Search results for "EPIDEMIOLOGIA"
showing 10 items of 118 documents
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch r…
2022
Abstract Objective To compare colorectal cancer (CRC) incidences in carriers of pathogenic variants of the MMR genes in the PLSD and IMRC cohorts, of which only the former included mandatory colonoscopy surveillance for all participants. Methods CRC incidences were calculated in an intervention group comprising a cohort of confirmed carriers of pathogenic or likely pathogenic variants in mismatch repair genes (path_MMR) followed prospectively by the Prospective Lynch Syndrome Database (PLSD). All had colonoscopy surveillance, with polypectomy when polyps were identified. Comparison was made with a retrospective cohort reported by the International Mismatch Repair Consortium (IMRC). This com…
Niewydolność serca w województwie opolskim – epidemiologia i perspektywy na przyszłość
2019
Niewydolność serca występuje u około 2% dorosłej populacji w Europie. U jednej na pięć osób w wieku 40 lat podczas dalszego życia dojdzie do rozwoju niewydolności serca. Dolegliwość ta dotyka 20 000 osób w województwie opolskim. Zaostrzenie niewydolności serca, w różnych postaciach, jest drugą, po ostrych zespołach wieńcowych, przyczyną pilnych przyjęć do Kliniki Kardiologii Uniwersyteckiego Szpitala Klinicznego w Opolu. W opracowaniu przedstawiono prognozę hospitalizacji pacjentów z niewydolnością serca na lata 2015−-2050 uwzględniającą procesy depopulacji zachodzące w województwie opolskim. Analiza pozwala przewidzieć, że grupą wiekową szczególnie narażoną na tego typu zachorowanie w najb…
Efficient design and modeling strategies for follow-up studies with time-varying covariates
2015
Epidemiological studies can often be designed in several ways, some of which may be more optimal than others. Possible designs may differ in the required resources or the ability to provide reliable answers to the questions under study. In addition, once the data are collected, the selected modeling approach may affect how efficiently the data are utilized. The purpose of this dissertation is to investigate efficient designs and analysis meth ods in follow-up studies with longitudinal measurements. A key question is how to select optimally a subcohort for a new longitudinal covariate measurement if we cannot afford to measure the entire cohort. Another key question we consider is how to determine …
Maantieteelliset piirteet ja iäkkäiden henkilöiden liikkuminen ulkona (GEOage)
2021
This dataset is part of the “Geographic characteristics, outdoor mobility and physical activity of older people” (GEOage) project, in which freely available geographic information characterizing the environment is linked to participant data of the “Life-space mobility in old age” (LISPE) cohort comprising 75–90-years-old community-dwelling people living in Jyväskylä and Muurame in Central Finland (n=848). The GEOage dataset contains variables of environmental characteristics of participants' environment within 500 or 1000 m from home. The dataset comprises variables related to characteristics of nature (hilliness, nature and green areas, waterside areas) and built environment (land use, nei…
The Influence of Infection and Colonization on Outcomes in Inpatients With COVID-19 : Are We Forgetting Something?
2021
The COVID-19 epidemic has been a great challenge to health systems and especially hospitals. A prospective observational epidemiological study was planned as of February 26, 2020 in a tertiary hospital in the Valencia region. The total number of patients followed up with complete information during the first year was 2,448. Among other variables, the comorbidities of the patients were collected (and grouped in the Charson index), the stay in the intensive care unit (ICU), the co-infections, and the colonizations. Data on nosocomial infections due to said virus were also collected. The median days from the onset of symptoms to diagnosis were 4 + 4.6, while an additional 4.4 days had to pass …
Prevalence of biopsied oral lesions in a Department of Oral Surgery (2007 - 2009)
2011
Objectives: To determine the prevalence of the hard and soft tissue lesions biopsied in the Department of Oral Surgery of the Barcelona University Dental Clinic (Barcelona, Spain). Study design: A retrospective descriptive study was made of the biopsies performed between January 2007 and April 2009 in our Department of Oral Surgery. The following variables were recorded: age, the sex, location of the lesion, the biopsy technique, the reason for consultation, and the histological result obtained. Results: A total of 460 lesions amenable to histological analysis and corresponding to 450 patients were analyzed. The most frequently biopsied lesions were maxillary cysts, including particularly r…
Diet-disease relationships : recent advances in nutritional epidemiology
2020
Nutritional epidemiology currently studies the diet-disease relationships. In order to evaluate these associations, an accurate estimation of nutritional exposure is essential. Traditional dietary questionnaires are being complemented with the measurement of nutritional biomarkers. New methodologies, including the use of new dietary assessments, metabolomics for increasing the quantity and quality of biomarkers, and statistical approaches to combine both techniques, are required to move forward this field. In this review, we have selected five of the more relevant accomplishments in this field as examples of the importance of dietary factors in the prevention of non-communicable diseases. T…
Epidemiology of foodborne Norovirus outbreaks in Catalonia, Spain
2008
Abstract Background Noroviruses are one of the principal biological agents associated with the consumption of contaminated food. The objective of this study was to analyse the size and epidemiological characteristics of foodborne outbreaks of gastroenteritis in Catalonia, a region in the northeast of Spain. Methods In all reported outbreaks of gastroenteritis associated with food consumption, faecal samples of persons affected were analysed for bacteria and viruses and selectively for parasites. Study variables included the setting, the number of people exposed, age, sex, clinical signs and hospital admissions. The study was carried out from October 2004 to October 2005. Results Of the 181 …
Leaps and bounds : towards an integrative theory of cultural evolution
2014
Tutkimuksessa pyritään yhdistämään ajatus kulttuurista eräänlaisen luonnonvalinnan alaisena Dan Sperberin näkemyksien (1) kommunikaation taustadynamiikasta tarkoitet-tujen merkityksien päättelynä niiden kontekstisidonnaisen merkittävyyden perusteella ja (2) erilaisten käsityksien eri kohteista leviämisen suhteen. Tällaisen yhdentävän viiteke-hyksen turvin pyritään vastaamaan pätevästi Sperberin kritiikkiin koskien darwinilaisen luonnonvalinnan soveltamista kulttuurin ilmiöihin. Näihin kritiikkeihin lukeutuvat väitteet, että (1) kulttuurin muutostiheys on liian korkea evoluution tuloksien kasautumisen mahdol-listamiseksi, (2) yleistykset koskien sisältöjä ovat kestämättömiä tehtyjen yliyksin…
Niewydolność serca - problem medyczny, ekonomiczny i społeczny
2019
Pierwsze wzmianki o chorobie, którą dzisiaj określamy jako niewydolność serca, pochodzą z czasów antycznych. Epidemiologia objawowej niewydolności serca jest dobrze poznana, szczególnie w Europie. Na naszym kontynencie niewydolność serca występuje u około 2% dorosłej populacji. W artykule przedstawiono: defnicję, epidemiologię i rokowanie chorych z niewydolnością serca. Opracowanie charakteryzuje aktualne metody farmakoterapii i leczenia interwencyjnego. Ważnym elementem postępowania u chorych z niewydolnością serca jest rehabilitacja medyczna i przestrzeganie zasad proflaktyki chorób sercowo-naczyniowych zalecanych przez Europejskie Towarzystwo Kardiologiczne. Artykuł porusza również temat…