Search results for "ELECTROSPINNING"

A biostable, anti-fouling zwitterionic polyurethane-urea based on PDMS for use in blood-contacting medical devices.

2020

Polydimethylsiloxane (PDMS) is commonly used in medical devices because it is non-toxic and stable against oxidative stress. Relatively high blood platelet adhesion and the need for chemical crosslinking through curing, however, limit its utility. In this research, a biostable PDMS-based polyurethane-urea bearing zwitterion sulfobetaine (PDMS-SB-UU) was synthesized for potential use in the fabrication or coating of blood-contacting devices, such as a conduits, artificial lungs, and microfluidic devices. The chemical structure and physical properties of synthesized PDMS-SB-UU were confirmed by (1)H-nuclear magnetic resonance ((1)H-NMR), X-ray diffraction (XRD), and uniaxial stress-strain cur…

Microemulsion encapsulated into halloysite nanotubes and their applications for cleaning of a marble surface

2018

Halloysite nanotubes were used to incorporate anionic surfactant micelles and an organic solvent to generate a cleaning system to be applied in Cultural Heritage restoration. The targeted adsorption is driven by electrostatic interactions based on the nanotubes peculiar charge separation. Namely anionic species are driven to the positively charged inner surface while being prevented from interacting with the halloysite outer surface that possesses a positive charge density. The hybrid organic/inorganic emulsion was characterized by dynamic light scattering. Analysis of the autocorrelation function allowed us to define the presence of surfactant aggregates inside/outside the nanotube lumen a…

Preparation, characterization and hydrolytic degradation of PLA/PCL co-mingled nanofibrous mats prepared via dual-jet electrospinning

2017

Abstract PLA/PCL co-mingled nanofibrous mats were prepared via multi-jet electrospinning. The concentration of PLA and PCL in the co-mingled mats were controlled by changing the flow rate of the two polymer solutions. The amount of PLA and PCL in the co-mingled nanofibrous mats was monitored by UV–Vis measurements through a colored dye added to PLA and by FTIR-ATR analysis. Morphology and mechanical properties of the nanofibrous mats were respectively examined by scanning electron microscopy (SEM) and tensile tests. Water contact angles measurements were also carried out in order to investigate the wettability of the materials. Finally, the hydrolytic degradation of the mats in buffer solut…

Characterization of electrospun poly(lactide) composites containing multiwalled carbon nanotubes

2019

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors would like to thank the Ministry of Education, Science and Technological Development, Republic of Serbia, for funding projects III45022 and 172056 and European Cooperation in Science and Technology (COST) action CA15107.

Microfibrillar polymeric ocular inserts for triamcinolone acetonide delivery.

2019

Abstract Despite eye drops generally represent the most convenient, simple and patient-friendly formulations to treat ocular diseases, they suffer from poor retention on the ocular surface and low drug bioavailability leading to the necessity of prolonged and continuous treatment over time. Therefore, ocular insert could represent an innovative way to benefit from ocular topical administration while minimizing all the relevant limitation related to this route of administration. Polymeric non-erodible mucoadhesive ocular inserts should be comfortable and should rapidly adhere on the ocular surface, remain in situ for prolonged period, assure a reproducible and controlled drug release as well…

Electrospinning of α,β-poly(N-2-hydroxyethyl)-dl-aspartamide-graft-polylactic acid to produce a fibrillar scaffold

2010

Abstract α,β-Poly( N -2-hydroxyethyl)- dl -aspartamide grafted with polylactic acid (PHEA- g -PLA) is a biocompatible and biodegradable amphiphilic copolymer that has been already employed to prepare a drug delivery system. In this study we have prepared for the first time a fibrillar scaffold from PHEA- g -PLA by the electrospinning of a solution of this copolymer in a mixture of N , N -dimethyl formamide (DMF) and acetone (80:20 vol/vol). The average diameter and the morphology of electrospun fibers were detected by scanning electron microscopy. Chemical degradation studies in phosphate buffer solution pH 7.4 have been performed until 15 days in order to obtain a preliminary information a…

ELECTROSPUN NANOFIBROUS MATS IN FIBRE REINFORCED EPOXY LAMINATES

Engineering in-plane mechanics of electrospun polyurethane scaffolds for cardiovascular tissue applications

2021

Effective cardiovascular tissue surrogates require high control of scaffold structural and mechanical features to match native tissue properties, which are dependent on tissue-specific mechanics, function heterogenicity, and morphology. Bridging scaffold processing variables with native tissue properties is recognized as a priority for advancing biomechanical performance of biomedical materials and, when translated to the clinical practice, their efficacy. Accordingly, this study selected electrospinning on a rotating cylindrical target as an apparatus of broad application and mapped the relationship between key processing variables and scaffold mechanics and structure. This information was…

Electrospun nanofibers: role of nanofibers in water remediation and effect of experimental variables on their nano topography and application process…

2021

Water is the elixir of life and the most elementary need for the survival of human beings on planet Earth. With rapid industrialization, globalization and human exploitation, natural water resources are diminishing at a startling rate wherein availability of potable water has drastically decreased in recent times and hence membrane technology is a highly pursued area for water purification. The simple and cost-effective electrospinning technique has evolved to be a state-of-the-art method for developing nanofibers of tailored thickness and diameters by combining a broad range of starting materials. This comprehensive review emphasizes on the demonstration of electrospun nanofibers based on …

High throughput electro-hydrodynamic processing in food encapsulation and food packaging applications: Viewpoint

2017

Abstract Looking genuinely at nature, nanofibers often serve as a basic platform where either organic or inorganic components are built upon. The fiber structure exhibits, from a structural point of view, the intrinsic ability to mechanically reinforce materials but also the less well-known property of enhancing the barrier performance of polymer matrices when applied smartly. To reproduce and tailor this extraordinary nature's design, a reliable technology that is able to fabricate fiber nanostructures from a variety of materials with size and size distribution control and composition flexibility is highly desirable. In addition, if this technology could allow nanofiber shortening to achie…