Search results for "EPO"

showing 10 items of 6062 documents

Metabolic detoxification: implications for thresholds.

2000

The fact that chemical carcinogenesis involves single, isolated, essentially irreversible molecular events as discrete steps, several of which must occur in a row to finally culminate in the development of a malignancy, rather suggests that an absolute threshold for chemical carcinogens may not exist. However, practical thresholds may exist due to saturable pathways involved in the metabolic processing, especially in the metabolic inactivation, of such compounds. An important example for such a pathway is the enzymatic hydrolysis of epoxides via epoxide hydrolases, a group of enzymes for which the catalytic mechanism has recently been established. These enzymes convert their substrates via…

040301 veterinary sciencesDNA damageEpoxide10050 Institute of Pharmacology and Toxicology610 Medicine & healthToxicology030226 pharmacology & pharmacyPathology and Forensic MedicineXenobiotics0403 veterinary science1307 Cell Biology03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEnzymatic hydrolysis1312 Molecular BiologyAnimalsHumansComputer SimulationEpoxide hydrolaseMolecular BiologyCarcinogenchemistry.chemical_classificationEpoxide HydrolasesDose-Response Relationship Drug3005 Toxicology04 agricultural and veterinary sciencesCell Biology2734 Pathology and Forensic MedicineEnzymechemistryBiochemistryCovalent bondEpoxide HydrolasesInactivation MetabolicCarcinogensMicrosomes Liver570 Life sciences; biologyMutagensToxicologic pathology
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The effects of playing tactics on creating scoring opportunities in random matches from US Major League Soccer

2015

The aim of this study was to examine the effects of playing tactics on the creation of scoring opportunities in random matches from US Major League Soccer 2014, taking into account both contextual and defensive variables. The sample included 3253 team possessions corresponding to 30 randomly selected matches. Multidimensional qualitative data from 10 categorical variables was analysed by means of descriptive analysis and multiple logistic regression analysis. Contextual variables such as match location (p=0.049), match half (p=0.043) and match status (P=0.032) were associated with creating scoring opportunities. With regards playing tactics, set plays created a higher proportion of scoring …

05 social sciencesFootballEffectivenessPhysical Therapy Sports Therapy and RehabilitationAdvertising030229 sport sciencesFootballLeague050105 experimental psychologyMatch analysisMatch analysis03 medical and health sciencesOffensive play0302 clinical medicineEducación Física y Deportiva0501 psychology and cognitive sciencesOrthopedics and Sports MedicinePsychologyhuman activitiesUS soccerInternational Journal of Performance Analysis in Sport
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Association between playing tactics and creating scoring opportunities in counterattacks from United States Major League Soccer games

2016

The aim of this study was to examine the effects of playing tactics on creating scoring opportunities in counterattacks from the United States Major League Soccer (MLS) 2014 season. The sample included 452 counterattack possessions, corresponding to 30 randomly selected matches. Multidimensional data from 14 categorical variables were analysed by means of a descriptive analysis and binary logistic regression. Counterattacks that started in the pre-offensive zone and had initial penetration were more effective in creating scoring opportunities than those that started in the defensive zone (OR=3.825; 95% IC: 1.765 to 8.289; p<0.01), and those without initial penetration (OR=8.689; 95% IC: 1.1…

05 social sciencesFootballEffectivenesschemical and pharmacologic phenomenaPhysical Therapy Sports Therapy and RehabilitationAdvertisingSample (statistics)030229 sport sciencesFootballLeagueGoal scoring050105 experimental psychologyMatch analysisMatch analysis03 medical and health sciences0302 clinical medicineNotational analysisEducación Física y DeportivaNotational analysis0501 psychology and cognitive sciencesOrthopedics and Sports MedicineMarketingAssociation (psychology)Psychologyhuman activitiesInternational Journal of Performance Analysis in Sport
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De Praepositione: The Emerging of Donatus’s Thought on Syntax?

2020

The paper aims at investigating the syntax treatment in late Antiquity through the analysis of the description of prepositions within Donatus’s Artes. As far as an organic and dedicated description of syntax is concerned, the Roman tradition of grammatical studies in late Antiquity shows an overall gap. However, reflections on syntax emerge from the parts of speech descriptions made by grammarians. The ultimate purpose of this paper is to understand if, and to what extent, traces of emerging thought on syntax can be found in Donatus’s description of prepositions. These are regarded as a syntactic object of study by the modern linguistic theory. To that end, the paper focuses on the textual …

050101 languages & linguisticsHistory05 social sciencesPerspective (graphical)Part of speechSyntaxObject (philosophy)LinguisticsTerminologySettore L-LIN/01 - Glottologia E Linguistica030507 speech-language pathology & audiology03 medical and health sciencesLate AntiquityLatin Donatus Syntax Preposition MetalanguageTheoretical linguistics0501 psychology and cognitive sciences0305 other medical scienceRelation (history of concept)
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Evidential meanings of o eso dicen

2019

En este artículo se analizan los valores del significado evidencial transmitidos por la construcción o eso dicen. Se examinan los distintos patrones discursivos y sintácticos en los que dicha construcción aparece, así como su uso como marca de evidencialidad indirecta. El análisis se realiza a partir del Corpus de Español (sección Web/Dialects) y se centra en la variedad europea del español. Se concluye que o eso dicen transmite diferentes valores de evidencialidad, tales como significado reportativo, rumor y folclore que vienen determinados por factores relacionados con la fijación de la construcción, el tipo de la fuente de información a la que remite y el carácter del ámbito sobre el que…

050101 languages & linguisticsreportativesreportativitéreportative exceptionnalité05 social sciencesreportativosevidentialitySpanishévidentialité050105 experimental psychologyfolcloreexcepcionalidad reportativaespagnolespañol0501 psychology and cognitive sciencesfolkloreevidencialidadreportative exceptionality
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Development and Preliminary Validation of a Sport-Specific Self-Report Measure of Identity Foreclosure

2021

A sport-specific, self-report measure of identity foreclosure was developed through a systematic process that included item pool generation, expert review, administration of items to a development sample of intercollegiate student athletes (N = 326), item evaluation, and administration of scales to validation samples of intercollegiate student athletes (N = 322, N = 54, and N = 64, respectively). The process yielded two four-item scales reflecting commitment to the occupational identity of athlete and one 4-item scale reflecting active exploration of roles other than that of athlete that (a) are internally consistent and temporally stable, (b) demonstrate preliminary factorial and convergen…

050103 clinical psychology03 medical and health sciencesForeclosure (psychoanalysis)0302 clinical medicine05 social sciencesMeasure (physics)Identity (social science)0501 psychology and cognitive sciences030229 sport sciencesSelf reportPsychologySocial psychologyApplied PsychologyJournal of Clinical Sport Psychology
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Sensory and affective components of symptom perception: A psychometric approach

2018

Psychological accounts of symptom perception put forward that symptom experiences consist of sensory-perceptual and affective-motivational components. This division is also suggested by psychometric studies investigating the latent structure of symptom reporting. To corroborate the view that the general and symptom-specific factors of a bifactor model represent affective and sensory components, respectively, we performed bifactor models applying confirmatory factor analytic approaches to the Patient Health Questionnaire-15 and the Checklist for Symptoms in Daily Life completed by 1053 undergraduate students. Additionally, we explored the association of latent factors with negative affectivi…

050103 clinical psychology05 social sciencesSymptom reporting050401 social sciences methodsSensory systemConfirmatory factor analysisNegative affectivityPsychiatry and Mental healthClinical PsychologySymptom perception0504 sociology0501 psychology and cognitive sciencesPsychologyClinical psychology
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Momentary emotion identification in female adolescents with and without anorexia nervosa.

2017

Individuals with anorexia nervosa (AN) often report difficulties in identifying emotions, which have been mostly studied as an alexithymia trait. In a controlled two-day ecological momentary assessment, we studied the influence of time of day and aversive tension on self-reported momentary emotion identification. Analysis on an aggregated level revealed a significant lower mean emotion identification in the AN group. In a mixed model analysis, the AN group showed lower emotion identification than the control group (HC). Both a general and a group effect of time of day were found, indicating that emotion identification improved during the day in HC, whereas a negligible decrease of the emoti…

050103 clinical psychologyAnorexia NervosaTime FactorsAdolescentEmotionsArticleDevelopmental psychology03 medical and health sciences0302 clinical medicineAlexithymiamedicineHumans0501 psychology and cognitive sciencesClinical significanceAffective SymptomsDisordered eatingGroup levelBiological Psychiatry05 social sciencesEmotion identificationmedicine.disease030227 psychiatryPsychiatry and Mental healthAnorexia nervosa (differential diagnoses)Group effectTraitFemaleSelf ReportPsychologyPsychiatry research
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Inclusion of pupils with ADHD symptoms in mainstream classes with PBS

2017

Inclusion is never only a practical issue of placement. School-wide systemic change, together with well-functioning, multi-tiered support, can promote the inclusion of all pupils. This paper draws on research conducted in two mainstream primary schools in Finland. The primary focus was to gain insight into practical solutions to facilitate the inclusion of pupils with attention-deficit hyperactivity disorder (ADHD) in mainstream teaching. Using an experimental, multiple-baseline, single-case design, we examined the effects of Check-in Check-out (CICO) support on changes in the behaviour of two pupils who displayed ADHD-type behaviours. The key features of CICO are brief morning and afternoo…

050103 clinical psychologyEvidence-based practiceinclusive educationylläpitoeducationpositive behaviour supportSingle-subject designmaintenanceEducationDevelopmental psychologyArts and Humanities (miscellaneous)Intervention (counseling)mental disordersmedicinewhole-school approachMainstreamAttention deficit hyperactivity disorderta5160501 psychology and cognitive sciences05 social sciencesBehavior change050301 educationmedicine.diseaseevidence-based interventionssingle-case experimental designsense organsPsychology0503 educationInclusion (education)Report card
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A reliability generalization meta‐analysis of self‐report measures of muscle dysmorphia

2020

This study is a reliability generalization meta‐analysis that reviews continuous measures used to assess muscle dysmorphia (MD): The Muscle Appearance Satisfaction Scale, Muscle Dysmorphic Disorder Inventory, four different versions of the Muscle Dysmorphia Inventory, Adonis Complex Questionnaire, and the Modified Dysmorphia Symptoms Questionnaire. A total of 15,156 individuals from 61 studies provided 73 reliability estimates (alpha coefficients and/or test–retest reliability coefficients) for this meta‐analysis. Random‐ and mixed‐effects models were applied in the statistical analyses. We present the average reliability estimates for each measure, moderator analysis of reliability estimat…

050103 clinical psychologyGeneralizationApplied psychologyinternal consistency reliability03 medical and health sciences0302 clinical medicineSelf-report studytemporal stability reliabilitymedicine0501 psychology and cognitive sciencesmuscle dysmorphiaReliability (statistics)reliability generalizationGovernment05 social sciencesinternal consistency reliability; meta-analysis; muscle dysmorphia; reliability generalization; temporal stability reliabilityTemporal stability reliabilityReliability generalizationmedicine.disease030227 psychiatrymeta-analysisClinical PsychologyMuscle dysmorphiaMeta-analysisPersonalidad Evaluación y Tratamiento PsicológicoInternal consistency reliabilityMeta‐analysisPsychologyMuscle dysmorphia
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