Search results for "Earing"

showing 10 items of 867 documents

Cis-diaminedichloro platinum ototoxicity. An experimental study.

1985

Four groups of guinea pigs received different doses of cis-platinum. SEM and TEM showed a direct relation between the dose and the damage. The first row of OHC is the first one to be damaged. The IHC are more resistant than the OHC. The pattern of destruction is similar to the one produced by the aminoglucoside antibiotics.

medicine.medical_specialtymedicine.drug_classAntibioticsGuinea Pigschemistry.chemical_elementCis-platinumPharmacologyInjections IntramuscularOtotoxicityHair Cells AuditoryMedicineAnimalsHearing LossOrgan of Cortibusiness.industryGeneral Medicinemedicine.diseaseSurgeryMicroscopy Electronmedicine.anatomical_structureOtorhinolaryngologychemistryOrgan of CortiToxicityMicroscopy Electron ScanningKidney Diseasessense organsCisplatinbusinessPlatinumInjections IntraperitonealActa oto-laryngologica
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Steroid and vasoactive treatment for acute deafness after attempted hearing preservation acoustic neuroma surgery.

2004

<i>Objective:</i> To investigate whether intravenous steroid and vasoactive therapy in the acute postoperative period improves hearing outcome in patients who develop acute deafness after attempted hearing preservation surgery for acoustic neuroma (AN) through a retrosigmoid or a middle cranial fossa approach. <i>Study Design and Setting:</i> Retrospective controlled study in a tertiary care center. Thirty-six patients who had developed acute deafness after hearing preservation surgery for treatment of an AN were reviewed. Preoperative AAOHNS hearing class was A in 2, B in 2 and D in 32 patients. Twenty-seven patients were treated with prednisolone, hydroxyethyl star…

medicine.medical_specialtymedicine.drug_classHearing lossmedicine.medical_treatmentPrednisoloneVasodilator AgentsAnti-Inflammatory AgentsAcoustic neuromaDeafnessHydroxyethyl Starch DerivativesPostoperative ComplicationsAcoustic neuroma surgeryVasoactiveotorhinolaryngologic diseasesmedicineEvoked Potentials Auditory Brain StemHumansIn patientPentoxifyllineRetrospective StudiesSalvage TherapyHearing preservationChemotherapybusiness.industryNeuroma Acousticmedicine.diseaseSurgeryOtorhinolaryngologyAnesthesiaAcute DiseaseInjections IntravenousCorticosteroidDrug Therapy Combinationmedicine.symptombusinessORL; journal for oto-rhino-laryngology and its related specialties
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Alteration of the Calcium Content in Inner Hair Cells of the Cochlea of the Guinea Pig after Acute Noise Trauma with and without Application of the O…

1999

Calcium ions are known to be important to the process of signal transduction across the apical and basal sides of the inner hair cells. Calcium channel antagonists have been demonstrated by light microscopy to provide protection against acoustic trauma. To evaluate the protective effect of calcium channel blocker on the inner ear cells to noise exposure, the amount of the histochemical reaction products formed in the cytoplasm of the inner hair cells of the guinea pig after application of pyroantimonate was measured by an image processing system connected to an energy-filtering transmission electron microscope (EFTEM). Compared to untreated control specimens (experimental animal group I) th…

medicine.medical_specialtymedicine.drug_classchemistry.chemical_elementCalcium channel blockerCalciumDiltiazemInternal medicineotorhinolaryngologic diseasesmedicineAnimalsInner earDiltiazemCochleaHair Cells Auditory InnerCalcium channelCalcium Channel BlockersDisease Models AnimalEndocrinologymedicine.anatomical_structureHearing Loss Noise-InducedOtorhinolaryngologychemistryCytoplasmAcute DiseaseCalciumsense organsHair cellmedicine.drugORL
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Leg extension power deficit and mobility limitation in women recovering from hip fracture.

2008

OBJECTIVE: After hip fracture, muscle strength and power remain persistently poor, especially in the fractured leg. This study explores whether asymmetrical leg extension power (LEP) deficit affects mobility in women after proximal femoral fracture (PFF). DESIGN: In this observational study, LEP of both legs, 10- and 50-foot walking speed, and stair-climbing speed were measured in 43 women, aged 73-96, at 1 and 13 wks after surgical repair of PFF. Asymmetrical LEP deficit was calculated as (fractured/(sum both legs)) x 100%. RESULTS: Between weeks 1 and 13 after PFF surgery, LEP increased in the fractured and nonfractured legs by 100% and 30%, respectively. Asymmetrical deficit was reduced …

medicine.medical_specialtymedicine.medical_treatmentArthroplasty Replacement HipPhysical Therapy Sports Therapy and RehabilitationWalkingmedicine.disease_causeWeight-bearingWeight-BearingFracture Fixation InternalPhysical medicine and rehabilitationFracture fixationmedicineHumansMuscle StrengthMobility LimitationAgedAged 80 and overHip fractureRehabilitationbusiness.industryHip FracturesRehabilitationFemoral fractureRecovery of Functionmedicine.diseaseArthroplastyPreferred walking speedMobility LimitationLower ExtremityPhysical therapyExercise TestFemalebusinesshuman activitiesAmerican journal of physical medicine and rehabilitation / Association of Academic Physiatrists
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Newborn hearing-screening project using transient evoked otoacoustic emissions: western sicily experience

2006

Summary Objective To study the incidence of congenital sensorineural hearing loss in all newborns introducing a screen test with a protocol no expensive, with a good “screen sensitivity” that could let an earlier identification of hearing impairment beginning early intervention by 2 months of age and increasing the probability of having language development within the normal range of development. Methods The study was conducted in Sciacca hospital from the beginning of 2003 to our days and was carried out with transient evoked otoacoustic emission using the criteria for PASS or RETEST and considering eventual prenatal and perinatal risk factors. All the newborns were divided into four group…

medicine.medical_specialtymedicine.medical_treatmentHearing Loss SensorineuralOtoacoustic Emissions SpontaneousOtoacoustic emissionNewborn Hearing screeningAudiologyScreen testHearing screeningConsanguinityNeonatal Screeningotorhinolaryngologic diseasesmedicineHumansNormal rangeRehabilitationbusiness.industryIncidence (epidemiology)Hearing TestsIncidenceInfant NewbornGeneral Medicinemedicine.diseaseSettore MED/32 - AudiologiaSettore MED/31 - OtorinolaringoiatriaOtorhinolaryngologySpeech developmentItalyPediatrics Perinatology and Child HealthSensorineural hearing lossbusiness
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Exposure to ototoxic agents and hearing loss: A review of current knowledge

2014

Several experimental and clinical studies have shown that a variety of ototoxic agents (such as drugs, industrial chemicals and noise) can cause sensorineural hearing loss. The most common ototoxic drugs used in clinical practice include: aminoglycoside and macrolide antibiotics, quinoline anti-malarials, platinum analog antineoplastics, loop diuretics, and acetylsalicylic acid. Among chemical agents with potential ototoxic properties are: organic solvents, heavy metals, organotins, nitriles, asphyxiants, and pesticides/herbicides. Acoustic exposure to high intensity and/or prolonged noise can also cause permanent threshold shifts in auditory perception. Ototoxic agents can influence audito…

medicine.medical_specialtypharmacological injuryEndolymphHearing lossototoxicity hearing loss pharmacological injury reactive oxygen speciesPharmacologyAudiologyProinflammatory cytokineSpeech and HearingAtrophyOtotoxicitymedicinehearing lossreactive oxygen specieschemistry.chemical_classificationReactive oxygen speciesbusiness.industrySettore MED/44 - Medicina Del LavoroAminoglycosidemedicine.diseaseototoxicity; hearing loss; pharmacological injury; reactive oxygen speciesSettore MED/32 - AudiologiaototoxicitySettore MED/31 - Otorinolaringoiatriamedicine.anatomical_structureOtorhinolaryngologychemistrySettore BIO/14 - FarmacologiaSensorineural hearing lossmedicine.symptombusinessHearing, Balance and Communication
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Optimization of the Speech Test Material in a Group of Hearing Impaired Subjects: A Feasibility Study for Multilingual Digit Triplet Test Development

2021

Background: The development of the global digit-in-noise test requires optimization of each language version on a group of normal-hearing native-speakers. An alternative solution may be an adaptive optimization during ongoing tests in a group of subjects with unknown hearing impairments. The objective of the research was to compare the optimization results between these groups. Methods: Digit triplets consisting of three pseudo-randomly selected digits were presented in speech-shaped noise at various signal-to-noise ratios (SNRs), according to the protocol of the final speech test. Digit-specific and position-specific speech reception thresholds (SRTs) were determined and compared between g…

medicine.medical_specialtyspeech audiometry; speech intelligibility in noise; digit triplet test; digit-in-noise test; speech reception threshold; tele-audiology; mobile-based hearing testsdigit-in-noise testspeech audiometryAudiologyArticle03 medical and health sciences0302 clinical medicineTest materialotorhinolaryngologic diseasesmedicinemobile-based hearing tests030212 general & internal medicineSpeech reception030223 otorhinolaryngologydigit triplet testGroup (mathematics)tele-audiologyspeech reception thresholdNumerical digitTest (assessment)Continuous noiseNoiseRF1-547OtorhinolaryngologyHearing impairedspeech intelligibility in noisePsychologyAudiology Research
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Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women wi…

2021

AbstractBackgroundDue to increased risk of endometrial and ovarian cancer, women belonging to known Lynch Syndrome (LS) families are recommended to undergo germline testing. Current practice in Finland is to offer counselling to women with pathogenic variant and advocate risk-reducing surgery (RRS) after completion of childbirth. The present study aimed to clarify the impacts of positive germline testing on family planning and reproductive decisions of these women, which are relatively unknown.MethodsSeventy-nine carriers of germline MMR gene pathogenic variant (path_MMR)were identified from the Finnish LS Registry as having genetic testing performed before the age of 45 years and not havin…

medicine.medical_treatmentTestingQH426-470ihmissuhteetCOLORECTAL-CANCER0302 clinical medicinehenkinen hyvinvointi5. Gender equality3123 Gynaecology and paediatricsChildbirthGenetics (clinical)RC254-282media_common0303 health sciencesmedicine.diagnostic_test030305 genetics & heredityNeoplasms. Tumors. Oncology. Including cancer and carcinogensLynch syndrometesting3. Good healthOncologyhereditary cancerFamily planning030220 oncology & carcinogenesissyöpätauditPsychosocialClinical psychologymedia_common.quotation_subject3122 CancersFertilityMUTATION CARRIERSPsychosocial wellbeingtestaus03 medical and health sciencesCHILDBEARINGmedicineGeneticsFERTILITYLynchin oireyhtymäGenetic testingperinnölliset tauditbusiness.industryEndometrial cancerResearchOophorectomyENDOMETRIAL CANCERmedicine.diseaseHereditary cancerperhesuunnitteluLynch syndromerelationshipsRelationshipsbusinesspsychosocial wellbeing
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RC Columns Strengthened with Steel Angles and Battens: Experimental Results and Design Procedure

2013

In this paper, an analytical model for the design of axially loaded strengthened RC columns with steel angles and battens is presented. Cases of directly loaded and not directly loaded steel angles are considered. The model considers the contribution in confinement pressures caused by transverse battens and steel angles and the contribution in terms of the load-carrying capacity of steel angles subjected to axial force and the bending moment. An experimental investigation on the compressive behavior of eight short, confined, RC columns externally strengthened with steel angles and steel battens with various pitches was carried out, and has been utilized as support for the analytical model. …

moment curvatureMaterials sciencebusiness.industryBuilding and ConstructionStructural engineeringStrength of materialsbattenTransverse planeSettore ICAR/09 - Tecnica Delle CostruzioniCompressive strengthArts and Humanities (miscellaneous)BucklingBending momentBearing capacityAxial symmetrybusinessSize effect on structural strengthconcrete steel angles battensCivil and Structural Engineering
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Does English fall on deaf ears? A study of the motivational state of deaf and hard-of-hearing pupils of English

2009

Motivaation katsotaan yleisesti olevan yksi tärkeimmistä vieraan kielen opiskeluun vaikuttavista tekijöistä, ja se onkin sen takia paljon tutkittu ilmiö. Vähemmistöryhmät ovat kuitenkin näissä tutkimuksissa jääneet lähes huomiotta. Esimerkiksi kuurojen ja huonokuuloisten motivaatiota opiskella vieraita kieliä ei juuri ole tutkittu. Hyvänä esimerkkinä on kuitenkin ollut Hanni (2007), joka teki kvalitatiivisen tutkimuksen haastattelemalla seitsemää kuuroa heidän englannin kielen opiskelukokemuksistaan peruskoulusta korkeakouluopintoihin. Koska kaikki kuurot, kuten kaikki kuulevatkaan, eivät mene peruskoulun jälkeen lukioon, saati korkeakouluihin, tarkempi peruskouluvuosien opiskelumotivaation…

motivationhard-of-hearingdeafEFL learning
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