Search results for "EMBER"

showing 10 items of 549 documents

International Bankruptcy in Spain

2011

International Bankruptcy Law is a very trendy topic. Many countries have reformed their national Acts seeking to adapt them to the current economic situation. Also Spain did this some years ago. The New Spanish Bankruptcy Act of 2003 includes some rules on International Bankruptcy. These rules are directly linked to the EU Regulation on cross-border insolvency and depend on it. The article analyze in depth solutions embodied in the Act and their -not always easy- relationship with the Regulation. Something that happens in some other EU Member States.

InsolvencyEconomic situationbusiness.industryBankruptcyMember statesAccountingBankruptcy ActBusinessLaw and economicsSSRN Electronic Journal
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Interleukin-12 and -23 Control Plasticity of CD127(+) Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria.

2015

Human group 1 ILCs consist of at least three phenotypically distinct subsets, including NK cells, CD127(+) ILC1, and intraepithelial CD103(+) ILC1. In inflamed intestinal tissues from Crohn's disease patients, numbers of CD127(+) ILC1 increased at the cost of ILC3. Here we found that differentiation of ILC3 to CD127(+) ILC1 is reversible in vitro and in vivo. CD127(+) ILC1 differentiated to ILC3 in the presence of interleukin-2 (IL-2), IL-23, and IL-1β dependent on the transcription factor RORγt, and this process was enhanced in the presence of retinoic acid. Furthermore, we observed in resection specimen from Crohn's disease patients a higher proportion of CD14(+) dendritic cells (DC), whi…

Interleukin 2Receptors Retinoic AcidCellular differentiationCD14ImmunologyInterleukin-1betaRetinoic acidLipopolysaccharide Receptorschemical and pharmacologic phenomenaTretinoinMice SCIDBiologyInterleukin-12 Subunit p35Interleukin-7 Receptor alpha Subunitchemistry.chemical_compoundMiceIntestinal mucosaCrohn DiseaseMice Inbred NODmedicineImmunology and AllergyAnimalsHumansRetinoid X Receptor gammaLymphocytesIntestinal MucosaInterleukin-7 receptorCells CulturedMice KnockoutRetinoic Acid Receptor alphaInnate lymphoid cellvirus diseaseshemic and immune systemsCell DifferentiationDendritic CellsNuclear Receptor Subfamily 1 Group F Member 3Molecular biologyKiller Cells NaturalMice Inbred C57BLInfectious DiseaseschemistryLymphocyte TransfusionImmunologyInterleukin 12Interleukin-23 Subunit p19Interleukin-2medicine.drugImmunity
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EU external policy at the crossroads: The challenge of actorness and effectiveness

2013

The goal of this Special Issue is to improve our conceptualisation and empirical understanding of EU actorness and effectiveness in International Relations. While the European Union aspires to play a greater global role, its actorness and effectiveness cannot be taken for granted given the nature of the EU as a multi-level and semi-supranational polity encompassing 28 Member States with diverse foreign policy preferences. The EU is presently at an important crossroad. On the one hand, its external policy stature and capacity have been boosted by institutional innovations and by the Union’s increased involvement in the full spectrum of international issues. On the other hand, a number of fa…

International relationsMember statesContext (language use)World orderForeign policyLawPolitical economyPolitical Science and International Relationsmedia_common.cataloged_instanceSociologyPolityEuropean unionSovereign debtmedia_commonInternational Relations
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The European Union in a Changing World Order: What Is at Stake?

2019

This introductory chapter aims to shed light on how tightly the EU and the liberal international order are entwined and discuss the likely impact on the EU of a changing and, most likely, less liberal world order. The chapter discusses the concept of order in international politics and analyses how the liberal order that emerged after WWII has effected the development of the EU. The chapter introduces the book’s interdisciplinary, holistic approach, and discusses how a changing world order is affecting the EU and how the EU, in turn, is trying to shape the emerging new order by recalibrating its policies and actions in various domains, ranging from its relations with the rest of the world, …

International relationsOrder (exchange)Political sciencePolitical economyMember statesWorld War IImedia_common.cataloged_instanceWorld orderLiberal democracyEuropean unionmedia_common
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Presence of Blastocystis in gut microbiota is associated with cognitive traits and decreased executive function.

2022

Growing evidence implicates the gut microbiome in cognition. Blastocystis is a common gut single-cell eukaryote parasite frequently detected in humans but its potential involvement in human pathophysiology has been poorly characterized. Here we describe how the presence of Blastocystis in the gut microbiome was associated with deficits in executive function and altered gut bacterial composition in a discovery (n = 114) and replication cohorts (n = 942). We also found that Blastocystis was linked to bacterial functions related to aromatic amino acids metabolism and folate-mediated pyrimidine and one-carbon metabolism. Blastocystis-associated shifts in bacterial functionality translated into …

Intestins--MicrobiologiaMicrobiologiaPathogenesisBlastocystis InfectionsMicrobiologyMETAGENOMICSMEMBERExecutive FunctionMicegut microbiota ; Blastocystis ; executive function ; gut microbiome-brain axis.CognitionAparell digestiuDiagnosisAnimalsHumansEcology Evolution Behavior and SystematicsBlastocistMEMORYDNAGastrointestinal MicrobiomeCognicióBlastocystisBlastocist -- InfeccióMicrobiomaBiomarkersThe ISME journal
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Diagnosis and therapeutic management of primary headache in an emergency setting

2013

Introduction and aim: Much headachers are under or mis-diagnoses and data regarding the proportion of patients attending an emergency department (ED) because of headache are still few. We conducted a retrospective observational study in an ED with the following aims: (a) estimate the proportion of headache attending to an ED (b) to estimate and describe the therapeutic management of primary headache and (c) to assessment the exam most frequently requested. Materials and methods: We collected data regarding patients diagnosed with headache consecutively attending the ED of the University of Palermo between September 2011 and March 2012. The study was approved by the ethics committee. Results: Between the semester evaluated 25110 subjects were admitted to ED headache suffers were equal to 1.6 %. Of these 263 (63.1 %) were woman and 154 (36.9 %). Mean age was 44.2 (DS ± 18.4) years (p = 0.068).According to ED registry headache admission was as follow assigned: 76.5 % with a diagnosis of headache 22.8 % with a secondary headache 0.7 % with Trigeminal Autonomic Cephalgias (TACs). Among those with a primary headache about 36 % of patient did not received a pharmacological treatment. Monotherapy was prescribed less frequently than combination therapy (19.1 vs 44.5 %).In monotherapy the most frequent medication were NSAIDs (28.3 %) benzodiazepines (26.7 %) and dopamine antagonists (11.7 %). Among those with a primary headache a CT scan was performed in the 124 subjects and 111 (34.8 %) had a neurologist consultation. Discussion: Our data are in line with the one previously reported in literature. The most frequently medication in the Italian ED were NSAIDs benzodiazepines dopamine antagonists and steroids. Neverless our data unlikely can be compared to other study give a snapshot. We believe that much more can be done to improve treatment of primary headache in ED.Settore MED/26 - Neurologia
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Les juristes ouest-allemands et le "procès des juristes" de Nuremberg: Analyse d'une (non?)-réception

2016

Der Beitrag untersucht den Nürnberger Juristenprozess von 1947 in einer doppelten Perspektive: Einerseits wird der Schwerpunkt auf die unmittelbare Rezeption des Urteils in der Fachöffentlichkeit gelegt. Hauptquellen der Untersuchung sind dabei die damaligen Fachzeitschriften und Protokolle von Juristentagungen. Dieser Ansatz ermöglicht, durch eine differenzierte Analyse der Komplexität der damaligen Diskurse (wie im Fall des berühmten Aufsatzes Gustav Radbruchs zum Prozess) gerechter zu werden. Andererseits wird diese Rezeption in den breiteren Zusammenhang des Standesbewusstseins und des Berufsethos der Juristen gestellt. Es stellt sich heraus, dass das schon in der Weimarer Zeit stark au…

Juristen[ SHS ] Humanities and Social SciencesGustav RadbruchJuristenprozess[SHS] Humanities and Social SciencesProcès de NurembergNuremberg TrialsJuristes allemandsLawyers and juristsEthique professionnelleNürnberger Prozesse[SHS]Humanities and Social Sciences
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Fluorinated Heterocyclic Compounds. An Effective Strategy for the Synthesis of Fluorinated Z-Oximes of 3-Perfluoroalkyl-6-phenyl-2H-1,2,4-triazin- 5-…

2005

The reaction of 3-benzoyl-5-perfluoroalkyl-1,2,4-oxadiazoles with hydrazine has been investigated, evidencing the possibility of competitive reaction paths. Nucleophilic addition of the hydrazine to the electrophilic C(5) of the 1,2,4-oxadiazole ring, followed by ring opening and ring closure with enlargement, leads with high yield and in very mild experimental conditions to the formation of Z-oximes of 3-perfluoroalkyl-6-phenyl-2H-1,2,4-triazin-5-ones (11a-c) as major products of the reaction. In turn, the hydrazine can attack the electrophilic carbonyl carbon giving 4-perfluoroacylamino-5-phenyl-2H-1,2,3-triazoles (13a-c) through the well-known Boulton-Katritzky rearrangement of the inter…

KetoneTRANSFORMATIONSHydrazineHydrazoneRing (chemistry)Medicinal chemistryChemical synthesisTurn (biochemistry)chemistry.chemical_compoundCHEMISTRYROUTE3-BENZOYL-5-PHENYL-124-OXADIAZOLEOrganic chemistrychemistry.chemical_classificationNucleophilic additionDERIVATIVESOrganic ChemistryREARRANGEMENTS25-BIS(TRIFLUOROMETHYL)-134-OXADIAZOLE124-TRIAZINESSettore CHIM/06 - Chimica OrganicaGeneral MedicineOximeAROMATICITY INDEXchemistryHeterocyclic compoundYield (chemistry)ElectrophileTriazole derivatives5-MEMBERED HETEROCYCLESThe Journal of Organic Chemistry
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Enhancing citizen response to crises through communication : investigating expert views

2015

The purpose of this paper is to clarify how citizen response to crises is currently being enhanced, and how it might be increased, by emergency response organisations in member states of the European Union via communication strategies and tools. Data were gathered via an online questionnaire directed at emergency management and crisis communication experts working in the field of crisis response. The experts were drawn from the database of an international conference. The results indicate that while the importance of involving citizens in crisis response is generally acknowledged, the implementation of such activities is often fragmented. Although some initiatives are under way, coherent st…

Knowledge management050801 communication & media studiesCrisis managementComputer-assisted web interviewingkriisiviestintä0508 media and communicationsPolitical scienceLagrangian coherent structuresmedia_common.cataloged_instanceta518crisis managementEuropean unioncrisis communicationmedia_commonCrisis communicationEmergency managementbusiness.industryMember states05 social sciences050301 educationPublic relationscommunity approachEmergency responsecitizen responseEmergency Medicinebusiness0503 educationkriisinhallinta
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Integrating business start-up indicators in the flexicurity concept to cover the alternative forms of employment

2016

The flexicurity concept created in the Netherlands and Denmark in the early 1990s has become the main stepping-stone in improving the performance of labour markets across the European Union Member States. The European Commission has therefore taken a leading role on broader flexicurity concept development and creation of the data analysis methodology. However, the analysis proposed by the European Commission Joint Research Centre on flexicurity indicators in 2010 only partly includes business start-ups as a flexible form of employment. This research starts the discussion on whether additional indicators should be integrated in the flexicurity analysis, because of the rising need for employm…

Knowledge managementCover (telecommunications)Economic policybusiness.industryMember statesConcept developmentStart upJoint researchmedia_common.cataloged_instanceEuropean commissionBusinessEuropean unionmedia_commonFlexicurity9th International Scientific Conference “Business and Management 2016”
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