Search results for "Effects"

Luminescence activity of irradiated SiO2-clathrate Melanophlogite

2013

High accuracy Raman measurements using the Stokes and anti-Stokes lines

1997

We show that by measuring the separation between the Stokes and anti-Stokes peaks excited by two different laser lines we obtain a very precise determination of absolute phonon energies. The method is useful for measuring small changes of these energies with strain, temperature, laser power, etc. It doubles the changes and avoids the necessity of using the reference lines in the Raman spectra. The method can be applied for the determination of phonon deformation potentials, for the characterization of strained heteroepitaxial layers, and for micro-Raman analysis of strain in silicon integrated circuits. We give examples of phonon shifts in Si, Ge, GaAs, InAs, and GaP as a function of applie…

Silk Road Museums: Design of Inclusive Heritage and Cross-Cultural Education

2021

This work is the result of a study on the characteristics that define some of the museums created on the Silk Road. The approach to these museums has focused especially on the observation of the educational and heritage aspects that define these institutions. Since 1988, numerous actions related to the Silk Road have been promoted by UNESCO. This old trade route has now become a route of dialogue between cultures. Each museum studied is characterized by promoting local and national issues that define it. Educational issues stand out, since the tradition of silk production is very important in each place. Another aspect observed is that heritage issues manage to strengthen the characteristic…

Site effects assessment through historical and instrumental data integration

2006

ABSTRACT This work illustrates the historical data contribution to the analysis of the microtremor survey results carried out in May 2003 in the city of Palermo by the Istituto Nazionale di Geofisica e Vulcanologia and the Dipartimento di Geologia e Geodesia – University of Palermo. The microtremor survey has been carried out within the project SESAME (Site EffectS assessment using AMbient Excitations) funded by the European Commission, devoted to test the effectiveness of the seismic noise, and in particular of Nakamura technique, in the site effects assessment. The Nakamura technique singles out zones characterized by a near-surface geology suitable to produce site effects, by exploiting …

Side effect management during immune checkpoint blockade using CTLA-4 and PD-1 antibodies for metastatic melanoma – an update

2020

CTLA-4 and PD-1 play a key role in tumor-induced downregulation of lymphocytic immune responses. Immune checkpoint inhibitors have been shown to alter the immune response to various cancer types. Anti-CTLA-4 and anti-PD-1 antibodies affect the interaction between tumor, antigen-presenting cells and T lymphocytes. Clinical studies of the anti-CTLA-4 antibody ipilimumab and the anti-PD-1 antibodies nivolumab and pembrolizumab have provided evidence of their positive effects on overall survival in melanoma patients. Combined treatment using ipilimumab and nivolumab has been shown to achieve five-year survival rates of 52 %. Such enhancement of the immune response is inevitably associated with …

Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas

2022

AbstractInfantile hemangiomas may affect the quality of life (QoL) of patients and their family members, as anxiety and worry may commonly occur in parents, also linked to the social adversion they experience. We underline the beneficial impact of oral propranolol therapy on QoL of patients with infantile hemangiomas (IH) and of their relatives. A specific questionnaire measuring QoL was administered to parents of IH patients at beginning and end of a treatment with oral propranolol. Different aspects were investigated: site of the lesion, age of patients at starting therapy, length of treatment, occurrence of adverse effects and persistence/recurrence of the vascular anomaly. In all cases …

Radiation Hardness Assurance Through System-Level Testing: Risk Acceptance, Facility Requirements, Test Methodology, and Data Exploitation

2021

International audience; Functional verification schemes at a level different from component-level testing are emerging as a cost-effective tool for those space systems for which the risk associated with a lower level of assurance can be accepted. Despite the promising potential, system-level radiation testing can be applied to the functional verification of systems under restricted intrinsic boundaries. Most of them are related to the use of hadrons as opposed to heavy ions. Hadrons are preferred for the irradiation of any bulky system, in general, because of their deeper penetration capabilities. General guidelines about the test preparation and procedure for a high-level radiation test ar…

Analytical Solutions of Viscoelastic Nonlocal Timoshenko Beams

2022

A consistent nonlocal viscoelastic beam model is proposed in this paper. Specifically, a Timoshenko bending problem, where size- and time-dependent effects cannot be neglected, is investigated. In order to inspect scale phenomena, a stress-driven nonlocal formulation is used, whereas to simulate time-dependent effects, fractional linear viscoelasticity is considered. These two approaches are adopted to develop a new Timoshenko bending model. Analytical solutions and application samples of the proposed formulation are presented. Moreover, in order to show influences of viscoelastic and size effects on mechanical response, parametric analyses are provided. The contributed results can be usefu…

Assimilation and Contrast in Spontaneous Comparisons: Heterogeneous Effects of Standard Extremity in Facial Evaluations

2020

Judgments we make about others often depend on the standards we use as comparisons. Investigations into the outcomes of these comparisons and potential moderators have often been limited to single dimensions and preselected standards. The current work instead uses multiple evaluative facial dimensions and a multitude of comparisons. A series of 4 experiments ('N' = 665) attempted to detect contrast from extreme (Study 1) and assimilation to moderate standards in within (Studies 2 and 3) and between-subjects designs (Study 4). Results showed inconsistent evidence for both comparison effects and significant heterogeneity across the evaluative dimensions that were sampled. An additional 5 stud…

PERCEIVED NEIGHBORHOOD VIOLENCE, PARENTING STYLES, AND DEVELOPMENTAL OUTCOMES AMONG SPANISH ADOLESCENTS

2012

This article analyzed perceptions of neighborhood violence of Spanish adolescents (N = 1,015) from authoritative, authoritarian, indulgent, and neglectful families, and its association with three sets of developmental outcomes (psychological, behavioral, and academic). Tests of main and interactive effects were conducted to answer research questions regarding the potential moderating role of perceived neighborhood violence on the relationship between parenting styles and developmental outcomes. Results yielded only main effects of parenting styles and perceived neighborhood violence on developmental outcomes, as well as an interaction between gender and perceived neighborhood violence. Pare…