asymmetry; the two latter depend on the values of the left and right peak half-widths. Simple correlations have been found between the peak half-widths and the retention times. The representation of such correlations has been called half-width plots. For isocratic elution the plots are parabolic although often the parabolas can be approximated to straight-lines. The plots can be obtained with the half-widths/retention time data for a set of solutes experiencing the same kinetics eluted with a mobile phase at fixed or varying composition. When the analysed solutes experience different resistance to mass transfer the plots will be solute dependent and should be obtained with the data for each solute eluted with mobile phases at varying composition. The half-width plots approach is a simple tool that facilitates the prediction of peak shape (width and asymmetry) with optimisation purposes reveal the interaction kinetics of solutes in different columns and characterise chromatographic columns. This work shows half-width plots for different situations in isocratic elution including the use of different flows the effect of temperature the modification of the stationary phase surface by an additive the existence of specific interactions within the column and the comparison of columns. The adaptation to gradient elution is also described. Previous knowledge on half-width plots is structured and analysed to which new results are added.Work (thermodynamics)Column characterisationmedia_common.quotation_subjectKineticsLiquid chromatographyAnalytical chemistryHalf-widthsInteraction kineticsBiochemistryAsymmetryAnalytical ChemistryPeak shapeColumn (typography)Position (vector)Mass transferPhase (matter)media_commonChromatographyElutionChemistryOrganic ChemistryGeneral MedicineModels TheoreticalKineticsPredictionChromatography LiquidJournal of Chromatography A
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Orofacial features and medical profile of eight individuals with Kabuki syndrome

2019

Background To evaluate oral, craniofacial and systemic characteristics of eight patients with Kabuki syndrome (KS), aged between 3 and 16 years old. Material and Methods In this retrospective study, medical records of all patients were reviewed for information on family history, growth and development, medications in use, general systemic complications and oral and craniofacial characteristics. Results The medical alterations found included recurrent infections such as pneumonia and otitis media (n = 6), cardiovascular malformations (n = 4), kidney abnormalities (n = 2), epilepsy (n = 2) and visual deficiency (n = 2). The individuals exhibited dental caries (n = 5), agenesis (n = 5), delaye…

Pediatricsmedicine.medical_specialtyAdolescentCleft LipDental CariesAnodontia03 medical and health sciences0302 clinical medicinemedicineMicrodontiaHumansAbnormalities MultipleCraniofacialFamily historyChildGeneral DentistryAnodontiaRetrospective StudiesTooth Abnormalitiesbusiness.industryResearch030206 dentistryEnamel hypoplasia:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in Dentistrymedicine.diseaseHematologic DiseasesCleft Palatestomatognathic diseasesOtitisVestibular DiseasesOtorhinolaryngologyChild PreschoolFaceAgenesisUNESCO::CIENCIAS MÉDICASSurgerymedicine.symptombusinessKabuki syndromeMedicina Oral Patología Oral y Cirugia Bucal
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Aspetti etici e controllo di gestione dei farmaci antibiotici antibatterici

2010

Summary Introduction Antibacterial prescribing practices between 2004 and 2008 were investigated in the P. Giaccone University Hospital in Palermo, Italy to provide a foundation for critical analysis of the appropriateness of health-care resource usage. Materials and methods Antibiotic prescribing practices between 2004 and 2008 were analyzed in the hospital as a whole and in different specialty areas. Results were expressed as defined daily doses (DDD) as a function of bed-days, number of admissions, and Diagnosis Related Group (DRG) points. Results During the study period, increases were observed in the overall DDD per 100 bed-days (68.7 vs. 91.3) and the DDD per admission (4.53 vs. 5.54)…

Pediatricsmedicine.medical_specialtySettore MED/09 - Medicina Internabusiness.industryDiagnosis-related groupGeneral MedicineAmoxicillinMeropenemSettore MED/02 - Storia Della MedicinaCiprofloxacinAntibiotic therapy Ethics Management Defined Daily Doses (DDD)LevofloxacinChemoprophylaxisSettore BIO/14 - FarmacologiamedicineCeftriaxoneMedical prescriptionbusinessmedicine.drugItalian Journal of Medicine
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CLEFT PALATE ONLY: CURRENT CONCEPTS

2017

Cleft palate only (CPO) is one of the most common congenital malformations worldwide. The etiopathogenesis of CPO is not completely understood. Environmental factors, such as smoking, alcohol consumption, intake of drugs during pregnancy, advanced paternal age, have been demonstrated to be a risk of CPO, but conflicting results have also been published. Insufficient intake of folic acid during the pregnancy has been suggested to increase the risk for CPO. The demonstrated risk for siblings and the higher risk for monozygotic twins suggest a genetic etiopathogenesis for CPO. In some cases of CPO a prevalent mode of inheritance has been reported, but oligogenic models with reduced penetrance,…

Pediatricsmedicine.medical_specialtyWeaknessComplex diseasePrenatal diagnosisDiseaseCongenital03 medical and health sciences0302 clinical medicinemedicineGenetic epidemiologyOriginal Research Article030223 otorhinolaryngologyAerophagiaGeneral DentistryBirth defects; Cleft palate; Cleft palate only; Congenital; Genetic epidemiology; Dentistry (all)Pregnancybusiness.industrymedicine.diseasePenetranceBirth defectsCleft palate onlyCleft palate030220 oncology & carcinogenesisDentistry (all)Unintelligible speechmedicine.symptombusinessOral & Implantology
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Pulmonale Hypertonie bei Linksherzerkrankungen

2010

The 2009 European Guidelines on Diagnosis and Treatment of Pulmonary Hypertension have been adopted for Germany. While the guidelines contain detailed recommendations regarding pulmonary arterial hypertension (PAH), they contain only a relatively short paragraph on other, much more frequent forms of PH such as PH due to left heart disease. Despite the lack of data, targeted PAH treatments are increasingly being used for PH associated with left heart disease. This development is of concern. On the other hand, PH is a frequent problem that is highly relevant for morbidity and mortality in patients with left heart disease, so that it may be speculated whether selected patients may benefit from…

Pediatricsmedicine.medical_specialtybusiness.industryConsensus conferenceMEDLINEGeneral Medicinemedicine.diseasePulmonary hypertensionlanguage.human_languageGermanRespiratory MedicineHeart failuremedicinelanguageLeft heart diseasebusinessIntensive care medicineWorking groupDMW - Deutsche Medizinische Wochenschrift
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Exercising recommendations for paroxysmal AF in young and middle-aged athletes (PAFIYAMA) syndrome.

2017

We have recently described a new syndrome: strenuous endurance exercise-related atrial fibrillation (AF) under the acronym of ‘paroxysmal AF in young and middle-aged athletes’ (‘PAFIYAMA’). Provided that other risk factors for AF and underlying conditions have been excluded (1), the diagnostic criteria for this syndrome entail a number of conditions, classified as major and minor. An enhanced risk of AF has been clearly documented in endurance athletes (top-class, elite and recreational) (2-5), and such risk typically ranges between 1.2- to 15-fold compared to the general, sedentary population (the better cardiovascular fitness, the higher incidence of AF) (6-11). Anecdotally, the last auth…

Pediatricsmedicine.medical_specialtymedicine.medical_treatmentPopulation030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineViewpointrecommendations paroxysmal AF athletesLeft atrial enlargementMedicine030212 general & internal medicineeducationCardiovascular fitnessFirst episodeparoxysmal AFeducation.field_of_studybiologybusiness.industryAthletesIncidence (epidemiology)Atrial fibrillationCryoablationGeneral Medicinemedicine.diseasebiology.organism_classificationathletesrecommendationsbusinessAnnals of translational medicine
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Die Verteilung von Noradrenalin und Adrenalin im Herzen der Katze, des Kaninchens und der Ratte

1958

The concentration of noradrenaline in different parts of the heart was estimated in cats, rabbits, and rats. In each heart, the concentration of noradrenaline was much higher in the right atrium than in the left atrium and higher in the right ventricle than in the left one.

PharmacologyCATSbusiness.industryLeft atriumMyocardium metabolismCell BiologyAnatomyCellular and Molecular Neurosciencemedicine.anatomical_structureVentriclecardiovascular systemmedicineEpinephrine metabolismMolecular MedicineRight atriumcardiovascular diseasesbusinessMolecular BiologyExperientia
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Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates.

1994

The relationship between intracellular energy parameters and myocardial O2 consumption (VO2) was studied in control and volume-overloaded hearts perfused with different lipid substrates and over a range of left ventricular work loads. In control hearts, a unique linear relationship between log of cytosolic [ATP]/[ADPf].[Pi] (where [ADPf] is concentration of free ADP) and myocardial VO2 was observed between low and high work loads for both fatty acids studied. In volume-overloaded hearts perfused in the presence of exogenous palmitate, the slope of the relationship between log [ATP]/[ADPf].[Pi] and myocardial VO2 was considerably depressed. It would seem that, under these conditions, much o…

PhosphocreatinePhysiologyRespiratory chainPalmitic AcidCardiomegalyPalmitic AcidsIn Vitro TechniquesVentricular Function LeftPhosphatesAdenosine TriphosphateOxygen ConsumptionPhysiology (medical)RespirationPiAnimalsRespiratory systemRats WistarATP synthasebiologyMyocardiumSubstrate (chemistry)HeartCreatineNADRatsAdenosine DiphosphateCytosolBiochemistrybiology.proteinCaprylatesCardiology and Cardiovascular MedicineEnergy MetabolismIntracellularThe American journal of physiology
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