Search results for "EROI"
showing 10 items of 1497 documents
Eriyttäminen lukemaanopetuksessa : seitsemän opettajan kokemukset lukevien koulutulokkaiden eriyttämisestä lukemaanopetuksessa
2001
Solar radiative effects of a Saharan dust plume observed during SAMUM assuming spheroidal model particles
2011
The solar optical properties of Saharan mineral dust observed during the Saharan Mineral Dust Experiment (SAMUM) were explored based on measured size-number distributions and chemical composition. The size-resolved complex refractive index of the dust was derived with real parts of 1.51–1.55 and imaginary parts of 0.0008–0.006 at 550 nm wavelength. At this spectral range a single scattering albedo ω o and an asymmetry parameter g of about 0.8 were derived. These values were largely determined by the presence of coarse particles. Backscatter coefficients and lidar ratios calculated with Mie theory (spherical particles) were not found to be in agreement with independently measured lidar data.…
Sex steroid hormone receptors, their ligands, and nuclear and non-nuclear pathways
2015
The ability of a cell to respond to a particular hormone depends on the presence of specific receptors for those hormones. Once the hormone has bound to its receptor, and following structural and biochemical modifications to the receptor, it separates from cytoplasmic chaperone proteins, thereby exposing the nuclear localization sequences that result in the activation of the receptor and initiation of the biological actions of the hormone on the target cell. In addition, recent work has demonstrated new pathways of steroid signaling through orphan and cell surface receptors that contribute to more rapid, “non-nuclear” or non-transcriptional effects of steroid hormones, often involving G-pro…
Oral and dental health of Italian drug addicted in methadone treatment
2019
Objectives: Our group recorded the characteristic of oro-dental health among a group of drug addicts in recovery treatment with methadone, and it evaluated the changes related to the withdrawal therapy. Methodology: A sample of 50 drug addicts in treatment with methadone was included in this study. At the beginning of the withdrawal therapy, the authors recorded the parameters involved in the most common oral diseases. Moreover, it was evaluated how, during the rehabilitation protocol, the behavioral parameters and the xerostomia that influence the oral health changed. A medical history especially referring to drug addiction features was made. An intraoral objective exam was done for each p…
Yleisten pelikenttien proseduraalisen generoinnin metodit
2016
Proseduraalinen kenttien generointi on viime vuosina noussut indie-pelikehittäjien suosioon, sillä sen avulla voidaan peleihin luoda paljon sisältöä suhteellisen pienellä työmäärällä. Tässä tutkielmassa tarkastellaan yleisten kenttien proseduraalisen generoinnin metodeita. Tarkastelun pohjaksi tutkielmassa käsitellään myös eri kenttätyyppien vaatimuksia ja ominaisuuksia. Lopuksi eri metodityyppejä myös vertaillaan keskenään. In recent years, procedural generation of game levels has risen to popularity among indie game developers, because it enables creation of game content with relatively small workload. In this paper, procedural generation methods of general game levels will be explored. A…
Vokselit tietokonepeleissä
2013
Tässä tutkielmassa selvitettiin vokseleiden käyttöä tietokonepeleissä ja kartoitettiin yleisesti vokselitekniikan hyötyjä, mahdollisuuksia ja ongelmia reaaliaikaisen grafiikan tuottamisessa. Vokseleita verrattiin perinteiseen polygonipohjaiseen esitystapaan ja esiteltiin kuinka vokselitekniikka saattaisi ratkaista joitain polygonipiirron ongelmakohtia. Vokselipiirron todettiin monista hyvistä teknisistä ratkaisuistaan huolimatta kaipaavan yhä huomattavasti lisää tutkimusta, sillä yleinen työkalujen puute, animoinnin vaikeus, muistinkäyttö ja muut ongelmat rajoittavat vokseleiden käyttöä tietokonepeleissä vielä ainakin toistaiseksi. This study examined the usage of voxel technology in video …
Pharmacogenomics: A Step forward Precision Medicine in Childhood Asthma.
2022
Personalized medicine, an approach to care in which individual characteristics are used for targeting interventions and maximizing health outcomes, is rapidly becoming a reality for many diseases. Childhood asthma is a heterogeneous disease and many children have uncontrolled symptoms. Therefore, an individualized approach is needed for improving asthma outcomes in children. The rapidly evolving fields of genomics and pharmacogenomics may provide a way to achieve asthma control and reduce future risks in children with asthma. In particular, pharmacogenomics can provide tools for identifying novel molecular mechanisms and biomarkers to guide treatment. Emergent high-throughput technologies, …
Synthesis, characterization, and cellular investigations of porphyrin– and chlorin–indomethacin conjugates for photodynamic therapy of cancer
2021
Indomethacin is a potent non-steroidal anti-inflammatory drug (NSAID) with a strong selective inhibitor activity towards cyclooxygenase-2 (COX-2), an enzyme that is highly overexpressed in various tumour cells, being involved in tumourigenesis. Concomitantly, porphyrins have gained much attention as promising photosensitizers (PSs) for the non-invasive photodynamic therapy (PDT) of cancer. Herein, we report the design, and determine the singlet oxygen generation capacity and in vitro cellular toxicity of porphyrin- and chlorin-indomethacin conjugates (P2-Ind and C2-Ind). Both the conjugates were obtained in high yields and were characterized by 1H, 19F and 13C NMR as well as by high resolut…
The Brand-Land Identity of Etna Volcano Valley Wines: A Policy Delphi Study
2022
This is the first study on the brand–land link for quality wines with a strong identity produced in extreme territories using the Policy Delphi methodology. The objective of this study is to assess the existence of a relationship between the wine brand and the territory of origin for wines produced in the Etna valley in Sicily (southern Italy). Awareness among producers and stakeholders of the recognizability of local wines by the market was investigated. Moreover, the forecasts/reliability, issues/importance, options/feasibility, and goals/desirability of development factors for wines with a brand–land link in the Etna valley were analyzed. The results were used to design a mod…
Literackie studium uzależnień. Portret Tamary Mortus w "Nocnych zwierzętach" Patrycji Pustkowiak
2016
The article contains presentation of different kinds of addictions connected with female experiences depicted in Patrycja Pustkowiak’s novel The Night Animals. These story arcs create a portrait of the main character based on the literary category of antiheroism and the most important ideas of corporeal feminism. The analysis of the metaphor “the night animals” on the basis of four examples brings the conclusion that social exclusion is caused by alcoholism, drug addiction and hard pornography addiction.