Search results for "EKIN"
showing 10 items of 195 documents
All they need is love? Placing romantic stress in the context of other stressors: A 17-nation study
2010
The present study focuses on romantic stress and coping styles in the context of identity and future-related stressors in 8,654 adolescents with a mean age of M = 15.3; SD = 1.84. The adolescents from 17 countries were grouped into seven regions, i.e., Mid-Europe, Northern Europe, Eastern Europe, Southern Europe, South Africa, South America, and the Middle East. Future-related stressors were perceived as being more stressful than romantic stressors by all adolescents, irrespective of the region in which they lived. Identity-related stressors were of greater concern to adolescents from South Africa, South America, and the Middle East. Romantic stress was much higher in adolescents from Mid-…
P717 Ustekinumab in Crohn’s disease: Real-world outcomes from the Sicilian Network for inflammatory bowel diseases (SN-IBD):–Preliminary results
2020
Abstract Background Ustekinumab is approved in Europe for the treatment of moderate-to-severe Crohn’s disease (CD) since 2016. Italian real-life data on efficacy and safety are scarce. The aim of this study was to assess effectiveness, safety and usage of Ustekinumab in an Italian cohort of patients. Methods Data of patients with moderate-to-severe CD who started Ustekinumab in Sicily were extracted from the database of the SN-IBD. Demographic data, disease-related data (disease duration, location, clinical activity) and previous therapies with biologics were collected. The primary study endpoints were steroid-free clinical remission and steroid-free clinical response at week 12, 24 and 52 …
Information needs and uses: An analysis of the literature published in Spain, 1990–2004
2007
This article presents a descriptive analysis of works published in Spanish journals and of the papers of conferences held in Spain in the field of information needs and uses in the period 1990–2004 in order to determine if the change in approach described by Dervin and Nilan, among others, also occurred outside the English speaking world. An analysis of the characteristics of relevant publications in this field (by year, authorship, type of document, type of work, and means of publication) shows that although activity is increasing, information needs and uses have not yet become a well-established area. In addition, a study of the content characteristics (by type of user, methodology used, …
Influence of the Novelty-Seeking Endophenotype on the Rewarding Effects of Psychostimulant Drugs in Animal Models
2015
Novelty seeking (NS), defined as a tendency to pursue novel and intense emotional sensations and experiences, is one of the most relevant individual factors predicting drug use among humans. High novelty seeking (HNS) individuals present an increased risk of drug use compared to low novelty seekers. The NS endophenotype may explain some of the differences observed among individuals exposed to drugs of abuse in adolescence. However, there is little research about the particular response of adolescents to drugs of abuse in function of this endophenotype, and the data that do exist are inconclusive. The present work reviews the literature regarding the influence of NS on psychostimulant reward…
Cross-reinstatement between 3,4-methylenedioxypyrovalerone (MDPV) and cocaine using conditioned place preference.
2019
Abstract 3,4-Methylenedioxypyrovalerone (MDPV) is a new psychoactive substance (NPS) considered to be a cocaine-like psychostimulant. The substitution of an established illicit drug as cocaine with an NPS is a pattern of use reported among drug users. The aim of this study was to investigate the relationship between cocaine and MDPV in the reinstatement of the conditioned place preference (CPP) paradigm, in order to establish whether there is cross-reinstatement between the two psychostimulants. Four experimental groups of male OF1 mice were subjected to the CPP paradigm: MDPV-MDPV, Cocaine-Cocaine, Cocaine-MDPV, and MDPV-Cocaine. The first drug refers to the substance with which the animal…
Changing Trends in Drug Prescription and Causes of Treatment Discontinuation of First Biologic Over Ten Years in Psoriasis in the Spanish Biobadaderm…
2020
Background and objectives: Current psoriasis guidelines do not usually include recommendations about first line classical or biologic treatment. The objectives of this study were: to describe shifts in the prescription of the first biological treatment, and to compare treatment withdrawal and rates of adverse events over ten years. Material and methods: Biobadaderm registry was analyzed to describe: first biological prescription in bio-naive patients, adverse events rate and reasons for drug withdrawal comparing three periods of time (2008-2010, 2011-2014, 2015-2018). Results: Anti-TNF drugs were the most prescribed biological drug from 2008 to 2010. Ustekinumab has become the most prescrib…
Decentralization and growth: what if the cross-jurisdiction approach had met a dead end?
2013
International audience; The relationship between decentralization and economic growth is generally studied from a perspective stressing universal or quasi-universal regularities across jurisdictions. That approach has generated many insights but seems to reach its limits. The paper explains why it allows contrasting positions with regard to the benefits of decentralization even among proponents of free and competitive markets. And it seems from the empirical literature that no robust and economically significant cross-jurisdiction relation between decentralization and economic performance or growth, except perhaps their independence, has been found. The absence of a relation valid across ju…
U.I.R.D.A. – Unbuilt Italian Rationalism Digital Archive
2018
For twenty years, the architecture of Italian rationalism through the digital modelling has been investigated. Very often, the production of a model and the consequent representation of tridimensional views, in many case studies, as outcome of the research on architecture have been considered. Actually, the digital model, intended as a critical tool, has to be conceived as a ‘starting point' for graphic analysis of architecture and not as the outcome. Indeed, it is associated to other graphics, sometimes not ‘deducted' from the model, useful for the understanding/translation of architecture. The construction of the model is not the construction of a simple image, operation, which is often c…
Smart Tools for Academic Information Seeking
2016
Systematic information seeking is an essential part of academic work. Research and information seeking go hand in hand, and both need planning. In the academic world you can hardly avoid the research plan, but you probably won’t hear that much about the information seeking plan. The information seeking plan guides you through the research process from the first sparks of an idea to the last dot in the bibliography from the point of view of the often invisible process of systematic information seeking.Systematic Information Seeking Framework designed in the Jyväskylä University Library has its roots in Carol Kuhlthau's Guided Inquiry Design Process. Our model, designed for more contextual ad…
When cooler heads prevail: peacemakers in a sports riot.
1999
Male sports fans (N = 74) were asked to estimate the likelihood that they would intervene in a crowd disturbance in an attempt to stop the fighting. They also completed a battery of measures that included their attitude toward law and order, fight history, the false consensus effect, impulsivity, psychopathy, sensation seeking, anger, physical aggression and identification with their favorite team. Law and order, body mass, anger and the false consensus effect were positively related to peacemaking whereas sensation seeking was negatively related. A multiple regression analysis yielded a solution that accounted for 32.3% of the variance with anger and attitude toward law and order emerging …