Search results for "Eliti"

Measuring orthographic transparency and morphological-syllabic complexity in alphabetic orthographies

2017

This narrative review discusses quantitative indices measuring differences between alphabetic languages that are related to the process of word recognition. The specific orthography that a child is acquiring has been identified as a central element influencing reading acquisition and dyslexia. However, the development of reliable metrics to measure differences between language scripts hasn’t received much attention so far. This paper therefore reviews metrics proposed in the literature for quantifying orthographic transparency, syllabic complexity, and morphological complexity of alphabetic languages. The review included searches of Web of Science, PubMed, PsychInfo, Google Scholar, and var…

L2 English vocabulary breadth and knowledge of derivational morphology : One or two constructs?

2022

Derivational morphology (DM) and how it can be assessed have been investigated relatively rarely in language learning and testing research. The goal of this study is to add to the understanding of the nature of DM knowledge, exploring whether and how it is separable from vocabulary breadth. Eight L2 (second or foreign language) English DM knowledge measures and three measures of the size of the English vocabulary were administered to 120 learners. We conducted two confirmatory factor analyses, one with one underlying factor and the other treating vocabulary breadth and DM as separate. As neither model had a satisfactory fit without introducing a residual covariance to the two-factor model,…

Kirsti Siitonen 1951-2020

2020

Lipīdu līmeņa un dislipidēmijas loma holelitiāzes attīstībā

2021

Lipīdu vielmaiņas traucējumiem organismā ir būtiska nozīme. Visbiežāk lipīdu traucējumi tiek skatīti saistībā ar sirds un asinsvadu slimībām, tomēr lipīdu līmeņa nozīmīgas novirzes ir pamatā daudzu citu slimību attīstībai, tajā skaitā holelitiāzes. Holelitiāzes komplikācijas un smaga slimības gaita var novest pie nopietnām, dažreiz pat dzīvībai bīstamām komplikācijām. Mērķis: Analizēt lipīdu un holesterīna līmeņa noviržu (dislipidēmiju) saistību un holelitiāzes attīstību. Uzdevumi: Izpētīt ar holelitiāzes stacionētu pacientu lipidogramas, kā arī ultrasonogrāfijas un computer/dator tomogrāfijas datus, noteikt lipīdu izmaiņas sakarību ar pacientu esošās slimības norisi un smagumu, kā arī vecu…

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

2009

T helper cells secreting interleukin (IL)-17 (Th17 cells) play a crucial role in autoimmune diseases like multiple sclerosis (MS). Th17 differentiation, which is induced by a combination of transforming growth factor (TGF)-beta/IL-6 or IL-21, requires expression of the transcription factor retinoic acid receptor-related orphan receptor gamma t (ROR gamma t). We identify the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR gamma) as a key negative regulator of human and mouse Th17 differentiation. PPAR gamma activation in CD4(+) T cells selectively suppressed Th17 differentiation, but not differentiation into Th1, Th2, or regulatory T cells. Control of Th17 differentia…

Sama koulutus - eri urat : tutkimus Mainzin yliopistossa soveltavaa kielitiedettä vuosina 1965-2001 opiskelleiden suomalaisten urakehityksestä palkka…

2008

The focus of the present study is to describe the connection between the Finnish students’ studies of applied linguistics in the Johannes Gutenberg University, Mainz, Germany, and their later working career. One specific field of competence that all of them have is the skill of German language and the knowledge of German culture. The career development has led some students to become entrepreneurs, some to become freelancers, and some to become salaried employees. The description is longitudinal.Becoming socially aware in a foreign culture is a notable feature in the respondents’ inner growth. This growing awareness is linked as a process to the various stages of their life cycles. By using…

Daptomycin for children in clinical practice experience

2016

Data on daptomycin use in the pediatric setting are scanty. We conducted a multicenter, retrospective study on 46 children treated with intravenous daptomycin at a mean dosage of 7.0 mg/kg/d, for a median of 14 days. Three children had adverse events possibly related to daptomycin. The drug was overall well tolerated, even with prolonged treatment.

Mandatory vaccinations in European countries, undocumented information, false news and the impact on vaccination uptake: the position of the Italian …

2018

Abstract Background High rates of vaccination coverage are important in preventing infectious diseases. Enforcing mandatory vaccinations is one of the strategies that some Countries adopted to protect the community when vaccination coverage is not satisfactory. In Italy, in 2017 vaccination against diphtheria, tetanus, pertussis, hepatitis B, poliovirus, Haemophilus influenzae type b, measles, mumps, rubella and varicella became compulsory in childhood. In order to contrast vaccination policies, anti-vaccination campaigns contribute to the spread of fake news. Among them, there is the false information that Italy is the only one country with mandatory vaccination policy. Aim of our study is…

“Better explanations” in multiple sclerosis diagnostic workup

2019

BackgroundThe exclusion of other diseases that can mimic multiple sclerosis (MS) is the cornerstone of current diagnostic criteria. However, data on the frequency of MS mimics in real life are incomplete.MethodsA total of 695 patients presenting with symptoms suggestive of MS in any of the 22 RIREMS centers underwent a detailed diagnostic workup, including a brain and spinal cord MRI scan, CSF and blood examinations, and a 3-year clinical and radiologic follow-up.FindingsA total of 667 patients completed the study. Alternative diagnoses were formulated in 163 (24.4%) cases, the most frequent being nonspecific neurologic symptoms in association with atypical MRI lesions of suspected vascular…

Treatment of experimental autoimmune encephalomyelitis with adenylate deaminase from Penicillium lanoso-viride.

2000

The effect of intramuscularly administered immunomodulator, adenylate deaminase (E.C. 3.5.4.6), from Penicillium lanoso-viride on the clinical score of acute experimental autoimmune encephalomyelitis (EAE), a T cell-mediated autoimmune disease, was examined by inoculation of guinea pigs with rabbit brain and spinal cord homogenate (encephalitogen) and complete Freund's adjuvant. Adenylate deaminase (ADA) was effective in delaying the onset of clinical disease. ADA inhibited the severity of EAE. There was a significant decrease in clinical signs. A decrease in the number of morbid and dead animals was observed. Of ADA treated animals, 50-80% developed no clinical manifestations of EAE. The o…